She is the show's longest-running female cast-member.
But Coronation Street actress Eileen Derbyshire, 85, is set to quit the ITV soap after taking an extended 12-month break.
According to The Sun, the veteran performer - who has played Emily Bishop in the drama since 1961 - will retire from the cobbles after nearly six decades, following a prolonged sabbatical that she took late last year.
A source said: "Eileen has been off for a long time, and there is no expectation that she will be back. All of her cast mates have accepted she won't be returning.
"She's 85 and has been out of the show for a year, so she probably would have found it tough to get back into the fast pace of filming."
Additionally, the source says Eileen - who was honoured with an MBE for services to drama in 2010 - will focus on quality time with her family instead.
Her departure will be the latest in a long line of emotional exits for the show's most famous stars, who grace TV screens up to five times a week.
In recent years, Michelle Keegan quit to embark on new career opportunities such as Our Girl, while Anne Kirkbride - who played Dierdre Barlow - died from breast cancer in January 2015.
Meanwhile, Jean Alexander - best known to British television viewers as Hilda Ogden - died in October.
Most Read
Similarly, Corrie actor Robert Vaughn, most famous as Napoleon Solo in Man From Uncle, died on 11 November 2016 aged 83.
Vaughn, who also starred in the Magnificent Seven and Hustle, is survived by wife Linda, son Cassidy and daughter Caitlin.
His manager Matthew Sullivan confirmed to Deadline that that he had passed away following a short battle with acute leukemia.
"Mr Vaughn passed away with him family around him," he added.