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Caffeine may help treat alcoholism by blocking dopamine

GIGAZINE
Alcohol and caffeine, both found in a variety of beverages, are chemicals that affect people's lives around the world and have been widely studied for their...
13 hours ago

Yin Yang 1 and guanine quadruplexes protect dopaminergic neurons from cellular stress via transmissive dormancy

Nature
Neurons deploy diverse adaptive strategies to ensure survival and neurotransmission amid cellular stress. When these adaptive pathways are overwhelmed,...
19 hours ago

Circulating prolactin levels and the effect of dopaminergic agonists in systemic lupus erythematosus: a systematic review and meta-analysis

Nature
This systematic review of clinical studies investigated whether circulating PRL levels differed between subjects with systemic lupus erythematosus (SLE) and...
1 day ago

Molecular Blueprint Could Redesign Parkinson’s Disease Therapeutics

Genetic Engineering and Biotechnology News
GPR6, a G protein-coupled receptor, is primarily expressed in the medium spiny neurons of the striatum, specifically within the striatopallidal pathway.
1 day ago

Stem cell therapy TED-A9 showing safety and early efficacy in trial

Parkinson's News Today
Easing of symptoms, no related side effects seen in 6 adults one year after TED-A9 given as low or high dose transplant in Phase 1 /2 trial.
2 days ago

Transgenerational neurotoxic effects of triphenyltin on marine medaka: impaired dopaminergic system function

ScienceDirect.com
Triphenyltin (TPT), a widely used environmental contaminant in antifouling paints, is known for its neurotoxic effects. To investigate the multigenerational...
2 days ago

Progressive noradrenergic degeneration and motor cortical dysfunction in Parkinson’s disease

Nature
The locus coeruleus norepinephrine (LC-NE) system plays an important role in regulating brain function, and its neuronal loss has been well-documented in...
1 week ago

The Parkinson’s disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons

Molecular Neurodegeneration
Variants in the CTSB gene encoding the lysosomal hydrolase cathepsin B (catB) are associated with increased risk of Parkinson's disease (PD).
1 week ago

The dopaminergic system mediates the lateral habenula-induced autonomic cardiovascular responses

Frontiers
The dopaminergic system mediates the lateral habenula-induced autonomic cardiovascular responses ... The lateral habenula (LHb) has been implicated in stress...
2 weeks ago

Caffeine’s impact on brain’s mesolimbic dopaminergic pathway could reduce alcohol’s addictive effects

MSN
Scientists have recently discovered that caffeine may counteract some of alcohol's effects on the brain's reward system, particularly by blocking certain...
2 weeks ago