Introduction. Human leukocyte antigens (HLA) are genes in major histocompatibility complexes (MHC) that help code for proteins that differentiate between self and non-self. They play a significant role in disease and immune defense. They are beneficial to the immune system but can also have detrimental effects.
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The human leukocyte antigen (HLA) system or complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for regulation of the ...
The human leukocyte antigen (HLA) system (the major histocompatibility complex [MHC] in humans) is an important part of the immune system and is controlled ...
The IPD-IMGT/HLA Database provides a specialist database for sequences of the human major histocompatibility complex (MHC) and includes the official sequences ...
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Jul 19, 2023 · We tested for association of five HLA loci with disease course and identified a strong association between HLA-B*15:01 and asymptomatic infection.
The function of HLA-encoded class I and class II molecules is to bind peptide antigens and display them for recognition by antigen-specific T lymphocytes.
Nov 9, 2021 · HLA testing is used to match organ and tissue transplant recipients with compatible donors. Different kinds of transplants require different ...
Mar 23, 2022 · The HLA-B gene provides instructions for making a protein that plays a critical role in the immune system. Learn about this gene and related ...
Sep 8, 2023 · The HLA region lies on the short arm of chromosome six at position 6p21.3. The classical MHC spans 3.6 megabases (Mb) and comprises more than ...
