WO2003001178A2 - Configurable dynamic three dimensional array - Google Patents
Configurable dynamic three dimensional array Download PDFInfo
- Publication number
- WO2003001178A2 WO2003001178A2 PCT/US2002/011586 US0211586W WO03001178A2 WO 2003001178 A2 WO2003001178 A2 WO 2003001178A2 US 0211586 W US0211586 W US 0211586W WO 03001178 A2 WO03001178 A2 WO 03001178A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optical
- probes
- probe
- light
- traps
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00283—Reactor vessels with top opening
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00436—Maskless processes
- B01J2219/00441—Maskless processes using lasers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00599—Solution-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00664—Three-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00709—Type of synthesis
- B01J2219/00711—Light-directed synthesis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0668—Trapping microscopic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0877—Flow chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0454—Moving fluids with specific forces or mechanical means specific forces radiation pressure, optical tweezers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/08—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Definitions
- the optical bottle differs from an optical vortex in that it has a zero electric field only at the focus and a non-zero electric field in all other directions surrounding the focus, at an end of the vortex.
- An optical bottle may be useful in trapping atoms and nanoclusters which may be too small or too absorptive to trap with an optical vortex or optical tweezers.
- the optical rotator is a recently described optical tool which provides a pattern of spiral arms which trap objects. Changing the pattern causes the trapped objects to rotate.
- FIG. 5 A illustrates a first operative movement of probes.
- FIG. 6B illustrates an inverted microscope to which the compact system of Fig. 6A attaches.
- Preferred dynamic optical elements include phase-only spatial light modulators such as the "PAL-SLM series X7665", manufactured by Hamamatsu, of Japan or the "SLM 512N15' and SLM 512SA7,” both manufactured by Boulder Nonlinear Systems of Layafette Colorado. These phase patterning optical elements are computer controlled to generate the beamlets 2000-2004 (FIG. 1) by a hologram encoded in the medium which can be varied to generate the beamlets and select the form of the beamlets.
- phase-only spatial light modulators such as the "PAL-SLM series X7665", manufactured by Hamamatsu, of Japan or the "SLM 512N15' and SLM 512SA7,” both manufactured by Boulder Nonlinear Systems of Layafette Colorado.
- These phase patterning optical elements are computer controlled to generate the beamlets 2000-2004 (FIG. 1) by a hologram encoded in the medium which can be varied to generate the beamlets and select the form of the beamlets.
- the probes can be added to the vessel 10 in a sequential order.
- identity of a probe is known by its load order or a probe's identify can be known on the basis of the time that the probe is added.
- the probes having binding or reactivity characteristics that differ from one another can be segregated to different predetermined locations, based on the difference in properties. The probes are then selected on the basis of their location within the vessel. As seen in FIG.
- the sequence may continue passing the probes from the second set of predetermined positions P2 to a third set of predetermined positions P3, from the third set of positions P3 to a fourth set of predetermined positions P4, and from the fourth set of predetermined positions P4 to a fifth set of predetermined positions P5 by the rotation of the phase patterning optical element to align the appropriate region 42-46 corresponding to the desired position P1-P5.
- the time interval between the termination of one set of optical traps and the generation of the next should be of a duration to ensure that the probes are transferred to the next set of optical traps before they drift away.
- a dichroic mirror beam splitter 58 Interposed in the third light channel between the second light channel and the back aperture 57 of the focusing lens is a dichroic mirror beam splitter 58.
- Other components within the compact system for forming the optical traps 50 include a first mirror Ml, which reflects the beamlets emanating from the phase patterning optical element through the first light channel, a first set of transfer optics TOl disposed within the first light channel, aligned to receive the beamlets reflected by the first mirror Ml, a second set of transfer optics TO2 disposed within the first light channel, aligned to receive the beamlets passing through the first set of transfer lenses TOl, and a second mirror M2, positioned at the intersection of the first light channel and the second light channel, aligned to reflect beamlets passing through the second set of transfer optics TO2 and through the third light channel 55 a.
- FIG. 6B Shown in FIG. 6B is an elevational view of a Nixon TE 200 series microscope into which the compact system for forming the optical traps 50 has been mounted, generally designated 60.
- the nosepiece 54 with the attached a housing 52 fits directly into the microscope via the mount (not shown) for the nosepiece 54a and 54b.
- the housing and its contents and attached optical element 51 are secured to the nosepiece 54a and 54b require few or no alterations or modifications to the remainder of the microscope.
- an illumination source 61 may be provided above the objective lens 56.
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ530239A NZ530239A (en) | 2001-06-20 | 2002-04-12 | Configurable dynamic three dimensional array |
CA002451222A CA2451222A1 (en) | 2001-06-20 | 2002-04-12 | Configurable dynamic three dimensional array |
EP02731351A EP1412519A4 (en) | 2001-06-20 | 2002-04-12 | Configurable dynamic three dimensional array |
JP2003507524A JP4199107B2 (en) | 2001-06-20 | 2002-04-12 | Arrayable dynamic 3D array |
US10/735,395 US20040180363A1 (en) | 2002-04-12 | 2003-12-12 | Configurable dynamic three dimensional array |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88680201A | 2001-06-20 | 2001-06-20 | |
US09/886,802 | 2001-06-20 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/735,395 Continuation-In-Part US20040180363A1 (en) | 2002-04-12 | 2003-12-12 | Configurable dynamic three dimensional array |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003001178A2 true WO2003001178A2 (en) | 2003-01-03 |
WO2003001178A3 WO2003001178A3 (en) | 2003-02-27 |
Family
ID=25389806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/011586 WO2003001178A2 (en) | 2001-06-20 | 2002-04-12 | Configurable dynamic three dimensional array |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1412519A4 (en) |
JP (1) | JP4199107B2 (en) |
CN (2) | CN1545561A (en) |
CA (1) | CA2451222A1 (en) |
HK (1) | HK1078933A1 (en) |
NZ (1) | NZ530239A (en) |
WO (1) | WO2003001178A2 (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1469483A2 (en) | 2003-04-16 | 2004-10-20 | Shamci Dr. Monajemsbashi | Sample for manipulation by an optical tweezers, and a method and device to generate optically induced forces |
EP1687663A2 (en) * | 2003-10-28 | 2006-08-09 | Arryx, Inc. | System and method for manipulating and processing materials using holographic optical trapping |
EP1745530A2 (en) * | 2004-03-17 | 2007-01-24 | Arryx, Inc. | System and method for manipulating and processing materials using holographic optical trapping |
US7525088B2 (en) | 2004-07-23 | 2009-04-28 | The Science And Technology Facilities Council | Optically controllable device |
EP2150806A1 (en) * | 2007-05-10 | 2010-02-10 | Pacific Biosciences of California, Inc. | Methods and systems for analyzing fluorescent materials with reduced autofluorescence |
US8169600B2 (en) | 2006-09-15 | 2012-05-01 | Arryx, Inc. | Surface mapping by optical manipulation of particles in relation to a functionalized surface |
KR20150023810A (en) * | 2012-06-18 | 2015-03-05 | 존 마일즈 브루배춰 | Microorganism evaluation system |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101795744A (en) * | 2007-09-11 | 2010-08-04 | 阿尔利克斯公司 | Binding method and apparatus for sorting objects |
US7998676B2 (en) * | 2007-09-13 | 2011-08-16 | Arryx, Inc. | Methods and apparatuses for sorting objects in forensic DNA analysis and medical diagnostics |
PL2280875T3 (en) * | 2008-04-23 | 2012-10-31 | Signode Int Ip Holdings Llc | Strapping device with a gear system device |
CN109239937A (en) * | 2018-09-15 | 2019-01-18 | 天津大学 | A kind of optical tweezer automation control device |
CN113053556A (en) * | 2021-03-10 | 2021-06-29 | 暨南大学 | Biological micromotor array with reconfigurability and application thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5776674A (en) * | 1995-06-05 | 1998-07-07 | Seq, Ltd | Chemical biochemical and biological processing in thin films |
US6055106A (en) * | 1998-02-03 | 2000-04-25 | Arch Development Corporation | Apparatus for applying optical gradient forces |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3102523B2 (en) * | 1992-10-12 | 2000-10-23 | 日本電信電話株式会社 | Fine particle array control method |
CN1079158C (en) * | 1996-11-26 | 2002-02-13 | 中国科学院上海光学精密机械研究所 | Optical suspension measuring system |
-
2002
- 2002-04-12 WO PCT/US2002/011586 patent/WO2003001178A2/en active Application Filing
- 2002-04-12 NZ NZ530239A patent/NZ530239A/en not_active Application Discontinuation
- 2002-04-12 CN CNA028162889A patent/CN1545561A/en active Pending
- 2002-04-12 CA CA002451222A patent/CA2451222A1/en not_active Abandoned
- 2002-04-12 CN CN 200510081431 patent/CN1715918B/en not_active Expired - Fee Related
- 2002-04-12 EP EP02731351A patent/EP1412519A4/en not_active Withdrawn
- 2002-04-12 JP JP2003507524A patent/JP4199107B2/en not_active Expired - Fee Related
-
2006
- 2006-01-13 HK HK06100648.0A patent/HK1078933A1/en not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5776674A (en) * | 1995-06-05 | 1998-07-07 | Seq, Ltd | Chemical biochemical and biological processing in thin films |
US6055106A (en) * | 1998-02-03 | 2000-04-25 | Arch Development Corporation | Apparatus for applying optical gradient forces |
Non-Patent Citations (1)
Title |
---|
See also references of EP1412519A2 * |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1469483A2 (en) | 2003-04-16 | 2004-10-20 | Shamci Dr. Monajemsbashi | Sample for manipulation by an optical tweezers, and a method and device to generate optically induced forces |
EP1469483A3 (en) * | 2003-04-16 | 2009-06-03 | Monajemsbashi, Shamci, Dr. | Sample for manipulation by an optical tweezers, and a method and device to generate optically induced forces |
JP2007510160A (en) * | 2003-10-28 | 2007-04-19 | アリックス インコーポレイテッド | System and method for manipulating and processing materials using holographic light trapping |
EP1687663A2 (en) * | 2003-10-28 | 2006-08-09 | Arryx, Inc. | System and method for manipulating and processing materials using holographic optical trapping |
EP1687663A4 (en) * | 2003-10-28 | 2010-03-31 | Arryx Inc | System and method for manipulating and processing materials using holographic optical trapping |
EP1745530A2 (en) * | 2004-03-17 | 2007-01-24 | Arryx, Inc. | System and method for manipulating and processing materials using holographic optical trapping |
JP2007537885A (en) * | 2004-03-17 | 2007-12-27 | アリックス インコーポレイテッド | System and method for manipulating and processing materials using holographic light trapping |
EP1745530A4 (en) * | 2004-03-17 | 2009-08-05 | Arryx Inc | System and method for manipulating and processing materials using holographic optical trapping |
US7525088B2 (en) | 2004-07-23 | 2009-04-28 | The Science And Technology Facilities Council | Optically controllable device |
US8169600B2 (en) | 2006-09-15 | 2012-05-01 | Arryx, Inc. | Surface mapping by optical manipulation of particles in relation to a functionalized surface |
EP2150806A1 (en) * | 2007-05-10 | 2010-02-10 | Pacific Biosciences of California, Inc. | Methods and systems for analyzing fluorescent materials with reduced autofluorescence |
EP2150806A4 (en) * | 2007-05-10 | 2013-01-02 | Pacific Biosciences California | Methods and systems for analyzing fluorescent materials with reduced autofluorescence |
KR20150023810A (en) * | 2012-06-18 | 2015-03-05 | 존 마일즈 브루배춰 | Microorganism evaluation system |
KR102102285B1 (en) | 2012-06-18 | 2020-04-20 | 존 마일즈 브루배춰 | Microorganism evaluation system |
Also Published As
Publication number | Publication date |
---|---|
JP2004532991A (en) | 2004-10-28 |
JP4199107B2 (en) | 2008-12-17 |
EP1412519A4 (en) | 2007-07-04 |
EP1412519A2 (en) | 2004-04-28 |
CN1715918A (en) | 2006-01-04 |
WO2003001178A3 (en) | 2003-02-27 |
CN1715918B (en) | 2010-05-12 |
CN1545561A (en) | 2004-11-10 |
CA2451222A1 (en) | 2003-01-03 |
HK1078933A1 (en) | 2006-03-24 |
NZ530239A (en) | 2006-08-31 |
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