αβ T cell receptors (αβTCRs) co-recognise antigens when bound to Major Histocompatibility Complex (MHC) or MHC class I-like molecules.
2 days ago

Synapses are organized into nanocolumns that control synaptic transmission efficacy through precise alignment of postsynaptic...
2 days ago

TransTACs are engineered to drive rapid co-internalization of a target protein of interest and TfR1 from the cell surface, and to enable target...
3 weeks ago

The μ-opioid receptor (μOR), a prototypical G protein-coupled receptor (GPCR), is the target of opioid analgesics such as morphine and...
4 days ago

Since 2019, SARS-CoV-2 has undergone mutations, resulting in pandemic and epidemic waves. The SARS-CoV-2 spike protein, crucial for cellular...
6 days ago

Scientists have identified the melatonin MT1 receptor as a key regulator of REM sleep, crucial for memory, dreaming, and emotional regulation.
3 weeks ago

The brain helps us survive by forming internal representations of the external world1,2. Excitatory cortical neurons are often precisely...
2 weeks ago

N-methyl-D-aspartate (NMDA) receptors are ionotropic glutamate receptors involved in learning and memory. NMDA receptors primarily comprise two GluN1 and...
10 hours ago

Oxytocin has various effects ranging from promoting labor in pregnant women to alleviating stress. Recently, we reported the hair...
10 hours ago

Triple negative breast cancer (TNBC) is one of the most difficult of all types of breast cancer to treat. TNBC is characterized by the...
9 hours ago