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Virus-like particle vaccinology, from bench to bedside
Nature
Virus-like particles (VLPs) have become key tools in biology, medicine and even engineering. After their initial use to resolve viral...
25 months ago
Platforms, advances, and technical challenges in virus-like particles-based vaccines
Frontiers
In this review article, we focus on the advantages and disadvantages of various VLP-producing platforms, recent advances and technical challenges in VLP...
7 months ago
Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization | Scientific Reports
Nature
Virus-like particles (VLPs) are non-infectious self-assembling nanoparticles, useful in medicine and nanotechnology.
104 months ago
Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo
Nature
Here we report prime editor engineered virus-like particles (PE-eVLPs) that deliver prime editor proteins, prime editing guide RNAs and nicking single guide...
8 months ago
Escherichia coli-derived virus-like particles in vaccine development - npj Vaccines
Nature
Recombinant virus-like particle-based vaccines are composed of viral structural proteins and mimic authentic native viruses but are devoid...
91 months ago
Minimal system for assembly of SARS-CoV-2 virus like particles - Scientific Reports
Nature
Here we demonstrate that non-infectious SARS-CoV-2 virus like particles (VLPs) can be assembled by co-expressing the viral proteins S, M and E in mammalian...
45 months ago
Programmable polymorphism of a virus-like particle
Nature
Virus-like particles (VLPs) have significant potential as artificial vaccines and drug delivery systems. The ability to control their size...
31 months ago
A heterogeneous human immunodeficiency virus-like particle (VLP) formulation produced by a novel vector system
Nature
First identified as the etiological agent behind Acquired Immunodeficiency Syndrome (AIDS) in the early 1980s, HIV-1 has continued to spread...
80 months ago
Construction of SARS-CoV-2 virus-like particles in plant - Scientific Reports
Nature
The pandemic of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused a public health emergency, and research on the...
32 months ago
A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection
Nature
Chikungunya virus (CHIKV) is an emerging infectious agent that can cause severe disease in humans and against which there is presently no...
176 months ago