Activation of midbrain dopamine neurons rapidly inhibits action potential firing in both direct- and indirect-pathway striatal projection...
145 months ago

Deposition of amyloid-β (Aβ) in the brain can impair neuronal function and contribute to cognitive decline in Alzheimer's disease (AD).
3 months ago

Overcoming aversive emotional memories requires neural systems that detect when fear responses are no longer appropriate so that they can be...
77 months ago

The three factors were able to elicit dopaminergic neuronal conversion in prenatal and adult fibroblasts from healthy donors and Parkinson's disease patients.
160 months ago

These data provide a link between DA neural activity, resilience and resilience-associated behaviour during the experience of stress.
25 months ago

In a preclinical study, dopaminergic neurons derived from human induced pluripotent stem cells were implanted into a primate model of...
87 months ago

The retention of episodic-like memory is enhanced, in humans and animals, when something novel happens shortly before or after encoding.
98 months ago

Here we identify Cav2.3 channels as regulators of nigral neuronal viability. Cav2.3 transcripts were more abundant than other voltage-gated Ca 2+ channels in...
60 months ago

VTA dopaminergic neurons are necessary for arousal and that their inhibition suppresses wakefulness, even in the face of ethologically relevant salient stimuli.
98 months ago

The studies reviewed here provide evidence that acute ketamine administration leads to dopamine release in the rodent brain.
85 months ago