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neurons in dorsal bed nucleus of the stria terminalis for mediating depression-related behaviors

Nature
Dopamine (DA) neurons play a crucial role in the development and manifestation of depression, as well as in response to antidepressant...
5 days ago

Editorial: Brain dopaminergic mechanisms

Frontiers
Dopamine release is spatiotemporally regulated by multiple mechanisms, including tonic and phasic, axonal and somatodendritic, somatic activity-driven and...
3 months ago

Neurovascular and immune factors of vulnerability of substantia nigra dopaminergic neurons in non-human primates

Nature
Dopaminergic neurons in the ventral tier of the substantia nigra pars compacta (SNc) degenerate prominently in Parkinson's disease (PD),...
3 months ago

Hemispheric differences in the mesostriatal dopaminergic system

Frontiers
The mesostriatal dopaminergic system, which comprises the mesolimbic and the nigrostriatal pathways, plays a major role in neural processing underlying...
3 months ago

Learning to express reward prediction error-like dopaminergic activity requires plastic representations of time

Nature
The dominant theoretical framework to account for reinforcement learning in the brain is temporal difference learning (TD) learning,...
2 months ago

Degeneration of Dopaminergic Neurons Due to Metabolic Alterations and Parkinson’s Disease

Frontiers
We review recent studies and provide new insight on the link between metabolic diseases and the degeneration of dopaminergic neurons, which consequently leads...
3 months ago

Calbindin and Girk2/Aldh1a1 define resilient vs vulnerable dopaminergic neurons in a primate Parkinson’s disease model

Nature
Calbindin is the marker that best identifies the most resilient neurons located in the dorsal tier and ventral tegmental area.
1 month ago

Direct Glutamatergic Signaling From Midbrain Dopaminergic Neurons Onto Pyramidal Prefrontal Cortex Neurons

Frontiers
The ability to release glutamate from a subpopulation of the VTA dopaminergic neurons has been shown to control the prefrontal cortex (PFC) excitation.
3 months ago

A feature-specific prediction error model explains dopaminergic heterogeneity

Nature
We introduce a complementary 'feature-specific RPE' model, positing that individual ventral tegmental area DA neurons report RPEs for different aspects of an...
3 months ago

Dopaminergic neurodegeneration in Gerstmann–Sträussler–Scheinker (P102L) disease: insights from imaging and pathological examination

Frontiers
Gerstmann–Sträussler–Scheinker (GSS) disease is an inherited prion disease characterized by dementia, cerebellar ataxia, and painful sensory...
2 weeks ago