WO2012027617A3 - Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (mals) instrument - Google Patents

Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (mals) instrument Download PDF

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Publication number
WO2012027617A3
WO2012027617A3 PCT/US2011/049236 US2011049236W WO2012027617A3 WO 2012027617 A3 WO2012027617 A3 WO 2012027617A3 US 2011049236 W US2011049236 W US 2011049236W WO 2012027617 A3 WO2012027617 A3 WO 2012027617A3
Authority
WO
WIPO (PCT)
Prior art keywords
water
particle
bacteria
mals
instrument
Prior art date
Application number
PCT/US2011/049236
Other languages
French (fr)
Other versions
WO2012027617A2 (en
Inventor
John A. Adams
Original Assignee
Jmar Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jmar Llc filed Critical Jmar Llc
Priority to EP11820685.3A priority Critical patent/EP2609414A2/en
Publication of WO2012027617A2 publication Critical patent/WO2012027617A2/en
Publication of WO2012027617A3 publication Critical patent/WO2012027617A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1468—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Electro-optical investigation, e.g. flow cytometers with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/18—Water
    • G01N33/1893—Water using flow cells
    • G01N2015/019—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1497—Particle shape

Abstract

A particle detection system uses a camera to produce a picture based on the scattered light generated by a particle in a liquid medium, when a laser beam is incident on the particle. These pictures are then automatically analyzed through the use of a processing system (e.g., a computer). The processing system is configured to record the forward scattering intensity (e.g., amplitude) and the picture of the scattered light rays to generate a classification of the particle causing the scattering. Count rate and trends of the classified particles are monitored to detect a change that is representative of the overall health safety of the water or by knowing the levels of bacteria in process water, such as Reverse Osmosis (RO) feed water, reject brine, and product water, the operator may better monitor the life and condition of the RO membrane.
PCT/US2011/049236 2010-08-25 2011-08-25 Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (mals) instrument WO2012027617A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP11820685.3A EP2609414A2 (en) 2010-08-25 2011-08-25 Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (mals) instrument

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/868,654 2010-08-25
US12/868,654 US8243272B2 (en) 2005-09-19 2010-08-25 Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (MALS) instrument

Publications (2)

Publication Number Publication Date
WO2012027617A2 WO2012027617A2 (en) 2012-03-01
WO2012027617A3 true WO2012027617A3 (en) 2012-05-24

Family

ID=45724075

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/049236 WO2012027617A2 (en) 2010-08-25 2011-08-25 Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (mals) instrument

Country Status (3)

Country Link
US (1) US8243272B2 (en)
EP (1) EP2609414A2 (en)
WO (1) WO2012027617A2 (en)

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TW201317353A (en) * 2011-07-13 2013-05-01 Dow Agrosciences Llc Stacked herbicide tolerance event 8264.42.32.1, related transgenic soybean lines, and detection thereof
JP6289450B2 (en) 2012-05-09 2018-03-07 シーゲイト テクノロジー エルエルシーＳｅａｇａｔｅ Ｔｅｃｈｎｏｌｏｇｙ ＬＬＣ Surface feature mapping
WO2013185621A1 (en) * 2012-06-14 2013-12-19 南京拓鉒医药科技有限公司 Endotoxin detection systems and detection methods thereof
CN102692396B (en) * 2012-06-14 2014-04-02 南京中医药大学 Endotoxin detection system and quantitative detection method thereof
US9212900B2 (en) 2012-08-11 2015-12-15 Seagate Technology Llc Surface features characterization
US9297759B2 (en) 2012-10-05 2016-03-29 Seagate Technology Llc Classification of surface features using fluorescence
US9297751B2 (en) 2012-10-05 2016-03-29 Seagate Technology Llc Chemical characterization of surface features
US10024790B2 (en) 2012-10-05 2018-07-17 Seagate Technology Llc Imaging a transparent article
US9377394B2 (en) 2012-10-16 2016-06-28 Seagate Technology Llc Distinguishing foreign surface features from native surface features
US9217714B2 (en) 2012-12-06 2015-12-22 Seagate Technology Llc Reflective surfaces for surface features of an article
AU2014223163A1 (en) * 2013-02-28 2015-08-20 Olive Medical Corporation Videostroboscopy of vocal chords with CMOS sensors
BR112015026037A2 (en) * 2013-04-19 2017-07-25 Koninklijke Philips Nv optical system for determining a feature as a function of time of at least a part of a net volume, and method of determining a feature as a function of time of a net volume comprising a plurality of objects
US9372143B2 (en) * 2013-05-15 2016-06-21 Captl Llc Scanning image flow cytometer
US9217715B2 (en) 2013-05-30 2015-12-22 Seagate Technology Llc Apparatuses and methods for magnetic features of articles
US9513215B2 (en) 2013-05-30 2016-12-06 Seagate Technology Llc Surface features by azimuthal angle
US9201019B2 (en) 2013-05-30 2015-12-01 Seagate Technology Llc Article edge inspection
SE537489C2 (en) * 2014-02-03 2015-05-19 Method and device for online water quality monitoring
US10900885B2 (en) 2014-12-19 2021-01-26 Captl Llc Flow cytometry using hydrodynamically planar flow
JP6557022B2 (en) * 2015-02-18 2019-08-07 アズビル株式会社 Particle detector
JP6438319B2 (en) * 2015-02-18 2018-12-12 アズビル株式会社 Particle detector
US10036698B2 (en) 2015-06-19 2018-07-31 Captl Llc Time-sequential cytometry
WO2017004236A1 (en) * 2015-06-29 2017-01-05 The Arizona Board Of Regents On Behalf Of The University Of Arizona Optical device for in-line and real-time monitoring of microorganisms
US10444137B2 (en) * 2018-01-23 2019-10-15 Cbrn International, Ltd. Bioaerosol detector having safeguards
TWI771806B (en) * 2020-11-18 2022-07-21 財團法人工業技術研究院 Particle-sensing device
US11275014B1 (en) * 2021-05-03 2022-03-15 Roy Olson Particle characteristic measurement apparatus

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US20080172185A1 (en) * 2007-01-17 2008-07-17 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Automatic classifying method, device and system for flow cytometry
WO2009093017A1 (en) * 2008-01-25 2009-07-30 The Secretary Of State For Defence Fluid-borne particle detector
US20090316138A1 (en) * 2008-04-25 2009-12-24 Herzog William D Method and instrumentation for determining a physical property of a particle
US20100007505A1 (en) * 2005-09-19 2010-01-14 Jmar Llc Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (mals) instrument
US20100108910A1 (en) * 2005-07-15 2010-05-06 Michael Morrell Pathogen and particle detector system and method

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US20100007505A1 (en) * 2005-09-19 2010-01-14 Jmar Llc Systems and methods for detecting normal levels of bacteria in water using a multiple angle light scattering (mals) instrument
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WO2009093017A1 (en) * 2008-01-25 2009-07-30 The Secretary Of State For Defence Fluid-borne particle detector
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Also Published As

Publication number Publication date
US8243272B2 (en) 2012-08-14
WO2012027617A2 (en) 2012-03-01
US20110066382A1 (en) 2011-03-17
EP2609414A2 (en) 2013-07-03

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