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Reassessment of marker genes in human induced pluripotent stem cells for enhanced quality control

Nature
Human induced pluripotent stem cells (iPSCs) have great potential in research, but pluripotency testing faces challenges due to non-standardized methods and...
6 days ago

Molecular Markers Star in Latest Guidance for Head and Neck Tumors

Radiological Society of North America | RSNA
Genomics has revolutionized tumor taxonomy and classification, and rapid advances in molecular imaging place radiologists at the helm.
5 days ago

Immunohistochemistry and immunofluorescence: adapting to the needs of life science researchers

BioTechniques
Immunohistochemistry is a protein-detection technique that uses antibodies to identify antigen markers present in a tissue sample. The antibodies are tagged...
5 days ago

Generation of human-pig chimeric renal organoids using iPSC technology

Nature
Porcine organs and human induced pluripotent stem cell (iPSC)-derived organoids as alternative organs for human transplantation have garnered attention,...
23 hours ago

The fetal origins of metabolic health: exploring the association between newborn biological age and metabolism hormones in childhood

BMC Medicine
Telomere length (TL), mitochondrial DNA copy number (mtDNAcn), and DNA methylation age (DNAmAge) are common aging biomarkers. However, research on the...
5 hours ago

Detection and isolation of brain tumors in cancer patients using neural network techniques in MRI images

Nature
MRI imaging primarily focuses on the soft tissues of the human body, typically performed prior to a patient's transfer to the surgical suite for a medical...
1 day ago

Comprehensive transcriptomic analysis identifies three distinct subtypes of pituitary adenomas: insights into tumor behavior, prognosis, and stem cell characteristics

Journal of Translational Medicine
Pituitary adenomas (PAs) are the second most common intracranial tumor. While current diagnostic practices rely primarily on histological testing,...
5 days ago

Profiling neuroinflammatory markers and response to nusinersen in paediatric spinal muscular atrophy

Nature
Neuroinflammation is an emerging clinical feature in spinal muscular atrophy (SMA). Characterizing neuroinflammatory cytokines in cerebrospinal fluid (CSF)...
5 hours ago

Genome-wide association study of cassava brown streak disease resistance in cassava germplasm conserved in South America

Nature
Cassava (Manihot esculenta Crantz) is a vital carbohydrate source for over 800 million people globally, yet its production in East Africa is severely...
4 days ago

Analyses of whole-genome sequences from 185 North American Thoroughbred horses, spanning 5 generations

Nature
Whole genome sequences (WGS) of 185 North American Thoroughbred horses were compared to quantify the number and frequency of variants, diversity of...
6 days ago