Blockade of mismatch repair in a plant can lead to hypermutation and a new genotype and/or phenotype. One approach used to generate hypermutable plants is through the expression of dominant negative alleles of mismatch repair genes in transgenic plants or derived cells. By introducing these genes into...http://www.google.co.uk/patents/US7704689?utm_source=gb-gplus-sharePatent US7704689 - Method for generating hypermutable plants
