WO2015075653A3 - Multi-well plates and methods of use thereof - Google Patents

Multi-well plates and methods of use thereof Download PDF

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Publication number
WO2015075653A3
WO2015075653A3 PCT/IB2014/066178 IB2014066178W WO2015075653A3 WO 2015075653 A3 WO2015075653 A3 WO 2015075653A3 IB 2014066178 W IB2014066178 W IB 2014066178W WO 2015075653 A3 WO2015075653 A3 WO 2015075653A3
Authority
WO
WIPO (PCT)
Prior art keywords
plate
methods
well plates
well
specifically
Prior art date
Application number
PCT/IB2014/066178
Other languages
French (fr)
Other versions
WO2015075653A2 (en
Inventor
Shlomo Turgeman
Ben Zion LAVI
Eitan SHEFFER
Original Assignee
Idea Machine Development Design & Production Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idea Machine Development Design & Production Ltd. filed Critical Idea Machine Development Design & Production Ltd.
Priority to CN201480063117.2A priority Critical patent/CN105899294B/en
Priority to EP14830870.3A priority patent/EP3071332A2/en
Priority to CA2931068A priority patent/CA2931068C/en
Priority to JP2016553758A priority patent/JP6553071B2/en
Publication of WO2015075653A2 publication Critical patent/WO2015075653A2/en
Publication of WO2015075653A3 publication Critical patent/WO2015075653A3/en
Priority to US15/157,428 priority patent/US9827566B2/en
Priority to US15/795,294 priority patent/US10758907B2/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/523Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50855Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using modular assemblies of strips or of individual wells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F13/00Apparatus for measuring by volume and delivering fluids or fluent solid materials, not provided for in the preceding groups
    • G01F13/006Apparatus for measuring by volume and delivering fluids or fluent solid materials, not provided for in the preceding groups measuring volume in function of time
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F13/00Apparatus for measuring by volume and delivering fluids or fluent solid materials, not provided for in the preceding groups
    • G01F13/008Apparatus for measuring by volume and delivering fluids or fluent solid materials, not provided for in the preceding groups taps comprising counting- and recording means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F15/00Details of, or accessories for, apparatus of groups G01F1/00 - G01F13/00 insofar as such details or appliances are not adapted to particular types of such apparatus
    • G01F15/001Means for regulating or setting the meter for a predetermined quantity
    • G01F15/003Means for regulating or setting the meter for a predetermined quantity using electromagnetic, electric or electronic means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F15/00Details of, or accessories for, apparatus of groups G01F1/00 - G01F13/00 insofar as such details or appliances are not adapted to particular types of such apparatus
    • G01F15/06Indicating or recording devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • G01F23/20Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measurement of weight, e.g. to determine the level of stored liquefied gas
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01FMEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • G01F23/80Arrangements for signal processing
    • G01F23/802Particular electronic circuits for digital processing equipment
    • G01F23/804Particular electronic circuits for digital processing equipment containing circuits handling parameters other than liquid level
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/028Modular arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/143Quality control, feedback systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/143Quality control, feedback systems
    • B01L2200/147Employing temperature sensors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/02Identification, exchange or storage of information
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0663Whole sensors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes

Abstract

There is provided a plate specifically a multi-well plate equipped with a mechanism to facilitate determination of the amount of a fluid added to or removed from a well in the plate. Specifically it foresees a balance integrated in the frame of the plate and capable of determining the difference in mass before and after filling the wells. Other embodiments foresee also a heating and cooling device to be associated with the plate and the plate to have removable wells. Other embodiments are also described.
PCT/IB2014/066178 2013-11-19 2014-11-19 Multi-well plates and methods of use thereof WO2015075653A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CN201480063117.2A CN105899294B (en) 2013-11-19 2014-11-19 Porous plate and its application method
EP14830870.3A EP3071332A2 (en) 2013-11-19 2014-11-19 Multi-well plates and methods of use thereof
CA2931068A CA2931068C (en) 2013-11-19 2014-11-19 Multi-well plates and methods of use thereof
JP2016553758A JP6553071B2 (en) 2013-11-19 2014-11-19 Multi-well plate and method of using the same
US15/157,428 US9827566B2 (en) 2013-11-19 2016-05-18 Multi-well plates and methods of use thereof
US15/795,294 US10758907B2 (en) 2013-11-19 2017-10-27 Multi-well plates and methods of use thereof

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201361905865P 2013-11-19 2013-11-19
US61/905,865 2013-11-19
US201461929086P 2014-01-19 2014-01-19
US61/929,086 2014-01-19
US201461949272P 2014-03-07 2014-03-07
US61/949,272 2014-03-07

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US15/157,428 Continuation-In-Part US9827566B2 (en) 2013-11-19 2016-05-18 Multi-well plates and methods of use thereof

Publications (2)

Publication Number Publication Date
WO2015075653A2 WO2015075653A2 (en) 2015-05-28
WO2015075653A3 true WO2015075653A3 (en) 2015-09-17

Family

ID=52424053

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2014/066178 WO2015075653A2 (en) 2013-11-19 2014-11-19 Multi-well plates and methods of use thereof

Country Status (5)

Country Link
EP (1) EP3071332A2 (en)
JP (1) JP6553071B2 (en)
CN (1) CN105899294B (en)
CA (1) CA2931068C (en)
WO (1) WO2015075653A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3199241A1 (en) 2016-01-27 2017-08-02 Genomica S.A.U. Multi-well test plate assembly and method of preparing a test plate for analysis
JP6799851B2 (en) * 2016-11-30 2020-12-16 国立大学法人東海国立大学機構 Sample processing method and sample processing kit
WO2021126420A1 (en) * 2019-12-16 2021-06-24 Siemens Healthcare Diagnostics Inc. Tube frame apparatus, tube frame assemblies, and methods of holding tubes
EP4085258A4 (en) * 2019-12-31 2023-06-14 Anatolia Tani Ve Biyoteknoloji Urunleri Arastirma Gelistirme Sanayi Ve Ticaret Anonim Sirketi A reactive cartridge carrying system

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1477226A1 (en) * 2003-05-13 2004-11-17 The Automation Partnership (Cambridge) Limited Test tube for storing fluid
US20060213964A1 (en) * 2005-03-24 2006-09-28 Varian, Inc. Sample identification utilizing RFID tags
US20080031774A1 (en) * 2006-03-13 2008-02-07 Sage Science, Inc. Apparatus for Guiding Sample and Reagent Manipulations and Receptacles for Holding Same
EP2623204A1 (en) * 2012-02-03 2013-08-07 F. Hoffmann-La Roche AG Sample handling system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL148664A0 (en) 2002-03-13 2002-09-12 Yeda Res & Dev Auto-focusing method and device
US7938032B2 (en) * 2008-10-30 2011-05-10 Agilent Technologies, Inc. Dissolution testing with in-situ gravimetric volume measurement
FI20095064A0 (en) * 2009-01-26 2009-01-26 Wallac Oy Apparatus and method for controlling the measuring head of an optical measuring instrument

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1477226A1 (en) * 2003-05-13 2004-11-17 The Automation Partnership (Cambridge) Limited Test tube for storing fluid
US20060213964A1 (en) * 2005-03-24 2006-09-28 Varian, Inc. Sample identification utilizing RFID tags
US20080031774A1 (en) * 2006-03-13 2008-02-07 Sage Science, Inc. Apparatus for Guiding Sample and Reagent Manipulations and Receptacles for Holding Same
EP2623204A1 (en) * 2012-02-03 2013-08-07 F. Hoffmann-La Roche AG Sample handling system

Also Published As

Publication number Publication date
JP2016538573A (en) 2016-12-08
CA2931068A1 (en) 2015-05-28
WO2015075653A2 (en) 2015-05-28
JP6553071B2 (en) 2019-07-31
CN105899294A (en) 2016-08-24
CN105899294B (en) 2019-08-16
EP3071332A2 (en) 2016-09-28
CA2931068C (en) 2020-10-27

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