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Antioxidant Activity of Secondary Metabolites of Teucrium Species

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Teucrium Species: Biology and Applications

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Abstract

Teucrium species are characterized by valuable secondary metabolites content and long traditional ethnopharmacological use. Bearing in mind that the therapeutic benefit of medicinal plants is often based on their antioxidant activity, this chapter is a comprehensive review of the antioxidant activity of medicinal and potentially medicinal species of the genus Teucrium, as well as the secondary metabolites content and diversity including methods for antioxidant activity determination. Analysis of the current literature indicates that antioxidant activity has been tested for over 30 species of this genus using different methodological approaches. Tucrium polium is the most tested species followed by Teucrium chamaedrys and Tucrium montanum. Plant extracts are often used for antioxidant activity analysis followed by essential oils and isolated chemical compounds. The most commonly used methods include DPPH – 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity, Ferric Reducing Antioxidant Power (FRAP), β-carotene/linoleic acid assay, 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging capacity (ABTS) etc. Teucrium species is characterized by the presence of monoterpenes and sesquiterpenes, as well as flavonoids, phenylethanoids and phenolic acids. The significant correlation of the antioxidant activity and phenolic content was determined in many studies. The antioxidant potential of some Teucrium species has been confirmed by in vivo testing. Variability during vegetative period, habitat-related variability as well as variability between plant parts were determined for the antioxidant activity and content of the active compounds of some Teucrium species. Numerous studies confirm that species of the genus Teucrium possess secondary metabolites with significant antioxidant effects.

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Abbreviations

ABTS:

2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging capacity

BDE:

Bond dissociation energy

BR:

Briggs-Rauscher oscillating reaction

CUPRAC:

Cupric Reducing Antioxidant Capacity assay

DPPH:

2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity

EPR:

Electron Paramagnetic Resonance radicals detection

FRAP:

Ferric Reducing Antioxidant Power

HAPX:

Hemoglobin Ascorbate Peroxidase activity inhibition

HAT:

Hydrogen atom transfer

HRSA:

Hydroxyl Radical Scavenging Activity

IP:

Ionization potential

NBT/riboflavine:

Nitroblue Tetrazolium riboflavine assay

ORAC:

Oxygen Radical Absorbance Capacity

OSI:

Oxidative Stability Index

RP:

Reducing Power

SET:

Single electron transfer

SOD :

Superoxide Dismutase Activity assay

SRSA:

Superoxide Radical Scavenging Activity

TAC:

Total Antioxidant Capacity

TAP:

Total Antioxidant Power

TBA:

Thiobarbituric Acid Assay

TEAC:

Trolox Equivalent Antioxidant Capacity

X/XOD:

Xanthine/Xanthine Oxidase assay

XOA:

Xanthine Oxidase Activity assay

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  1. Department of Biology and Ecology, Faculty of Science, University of Kragujevac, Kragujevac, Serbia

    Milan Stanković

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    Milan Stanković

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Stanković, M. (2020). Antioxidant Activity of Secondary Metabolites of Teucrium Species. In: Stanković, M. (eds) Teucrium Species: Biology and Applications. Springer, Cham. https://doi.org/10.1007/978-3-030-52159-2_10

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