WO2007070093A3 - Flexible apparatus and method for monitoring and delivery - Google Patents

Flexible apparatus and method for monitoring and delivery Download PDF

Info

Publication number
WO2007070093A3
WO2007070093A3 PCT/US2006/023194 US2006023194W WO2007070093A3 WO 2007070093 A3 WO2007070093 A3 WO 2007070093A3 US 2006023194 W US2006023194 W US 2006023194W WO 2007070093 A3 WO2007070093 A3 WO 2007070093A3
Authority
WO
WIPO (PCT)
Prior art keywords
sampling
sample
analysis
biological
delivery
Prior art date
Application number
PCT/US2006/023194
Other languages
French (fr)
Other versions
WO2007070093A2 (en
Inventor
John Frederick Currie
Makarand Paranjape
Original Assignee
Flexible Medical Systems Llc
John Frederick Currie
Makarand Paranjape
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2005/044287 external-priority patent/WO2006063063A2/en
Application filed by Flexible Medical Systems Llc, John Frederick Currie, Makarand Paranjape filed Critical Flexible Medical Systems Llc
Priority to CA002633827A priority Critical patent/CA2633827A1/en
Priority to JP2008544316A priority patent/JP2009518113A/en
Priority to US12/096,769 priority patent/US8333874B2/en
Priority to EP06773168A priority patent/EP1956977A4/en
Publication of WO2007070093A2 publication Critical patent/WO2007070093A2/en
Publication of WO2007070093A3 publication Critical patent/WO2007070093A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0537—Measuring body composition by impedance, e.g. tissue hydration or fat content
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6832—Means for maintaining contact with the body using adhesives
    • A61B5/6833—Adhesive patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
    • A61B2562/0215—Silver or silver chloride containing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
    • A61B2562/0217—Electrolyte containing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04—Arrangements of multiple sensors of the same type
    • A61B2562/043—Arrangements of multiple sensors of the same type in a linear array
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4519—Muscles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/45—For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4538—Evaluating a particular part of the muscoloskeletal system or a particular medical condition
    • A61B5/4542—Evaluating the mouth, e.g. the jaw
    • A61B5/4547—Evaluating teeth

Abstract

The present invention generally relates to a system and method that co-locates in a small flexible, configurable system and multi-level substrate sampling, rapid analysis, bio-sample storage and delivery functions to be performed on living tissues or matter obtained from living organisms. The types of the sampling may include chemical, biochemical, biological, thermal, mechanical, electrical, magnetic and optical sampling. In general, the analysis performed at the point of sampling measures the sample taken and records its value. The bio-sample storage function encapsulates a small sample of analyte and preserves it for subsequent examination or analysis, either on the organism by the system or at a remote location by an independent analysis system. Once stored, the sample can provide a record of a biological state at the precise time of sampling. The delivery at the point of sampling can include chemical, biochemical, biological, thermal, mechanical, electrical, magnetic and optical stimuli.
PCT/US2006/023194 2004-12-09 2006-06-14 Flexible apparatus and method for monitoring and delivery WO2007070093A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002633827A CA2633827A1 (en) 2004-12-09 2006-06-14 Flexible apparatus and method for monitoring and delivery
JP2008544316A JP2009518113A (en) 2005-12-09 2006-06-14 Flexible device and method for monitoring and delivery
US12/096,769 US8333874B2 (en) 2005-12-09 2006-06-14 Flexible apparatus and method for monitoring and delivery
EP06773168A EP1956977A4 (en) 2004-12-09 2006-06-14 Flexible apparatus and method for monitoring and delivery

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US2005/044287 WO2006063063A2 (en) 2004-12-09 2005-12-09 Apparatus and method for continuous real-time trace biomolecular sampling, analysis and delivery
USPCT/US2005/044287 2005-12-09

Publications (2)

Publication Number Publication Date
WO2007070093A2 WO2007070093A2 (en) 2007-06-21
WO2007070093A3 true WO2007070093A3 (en) 2007-08-09

Family

ID=38163369

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/023194 WO2007070093A2 (en) 2004-12-09 2006-06-14 Flexible apparatus and method for monitoring and delivery

Country Status (2)

Country Link
JP (1) JP2009518113A (en)
WO (1) WO2007070093A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9008761B2 (en) 2010-02-01 2015-04-14 Proteus Digital Health, Inc. Two-wrist data gathering system
US9014779B2 (en) 2010-02-01 2015-04-21 Proteus Digital Health, Inc. Data gathering system
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008008281A2 (en) 2006-07-07 2008-01-17 Proteus Biomedical, Inc. Smart parenteral administration system
JP5004169B2 (en) 2007-05-30 2012-08-22 ローム株式会社 Microchip manufacturing method
US8818477B2 (en) 2007-07-13 2014-08-26 University Of Massachusetts Physical performance monitoring and monitors
CN101755043B (en) * 2007-07-23 2013-06-19 埃葛梅崔克斯股份有限公司 Electrochemical test strip
JP5088148B2 (en) * 2008-01-16 2012-12-05 Ｔｄｋ株式会社 Method for measuring metabolite concentration and electrochemical sensor used therefor
JP4582224B2 (en) * 2008-05-02 2010-11-17 ソニー株式会社 Microbead manufacturing method and microbead
JP2010128365A (en) 2008-11-28 2010-06-10 Fujitsu Ltd Display device
JP5499342B2 (en) * 2008-11-28 2014-05-21 株式会社日立製作所 Sensor node, sensor network system, and data collection method
US8696917B2 (en) 2009-02-09 2014-04-15 Edwards Lifesciences Corporation Analyte sensor and fabrication methods
US20100219085A1 (en) * 2009-02-27 2010-09-02 Edwards Lifesciences Corporation Analyte Sensor Offset Normalization
IN2012DN00937A (en) * 2009-08-03 2015-04-03 Dune Medical Devices Ltd
IN2012DN00936A (en) 2009-08-03 2015-04-03 Dune Medical Devices Ltd
US20110046466A1 (en) * 2009-08-19 2011-02-24 Feldman Benjamin J Analyte Sensors Including Nanomaterials and Methods of Using Same
JP5735773B2 (en) * 2010-03-29 2015-06-17 シスメックス株式会社 Biological component analysis method and biological component analyzer
RU2013156970A (en) * 2011-06-23 2015-07-27 Университи Оф Вирджиния Патент Фоундэйшион UNIFIED PLATFORM FOR MONITORING AND MONITORING GLUCOSE LEVELS IN BLOOD IN PATIENTS WITH DIABETES MELLITUS
CA2794231C (en) * 2012-10-31 2018-08-14 Ioannidis Nektarios Periodontal probe with touch sensing
KR101386385B1 (en) 2013-01-25 2014-04-17 경북대학교 산학협력단 Antigen sensitivity improvers for surface plasmon resonance sensor
US9458488B2 (en) 2013-03-15 2016-10-04 Nanomix, Inc. Point of care sensor systems
ES2805474T3 (en) * 2014-01-21 2021-02-12 Univ California Salivary biosensors and biofuel cells
KR20170041291A (en) * 2014-08-11 2017-04-14 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 Devices and related methods for epidermal characterization of biofluids
CN109414227A (en) * 2016-04-26 2019-03-01 巴斯大学 Multiplexing for non-invasive monitoring substance is percutaneously extracted and detection device and its application method
WO2018080923A1 (en) * 2016-10-28 2018-05-03 Georgetown University Non-invasive passive interstitial fluid collector
EP3822628A4 (en) * 2018-07-09 2022-04-06 National Institute for Materials Science Diagnosing device, analysis method, and program
US11506673B2 (en) * 2018-11-18 2022-11-22 Hamed Golmohammadi Ghane Measurement of bilirubin concentration in blood samples
US11633129B2 (en) 2019-04-05 2023-04-25 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating redox cofactors
US11375931B2 (en) 2019-08-08 2022-07-05 Cambridge Medical Technologies LLC Non-invasive transdermal sampling and analysis device incorporating an electrochemical bioassay
US20210267501A1 (en) * 2020-02-27 2021-09-02 Cambridge Medical Technologies LLC Non-Invasive Transdermal Sampling and Analysis Device for Detection of Multiple Analytes

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5149629A (en) * 1987-04-07 1992-09-22 Ramot University Authority For Applied Research And Industrial Development Ltd. Coulometric assay system
US5711861A (en) * 1995-11-22 1998-01-27 Ward; W. Kenneth Device for monitoring changes in analyte concentration
US6342037B1 (en) * 1998-06-29 2002-01-29 The Procter & Gamble Company Device having fecal component sensor
US6572542B1 (en) * 2000-03-03 2003-06-03 Medtronic, Inc. System and method for monitoring and controlling the glycemic state of a patient
US20030130616A1 (en) * 1999-06-03 2003-07-10 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5149629A (en) * 1987-04-07 1992-09-22 Ramot University Authority For Applied Research And Industrial Development Ltd. Coulometric assay system
US5711861A (en) * 1995-11-22 1998-01-27 Ward; W. Kenneth Device for monitoring changes in analyte concentration
US6342037B1 (en) * 1998-06-29 2002-01-29 The Procter & Gamble Company Device having fecal component sensor
US20030130616A1 (en) * 1999-06-03 2003-07-10 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US6572542B1 (en) * 2000-03-03 2003-06-03 Medtronic, Inc. System and method for monitoring and controlling the glycemic state of a patient

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
US9008761B2 (en) 2010-02-01 2015-04-14 Proteus Digital Health, Inc. Two-wrist data gathering system
US9014779B2 (en) 2010-02-01 2015-04-21 Proteus Digital Health, Inc. Data gathering system

Also Published As

Publication number Publication date
WO2007070093A2 (en) 2007-06-21
JP2009518113A (en) 2009-05-07

Similar Documents

Publication Publication Date Title
WO2007070093A3 (en) Flexible apparatus and method for monitoring and delivery
WO2008039946A3 (en) Integrated meter for analyzing biological samples
CN101213447B (en) Blo drive apparatus, and assay method using the same
WO2007010087A3 (en) Health monitoring device, device modules and method
EP1686380A3 (en) Robotic apparatus for picking of cells and other applications with integrated spectroscopic capability
WO2007062225A3 (en) Test substrate handling apparatus
EP2491860A3 (en) Analyte monitoring
ATE481032T1 (en) DEVICE, SYSTEM AND METHOD FOR IN VIVO SAMPLING
CN105190310A (en) A biosensor device to target analytes in situ, in vivo, and/or in real time, and methods of making and using the same
WO2006063042A3 (en) Selecting patients for therapy with a her inhibitor
WO2007003344A3 (en) Device for quantitative analysis of a metabolite profile
AU2003296946A1 (en) A biological sample storage device and method for biological sample contamination testing
EP1890142A3 (en) Blood coagulation analyzer and blood coagulation analyzing method
EP1966731A4 (en) Method for ascertaining interferants in small liquid samples in an automated clinical analyzer
ATE347307T1 (en) STRIP FOR PACKAGING A MULTIPLE OF FLUID SAMPLING AND TESTING DEVICES AND METHOD FOR PRODUCING AND USING THE STRIP
WO2008064067A3 (en) Method for the sequential analysis of different components in a single biological sample and reagents therefor
WO2010135603A3 (en) Method for cancer detection, diagnosis and prognosis
WO2008014132A3 (en) Combination analyte measurement device and method of use
WO2010104345A3 (en) Apparatus for integrated real-time nucleic acid analysis, and method for detecting a target nucleic acid using same
WO2002057753A3 (en) Rapid test for biological substances using ftir
EP1898215A4 (en) Method of assaying endocrine substance in specimen
EP2335568A3 (en) Portable analytical device, in particular blood glucose measuring device
CN103675031B (en) A kind of high-flux cell detection method of toxicity
EP2662453A3 (en) Detection and treatment of schizophrenia
EP1517140A3 (en) Method and device for diagnostic investigation of biological samples

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2008544316

Country of ref document: JP

Ref document number: 2633827

Country of ref document: CA

Ref document number: 4952/DELNP/2008

Country of ref document: IN

Ref document number: 2006773168

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 200680052540.8

Country of ref document: CN

WWE Wipo information: entry into national phase

Ref document number: 12096769

Country of ref document: US