Novel compounds, pharmaceutical compositions and methods are disclosed for producing local anesthesia of long-duration. The compounds of this invention are multibinding compounds that comprise from 2 to 10 ligands covalently attached to a linker or linkers, each ligand being capable of binding to a ligand...http://www.google.co.uk/patents/US6495681?utm_source=gb-gplus-sharePatent US6495681 - Local anesthetic compounds and uses