WO2009131837A3 - Systems, methods and compositions for optical stimulation of target cells - Google Patents
Systems, methods and compositions for optical stimulation of target cells Download PDFInfo
- Publication number
- WO2009131837A3 WO2009131837A3 PCT/US2009/039949 US2009039949W WO2009131837A3 WO 2009131837 A3 WO2009131837 A3 WO 2009131837A3 US 2009039949 W US2009039949 W US 2009039949W WO 2009131837 A3 WO2009131837 A3 WO 2009131837A3
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- WIPO (PCT)
- Prior art keywords
- ion channel
- light
- systems
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- A—HUMAN NECESSITIES
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- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0058—Nucleic acids adapted for tissue specific expression, e.g. having tissue specific promoters as part of a contruct
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- A61K48/0083—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the administration regime
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- C07K14/405—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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Abstract
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09735499.7T ES2608498T3 (en) | 2008-04-23 | 2009-04-08 | Systems, methods and compositions for optical stimulation of target cells |
MX2010011657A MX2010011657A (en) | 2008-04-23 | 2009-04-08 | Systems, methods and compositions for optical stimulation of target cells. |
BRPI0911448-3A BRPI0911448A2 (en) | 2008-04-23 | 2009-04-08 | systems, methods and compositions for optical simulation of target cells |
EP09735499.7A EP2281039B1 (en) | 2008-04-23 | 2009-04-08 | Systems, methods and compositions for optical stimulation of target cells |
CA2722278A CA2722278C (en) | 2008-04-23 | 2009-04-08 | Systems, methods and compositions for optical stimulation of target cells |
EP16189132.0A EP3165534B1 (en) | 2008-04-23 | 2009-04-08 | Systems, methods and compositions for optical stimulation of target cells |
JP2011506348A JP5801188B2 (en) | 2008-04-23 | 2009-04-08 | Systems, methods, and compositions for photostimulating target cells |
AU2009238467A AU2009238467B2 (en) | 2008-04-23 | 2009-04-08 | Systems, methods and compositions for optical stimulation of target cells |
US12/988,567 US8603790B2 (en) | 2008-04-23 | 2009-04-08 | Systems, methods and compositions for optical stimulation of target cells |
IL208877A IL208877A0 (en) | 2008-04-23 | 2010-10-21 | Systems, methods and compostions for optical stimlation of target cells |
US13/718,243 US8815582B2 (en) | 2008-04-23 | 2012-12-18 | Mammalian cell expressing Volvox carteri light-activated ion channel protein (VChR1) |
US14/301,718 US9249200B2 (en) | 2008-04-23 | 2014-06-11 | Expression vector comprising a nucleotide sequence encoding a Volvox carteri light-activated ion channel protein (VChR1) and implantable device thereof |
US14/694,845 US9394347B2 (en) | 2008-04-23 | 2015-04-23 | Methods for treating parkinson's disease by optically stimulating target cells |
AU2015207841A AU2015207841B2 (en) | 2008-04-23 | 2015-07-28 | Systems, methods and compositions for optical stimulation of target cells |
US15/194,381 US9878176B2 (en) | 2008-04-23 | 2016-06-27 | System utilizing Volvox carteri light-activated ion channel protein (VChR1) for optical stimulation of target cells |
US15/861,433 US10350430B2 (en) | 2008-04-23 | 2018-01-03 | System comprising a nucleotide sequence encoding a volvox carteri light-activated ion channel protein (VCHR1) |
US16/415,567 US20190336784A1 (en) | 2008-04-23 | 2019-05-17 | Systems, methods and compositions for optical stimulation of target cells |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4721908P | 2008-04-23 | 2008-04-23 | |
US61/047,219 | 2008-04-23 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/988,567 A-371-Of-International US8603790B2 (en) | 2008-04-23 | 2009-04-08 | Systems, methods and compositions for optical stimulation of target cells |
US13/718,243 Division US8815582B2 (en) | 2008-04-23 | 2012-12-18 | Mammalian cell expressing Volvox carteri light-activated ion channel protein (VChR1) |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009131837A2 WO2009131837A2 (en) | 2009-10-29 |
WO2009131837A3 true WO2009131837A3 (en) | 2010-01-07 |
Family
ID=41217365
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2009/039949 WO2009131837A2 (en) | 2008-04-23 | 2009-04-08 | Systems, methods and compositions for optical stimulation of target cells |
Country Status (14)
Country | Link |
---|---|
US (7) | US8603790B2 (en) |
EP (2) | EP2281039B1 (en) |
JP (2) | JP5801188B2 (en) |
KR (1) | KR20110005280A (en) |
AU (2) | AU2009238467B2 (en) |
BR (1) | BRPI0911448A2 (en) |
CA (1) | CA2722278C (en) |
ES (2) | ES2608498T3 (en) |
IL (1) | IL208877A0 (en) |
MX (1) | MX2010011657A (en) |
MY (1) | MY169771A (en) |
RU (1) | RU2010147661A (en) |
SG (1) | SG189813A1 (en) |
WO (1) | WO2009131837A2 (en) |
Cited By (1)
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CN108070615A (en) * | 2017-12-25 | 2018-05-25 | 深圳先进技术研究院 | A kind of carrier of regulation and control parathyroid gland PTH secretions and its application |
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US9274099B2 (en) | 2005-07-22 | 2016-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Screening test drugs to identify their effects on cell membrane voltage-gated ion channel |
US10052497B2 (en) | 2005-07-22 | 2018-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
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US20090093403A1 (en) | 2007-03-01 | 2009-04-09 | Feng Zhang | Systems, methods and compositions for optical stimulation of target cells |
US8926959B2 (en) * | 2005-07-22 | 2015-01-06 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
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WO2008086470A1 (en) | 2007-01-10 | 2008-07-17 | The Board Of Trustees Of The Leland Stanford Junior University | System for optical stimulation of target cells |
US8401609B2 (en) * | 2007-02-14 | 2013-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | System, method and applications involving identification of biological circuits such as neurological characteristics |
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MX2010012986A (en) * | 2008-05-29 | 2011-05-25 | Univ Leland Stanford Junior | Cell line, system and method for optical control of secondary messengers. |
BRPI0915583A2 (en) * | 2008-06-17 | 2016-01-26 | Univ Leland Stanford Junior | apparatus and methods for controlling cell development |
CA2728238C (en) | 2008-06-17 | 2019-03-12 | M. Bret Schneider | Methods, systems and devices for optical stimulation of target cells using an optical transmission element |
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NZ602416A (en) | 2008-11-14 | 2014-08-29 | Univ Leland Stanford Junior | Optically-based stimulation of target cells and modifications thereto |
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US20120245493A1 (en) * | 2011-03-21 | 2012-09-27 | Mishelevich David J | Ultrasound neuromodulation treatment of addiction |
SG183899A1 (en) | 2010-03-17 | 2012-10-30 | Univ Leland Stanford Junior | Light-sensitive ion-passing molecules |
US9207237B2 (en) | 2010-08-23 | 2015-12-08 | President And Fellows Of Harvard College | Systems, methods, and workflows for optogenetics analysis |
CN103168236B (en) | 2010-08-23 | 2016-01-20 | 哈佛大学管理委员会 | For the light genetics probe that membrane potential measures |
CN106422081B (en) | 2010-11-05 | 2019-06-21 | 斯坦福大学托管董事会 | The upper conversion of light for light genetic method |
EP3486253A1 (en) * | 2010-11-05 | 2019-05-22 | The Board of Trustees of The Leland Stanford Junior University | Light-activated chimeric opsins and methods of using the same |
CN106106368A (en) | 2010-11-05 | 2016-11-16 | 斯坦福大学托管董事会 | Optically-controlledCNS CNS dysfunction |
ES2684307T3 (en) * | 2010-11-05 | 2018-10-02 | The Board Of Trustees Of The Leland Stanford Junior University | Stabilized opsin-type proteins of staggered function and methods of use thereof |
EP3225108A1 (en) | 2010-11-05 | 2017-10-04 | The Board of Trustees of The Leland Stanford Junior University | Optogenetic control of reward-related behaviors |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108070615A (en) * | 2017-12-25 | 2018-05-25 | 深圳先进技术研究院 | A kind of carrier of regulation and control parathyroid gland PTH secretions and its application |
CN108070615B (en) * | 2017-12-25 | 2021-11-05 | 深圳先进技术研究院 | Vector for regulating and controlling secretion of parathyroid PTH and application thereof |
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