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Propofol disrupts the functional core-matrix architecture of the thalamus in humans

Nature
This research bridges cellular and systems-level understanding, highlighting the crucial role of thalamic core–matrix functional architecture.
3 weeks ago

A New Use for Propofol in Treating Epilepsy?

WCM Newsroom
Drug developers consider inhibiting HCN1 a promising strategy for treating neurologic disorders including epilepsy and chronic pain. The...
2 months ago

Study reveals how an anesthesia drug induces unconsciousness

MIT News
Propofol, a drug commonly used for general anesthesia, induces unconsciousness by disrupting the brain's normal balance between stability...
2 months ago

Comparative Analysis of the Therapeutic Efficacy of Remimazolam Tosylate and Propofol in Older Adults Undergoing Painless Endoscopic Retrograde

Frontiers
Objective: The aim of this study is to conduct a comparative analysis of the therapeutic outcomes associated with the administration of...
3 days ago

FDA Approves Amneal Propofol Injectable Emulsion Single-Dose Vials

Anesthesiology News
This single dose formulation of propofol is an essential medicine utilized every day by hospitals for surgical use.
1 month ago

How Propofol Disrupts Consciousness Pathways

Neuroscience News
Researchers have mapped how propofol, a widely used anesthetic, alters brain connectivity to induce unconsciousness.
3 weeks ago

FDA Approves Amneal Propofol Injectable Emulsion Single-Dose Vials

Gastroenterology & Endoscopy News
Propofol is an IV drug commonly used for the induction and maintenance of anesthesia and sedation that is currently on the ASHP drug shortages list due to...
1 month ago

Impact of propofol versus desflurane anesthesia on postoperative hepatic and renal functions in infants with living-related liver transplantation: a randomized controlled trial

BMC Medicine
The effects of anesthetics on liver and kidney functions after infantile living-related liver transplantation (LRLT) are unclear.
2 weeks ago

Unlocking Propofol’s Potential in Epilepsy Treatment

University of Miami
Unlocking Propofol's Potential in Epilepsy Treatment · Miller School researcher Dr. Xiaoan Wu co-led a study on a drug that may treat pain and...
1 month ago

Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants

Nature
We found that propofol restored voltage-dependent closing in two HCN1 epilepsy-associated polymorphisms that act by destabilizing the channel closed state.
2 months ago