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Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses

Nature
The tumor microenvironment can inhibit the efficacy of cancer therapies through mechanisms such as poor trafficking and exhaustion of immune cells.
4 days ago

Long-term trial data boosts case for newer drug-resistant TB regimens

CIDRAP
Extended follow-up on patients in a phase 3 clinical trial found that two bedaquiline-containing drug regimens for rifampicin-resistant tuberculosis (TB)...
6 days ago

Promising research offers hope in the fight against resistant bacteria

News-Medical
Antibiotic resistant bacteria threaten global health. Nevertheless, few new antibiotics have come onto the market in the last 50 years.
5 days ago

The Antimicrobial Resistance Pandemic: Breaking the Silence

American Society for Microbiology
Antimicrobial resistance (AMR) is called a “silent pandemic” because of the way it lurks, unnoticed and underdiscussed, while wreaking havoc and claiming...
7 hours ago

Phage cocktail shows promise against drug-resistant bacteria

Phys.org
Researchers have a new battle tactic to fight drug-resistant bacterial infections. Their strategy involves using collections of bacteriophages, viruses that...
4 days ago

Gotistobart Plus Pembrolizumab Shows Activity in Platinum-Resistant Ovarian Cancer

OncLive
Gotistobart plus pembrolizumab demonstrated antitumor activity and a manageable safety profile in platinum-resistant ovarian cancer.
1 day ago

Nonviolent resistance in Palestine is more dangerous than ever — but it’s the only way forward

Waging Nonviolence
We will not build a better future for all people by killing or dominating each other. Only a nonviolent movement with vision and strategy can.
1 day ago

Antiviral-Resistant Variants of SARS-CoV-2 Can Emerge in Immunocompromised People

Infectious Disease Special Edition
Immunocompromised people with persistent COVID-19 infections can harbor drug-resistant variants of the SARS-CoV-2 virus, which have the potential to spread...
1 day ago

Bedaquiline versus injectable containing regimens for rifampicin-resistant and multidrug-resistant tuberculosis in a reference center in Brazil – a real-world evidence study using a retrospective design

BMC Infectious Diseases
Drug resistance (DR) is one of the several challenges to global tuberculosis (TB) control. The implementation of bedaquiline (BED) for DR-TB after more than...
1 day ago

Strategies for Preventing Antibiotic Resistant Bacteria from Contaminating Food

Food Poisoning News
Antibiotic-resistant bacteria are strains of bacteria that have evolved the ability to survive or grow despite the presence of antibiotics that would...
6 days ago