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Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy
Nature
Aficamten, a selective small-molecule inhibitor of cardiac myosin that diminishes ATPase activity by strongly slowing phosphate release, stabilizing a weak...
3 months ago
Shoring up dyads in heart muscle with gene therapy
Boston Children's Answers
Our heart muscle is studded with tiny dyads, intricately designed structures that manage incoming electrical signals and calcium release to...
1 month ago
NBCNews.com: Scientists Found Tiny Nanoplastics in People’s Arteries; Their Presence Was Tied to a Higher Risk of Heart Disease
Cedars-Sinai
NBCNews.com recently interviewed Martha Gulati, MD, director of Preventive Cardiology in the Smidt Heart Institute at Cedars-Sinai,...
6 months ago
Tiny deletion in heart muscle protein briefly affects embryonic ventricles but has long-term effects on adult atrial fibrilla
University of Alabama at Birmingham
Now, in a study in zebrafish and human heart muscle cells, researchers show that a tiny deletion in the A-band of titin — the loss of just nine...
3 months ago
Small pump for kids awaiting heart transplant shows promise in Stanford Medicine-led trial
Stanford Medicine
A new type of surgically implanted pump that can support a child's failing heart has passed the first stage of human testing in a Stanford...
6 months ago
Tiny killers: How autoantibodies attack the heart in lupus patients
Medical Xpress
Lupus is characterized by a large number of autoantibodies, immune proteins that mistakenly target a person's own tissues or organs.
2 months ago
Tiny New Invention Diagnoses Heart Attacks in Minutes, Could Save Lives on the Spot
SciTechDaily
A new blood test can diagnose it in minutes instead of hours and could be adapted for use by first responders or even at home.
3 weeks ago
Long Term Cognitive Function After Cardiac Arrest: A Mini-Review
Frontiers
This narrative mini-review, explores available evidence on hypoxic brain injury and long-term cognitive function in cardiac arrest survivors.
4 months ago
Protein study reveals how the tiny shrew achieves a resting heart rate of 1,020 beats per minute
Phys.org
The shrew's resting heart rate can reach up to 17 beats per second, equivalent to about 1020 beats per minute. In comparison, the average...
1 month ago
The 1,000th patient! Carolyn lives her best life with tiny heart device
WellSpan Health
The Watchman device treats a condition called AFib and allows patients to avoid blood-thinning medications.
2 months ago