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Synthesis and biological evaluation of novel aminoguanidine derivatives as potential antibacterial agents

Nature
In an effort to identify novel antibacterial agents, we presented two series of aminoguanidine derivatives that were designed by incorporating 1,2,4-triazol...
4 weeks ago

Repurposing Benzbromarone as an Antibacterial Agent against Gram-Positive Bacteria

ACS Publications
The rise of antibiotic-resistant Gram-positive pathogens, particularly methicillin-resistant Staphylococcus aureus (MRSA), presents a significant challenge...
2 weeks ago

Transforming polyethylene: From functionalization to antibacterial properties for sustainable applications

Phys.org
Transforming polyethylene: From functionalization to antibacterial properties for sustainable applications ... Polyethylene (PE) is one of the most widely used...
3 weeks ago

Mycosynthesis of silver nanoparticles from endophytic Aspergillus parasiticus and their antibacterial activity against methicillin-resistant Staphylococcus aureus in vitro and in vivo

Frontiers
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a drug-resistant and biofilm-forming pathogenic bacteria with severe morbidity and...
4 weeks ago

Zai Lab and Pfizer Announce Strategic Collaboration on the Novel Antibacterial Drug XACDURO

Business Wire
Zai Lab (“Zai Lab”, NASDAQ: ZLAB; HKEX: 9688) and Pfizer (“Pfizer”, NYSE: PFE) announced today a strategic collaboration for the novel antibacterial d.
1 week ago

Synthetic indole derivatives as an antibacterial agent inhibiting respiratory metabolism of multidrug-resistant gram-positive bacteria

Nature
The survival of modern medicine depends heavily on the effective prevention and treatment of bacterial infections, are threatened by antibacterial...
3 weeks ago

Hyaluronan Scaffold Decorated with Bifunctional Peptide Promotes Wound Healing via Antibacterial and Anti-Inflammatory

ACS Publications
The invasion of bacteria and inflammation impeded infected wounds heal. Here, a hyaluronan-based scaffold (HAG-g-C) was designed by cross-linking with...
6 days ago

Novel biocompatible magnetron-sputtered silver coating for enhanced antibacterial properties and osteogenesis in vitro

Nature
Peri-implant infection is a serious complication in orthopedic surgery. This study aimed to reduce the incidence of peri-implant infection by developing a...
2 weeks ago

Unveiling the Antibacterial Efficacy of a Benzonitrile Small Molecule, IITR00210, in Shigella Infection

ACS Publications
The escalating prevalence of bacterial infections and the rapid emergence of multidrug-resistant Gram-negative bacterial pathogens highlight an urgent...
4 days ago

Exploring northeast India’s culturable soil Actinomycetia for potent antibacterial agents against gram-positive bacterial pathogens of clinical importance

Nature
This study investigated the isolation and bioactivity of Actinomycetia from the soil of Northeast India, a region rich in microbial diversity.
2 weeks ago