WO2007056247A3 - Delivery of agents such as cells to tissue - Google Patents

Delivery of agents such as cells to tissue Download PDF

Info

Publication number
WO2007056247A3
WO2007056247A3 PCT/US2006/043133 US2006043133W WO2007056247A3 WO 2007056247 A3 WO2007056247 A3 WO 2007056247A3 US 2006043133 W US2006043133 W US 2006043133W WO 2007056247 A3 WO2007056247 A3 WO 2007056247A3
Authority
WO
WIPO (PCT)
Prior art keywords
cells
powered drive
container
control system
tissue
Prior art date
Application number
PCT/US2006/043133
Other languages
French (fr)
Other versions
WO2007056247A2 (en
Inventor
Arthur E Uber Iii
Alan D Hirschman
Evan Facher
Eugene A Gelblum
David M Griffiths
Edward J Rhinehart
David M Reilly
Kevin P Cowan
Page Cedarholm
Barry L Tucker
Mark Trocki
David Mishler
Henry E Bartony Jr
Robert Parks
Original Assignee
Medrad Inc
Arthur E Uber Iii
Alan D Hirschman
Evan Facher
Eugene A Gelblum
David M Griffiths
Edward J Rhinehart
David M Reilly
Kevin P Cowan
Page Cedarholm
Barry L Tucker
Mark Trocki
David Mishler
Henry E Bartony Jr
Robert Parks
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medrad Inc, Arthur E Uber Iii, Alan D Hirschman, Evan Facher, Eugene A Gelblum, David M Griffiths, Edward J Rhinehart, David M Reilly, Kevin P Cowan, Page Cedarholm, Barry L Tucker, Mark Trocki, David Mishler, Henry E Bartony Jr, Robert Parks filed Critical Medrad Inc
Priority to US12/092,448 priority Critical patent/US8182444B2/en
Publication of WO2007056247A2 publication Critical patent/WO2007056247A2/en
Publication of WO2007056247A3 publication Critical patent/WO2007056247A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1443—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
    • A61J1/1456—Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters using liquid filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1475—Inlet or outlet ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/005—Devices for introducing or retaining media, e.g. remedies, in cavities of the body for contrast media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3145—Filters incorporated in syringes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection

Abstract

A system for delivering a fluid comprising cells to tissue of a patient, includes: a least a first container for holding an injection fluid in which the agent is carried; a first powered drive in operative connection with the container, the first powered drive being operable to pressurize contents of the container; a control system in operative connection with the first powered drive and operative to control the first powered drive; a fluid path in fluid connection with the container, the fluid path including a patient interface adapted to deposit the cells within tissue of the patient; a sensor system; and a communication system in connection with at least the control system and the sensor system. The communication system is adapted to provide information to the control system. The control system in adapted to transmit a control signal to at least the first powered drive based at least in part on information provided to the control system. The cells can for example be pregenitor cells or stem cells.
PCT/US2006/043133 2005-11-04 2006-11-06 Delivery of agents such as cells to tissue WO2007056247A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/092,448 US8182444B2 (en) 2005-11-04 2006-11-06 Delivery of agents such as cells to tissue

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US73403505P 2005-11-04 2005-11-04
US60/734,035 2005-11-04
US74222405P 2005-12-05 2005-12-05
US60/742,224 2005-12-05
US77120606P 2006-02-07 2006-02-07
US60/771,206 2006-02-07
US11/460,635 2006-07-28
US11/460,635 US7713232B2 (en) 2005-11-04 2006-07-28 System for washing and processing of cells for delivery thereof to tissue

Publications (2)

Publication Number Publication Date
WO2007056247A2 WO2007056247A2 (en) 2007-05-18
WO2007056247A3 true WO2007056247A3 (en) 2009-05-07

Family

ID=38004763

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2006/043133 WO2007056247A2 (en) 2005-11-04 2006-11-06 Delivery of agents such as cells to tissue
PCT/US2006/043134 WO2007053779A2 (en) 2005-11-04 2006-11-06 Delivery of agents to tissue

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2006/043134 WO2007053779A2 (en) 2005-11-04 2006-11-06 Delivery of agents to tissue

Country Status (5)

Country Link
US (3) US7713232B2 (en)
EP (1) EP1942981A4 (en)
JP (1) JP2009524442A (en)
CA (1) CA2630686A1 (en)
WO (2) WO2007056247A2 (en)

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CA2630686A1 (en) 2007-05-10
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US20140163475A1 (en) 2014-06-12
WO2007053779A3 (en) 2007-11-08
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US9629780B2 (en) 2017-04-25
US20110028908A1 (en) 2011-02-03
US20070106208A1 (en) 2007-05-10
US7713232B2 (en) 2010-05-11
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US8414765B2 (en) 2013-04-09
WO2007053779A2 (en) 2007-05-10

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