WO2002076282A3 - Method for quantitative analysis of blood vessel structure - Google Patents

Method for quantitative analysis of blood vessel structure Download PDF

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Publication number
WO2002076282A3
WO2002076282A3 PCT/US2002/000529 US0200529W WO02076282A3 WO 2002076282 A3 WO2002076282 A3 WO 2002076282A3 US 0200529 W US0200529 W US 0200529W WO 02076282 A3 WO02076282 A3 WO 02076282A3
Authority
WO
WIPO (PCT)
Prior art keywords
measurement
results
analysis
blood vessel
accurate
Prior art date
Application number
PCT/US2002/000529
Other languages
French (fr)
Other versions
WO2002076282A2 (en
Inventor
Peter C Johnson
Sujal Shah
Michael G Fuhrman
Othman A Abdul-Karim
Original Assignee
Tissueinformatics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tissueinformatics Inc filed Critical Tissueinformatics Inc
Publication of WO2002076282A2 publication Critical patent/WO2002076282A2/en
Publication of WO2002076282A3 publication Critical patent/WO2002076282A3/en

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Classifications

    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/12Edge-based segmentation
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10056Microscopic image
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30101Blood vessel; Artery; Vein; Vascular

Abstract

We disclose quantitative geometrical analysis enabling the measurement of several features of images of tissues including perimeter, area, and other metrics. Automation of features extraction creates a high throughput capability that enables analysis of serial sections for more accurate measurement of tissue dimensions. Measurement results are input into a relational database where they can be statistically analyzed and compared across studies. As part of the integrated process, results are also imprinted on the images themselves to facilitate auditing of the results. The analysis is fast, repeatable and accurate while allowing the pathologist to control the measurement process.
PCT/US2002/000529 2001-01-05 2002-01-07 Method for quantitative analysis of blood vessel structure WO2002076282A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25982201P 2001-01-05 2001-01-05
US60/259,822 2001-01-05

Publications (2)

Publication Number Publication Date
WO2002076282A2 WO2002076282A2 (en) 2002-10-03
WO2002076282A3 true WO2002076282A3 (en) 2003-11-13

Family

ID=22986538

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/000529 WO2002076282A2 (en) 2001-01-05 2002-01-07 Method for quantitative analysis of blood vessel structure

Country Status (1)

Country Link
WO (1) WO2002076282A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7116810B2 (en) * 2002-11-27 2006-10-03 General Electric Company Method and system for airway measurement
AU2015372563A1 (en) 2014-12-29 2017-06-22 F. Hoffmann-La Roche Ag Vessel analysis in multiplexed images
US10943350B2 (en) 2015-02-25 2021-03-09 London Health Science Center Research Inc. Automated segmentation of histological sections for vasculature quantification
FR3122077B1 (en) * 2021-04-22 2023-03-31 Biocellvia System and method for morphometric analysis of organ vasculature

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5784162A (en) * 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US6101265A (en) * 1996-08-23 2000-08-08 Bacus Research Laboratories, Inc. Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope
US6137899A (en) * 1994-09-20 2000-10-24 Tri Path Imaging, Inc. Apparatus for the identification of free-lying cells
US6181811B1 (en) * 1998-01-13 2001-01-30 Neopath, Inc. Method and apparatus for optimizing biological and cytological specimen screening and diagnosis
US6246785B1 (en) * 1996-04-27 2001-06-12 Roche Diagnostics Gmbh Automated, microscope-assisted examination process of tissue or bodily fluid samples
US6404906B2 (en) * 1997-03-03 2002-06-11 Bacus Research Laboratories,Inc. Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope
US6415046B1 (en) * 1999-10-07 2002-07-02 Edmund Kenneth Kerut, Sr. Method and apparatus for the early detection of tissue pathology using wavelet transformation
US6463438B1 (en) * 1994-06-03 2002-10-08 Urocor, Inc. Neural network for cell image analysis for identification of abnormal cells

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5784162A (en) * 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US6463438B1 (en) * 1994-06-03 2002-10-08 Urocor, Inc. Neural network for cell image analysis for identification of abnormal cells
US6137899A (en) * 1994-09-20 2000-10-24 Tri Path Imaging, Inc. Apparatus for the identification of free-lying cells
US6246785B1 (en) * 1996-04-27 2001-06-12 Roche Diagnostics Gmbh Automated, microscope-assisted examination process of tissue or bodily fluid samples
US6101265A (en) * 1996-08-23 2000-08-08 Bacus Research Laboratories, Inc. Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope
US6404906B2 (en) * 1997-03-03 2002-06-11 Bacus Research Laboratories,Inc. Method and apparatus for acquiring and reconstructing magnified specimen images from a computer-controlled microscope
US6181811B1 (en) * 1998-01-13 2001-01-30 Neopath, Inc. Method and apparatus for optimizing biological and cytological specimen screening and diagnosis
US6415046B1 (en) * 1999-10-07 2002-07-02 Edmund Kenneth Kerut, Sr. Method and apparatus for the early detection of tissue pathology using wavelet transformation

Also Published As

Publication number Publication date
WO2002076282A2 (en) 2002-10-03

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