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An antioxidant screen identifies ascorbic acid for prevention of light-induced mitotic prolongation in live cell imaging
Nature
We demonstrate that adding ascorbic acid to the media enables fluorescence imaging of mitotic events at very high temporal resolution without obvious...
13 months ago
Ascorbic acid inhibits transcriptional activities of LXRα to ameliorate lipid metabolism disorder
ScienceDirect.com
Ascorbic acid inhibited expression of the genes for lipid synthesis by reducing LXRα nuclear translocation and activating AMPKα.
35 months ago
Ineffectiveness of Ascorbic Acid Therapy in Nephropathic Cystinosis
The New England Journal of Medicine
High concentrations of ascorbic acid (0.57 mM) lower the free (nonprotein) cystine content of cultured cystinotic skin fibroblasts by over 50 per cent.
548 months ago
Ascorbic acid is associated with favourable hormonal profiles among infertile males
Frontiers
Our findings show that ascorbic acid is associated with higher testosterone levels and improved androgenic status in infertile males.
17 months ago
Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival
Nature
We conclude that Slc23a1 is required for transport of ascorbic acid into many tissues and across the placenta. Deficiency of the transporter is...
271 months ago
Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma
ScienceDirect.com
In addition, ascorbic acid was associated with fewer adverse effects than imiquimod. Our results demonstrate that concentrated ascorbic acid in DMSO is a well...
33 months ago
Inhibitory Effect of Ascorbic Acid on in vitro Enzymatic Digestion of Raw and Cooked Starches
Frontiers
The aim of this study was to explore the inhibitory effects of ascorbic acid at various concentrations on the in vitro digestion of high amylose maize starch (...
5 months ago
Ascorbic acid as an adjunctive therapy in critically ill patients with COVID-19: a propensity score matched study
Nature
Low dose of ascorbic acid as an adjunctive therapy in COVID-19 critically ill patients was not associated with mortality benefits, but it was associated with a...
39 months ago
Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts
Nature
Ascorbic acid (AA) is widely used in cosmetic formulations due to its antioxidant property and ability to increase collagen synthesis.
70 months ago
Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes
Nature
L-ascorbic acid (Vitamin C) can enhance the meiotic maturation and developmental competence of porcine oocytes, but the underlying molecular...
79 months ago