The optimal location for delivering pacing pulses to a given cardiac chamber (such as the left ventricle) is determined by identifying the last electrically or mechanically activated site within the chamber. For example, the last site within the left ventricular myocardium to depolarize during an intrinsic...http://www.google.co.uk/patents/US20050149138?utm_source=gb-gplus-sharePatent US20050149138 - System and method for determining optimal pacing sites based on myocardial activation times