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Biological function of sialic acid and sialylation in human health and disease
Nature
Sialic acids are predominantly found at the terminal ends of glycoproteins and glycolipids and play key roles in cellular communication and...
1 month ago
Single-molecule imaging reveals allosteric stimulation of SARS-CoV-2 spike receptor binding domain by host sialic acid
Science | AAAS
We demonstrate that SA binding to the NTD allosterically shifts the S conformational equilibrium, favoring enhanced exposure of the ACE2-binding site.
3 months ago
Sialic Acid-Functionalized Gold Nanoparticles for Sensitive and Selective Colorimetric Determination of Serotonin
ACS Publications
We have developed a new colorimetric method that uses sialic-acid-coated gold nanoparticles (SA-AuNPs) with plasmonic properties for the...
5 months ago
Dendritic Cells: A Spot on Sialic Acid
Frontiers
This review focuses on the developmental regulation of DC surface sialic acids and how manipulation of DC surface sialic acids can affect immune-critical DC...
8 months ago
Potential effects of sialic acid and 3′-Sialyllactose on intestinal health and anti-cardiovascular disease in mice fed with a high-fat diet
ScienceDirect.com
This study investigated the beneficial effects of sialic acid (SA) and 3′-Sialyllactose (3′-SL) on the intestinal and cardiovascular health of mice fed with a...
5 months ago
Figure 1 - Sialic Acid Receptor Specificity in Mammary Gland of Dairy Cattle Infected with Highly Pathogenic Avian Influenza A(H5N1) Virus - Volume 30, Number 7—July 2024 - Emerging Infectious Diseases journal
Centers for Disease Control and Prevention (.gov)
Figure 1 · November 2024 · Infectious Diseases and Carceral Health Supplement · Early Release · Past Issues · July 2024 · Sialic Acid Receptor Specificity in...
4 months ago
Sialic acid in the regulation of blood cell production, differentiation and turnover - Irons - 2024 - Immunology
Wiley Online Library
We conclude that sialylation is a critical post-translational modification utilized in haematopoiesis to meet the dynamic needs of the organism.
7 months ago
MHC class II proteins mediate sialic acid independent entry of human and avian H2N2 influenza A viruses
Nature
Influenza A viruses (IAV) pose substantial burden on human and animal health. Avian, swine and human IAV bind sialic acid on host glycans as...
3 months ago
β-Cyclodextrin-Tethered Butein, a Greener Redox-Active Biomaterial for Electrochemical Enzymatic Sensing of Sialic Acid
ACS Publications
An enzymatic biomolecular sensor has been constructed using BCD-Butein-modified glassy carbon and a screen-printed electrode targeting sialic acid as the model...
4 months ago
Characterization of milk oligosaccharide and sialic acid content and their influence on brain sialic acid in a lean mouse model for gestational diabetes
ScienceDirect.com
We hypothesize that HIP and high-fat diet influence milk oligosaccharide composition, particularly sialylated oligosaccharides.
8 months ago