The present invention provides compounds, methods and systems for sequencing nucleic acid using single molecule detection. Using labeled NPs that exhibit charge-switching behavior, single-molecule DNA sequencing in a microchannel sorting system is realized. In operation, sequencing products are detected...http://www.google.co.uk/patents/US8148516?utm_source=gb-gplus-sharePatent US8148516 - Flowcell systems for single molecule detection
