WO2009131323A3 - Hyaluronic acid bone-filling complex and fabrication method thereof - Google Patents

Hyaluronic acid bone-filling complex and fabrication method thereof Download PDF

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Publication number
WO2009131323A3
WO2009131323A3 PCT/KR2009/001862 KR2009001862W WO2009131323A3 WO 2009131323 A3 WO2009131323 A3 WO 2009131323A3 KR 2009001862 W KR2009001862 W KR 2009001862W WO 2009131323 A3 WO2009131323 A3 WO 2009131323A3
Authority
WO
WIPO (PCT)
Prior art keywords
hyaluronic acid
bone
filling
fabrication method
filling complex
Prior art date
Application number
PCT/KR2009/001862
Other languages
French (fr)
Korean (ko)
Other versions
WO2009131323A2 (en
Inventor
박광범
최석규
양동준
안현욱
한세광
염준석
박정규
오은주
신홍인
Original Assignee
주식회사 메가젠임플란트
포항공과대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 메가젠임플란트, 포항공과대학교 산학협력단 filed Critical 주식회사 메가젠임플란트
Publication of WO2009131323A2 publication Critical patent/WO2009131323A2/en
Publication of WO2009131323A3 publication Critical patent/WO2009131323A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Abstract

The present invention relates to a hyaluronic acid bone-filling complex and a fabrication method thereof. The hyaluronic acid bone-filling complex according to the present invention includes a matrix containing hyaluronic acid derivatives and MGSB filling the matrix, and thus it is capable of guiding regeneration of alveolar bone in an effective manner as compared with conventional bone-filling substitutes, and maximizing guiding of bone regeneration by using a hyaluronic acid bone-filling complex containing a hyaluronic acid hydrogel in which a decomposing rate is adjusted in accordance with an in-vivo bone regeneration period.
PCT/KR2009/001862 2008-04-25 2009-04-10 Hyaluronic acid bone-filling complex and fabrication method thereof WO2009131323A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0038777 2008-04-25
KR20080038777A KR101000491B1 (en) 2008-04-25 2008-04-25 Hyaluronic acid based artificial bone substitute and method for fabricating the same

Publications (2)

Publication Number Publication Date
WO2009131323A2 WO2009131323A2 (en) 2009-10-29
WO2009131323A3 true WO2009131323A3 (en) 2009-12-23

Family

ID=41217234

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/001862 WO2009131323A2 (en) 2008-04-25 2009-04-10 Hyaluronic acid bone-filling complex and fabrication method thereof

Country Status (2)

Country Link
KR (1) KR101000491B1 (en)
WO (1) WO2009131323A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101879331B (en) * 2010-06-26 2013-03-20 上海交通大学 Preparation method of amino-terminated hyperbranched polybenzimidazole composite film
KR101306748B1 (en) * 2012-03-29 2013-09-10 주식회사 바이오알파 Tunable hyaluronic acid-calcium phosphate complexes with delivery rate of growth factors and preparation method thereof
KR101443814B1 (en) * 2013-03-28 2014-09-30 주식회사 바이오알파 An injectable composition for bone defects and a preparation method therof
KR101650414B1 (en) 2014-09-30 2016-08-30 (주)아크로스 Manufacturing method of dental-bone filler including crosslinked hyaluronic acid
CN109628794B (en) * 2019-01-16 2020-10-13 太原理工大学 Low-temperature synthesis of Mg3-xZnxSb2(x is more than or equal to 0 and less than or equal to 0.3) material preparation method
DE202021004032U1 (en) 2020-08-29 2022-10-10 BioScientific Designs d.o.o A sterile medical device for bone replacement, preparation and use

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874417A (en) * 1993-11-30 1999-02-23 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
US6037519A (en) * 1997-10-20 2000-03-14 Sdgi Holdings, Inc. Ceramic fusion implants and compositions
US20030072805A1 (en) * 2000-01-11 2003-04-17 Kazuyuki Miyazawa Microgel and external compositions containing the same
KR20080020223A (en) * 2006-08-31 2008-03-05 포항공과대학교 산학협력단 Bone filling complex and method for fabricating the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874417A (en) * 1993-11-30 1999-02-23 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
US6037519A (en) * 1997-10-20 2000-03-14 Sdgi Holdings, Inc. Ceramic fusion implants and compositions
US20030072805A1 (en) * 2000-01-11 2003-04-17 Kazuyuki Miyazawa Microgel and external compositions containing the same
KR20080020223A (en) * 2006-08-31 2008-03-05 포항공과대학교 산학협력단 Bone filling complex and method for fabricating the same

Also Published As

Publication number Publication date
KR101000491B1 (en) 2010-12-14
KR20090112967A (en) 2009-10-29
WO2009131323A2 (en) 2009-10-29

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