A micro-catheter system utilizing a microjoule pulsed electrical discharge between first and second electrodes in a recessed lumen at the catheter working end for creating a cavitating volume of electrolytic fluid composition including a pharmacologic agent. The expansion and collapse of media at a high...http://www.google.co.uk/patents/US20010037106?utm_source=gb-gplus-sharePatent US20010037106 - Medical instrument working end creating very high pressure gradients