WO2007047420A8 - Drug-impregnated encasement - Google Patents

Drug-impregnated encasement

Info

Publication number
WO2007047420A8
WO2007047420A8 PCT/US2006/040038 US2006040038W WO2007047420A8 WO 2007047420 A8 WO2007047420 A8 WO 2007047420A8 US 2006040038 W US2006040038 W US 2006040038W WO 2007047420 A8 WO2007047420 A8 WO 2007047420A8
Authority
WO
WIPO (PCT)
Prior art keywords
sleeve
drug
biologically
impregnated
compatible material
Prior art date
Application number
PCT/US2006/040038
Other languages
French (fr)
Other versions
WO2007047420A2 (en
WO2007047420A3 (en
Inventor
Mark Thomas Fulmer
David A Armbruster
Robert Frigg
Elliot A Gruskin
Sean Hamilton Kerr
Original Assignee
Synthes Usa
Synthes Gmbh
Mark Thomas Fulmer
David A Armbruster
Robert Frigg
Elliot A Gruskin
Sean Hamilton Kerr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2008535700A priority Critical patent/JP5137841B2/en
Application filed by Synthes Usa, Synthes Gmbh, Mark Thomas Fulmer, David A Armbruster, Robert Frigg, Elliot A Gruskin, Sean Hamilton Kerr filed Critical Synthes Usa
Priority to CN2006800378818A priority patent/CN101437571B/en
Priority to KR1020137008793A priority patent/KR101420988B1/en
Priority to EP06816850.9A priority patent/EP1933936B1/en
Priority to AU2006304229A priority patent/AU2006304229A1/en
Priority to US12/089,574 priority patent/US8900620B2/en
Priority to EP19163491.4A priority patent/EP3566742A1/en
Priority to BRPI0617325A priority patent/BRPI0617325B8/en
Priority to CA2625264A priority patent/CA2625264C/en
Priority to KR1020087011335A priority patent/KR101377900B1/en
Publication of WO2007047420A2 publication Critical patent/WO2007047420A2/en
Publication of WO2007047420A3 publication Critical patent/WO2007047420A3/en
Publication of WO2007047420A8 publication Critical patent/WO2007047420A8/en
Priority to US13/835,609 priority patent/US20130289621A1/en
Priority to US14/503,594 priority patent/US9579260B2/en
Priority to US15/417,409 priority patent/US20170136223A1/en
Priority to US15/726,634 priority patent/US10814112B2/en
Priority to US17/065,727 priority patent/US20210031013A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary pins, nails or other devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8028—Cushions, i.e. elements forming interface between bone plate and bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831—Material properties
    • A61B2017/00893—Material properties pharmaceutically effective
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30907—Nets or sleeves applied to surface of prostheses or in cement
    • A61F2002/30919—Sleeves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00—General characteristics or adaptations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/04—General characteristics of the apparatus implanted
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1002—Methods of surface bonding and/or assembly therefor with permanent bending or reshaping or surface deformation of self sustaining lamina
    • Y10T156/1051—Methods of surface bonding and/or assembly therefor with permanent bending or reshaping or surface deformation of self sustaining lamina by folding

Abstract

A drug-impregnated sleeve for encasing a medical implant is provided. In one embodiment, the sleeve may include a body made of a biologically-compatible material that defines an internal cavity configured to receive the medical implant. In one embodiment, the biologically-compatible material is bioresorbable. The body may include a plurality of apertures, such as perforations or holes, extending from the cavity through the body. The sleeve may further include a first end, a second end, and a drug impregnated into the resorbable sheet. In one possible embodiment, the first end of the sleeve may be open for receiving the medical implant therethrough and the second end may be closed. The implant may be encased in the sleeve and implanted into a patient from which the drug is dispensed in vivo over time to tissue surrounding the implantation site. In one embodiment, the body is made from at least one sheet of a biologically-compatible material, hi one embodiment, the sleeve may be made in least in part from caprolactone to add stretchability to the sleeve.
PCT/US2006/040038 2005-10-13 2006-10-12 Drug-impregnated encasement WO2007047420A2 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
BRPI0617325A BRPI0617325B8 (en) 2005-10-13 2006-10-12 biologically compatible glove
EP19163491.4A EP3566742A1 (en) 2005-10-13 2006-10-12 Drug-impregnated encasement
CN2006800378818A CN101437571B (en) 2005-10-13 2006-10-12 Drug-impregnated encasement
KR1020137008793A KR101420988B1 (en) 2005-10-13 2006-10-12 Drug-impregnated encasement
EP06816850.9A EP1933936B1 (en) 2005-10-13 2006-10-12 Drug-impregnated encasement
AU2006304229A AU2006304229A1 (en) 2005-10-13 2006-10-12 Drug-impregnated encasement
US12/089,574 US8900620B2 (en) 2005-10-13 2006-10-12 Drug-impregnated encasement
JP2008535700A JP5137841B2 (en) 2005-10-13 2006-10-12 Drug impregnation container
CA2625264A CA2625264C (en) 2005-10-13 2006-10-12 Drug-impregnated sleeve for a medical implant
KR1020087011335A KR101377900B1 (en) 2005-10-13 2006-10-12 Drug-impregnated encasement
US13/835,609 US20130289621A1 (en) 2005-10-13 2013-03-15 Drug-Impregnated Encasement
US14/503,594 US9579260B2 (en) 2005-10-13 2014-10-01 Drug-impregnated encasement
US15/417,409 US20170136223A1 (en) 2005-10-13 2017-01-27 Drug-impregnated encasement
US15/726,634 US10814112B2 (en) 2005-10-13 2017-10-06 Drug-impregnated encasement
US17/065,727 US20210031013A1 (en) 2005-10-13 2020-10-08 Drug-impregnated encasement

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72680805P 2005-10-13 2005-10-13
US60/726,808 2005-10-13

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US12/089,574 A-371-Of-International US8900620B2 (en) 2005-10-13 2006-10-12 Drug-impregnated encasement
US13/835,609 Continuation US20130289621A1 (en) 2005-10-13 2013-03-15 Drug-Impregnated Encasement
US14/503,594 Continuation US9579260B2 (en) 2005-10-13 2014-10-01 Drug-impregnated encasement

Publications (3)

Publication Number Publication Date
WO2007047420A2 WO2007047420A2 (en) 2007-04-26
WO2007047420A3 WO2007047420A3 (en) 2007-12-06
WO2007047420A8 true WO2007047420A8 (en) 2008-03-13

Family

ID=37963108

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/040038 WO2007047420A2 (en) 2005-10-13 2006-10-12 Drug-impregnated encasement

Country Status (10)

Country Link
US (6) US8900620B2 (en)
EP (2) EP1933936B1 (en)
JP (3) JP5137841B2 (en)
KR (2) KR101420988B1 (en)
CN (2) CN101437571B (en)
AU (1) AU2006304229A1 (en)
BR (1) BRPI0617325B8 (en)
CA (1) CA2625264C (en)
WO (1) WO2007047420A2 (en)
ZA (1) ZA200803822B (en)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000015273A1 (en) 1998-09-11 2000-03-23 Gerhard Schmidmaier Biologically active implants
CN101437571B (en) 2005-10-13 2013-01-02 斯恩蒂斯有限公司 Drug-impregnated encasement
DE102007032156A1 (en) * 2007-07-03 2008-10-23 Aesculap Ag Textile vascular prosthesis
US20090024147A1 (en) * 2007-07-18 2009-01-22 Ralph James D Implantable mesh for musculoskeletal trauma, orthopedic reconstruction and soft tissue repair
AU2008349523B2 (en) * 2008-01-29 2013-10-24 Zimmer, Inc. Implant device for use in an implant system
EP2346421A1 (en) * 2008-10-15 2011-07-27 Bioshape Solutions Inc. Device and method for delivery of therapeutic agents via internal implants
BRPI1008524A2 (en) 2009-02-06 2015-08-25 David Cheung "biocompatible resorbable biphasic collagen membrane and its production method"
US8454706B2 (en) 2009-02-25 2013-06-04 Brian C. de Beaubien Antibiotic delivery system and method for treating an infected synovial joint during re-implantation of an orthopedic prosthesis
US9439685B2 (en) * 2009-05-12 2016-09-13 Bullard Spine, Llc Multi-layer osteoinductive, osteogenic, and osteoconductive carrier
DK2453939T3 (en) 2009-07-16 2014-02-03 Anatoli D Dosta bone implants
US8652505B2 (en) * 2010-03-04 2014-02-18 Southwest Research Institute Coating for medical implants
US8617097B2 (en) 2010-05-24 2013-12-31 Cochlear Limited Drug-delivery accessory for an implantable medical device
SE535125C2 (en) * 2010-06-03 2012-04-24 Tigran Technologies Ab Publ 3D moldable and perforated retention sheet
WO2013028951A1 (en) 2011-08-25 2013-02-28 Synthes Usa, Llc Peek or pmma transparent implant comprising an adhesive layer of an uncured polymer.
AR084499A1 (en) 2011-11-16 2013-05-22 S L S A Lab A DISPOSABLE INTRAMEDULAR DEVICE FOR TRANSITORY USE FOR THE TREATMENT OF INFECTIONS IN EXTREMITIES
TWI590843B (en) * 2011-12-28 2017-07-11 信迪思有限公司 Films and methods of manufacture
DE102012006454A1 (en) * 2012-03-30 2013-10-02 Heraeus Medical Gmbh Anti-infective spacer for osteosynthesis plates
US9017055B2 (en) 2012-07-12 2015-04-28 Biomet Manufacturing, Llc Device for coating intramedullary rods with cement
US9034052B2 (en) * 2013-01-14 2015-05-19 Warsaw Orthopedic, Inc. Delivery systems containing bioactive materials
US9579133B2 (en) * 2013-02-01 2017-02-28 James Guthlein Internal fixation device
US9585695B2 (en) 2013-03-15 2017-03-07 Woven Orthopedic Technologies, Llc Surgical screw hole liner devices and related methods
EP3323364A1 (en) * 2013-04-12 2018-05-23 Zimmer GmbH Orthopedic plate
AU2014281010B2 (en) * 2013-06-21 2018-05-10 DePuy Synthes Products, Inc. Films and methods of manufacture
US10232090B2 (en) 2013-08-23 2019-03-19 Southwest Research Institute Electrophoretically deposited strontium fluoride nanoparticle/polymer coatings for medical implants
US8956394B1 (en) 2014-08-05 2015-02-17 Woven Orthopedic Technologies, Llc Woven retention devices, systems and methods
US9907593B2 (en) 2014-08-05 2018-03-06 Woven Orthopedic Technologies, Llc Woven retention devices, systems and methods
US9943351B2 (en) 2014-09-16 2018-04-17 Woven Orthopedic Technologies, Llc Woven retention devices, systems, packaging, and related methods
USD740427S1 (en) 2014-10-17 2015-10-06 Woven Orthopedic Technologies, Llc Orthopedic woven retention device
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
US10433965B2 (en) * 2015-06-17 2019-10-08 Joint Purification Systems Llc Total joint replacement infection control devices and methods
US10555758B2 (en) 2015-08-05 2020-02-11 Woven Orthopedic Technologies, Llc Tapping devices, systems and methods for use in bone tissue
TWI706898B (en) * 2015-12-09 2020-10-11 美商脫其泰有限責任公司 Method of packaging a multi-monodose container
US10596660B2 (en) 2015-12-15 2020-03-24 Howmedica Osteonics Corp. Porous structures produced by additive layer manufacturing
US10383731B2 (en) 2016-02-24 2019-08-20 Warsaw Orthopedic, Inc. Spinal implant system and method
JP2019536503A (en) * 2016-09-28 2019-12-19 オーキッド・メディカル・プライベイト・リミテッドＯｒｃｈｉｄ Ｍｅｄｉｃａｌ Ｐｔｅ Ｌｔｄ Elastic bioabsorbable encasement for implants
US11707611B2 (en) 2016-11-08 2023-07-25 W. L. Gore & Associates, Inc. Implantable apparatus for retention of biological moieties
EP3551105A4 (en) 2016-12-09 2020-07-29 Woven Orthopedic Technologies, LLC Retention devices, lattices and related systems and methods
US10709576B2 (en) 2017-04-28 2020-07-14 Warsaw Orthopedic, Inc. Bone material dispensing apparatus and methods
US11628517B2 (en) 2017-06-15 2023-04-18 Howmedica Osteonics Corp. Porous structures produced by additive layer manufacturing
CA3065336A1 (en) 2017-06-26 2019-01-03 Dignity Health Systems and methods for a spinal shield for protecting the spinal cord and dura during surgical procedures
CN107456665B (en) * 2017-09-13 2018-06-29 成都迪康中科生物医学材料有限公司 A kind of degradable conduit for loading drug particle
WO2019071243A1 (en) 2017-10-06 2019-04-11 Foundry Therapeutics, Inc. Implantable depots for controlled release of therapeutic agents
EP3479798B1 (en) 2017-11-03 2023-06-21 Howmedica Osteonics Corp. Flexible construct for femoral reconstruction
US10881762B2 (en) * 2017-11-15 2021-01-05 De Novo Orthopedics Inc. Method for manufacturing bioinductive patch
NL2020071B1 (en) 2017-12-12 2019-06-21 Umc Utrecht Holding Bv Deformable body and combination of such deformable body and a surgical screw element.
US10646252B2 (en) * 2018-03-08 2020-05-12 Modern Surgical Solutions, Llc Medication sleeve for a trocar assembly
CN110141760B (en) * 2019-06-05 2021-10-08 山东百多安医疗器械股份有限公司 Centrum forming expansion balloon with drug loaded on surface and preparation method thereof
US11583403B2 (en) 2019-11-15 2023-02-21 Warsaw Orthopedic, Inc. Bone implant holding and shaping tray
US20230414366A1 (en) * 2022-06-24 2023-12-28 SECADA MEDICAL LLC dba VENTRIS MEDICAL, LLC Bone graft system

Family Cites Families (319)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1181333A (en) 1957-08-20 1959-06-15 Comp Generale Electricite Device allowing to detect if a point of an electrical installation is under tension, and to check the phase concordance between the voltages at two points of the said installation
FR1183333A (en) 1957-09-25 1959-07-06 Omniplast Process for the production, by casting, of plastic film articles and, in particular, of perforated film articles
US3155095A (en) 1961-02-07 1964-11-03 Adolph M Brown Anastomosis method and means
US3719736A (en) 1970-10-08 1973-03-06 Gen Foods Corp Method of producing perforated plastic film
US3949037A (en) 1972-09-14 1976-04-06 Dacor, Incorporated Method of making a simulated brick having a configured undercut face and a reverse surface having a sharp upstanding peripheral edge
US4148871A (en) 1977-10-11 1979-04-10 Pitt Colin G Sustained subdermal delivery ofdrugs using poly(ε-caprolactone) and its copolymers
SU683207A1 (en) 1977-12-27 1985-03-07 Предприятие П/Я А-7924 Method of obtaining built-up polymethylacrylate
DE2806609C2 (en) 1978-02-16 1980-03-13 Anton Dr. 4400 Muenster Haerle Osteosynthesis aids
FR2445763A1 (en) 1979-01-03 1980-08-01 Hureau Jean Claude PROCESS FOR THE EXTRUSION OF A THERMOPLASTIC SHEATH IN THE FORM OF A TUBULAR FILM PROVIDED WITH PERFORATIONS AND DEVICE FOR CARRYING OUT THE METHOD
CA1190855A (en) 1980-09-03 1985-07-23 Rolf W. Pfirrmann Treatment of osteitis
US4605730A (en) 1982-10-01 1986-08-12 Ethicon, Inc. Surgical articles of copolymers of glycolide and ε-caprolactone and methods of producing the same
US4774091A (en) 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
US4659700A (en) 1984-03-02 1987-04-21 Johnson & Johnson Products, Inc. Chitosan-glycerol-water gel
US4605414A (en) 1984-06-06 1986-08-12 John Czajka Reconstruction of a cruciate ligament
IT1186142B (en) * 1984-12-05 1987-11-18 Medinvent Sa TRANSLUMINAL IMPLANTATION DEVICE
DE3445738A1 (en) 1984-12-14 1986-06-19 Draenert Klaus IMPLANT FOR BONE REINFORCEMENT AND ANCHORING OF BONE SCREWS, IMPLANTS OR IMPLANT PARTS
DE3533369A1 (en) 1985-09-19 1987-03-19 Alois Prof Dr Med Bloemer ANTIBIOTIC CONTAINER AND ITS USE AS SURGICAL PLASTIC MATERIAL
JPH0824347B2 (en) 1986-05-12 1996-03-06 松下電器産業株式会社 Contour corrector for color television camera
US4730726A (en) 1987-04-21 1988-03-15 United States Surgical Corporation Sealed sterile package
DE3800259A1 (en) 1988-01-05 1989-07-13 Mecron Med Prod Gmbh IMPLANTABLE PROSTHESIS
US4888023B1 (en) 1988-01-19 1996-01-23 Osteonics Corp Femoral prosthesis with uncoupled distal tip
US5100668A (en) 1988-06-14 1992-03-31 Massachusetts Institute Of Technology Controlled release systems containing heparin and growth factors
DE3831657A1 (en) 1988-09-17 1990-03-22 Boehringer Ingelheim Kg DEVICE FOR THE OSTEOSYNTHESIS AND METHOD FOR THE PRODUCTION THEREOF
ES2075063T3 (en) 1988-11-30 1995-10-01 Nihon Tokkyo Kanri Co Ltd SEPARABLE FILMS.
US5147400A (en) 1989-05-10 1992-09-15 United States Surgical Corporation Connective tissue prosthesis
US5324519A (en) 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
JPH0385179A (en) 1989-08-30 1991-04-10 Sumitomo Bakelite Co Ltd Medical balloon catheter
US5268178A (en) 1989-09-25 1993-12-07 The Board Of Regents, The University Of Texas System Biodegradable antibiotic implants and methods of their use in treating and preventing infections
US5093319A (en) 1989-10-31 1992-03-03 Pfizer Hospital Products Group, Inc. Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions
DE3939363A1 (en) 1989-11-29 1991-06-06 Aesculap Ag Resorbable plastic implants production - by extruding rectangular poly-L-lactide cross=section and stretching it within specific temp. range to acquire high mechanical strength
JPH0622553Y2 (en) 1989-12-19 1994-06-15 トヨタ自動車株式会社 Automatic welding equipment feeder
DE4010051C1 (en) 1990-03-29 1991-08-08 Upat Gmbh & Co, 7830 Emmendingen, De
IT1248934B (en) 1990-06-01 1995-02-11 Fidia Spa BIOCOMPATIBLE PERFORATED MEMBRANES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS A SUPPORT FOR THE IN VITRO GROWTH OF EPITHELIAL CELLS, ARTIFICIAL LEATHER THUS OBTAINED AND THEIR USE IN LEATHER TRANSPLANTS
US5281221A (en) 1990-12-05 1994-01-25 Tadych Kevin L Antimicrobial device for use in external fixators
JPH04221538A (en) 1990-12-21 1992-08-12 Olympus Optical Co Ltd Device for forming hole
GB2251795B (en) 1991-01-17 1995-02-08 Minnesota Mining & Mfg Orthopaedic implant
FR2673843B1 (en) 1991-03-14 1995-01-13 Centre Nat Rech Scient IMPLANTABLE, BIORESORBABLE PHARMACEUTICAL COMPOSITION BASED ON POLY (LACTIC ACID), INTENDED TO IMPLEMENT A LOCAL INTERNAL ANTIBOTHERAPY.
US5800829A (en) 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
ES2107537T3 (en) 1991-04-25 1997-12-01 Univ Brown Res Found IMMUNO INSULATED BIOCOMPATIBLE VEHICLE IMPLANTABLE TO SUPPLY SELECTED THERAPEUTIC PRODUCTS.
FR2678823B1 (en) 1991-07-11 1995-07-07 Legrand Jean Jacques DEVICE FOR REINFORCING A LIGAMENT DURING A LIGAMENT PLASTY.
EP0523926A3 (en) 1991-07-15 1993-12-01 Smith & Nephew Richards Inc Prosthetic implants with bioabsorbable coating
US5260066A (en) 1992-01-16 1993-11-09 Srchem Incorporated Cryogel bandage containing therapeutic agent
US5571193A (en) 1992-03-12 1996-11-05 Kampner; Stanley L. Implant with reinforced resorbable stem
US6071567A (en) 1992-03-25 2000-06-06 Reeves Brothers, Inc. Formation of compressible ply containing high melting point thermoplastic microspheres and printing blankets comprising same
EP0633798B1 (en) 1992-03-31 2003-05-07 Boston Scientific Corporation Vascular filter
US6497709B1 (en) 1992-03-31 2002-12-24 Boston Scientific Corporation Metal medical device
US7101392B2 (en) 1992-03-31 2006-09-05 Boston Scientific Corporation Tubular medical endoprostheses
US5955095A (en) 1992-04-22 1999-09-21 Brown University Research Foundation Microporous macrocapsules
US5383928A (en) 1992-06-10 1995-01-24 Emory University Stent sheath for local drug delivery
US5521193A (en) 1992-06-24 1996-05-28 G. D. Searle & Co. Benzimidazole compounds
JPH0744936Y2 (en) 1992-06-29 1995-10-11 サンデン株式会社 Showcase drainage structure
DE4222380A1 (en) * 1992-07-08 1994-01-13 Ernst Peter Prof Dr M Strecker Endoprosthesis implantable percutaneously in a patient's body
KR950703910A (en) 1992-11-16 1995-11-17 윌리암 엠.잭슨 Microporous Macrocapsules (MICROPOROUS MACROCAPSULES)
YU48736B (en) 1992-12-16 1999-09-27 Milorad prof. dr. Mitković Mechanical device for outside bone fixation
US5468253A (en) 1993-01-21 1995-11-21 Ethicon, Inc. Elastomeric medical device
CA2114290C (en) 1993-01-27 2006-01-10 Nagabushanam Totakura Post-surgical anti-adhesion device
US5716981A (en) 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use
DE69432734T2 (en) 1993-09-14 2004-04-29 Smith & Nephew, Inc., Memphis Biological tape replacement
US6248110B1 (en) 1994-01-26 2001-06-19 Kyphon, Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
US5656605A (en) 1994-01-26 1997-08-12 Institute Of Molecular Biology, Inc. Device to promote drug-induced nerve regeneration
US20030032963A1 (en) 2001-10-24 2003-02-13 Kyphon Inc. Devices and methods using an expandable body with internal restraint for compressing cancellous bone
US6241734B1 (en) 1998-08-14 2001-06-05 Kyphon, Inc. Systems and methods for placing materials into bone
WO2003059213A2 (en) 1994-01-26 2003-07-24 Kyphon Inc. Inflatable device for use in surgical protocol relating to fixation of bone
US6716216B1 (en) 1998-08-14 2004-04-06 Kyphon Inc. Systems and methods for treating vertebral bodies
US5507814A (en) 1994-03-30 1996-04-16 Northwestern University Orthopedic implant with self-reinforced mantle
US6165210A (en) 1994-04-01 2000-12-26 Gore Enterprise Holdings, Inc. Self-expandable helical intravascular stent and stent-graft
US6001123A (en) 1994-04-01 1999-12-14 Gore Enterprise Holdings Inc. Folding self-expandable intravascular stent-graft
DE4414675C1 (en) 1994-04-27 1995-09-28 Kirsch Axel Covering device for bone defects and method for their production
US5947893A (en) 1994-04-27 1999-09-07 Board Of Regents, The University Of Texas System Method of making a porous prothesis with biodegradable coatings
US5693085A (en) * 1994-04-29 1997-12-02 Scimed Life Systems, Inc. Stent with collagen
WO1995029646A1 (en) 1994-04-29 1995-11-09 Boston Scientific Corporation Medical prosthetic stent and method of manufacture
US20030086975A1 (en) 2001-11-08 2003-05-08 Timothy Ringeisen Method for making a porous Polymeric material
JP3125579B2 (en) 1994-05-24 2001-01-22 三菱マテリアル株式会社 Biological cement filling equipment
DE69512067T2 (en) 1994-06-30 2000-04-27 Procter & Gamble LIQUID-CONDUCTIVE FABRIC WITH SURFACE ENERGY RADIENTS
JP3250127B2 (en) 1994-07-14 2002-01-28 三菱マテリアル株式会社 Biological cement injection jig
DE4424883A1 (en) 1994-07-14 1996-01-18 Merck Patent Gmbh Femoral prosthesis
US6331188B1 (en) 1994-08-31 2001-12-18 Gore Enterprise Holdings, Inc. Exterior supported self-expanding stent-graft
US6015429A (en) 1994-09-08 2000-01-18 Gore Enterprise Holdings, Inc. Procedures for introducing stents and stent-grafts
US5489305A (en) 1994-10-03 1996-02-06 Timesh, Inc. Mandibular prostheses
ES2259179T3 (en) 1994-12-02 2006-09-16 Omeros Corporation REPAIR SYSTEM FOR TENDONS AND LIGAMENTS.
US5637113A (en) * 1994-12-13 1997-06-10 Advanced Cardiovascular Systems, Inc. Polymer film for wrapping a stent structure
IL116433A (en) 1994-12-19 2002-02-10 Galen Chemicals Ltd INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS
US5612052A (en) 1995-04-13 1997-03-18 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US6060640A (en) 1995-05-19 2000-05-09 Baxter International Inc. Multiple-layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
ES2278091T3 (en) 1995-11-08 2007-08-01 Zimmer Gmbh DEVICE FOR INTRODUCING AN IMPLANT, IN PARTICULAR AN INTERVERTEBRAL PROTESIS.
CN1206353A (en) * 1995-11-21 1999-01-27 E·N·勒纳 Device for enhanced delivery of biologically active substances and compounds in organism
JPH09201330A (en) 1996-01-25 1997-08-05 Nissho Corp Drainage tube assembly
FR2745710B1 (en) 1996-03-11 1998-05-29 Rippstein Pascal Francois TENDON PASSING DEVICE
DE19646212A1 (en) 1996-11-08 1998-05-14 Pelikan Scotland Ltd Multi-layer composite body
US5755720A (en) 1997-01-03 1998-05-26 Mikhail Michael W E Method and apparatus for performing hip prosthesis surgery
US5713904A (en) 1997-02-12 1998-02-03 Third Millennium Engineering, Llc Selectively expandable sacral fixation screw-sleeve device
AUPO530997A0 (en) * 1997-02-25 1997-03-20 Esnouf, Philip Stuart Surgical aid for connective tissue grafting and method for employing same
AU7295398A (en) 1997-05-15 1998-12-08 Hayes Medical, Inc. Temporary implantable prosthesis
US6306166B1 (en) 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
US6254627B1 (en) 1997-09-23 2001-07-03 Diseno Y Desarrollo Medico S.A. De C.V. Non-thrombogenic stent jacket
US6468300B1 (en) 1997-09-23 2002-10-22 Diseno Y Desarrollo Medico, S.A. De C.V. Stent covered heterologous tissue
GB2329840C (en) * 1997-10-03 2007-10-05 Johnson & Johnson Medical Biopolymer sponge tubes
US6986788B2 (en) 1998-01-30 2006-01-17 Synthes (U.S.A.) Intervertebral allograft spacer
US7087082B2 (en) 1998-08-03 2006-08-08 Synthes (Usa) Bone implants with central chambers
US6143033A (en) 1998-01-30 2000-11-07 Synthes (Usa) Allogenic intervertebral implant
USRE38614E1 (en) 1998-01-30 2004-10-05 Synthes (U.S.A.) Intervertebral allograft spacer
US5984926A (en) 1998-02-24 1999-11-16 Jones; A. Alexander M. Bone screw shimming and bone graft containment system and method
US6494898B1 (en) 1998-02-25 2002-12-17 United States Surgical Corporation Absorbable copolymers and surgical articles fabricated therefrom
US5984966A (en) * 1998-03-02 1999-11-16 Bionx Implants Oy Bioabsorbable bone block fixation implant
AU3203599A (en) 1998-04-01 1999-10-18 Parallax Medical, Inc. Pressure applicator for hard tissue implant placement
CA2327789C (en) 1998-04-07 2007-09-04 Macropore, Inc. Membrane with tissue-guiding surface corrugations
US6280411B1 (en) 1998-05-18 2001-08-28 Scimed Life Systems, Inc. Localized delivery of drug agents
US6719773B1 (en) 1998-06-01 2004-04-13 Kyphon Inc. Expandable structures for deployment in interior body regions
DE69942858D1 (en) 1998-06-01 2010-11-25 Kyphon S A R L DEFINABLE, PREFORMED STRUCTURES FOR ESTABLISHMENT IN REGIONS INSIDE THE BODY
US6165202A (en) 1998-07-06 2000-12-26 United States Surgical Corporation Absorbable polymers and surgical articles fabricated therefrom
WO2000007527A1 (en) 1998-08-03 2000-02-17 Synthes Ag Chur Intervertebral allograft spacer
CA2338788A1 (en) * 1998-09-02 2000-03-09 Scimed Life Systems, Inc. Drug delivery device for stent
US6350284B1 (en) 1998-09-14 2002-02-26 Bionx Implants, Oy Bioabsorbable, layered composite material for guided bone tissue regeneration
US6248112B1 (en) 1998-09-30 2001-06-19 C. R. Bard, Inc. Implant delivery system
US6235869B1 (en) 1998-10-20 2001-05-22 United States Surgical Corporation Absorbable polymers and surgical articles fabricated therefrom
US6063395A (en) 1998-11-12 2000-05-16 Leiras Oy Drug delivery device especially for the delivery of progestins and estrogens
US6117442A (en) 1998-11-12 2000-09-12 Leiras Oy Drug delivery device, especially for the delivery of androgens
US6884427B1 (en) * 1999-02-08 2005-04-26 Aderans Research Institute, Inc. Filamentary means for introducing agents into tissue of a living host
US6104276A (en) * 1999-03-22 2000-08-15 Samsung Electro-Mechanics Co., Ltd. FBT, its bleeder resistor, and device for coupling bleeder resistor
US6221097B1 (en) 1999-03-22 2001-04-24 Scimed Life System, Inc. Lubricated sleeve material for stent delivery
US6443980B1 (en) 1999-03-22 2002-09-03 Scimed Life Systems, Inc. End sleeve coating for stent delivery
US6331186B1 (en) 1999-03-22 2001-12-18 Scimed Life Systems, Inc. End sleeve coating for stent delivery
US6432141B1 (en) 1999-03-31 2002-08-13 Gregory W. Stocks Joint prosthesis assembly and method for installing same
SE515227C2 (en) 1999-04-28 2001-07-02 Bruce Medical Ab Body for providing and growing bone and / or connective tissue and methods for making the body
IT1307263B1 (en) 1999-08-05 2001-10-30 Sorin Biomedica Cardio Spa ANGIOPLASTIC STENT WITH RESTENOSIS ANTAGONIST ACTION, RELATED KIT AND COMPONENTS.
CN1378445B (en) 1999-08-06 2013-02-06 得克萨斯系统大学评议会 Drug releasing biodegradable fiber implant
US7220281B2 (en) 1999-08-18 2007-05-22 Intrinsic Therapeutics, Inc. Implant for reinforcing and annulus fibrosis
CA2425951C (en) 1999-08-18 2008-09-16 Intrinsic Therapeutics, Inc. Devices and method for nucleus pulposus augmentation and retention
US6425919B1 (en) 1999-08-18 2002-07-30 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6379381B1 (en) 1999-09-03 2002-04-30 Advanced Cardiovascular Systems, Inc. Porous prosthesis and a method of depositing substances into the pores
US6749626B1 (en) 2000-03-31 2004-06-15 Advanced Cardiovascular Systems, Inc. Actinomycin D for the treatment of vascular disease
US6713119B2 (en) 1999-09-03 2004-03-30 Advanced Cardiovascular Systems, Inc. Biocompatible coating for a prosthesis and a method of forming the same
US6503556B2 (en) 2000-12-28 2003-01-07 Advanced Cardiovascular Systems, Inc. Methods of forming a coating for a prosthesis
US6503954B1 (en) 2000-03-31 2003-01-07 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing actinomycin D and a method of forming the same
US6759054B2 (en) 1999-09-03 2004-07-06 Advanced Cardiovascular Systems, Inc. Ethylene vinyl alcohol composition and coating
US6287628B1 (en) 1999-09-03 2001-09-11 Advanced Cardiovascular Systems, Inc. Porous prosthesis and a method of depositing substances into the pores
US7682647B2 (en) 1999-09-03 2010-03-23 Advanced Cardiovascular Systems, Inc. Thermal treatment of a drug eluting implantable medical device
ES2213628T3 (en) 1999-10-29 2004-09-01 Drexel University ASSOCIATIVE HYDROGELS FOR THE REPLACEMENT OF THE PULP NUCLEUS IN INTERVERTEBRAL DISCS.
US6287291B1 (en) 1999-11-09 2001-09-11 Advanced Cardiovascular Systems, Inc. Protective sheath for catheters
US6476079B1 (en) 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
US6908624B2 (en) 1999-12-23 2005-06-21 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6379382B1 (en) * 2000-03-13 2002-04-30 Jun Yang Stent having cover with drug delivery capability
US20030229393A1 (en) 2001-03-15 2003-12-11 Kutryk Michael J. B. Medical device with coating that promotes cell adherence and differentiation
CN100506293C (en) 2000-03-15 2009-07-01 祥丰医疗有限公司 Coating that promotes endothelial Cell adherence
US7698111B2 (en) 2005-03-09 2010-04-13 Hewlett-Packard Development Company, L.P. Method and apparatus for computational analysis
US7279008B2 (en) 2000-03-16 2007-10-09 Smith & Nephew, Inc. Sheaths for implantable fixation devices
US6746483B1 (en) 2000-03-16 2004-06-08 Smith & Nephew, Inc. Sheaths for implantable fixation devices
AR027685A1 (en) 2000-03-22 2003-04-09 Synthes Ag METHOD AND METHOD FOR CARRYING OUT
US6818247B1 (en) 2000-03-31 2004-11-16 Advanced Cardiovascular Systems, Inc. Ethylene vinyl alcohol-dimethyl acetamide composition and a method of coating a stent
WO2001076514A2 (en) 2000-04-05 2001-10-18 Kyphon Inc. Methods and devices for treating fractured and/or diseased bone
US6520984B1 (en) 2000-04-28 2003-02-18 Cardiovasc, Inc. Stent graft assembly and method
US6451050B1 (en) * 2000-04-28 2002-09-17 Cardiovasc, Inc. Stent graft and method
US6299894B1 (en) 2000-05-10 2001-10-09 Leiras Oy Drug delivery device, especially for the delivery of gestodene
AU2004202878B2 (en) 2000-05-10 2005-12-01 Fisher & Paykel Healthcare Limited Components For Breathing Circuits
BR0102116B1 (en) 2000-05-10 2010-09-21 component for a breathing circuit member.
US6569180B1 (en) 2000-06-02 2003-05-27 Avantec Vascular Corporation Catheter having exchangeable balloon
US7238168B2 (en) 2000-06-02 2007-07-03 Avantec Vascular Corporation Exchangeable catheter
ATE415915T1 (en) 2000-07-14 2008-12-15 Kyphon Sarl DEVICES FOR TREATING VERTEBRATE BODY
US6451003B1 (en) 2000-08-16 2002-09-17 Biolink Corporation Method and apparatus for overcoming infection in a tissue pocket surrounding an implanted device
DE10041684A1 (en) 2000-08-24 2002-03-07 Inst Textil & Faserforschung Coating material for medical treatment from resorbable synthetic material, process for its production and use in medicine
US7503936B2 (en) 2000-08-30 2009-03-17 Warsaw Orthopedic, Inc. Methods for forming and retaining intervertebral disc implants
US6953560B1 (en) 2000-09-28 2005-10-11 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
US6716444B1 (en) 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
WO2002034148A2 (en) 2000-10-25 2002-05-02 Kyphon Inc. Systems and methods for reducing fractured bone using a fracture reduction cannula
US6692498B1 (en) 2000-11-27 2004-02-17 Linvatec Corporation Bioabsorbable, osteopromoting fixation plate
US6545097B2 (en) 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
US6599323B2 (en) 2000-12-21 2003-07-29 Ethicon, Inc. Reinforced tissue implants and methods of manufacture and use
US7192604B2 (en) 2000-12-22 2007-03-20 Ethicon, Inc. Implantable biodegradable devices for musculoskeletal repair or regeneration
KR100408458B1 (en) 2000-12-27 2003-12-06 한국과학기술연구원 Porous Scaffolds for Tissue Engineering made from the Biodegradable Glycolide/ε-Caprolactone Copolymer
US7504125B1 (en) 2001-04-27 2009-03-17 Advanced Cardiovascular Systems, Inc. System and method for coating implantable devices
US6547812B1 (en) 2000-12-29 2003-04-15 Advanced Cardiovascular Systems, Inc. Radiation therapy using a radioactive implantable device and a radiosensitizer agent
JP4840895B2 (en) 2001-02-20 2011-12-21 株式会社日本吸収体技術研究所 Liquid distribution unit and absorbent product comprising the same
US6827743B2 (en) 2001-02-28 2004-12-07 Sdgi Holdings, Inc. Woven orthopedic implants
NL1017672C2 (en) 2001-03-22 2002-09-24 Hendrik Glastra Implantable assembly with therapeutic effect.
US6899994B2 (en) 2001-04-04 2005-05-31 Kodak Polychrome Graphics Llc On-press developable IR sensitive printing plates using binder resins having polyethylene oxide segments
US20050209629A1 (en) 2001-04-19 2005-09-22 Kerr Sean H Resorbable containment device and process for making and using same
US6632235B2 (en) 2001-04-19 2003-10-14 Synthes (U.S.A.) Inflatable device and method for reducing fractures in bone and in treating the spine
WO2002096389A1 (en) 2001-05-30 2002-12-05 Microchips, Inc. Conformal coated microchip reservoir devices
US6592885B2 (en) 2001-06-07 2003-07-15 Matthew D. Phaneuf Method for making infection-resistant fabricated textile articles for biomedical applications
US6666880B1 (en) 2001-06-19 2003-12-23 Advised Cardiovascular Systems, Inc. Method and system for securing a coated stent to a balloon catheter
US7175873B1 (en) 2001-06-27 2007-02-13 Advanced Cardiovascular Systems, Inc. Rate limiting barriers for implantable devices and methods for fabrication thereof
US7247313B2 (en) 2001-06-27 2007-07-24 Advanced Cardiovascular Systems, Inc. Polyacrylates coatings for implantable medical devices
US20050129732A1 (en) 2001-07-13 2005-06-16 Flow Focusing, Inc. Biodegradable, antibiotic, controlled release tape
US20030050644A1 (en) 2001-09-11 2003-03-13 Boucher Ryan P. Systems and methods for accessing and treating diseased or fractured bone employing a guide wire
IN2014DN10834A (en) 2001-09-17 2015-09-04 Psivida Inc
US7168605B2 (en) 2001-09-18 2007-01-30 Boston Scientific Scimed, Inc. Microtubes for therapeutic delivery
CN2534997Y (en) 2001-09-21 2003-02-12 钱本文 Thigh-bone neck protection apparatus
US7425292B2 (en) 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
DE60229416D1 (en) 2001-10-25 2008-11-27 Univ Emory Catheter for modified perfusion
US20030093111A1 (en) * 2001-10-26 2003-05-15 Concentric Medical Device for vaso-occlusion and interventional therapy
US20030088307A1 (en) 2001-11-05 2003-05-08 Shulze John E. Potent coatings for stents
US7137993B2 (en) 2001-12-03 2006-11-21 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US7294146B2 (en) 2001-12-03 2007-11-13 Xtent, Inc. Apparatus and methods for delivery of variable length stents
US7309350B2 (en) 2001-12-03 2007-12-18 Xtent, Inc. Apparatus and methods for deployment of vascular prostheses
US7351255B2 (en) 2001-12-03 2008-04-01 Xtent, Inc. Stent delivery apparatus and method
US7182779B2 (en) 2001-12-03 2007-02-27 Xtent, Inc. Apparatus and methods for positioning prostheses for deployment from a catheter
US7270668B2 (en) 2001-12-03 2007-09-18 Xtent, Inc. Apparatus and methods for delivering coiled prostheses
US20030135266A1 (en) 2001-12-03 2003-07-17 Xtent, Inc. Apparatus and methods for delivery of multiple distributed stents
US7147656B2 (en) 2001-12-03 2006-12-12 Xtent, Inc. Apparatus and methods for delivery of braided prostheses
AU2002241676B2 (en) 2001-12-21 2008-10-23 Nfocus Neuromedical, Inc. Composite stent with polymeric covering and bioactive coating
US6863530B2 (en) 2001-12-28 2005-03-08 Incumed, Inc. Expandable polymer dental implant and method of use
US6840770B2 (en) 2001-12-28 2005-01-11 Mcdevitt Dennis Expandable polymer dental implant and method of use
US7070613B2 (en) 2002-01-04 2006-07-04 Boston Scientific Scimed, Inc. Non-compliant balloon with compliant top-layer to protect coated stents during expansion
EP1469794B1 (en) 2002-01-28 2009-03-18 OrbusNeich Medical, Inc. Flared ostial endoprosthesis and delivery system
US6790224B2 (en) * 2002-02-04 2004-09-14 Scimed Life Systems, Inc. Medical devices
EP1334702B1 (en) 2002-02-08 2004-07-07 Karl Storz GmbH & Co. KG Anchor element to anchor a ligament transplant
EP2522319A3 (en) * 2002-03-11 2013-09-25 Novartis AG Implantable drug delivery system
EP1344538A1 (en) 2002-03-14 2003-09-17 Degradable Solutions AG Porous biodegradable implant material and method for its fabrication
US7041308B2 (en) 2002-04-18 2006-05-09 Poly-Med, Inc. Drug-polymer coated stents with segmented homochain copolyesters
US6981991B2 (en) 2002-06-27 2006-01-03 Ferree Bret A Arthroplasty devices configured to reduce shear stress
US7622146B2 (en) 2002-07-18 2009-11-24 Advanced Cardiovascular Systems, Inc. Rate limiting barriers for implantable devices and methods for fabrication thereof
EP1545389B1 (en) 2002-07-31 2020-04-22 Mast Biosurgery AG Apparatus for preventing adhesions between an implant and surrounding tissues
US20050019404A1 (en) 2003-06-30 2005-01-27 Hsing-Wen Sung Drug-eluting biodegradable stent
CN1684725A (en) 2002-09-26 2005-10-19 血管技术国际股份公司 Perivascular wraps
US6863692B2 (en) 2002-11-14 2005-03-08 Zimmer Technology, Inc. Implant sleeve and method
US20040106199A1 (en) 2002-12-02 2004-06-03 Eliseev Alexey V. Charged cyclodextrin derivatives and their use in plant cell and tissue culture growth media
US7025791B2 (en) 2002-12-02 2006-04-11 Gi Dynamics, Inc. Bariatric sleeve
US7608114B2 (en) 2002-12-02 2009-10-27 Gi Dynamics, Inc. Bariatric sleeve
CA2512203C (en) 2002-12-02 2012-10-23 Gi Dynamics, Inc. Bariatric sleeve
US7678068B2 (en) 2002-12-02 2010-03-16 Gi Dynamics, Inc. Atraumatic delivery devices
US7695446B2 (en) 2002-12-02 2010-04-13 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US7766973B2 (en) 2005-01-19 2010-08-03 Gi Dynamics, Inc. Eversion resistant sleeves
US7491234B2 (en) 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
US7758881B2 (en) 2004-06-30 2010-07-20 Advanced Cardiovascular Systems, Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US7666216B2 (en) 2002-12-24 2010-02-23 Novostent Corporation Delivery catheter for ribbon-type prosthesis and methods of use
US7311727B2 (en) 2003-02-05 2007-12-25 Board Of Trustees Of The University Of Arkansas Encased stent
US20050107870A1 (en) 2003-04-08 2005-05-19 Xingwu Wang Medical device with multiple coating layers
US20040267347A1 (en) 2003-05-01 2004-12-30 Cervantes Marvin John Protective elongated sleeve for stent systems
CN1183051C (en) * 2003-06-04 2005-01-05 王胜怀 Polymer dry mixed mortar
US7931695B2 (en) 2003-07-15 2011-04-26 Kensey Nash Corporation Compliant osteosynthesis fixation plate
US7744620B2 (en) 2003-07-18 2010-06-29 Intervalve, Inc. Valvuloplasty catheter
US7169405B2 (en) 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
US7296998B2 (en) 2003-09-22 2007-11-20 Bartee Chaddick M Hydrophilic high density PTFE medical barrier
US7208008B2 (en) 2003-10-02 2007-04-24 Medtronic Vascular, Inc. Balloonless direct stenting device
US7618647B2 (en) 2003-10-03 2009-11-17 Boston Scientific Scimed, Inc. Using bucky paper as a therapeutic aid in medical applications
JP2007515974A (en) 2003-11-07 2007-06-21 ベイコ テック リミテッド Method for preparing drug-eluting medical device and medical device obtained by the method
CA2536042A1 (en) 2003-11-10 2005-06-02 Angiotech International Ag Medical implants and anti-scarring agents
US20090118817A1 (en) 2005-06-16 2009-05-07 Mayo Foundation For Medical Education And Research Magnetic Medical Apparatus, Kits, and Methods
US8465453B2 (en) 2003-12-03 2013-06-18 Mayo Foundation For Medical Education And Research Kits, apparatus and methods for magnetically coating medical devices with living cells
US7723395B2 (en) * 2004-04-29 2010-05-25 Kensey Nash Corporation Compressed porous materials suitable for implant
CA2549883A1 (en) 2003-12-15 2005-06-23 Technion Research & Development Foundation Ltd. Therapeutic drug-eluting endoluminal covering
US20050159805A1 (en) 2004-01-20 2005-07-21 Jan Weber Functional coatings and designs for medical implants
US20050272153A1 (en) 2004-01-27 2005-12-08 Zou Xuenong Bone tissue engineering by ex vivo stem cells ongrowth into three-dimensional trabecular metal
TWI434676B (en) 2004-03-19 2014-04-21 Merck Sharp & Dohme X-ray visible drug delivery device
WO2005094526A2 (en) 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US7465318B2 (en) 2004-04-15 2008-12-16 Soteira, Inc. Cement-directing orthopedic implants
US7578834B2 (en) 2004-05-03 2009-08-25 Abdou M S Devices and methods for the preservation of spinal prosthesis function
US7704545B2 (en) 2004-05-12 2010-04-27 Medtronic Vascular, Inc. Drug-polymer coated stent
US7758654B2 (en) 2004-05-20 2010-07-20 Kensey Nash Corporation Anti-adhesion device
US7785615B2 (en) 2004-05-28 2010-08-31 Cordis Corporation Biodegradable medical implant with encapsulated buffering agent
US20050278011A1 (en) 2004-06-10 2005-12-15 Peckham John E Stent delivery system
US20050288766A1 (en) 2004-06-28 2005-12-29 Xtent, Inc. Devices and methods for controlling expandable prostheses during deployment
US7402172B2 (en) 2004-10-13 2008-07-22 Boston Scientific Scimed, Inc. Intraluminal therapeutic patch
US20060093646A1 (en) 2004-10-28 2006-05-04 Cima Michael J Orthopedic and dental implant devices providing controlled drug delivery
US7771382B2 (en) 2005-01-19 2010-08-10 Gi Dynamics, Inc. Resistive anti-obesity devices
DE102005007596A1 (en) 2005-02-18 2006-08-24 Breeze Medical, Inc., Boca Raton Coating, manufacturing method and method for applying a coating to a medical instrument and medical instrument
EP1855625A2 (en) 2005-02-18 2007-11-21 Zimmer, Inc. Prosthetic hip stem with fully porous layer
TW200714289A (en) 2005-02-28 2007-04-16 Genentech Inc Treatment of bone disorders
EP1868527A4 (en) 2005-03-17 2009-12-30 Active Implants Corp Implant devices
DE102005017023A1 (en) 2005-04-13 2006-10-19 Bayer Materialscience Ag UV-stabilized polycarbonate moldings
US20070038299A1 (en) 2005-08-12 2007-02-15 Arthrotek, Inc Multilayer microperforated implant
US7789915B2 (en) 2005-08-31 2010-09-07 Vance Products Incorporated Stent for implantation
US7550012B2 (en) 2005-08-31 2009-06-23 Cook Ireland Limited Stent for implantation
CN101437571B (en) * 2005-10-13 2013-01-02 斯恩蒂斯有限公司 Drug-impregnated encasement
NL1030364C2 (en) 2005-11-07 2007-05-08 Ft Innovations Fti B V Implant and method for manufacturing such an implant.
US20070142892A1 (en) 2005-12-15 2007-06-21 Vipul Bhupendra Dave Self-expanding stent delivery system
US8048443B2 (en) 2005-12-16 2011-11-01 Cerapedics, Inc. Pliable medical device and method of use
ES2395112T3 (en) 2006-02-07 2013-02-08 Tepha, Inc. Cured polylactic acid polymers and copolymers
US8591531B2 (en) 2006-02-08 2013-11-26 Tyrx, Inc. Mesh pouches for implantable medical devices
MX2008010126A (en) 2006-02-08 2010-02-22 Tyrx Pharma Inc Temporarily stiffened mesh prostheses.
US8257419B2 (en) 2006-03-10 2012-09-04 Cordis Corporation Apparatus for treating a bifurcated region of a conduit
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
DK2004172T3 (en) 2006-03-31 2019-04-23 Mati Therapeutics Inc PHARMACEUTICAL ADMINISTRATION STRUCTURES AND COMPOSITIONS FOR NASOLACRIMAL SYSTEM
WO2007127295A2 (en) 2006-04-25 2007-11-08 Teleflex Medical Incorporated Calcium phosphate polymer composite and method
EP2010374B1 (en) 2006-04-27 2012-11-21 3M Innovative Properties Company Structured films having acoustical absorbance properties
US9468746B2 (en) 2006-08-22 2016-10-18 Medtronic Vascular, Inc. Systems and methods for local bioactive material delivery
US20080057096A1 (en) 2006-08-29 2008-03-06 Den-Mat Corporation Biocompatible stent
WO2008063157A2 (en) 2006-10-25 2008-05-29 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services A nanoparticle-based anticoagulant
US9023114B2 (en) 2006-11-06 2015-05-05 Tyrx, Inc. Resorbable pouches for implantable medical devices
US20080107711A1 (en) 2006-11-08 2008-05-08 Alexis Paul Shelokov Bioabsorbable Implantable Material Fortified with Antibiotics for Localized Delivery of Drugs
CA3013758C (en) 2006-11-22 2021-09-14 Inspiremd Ltd. Intravascular aneurysm treatment device and methods
GB0702864D0 (en) 2007-02-14 2007-03-28 Benoist Girard Sas Prosthetic implant for use without bone cement
JP2008224297A (en) 2007-03-09 2008-09-25 Hitachi High-Technologies Corp Autoanalyzer and small volume reagent container therefor
JP5400029B2 (en) 2007-03-29 2014-01-29 タイレックス・インコーポレイテッド Biodegradable polymer cover material for breast implants
US8430852B2 (en) 2007-04-17 2013-04-30 Medtronic, Inc. Therapeutic sleeve for implantable medical device
US9216101B2 (en) 2007-07-10 2015-12-22 Boston Scientific Scime, Inc. Dual taper stent protector
US9358113B2 (en) 2007-07-10 2016-06-07 Warsaw Orthopedic, Inc. Delivery system
US20090081276A1 (en) 2007-08-13 2009-03-26 Eben Alsberg Bioresorbable implant composition
US20090069904A1 (en) 2007-09-12 2009-03-12 Applied Medical Research Biomaterial including micropores
AR066166A1 (en) 2007-09-21 2009-07-29 Organon Nv DRUG SUPPLY SYSTEM
RU77539U1 (en) 2007-09-26 2008-10-27 Николай Алексеевич Алешин PLATE FOR MAXILLOFACIAL SURGERY
EP2052700A1 (en) 2007-09-26 2009-04-29 Microchips, Inc. Drug delivery device and method for use with prosthetic device implantation
US8192479B2 (en) 2007-11-30 2012-06-05 Cook Medical Technologies Llc Method and device for vascular therapy
EP2080603A1 (en) 2008-01-18 2009-07-22 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Manufacturing film or sheet material having openings
AU2008349523B2 (en) 2008-01-29 2013-10-24 Zimmer, Inc. Implant device for use in an implant system
WO2009111716A1 (en) 2008-03-06 2009-09-11 Boston Scientific Scimed, Inc. Balloon catheter devices with sheath covering
CN101587099B (en) 2008-05-21 2012-03-28 鸿富锦精密工业（深圳）有限公司 Method for manufacturing surface acoustic wave sensor
KR20110056539A (en) 2008-09-10 2011-05-30 이브이쓰리 인크. Stents and catheters having improved stent deployment
CN101402736A (en) 2008-11-12 2009-04-08 华中科技大学 Biodegradable unsaturated polyphosphate, preparation and use method thereof
FR2941616B1 (en) 2009-01-30 2012-06-08 T H T Textile Hi Tec IMPLANTABLE PLATE FOR THE REFLECTION OF WALLS
US20120010636A1 (en) 2009-02-11 2012-01-12 Nanyang Technological University Multi-layered surgical prosthesis
US9339630B2 (en) 2009-02-19 2016-05-17 Medtronic Vascular, Inc. Retractable drug delivery system and method
US20100228333A1 (en) 2009-03-04 2010-09-09 William Joseph Drasler Drug eluting surface covering
US20100249783A1 (en) 2009-03-24 2010-09-30 Warsaw Orthopedic, Inc. Drug-eluting implant cover
US20100247600A1 (en) 2009-03-24 2010-09-30 Warsaw Orthopedic, Inc. Therapeutic drug eluting implant cover and method of making the same
US8888847B2 (en) 2009-05-22 2014-11-18 Medtronic, Inc. Cover having self-anchoring protrusions for use with an implantable medical device
US9504771B2 (en) 2009-11-09 2016-11-29 W. L. Gore & Associates, Inc. Drug eluting composite
JP2011216178A (en) 2010-03-18 2011-10-27 Panasonic Corp Reproducing device, reproducing system, and server
JP2011207847A (en) 2010-03-30 2011-10-20 Nitto Denko Corp Film-form preparation and method for producing the same
AU2011288209C1 (en) 2010-04-28 2016-03-24 Kimberly-Clark Worldwide, Inc. Injection molded microneedle array and method for forming the microneedle array
US8697117B2 (en) 2010-08-02 2014-04-15 Ramot At Tel-Aviv University Ltd. Drug-eluting films
JP2013535485A (en) 2010-08-02 2013-09-12 ユークリッド システムズ コーポレイション Collagen-based implants for sustained drug delivery
CN101912663B (en) 2010-08-18 2013-09-04 清华大学 Empty micropin array chip, percutaneous dosing paster, device and manufacture method thereof
JP2013005984A (en) 2011-06-27 2013-01-10 Kyocera Medical Corp Bone plate
CA2842550C (en) 2011-07-20 2020-03-24 Patrick F. Kiser Intravaginal devices for drug delivery
TWI590843B (en) 2011-12-28 2017-07-11 信迪思有限公司 Films and methods of manufacture

Also Published As

Publication number Publication date
US20180085564A1 (en) 2018-03-29
EP3566742A1 (en) 2019-11-13
US9579260B2 (en) 2017-02-28
ZA200803822B (en) 2010-01-27
BRPI0617325B1 (en) 2020-09-15
JP5676541B2 (en) 2015-02-25
CN103251449A (en) 2013-08-21
EP1933936B1 (en) 2019-03-20
EP1933936A4 (en) 2010-05-12
CN103251449B (en) 2016-03-02
BRPI0617325B8 (en) 2021-06-22
CA2625264C (en) 2015-12-15
BRPI0617325A2 (en) 2011-07-19
US20130289621A1 (en) 2013-10-31
CN101437571A (en) 2009-05-20
KR101420988B1 (en) 2014-07-17
US20170136223A1 (en) 2017-05-18
US20080262630A1 (en) 2008-10-23
KR101377900B1 (en) 2014-03-27
JP5893672B2 (en) 2016-03-23
CN101437571B (en) 2013-01-02
JP2014147842A (en) 2014-08-21
WO2007047420A2 (en) 2007-04-26
CA2625264A1 (en) 2007-05-26
US10814112B2 (en) 2020-10-27
EP1933936A2 (en) 2008-06-25
JP2009511196A (en) 2009-03-19
AU2006304229A1 (en) 2007-04-26
US20210031013A1 (en) 2021-02-04
US8900620B2 (en) 2014-12-02
KR20130048272A (en) 2013-05-09
KR20080068699A (en) 2008-07-23
JP2012250084A (en) 2012-12-20
WO2007047420A3 (en) 2007-12-06
US20150018969A1 (en) 2015-01-15
JP5137841B2 (en) 2013-02-06

Similar Documents

Publication Publication Date Title
WO2007047420A3 (en) Drug-impregnated encasement
WO2006097932A3 (en) Implant devices
WO2006017396A3 (en) Tissue repair device with a bioabsorbable support member
EP2586385A3 (en) Structure for pemanent occlusion of a hollow anatomical structure
WO2005120400A3 (en) Methods and apparatuses for bone restoration
WO2006096793A3 (en) Medical implants
WO2008008831A3 (en) Orthopedic implants comprising bioabsorbable metal
WO2010099333A3 (en) Bone graft material containment structures
ATE527963T1 (en) MINIMALLY INVASIVE MEDICAL IMPLANT AND INTRODUCER DEVICE
WO2006047310A3 (en) Hollow and porous orthopaedic or dental implant that delivers a biological agent
CA2471890A1 (en) Implantable prosthesis
WO2007046955A3 (en) Devices, systems, and methods for prosthesis delivery and implantation
WO2008121816A3 (en) Biodegradable, polymer coverings for breast implants
WO2004066867A3 (en) Solid implant
CA2660287A1 (en) Medical device for repair of tissue and method for implantation and fixation
WO2005110050A3 (en) Tissue scaffold
CA2540450A1 (en) Penile prosthesis devices
WO2005018435A3 (en) Thermally modified microbial-derived cellulose for in vivo implantation
WO2005011770A3 (en) Biologically absorbable coatings for implantable devices
MXPA03003906A (en) Surgically implanted devices having reduced scar tissue.
CA2609706A1 (en) Implantable graft to close a fistula
WO2007134134A3 (en) Reinforced biological tissue
ZA200606520B (en) Implant that can be implanted in osseous tissue, method for producing said implant and corresponding implant
EP2572683A3 (en) Deployment system for an endoluminal device
WO2006126201A3 (en) Suture loops for implantable device

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200680037881.8

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2006816850

Country of ref document: EP

DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
ENP Entry into the national phase

Ref document number: 2625264

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 12089574

Country of ref document: US

ENP Entry into the national phase

Ref document number: 2008535700

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 567452

Country of ref document: NZ

WWE Wipo information: entry into national phase

Ref document number: 2006304229

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 1720/KOLNP/2008

Country of ref document: IN

ENP Entry into the national phase

Ref document number: 2006304229

Country of ref document: AU

Date of ref document: 20061012

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 08048347

Country of ref document: CO

Ref document number: 1020087011335

Country of ref document: KR

ENP Entry into the national phase

Ref document number: PI0617325

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20080411

DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 1020137008793

Country of ref document: KR