WO2007017846A8 - Localization of a radioactive source - Google Patents

Localization of a radioactive source

Info

Publication number
WO2007017846A8
WO2007017846A8 PCT/IB2006/052770 IB2006052770W WO2007017846A8 WO 2007017846 A8 WO2007017846 A8 WO 2007017846A8 IB 2006052770 W IB2006052770 W IB 2006052770W WO 2007017846 A8 WO2007017846 A8 WO 2007017846A8
Authority
WO
WIPO (PCT)
Prior art keywords
detector
radiation
relative orientation
working volume
localization
Prior art date
Application number
PCT/IB2006/052770
Other languages
French (fr)
Other versions
WO2007017846A2 (en
WO2007017846A3 (en
Inventor
David Maier Neustadter
Giora Kornblau
Original Assignee
Navotek Medical Ltd
David Maier Neustadter
Giora Kornblau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IL2005/000871 external-priority patent/WO2006016368A2/en
Application filed by Navotek Medical Ltd, David Maier Neustadter, Giora Kornblau filed Critical Navotek Medical Ltd
Priority to EP06795628A priority Critical patent/EP1922011B1/en
Priority to US11/990,315 priority patent/US7952079B2/en
Priority to AT06795628T priority patent/ATE555737T1/en
Priority to US11/791,890 priority patent/US20090131734A1/en
Publication of WO2007017846A2 publication Critical patent/WO2007017846A2/en
Priority to PCT/IL2007/000215 priority patent/WO2007094002A2/en
Priority to PCT/IL2007/000214 priority patent/WO2007094001A2/en
Priority to EP07706152A priority patent/EP1988844B1/en
Publication of WO2007017846A3 publication Critical patent/WO2007017846A3/en
Publication of WO2007017846A8 publication Critical patent/WO2007017846A8/en
Priority to IL189442A priority patent/IL189442A/en
Priority to IL193412A priority patent/IL193412A0/en
Priority to IL209161A priority patent/IL209161A0/en
Priority to IL209158A priority patent/IL209158A0/en
Priority to IL209159A priority patent/IL209159A0/en
Priority to IL209160A priority patent/IL209160A0/en
Priority to US13/091,775 priority patent/US8198600B2/en
Priority to US13/347,503 priority patent/US20120323117A1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/29Measurement performed on radiation beams, e.g. position or section of the beam; Measurement of spatial distribution of radiation
    • G01T1/2907Angle determination; Directional detectors; Telescopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/42Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4258Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector for detecting non x-ray radiation, e.g. gamma radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/101Computer-aided simulation of surgical operations
    • A61B2034/105Modelling of the patient, e.g. for ligaments or bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046Tracking techniques
    • A61B2034/2051Electromagnetic tracking systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2068Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis using pointers, e.g. pointers having reference marks for determining coordinates of body points
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B2090/101Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis for stereotaxic radiosurgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/392Radioactive markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1126Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb using a particular sensing technique
    • A61B5/1127Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb using a particular sensing technique using markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Robotics (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nuclear Medicine (AREA)
  • Length-Measuring Devices Using Wave Or Particle Radiation (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

An angle-responsive sensor, comprising: a radiation detector adapted to detect ionizing radiation; at least one radiation absorbing element arranged to block radiation from reaching said detector in a manner dependent on a relative orientation of a radiation source, said detector and said element, said detector and said element defining an aim for said sensor; and circuitry coupled to said detector and which generates an output signal which varies as a function of said relative orientation, wherein said detector and said element are arranged to have a working volume of at least 10 cm in depth and having an angular width, such that said signal defines an accuracy of better than 3 mm within one standard deviation, over said working volume.
PCT/IB2006/052770 2004-08-12 2006-08-10 Localization of a radioactive source WO2007017846A2 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
EP06795628A EP1922011B1 (en) 2005-08-11 2006-08-10 Localization of a radioactive source
US11/990,315 US7952079B2 (en) 2004-08-12 2006-08-10 Localization of a radioactive source
AT06795628T ATE555737T1 (en) 2005-08-11 2006-08-10 LOCALIZATION OF A RADIOACTIVE SOURCE
EP07706152A EP1988844B1 (en) 2006-02-16 2007-02-15 Implantable medical marker and methods of preparation thereof
PCT/IL2007/000214 WO2007094001A2 (en) 2006-02-16 2007-02-15 Implantable medical marker and methods of preparation thereof
US11/791,890 US20090131734A1 (en) 2006-02-16 2007-02-15 Implantable medical marker and methods of preparation thereof
PCT/IL2007/000215 WO2007094002A2 (en) 2006-02-16 2007-02-15 Location indication by pointing to an intrabody radiation source
IL189442A IL189442A (en) 2005-08-11 2008-02-11 Localization of a radioactive source
IL193412A IL193412A0 (en) 2006-02-16 2008-08-12 Implantable medical marker and methods of preparation thereof
IL209161A IL209161A0 (en) 2005-08-11 2010-11-04 Localization of a radioactive source
IL209160A IL209160A0 (en) 2005-08-11 2010-11-04 Localization of a radioactive source
IL209159A IL209159A0 (en) 2005-08-11 2010-11-04 Localization of a radioactive source
IL209158A IL209158A0 (en) 2005-08-11 2010-11-04 Localization of a radioactive source
US13/091,775 US8198600B2 (en) 2004-08-12 2011-04-21 Localization of a radioactive source
US13/347,503 US20120323117A1 (en) 2006-02-16 2012-01-10 Implantable Medical Marker and Methods of Preparation Thereof

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
ILPCT/IL2005/000871 2005-08-11
PCT/IL2005/000871 WO2006016368A2 (en) 2004-08-12 2005-08-11 Localization of a radioactive source within a body of a subject
US77393006P 2006-02-16 2006-02-16
US77393106P 2006-02-16 2006-02-16
US60/773,931 2006-02-16
US60/773,930 2006-02-16
US80417806P 2006-06-08 2006-06-08
US60/804,178 2006-06-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2005/000871 Continuation-In-Part WO2006016368A2 (en) 2004-08-12 2005-08-11 Localization of a radioactive source within a body of a subject

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US11/990,315 A-371-Of-International US7952079B2 (en) 2004-08-12 2006-08-10 Localization of a radioactive source
PCT/IB2006/052771 Continuation-In-Part WO2007017847A1 (en) 2004-08-12 2006-08-10 Medical treatment system and method using radioactivity based position sensor
US13/091,775 Division US8198600B2 (en) 2004-08-12 2011-04-21 Localization of a radioactive source

Publications (3)

Publication Number Publication Date
WO2007017846A2 WO2007017846A2 (en) 2007-02-15
WO2007017846A3 WO2007017846A3 (en) 2007-09-07
WO2007017846A8 true WO2007017846A8 (en) 2007-11-29

Family

ID=37500052

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/052770 WO2007017846A2 (en) 2004-08-12 2006-08-10 Localization of a radioactive source

Country Status (3)

Country Link
US (2) US7952079B2 (en)
EP (1) EP1922011B1 (en)
WO (1) WO2007017846A2 (en)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7963695B2 (en) 2002-07-23 2011-06-21 Rapiscan Systems, Inc. Rotatable boom cargo scanning system
US8275091B2 (en) 2002-07-23 2012-09-25 Rapiscan Systems, Inc. Compact mobile cargo scanning system
US6928141B2 (en) 2003-06-20 2005-08-09 Rapiscan, Inc. Relocatable X-ray imaging system and method for inspecting commercial vehicles and cargo containers
WO2006043276A2 (en) * 2004-10-19 2006-04-27 Navotek Medical Ltd. Locating a catheter tip using a tracked guide
EP1805506A4 (en) 2004-08-12 2010-06-02 Navotek Medical Ltd Localization of a radioactive source within a body of a subject
US7471764B2 (en) 2005-04-15 2008-12-30 Rapiscan Security Products, Inc. X-ray imaging system having improved weather resistance
EP1922011B1 (en) * 2005-08-11 2012-05-02 Navotek Medical Ltd. Localization of a radioactive source
BRPI0616514A2 (en) * 2005-08-11 2011-06-21 Navotek Medical Ltd medical treatment system and method using position sensor based radioactivity
EP1922113A1 (en) * 2005-08-11 2008-05-21 Navotek Medical Ltd. Medical treatment system and method using radioactivity based position sensor
US7526064B2 (en) 2006-05-05 2009-04-28 Rapiscan Security Products, Inc. Multiple pass cargo inspection system
US8035091B2 (en) * 2007-05-11 2011-10-11 Microsemi Corporation Passive outdoor millimeter wave illuminator
US8295910B1 (en) * 2007-11-16 2012-10-23 Jefferson Science Associates, Llc Imaging method for monitoring delivery of high dose rate brachytherapy
US8017915B2 (en) 2008-03-14 2011-09-13 Reflexion Medical, Inc. Method and apparatus for emission guided radiation therapy
WO2009128062A2 (en) * 2008-04-15 2009-10-22 Navotek Medical Ltd. Hybrid medical device localization system
GB0809110D0 (en) 2008-05-20 2008-06-25 Rapiscan Security Products Inc Gantry scanner systems
US8963094B2 (en) 2008-06-11 2015-02-24 Rapiscan Systems, Inc. Composite gamma-neutron detection system
GB0810638D0 (en) * 2008-06-11 2008-07-16 Rapiscan Security Products Inc Photomultiplier and detection systems
US8260567B1 (en) * 2008-09-19 2012-09-04 The United States Of America, As Represented By The Secretary Of The Navy System and method for angles-only position and velocity determination using closed-form triangulation
US9310323B2 (en) 2009-05-16 2016-04-12 Rapiscan Systems, Inc. Systems and methods for high-Z threat alarm resolution
US8498689B2 (en) * 2009-11-04 2013-07-30 International Business Machines Corporation Real time motion information capture in an MRI environment
GB2490061B (en) * 2009-12-22 2017-03-22 Rapiscan Systems Inc Composite gamma-neutron detection system
WO2012050742A1 (en) * 2010-10-15 2012-04-19 American Science And Engineering, Inc. Remotely-aligned arcuate detector array for high energy x-ray imaging
ES2938411T3 (en) 2011-02-08 2023-04-10 Rapiscan Systems Inc Covert surveillance using multimodality detection
US9218933B2 (en) 2011-06-09 2015-12-22 Rapidscan Systems, Inc. Low-dose radiographic imaging system
MX2014002728A (en) 2011-09-07 2014-08-22 Rapiscan Systems Inc X-ray inspection system that integrates manifest data with imaging/detection processing.
JP2013116138A (en) * 2011-12-01 2013-06-13 Sony Corp Image processing apparatus and method
JP6328110B2 (en) * 2012-07-17 2018-05-23 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. Determination device for determining the orientation and shape of an introduction element
US9791590B2 (en) 2013-01-31 2017-10-17 Rapiscan Systems, Inc. Portable security inspection system
US9592018B2 (en) * 2013-02-19 2017-03-14 Boston Scientific Scimed, Inc. Devices and methods for minimally invasive reduction of parathyroid adenomas
CN105637350A (en) 2013-07-23 2016-06-01 拉皮斯坎系统股份有限公司 Methods for improving processing speed for object inspection
US9557427B2 (en) 2014-01-08 2017-01-31 Rapiscan Systems, Inc. Thin gap chamber neutron detectors
US9599697B2 (en) 2014-04-15 2017-03-21 The Johns Hopkins University Non-contact fiber optic localization and tracking system
US9587951B1 (en) * 2014-06-15 2017-03-07 Qatar University Qstp-B Map matching methods and system for tracking and determining improved position of reference assets
WO2016003547A1 (en) 2014-06-30 2016-01-07 American Science And Engineering, Inc. Rapidly relocatable modular cargo container scanner
US10345479B2 (en) 2015-09-16 2019-07-09 Rapiscan Systems, Inc. Portable X-ray scanner
CN116309260A (en) 2016-02-22 2023-06-23 拉皮斯坎系统股份有限公司 Method for evaluating average pallet size and density of goods
CA3026133A1 (en) 2016-05-31 2017-12-07 David W. Holdsworth Ugamma probe and multimodal intraoperative imaging system
EP3541287A4 (en) 2016-11-15 2020-09-30 RefleXion Medical, Inc. Radiation therapy patient platform
WO2018093933A1 (en) 2016-11-15 2018-05-24 Reflexion Medical, Inc. System for emission-guided high-energy photon delivery
US10600609B2 (en) 2017-01-31 2020-03-24 Rapiscan Systems, Inc. High-power X-ray sources and methods of operation
WO2018183748A1 (en) 2017-03-30 2018-10-04 Reflexion Medical, Inc. Radiation therapy systems and methods with tumor tracking
US10024985B1 (en) 2017-05-02 2018-07-17 David Edward Newman Gamma ray detector with two-dimensional directionality
US9864074B1 (en) 2017-05-15 2018-01-09 David Edward Newman Directional particle detector with shield and scintillators
EP3651851B1 (en) 2017-07-11 2023-11-08 RefleXion Medical, Inc. Methods for pet detector afterglow management
EP3664712A4 (en) 2017-08-09 2021-05-05 RefleXion Medical, Inc. Systems and methods for fault detection in emission-guided radiotherapy
US10101472B1 (en) 2017-10-08 2018-10-16 David Edward Newman Radiation detector with two-dimensional directionality
US11369806B2 (en) 2017-11-14 2022-06-28 Reflexion Medical, Inc. Systems and methods for patient monitoring for radiotherapy
US10401506B1 (en) 2017-11-19 2019-09-03 David Edward Newman System for detecting and locating radioactive sources
US10444385B1 (en) 2018-08-01 2019-10-15 David Edward Newman Shieldless detector with one-dimensional directionality
US10330804B1 (en) 2018-02-04 2019-06-25 David Edward Newman One-dimensional directional particle detector
US10416322B1 (en) 2018-02-04 2019-09-17 David Edward Newman One-dimensional directional shieldless particle detector
US10605932B1 (en) 2018-04-22 2020-03-31 David Edward Newman Compact directional radiation detector system
US11819286B2 (en) * 2018-06-25 2023-11-21 Mirion Technologies (Canberra) Sas Apparatus for visualizing a movable radiation source
US10416318B1 (en) * 2018-08-31 2019-09-17 David Edward Newman Detector array for locating radioactive sources in three dimensions
US10261200B1 (en) 2018-11-12 2019-04-16 David Edward Newman Cylindrical directional detector without collimator
CN109431624B (en) * 2018-12-12 2020-09-08 日照市中医医院 Neurosurgery is clinical with brain operation auxiliary assembly
US11212902B2 (en) 2020-02-25 2021-12-28 Rapiscan Systems, Inc. Multiplexed drive systems and methods for a multi-emitter X-ray source
US11193898B1 (en) 2020-06-01 2021-12-07 American Science And Engineering, Inc. Systems and methods for controlling image contrast in an X-ray system
WO2022183191A1 (en) 2021-02-23 2022-09-01 Rapiscan Systems, Inc. Systems and methods for eliminating cross-talk in scanning systems having multiple x-ray sources
CN113408688B (en) * 2021-06-29 2022-06-07 哈尔滨工业大学 Unknown environment-oriented multi-radioactive source online searching method

Family Cites Families (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1561351A (en) * 1968-01-30 1969-03-28
US3777148A (en) * 1970-06-22 1973-12-04 Univ Case Western Reserve Collimator
US3794840A (en) * 1972-03-27 1974-02-26 Charlotte Memorial Hospital Method and apparatus for directing a radiation beam toward a tumor or the like
US3951550A (en) * 1974-08-12 1976-04-20 The Magnavox Company Direction-sensing virtual aperture radiation detector
DE2544354A1 (en) * 1975-10-03 1977-04-14 Siemens Ag METHOD OF DETERMINING THE DENSITY OF BODIES BY MEANS OF PENETRATING RAYS AND EQUIPMENT FOR ITS IMPLEMENTATION
US4096862A (en) * 1976-05-17 1978-06-27 Deluca Salvatore A Locating of tubes in the human body
FR2399033A1 (en) 1977-07-29 1979-02-23 Thomson Csf DEVICE FOR LOCATING A RADIANT SOURCE AND DIRECTION TRACKING SYSTEM INCLUDING SUCH A DEVICE
US4209700A (en) * 1977-12-30 1980-06-24 Union Carbide Corporation Nuclear transverse sectional brain function imager
US4215694A (en) * 1978-06-01 1980-08-05 Isakov Viktor L Laser therapy apparatus
US4243652A (en) * 1978-07-14 1981-01-06 The Procter & Gamble Company Gastrointestinal scanning agent
US4250392A (en) * 1979-02-27 1981-02-10 Engineering Dynamics Corporation Bi-focal collimator
US4782840A (en) 1984-03-02 1988-11-08 Neoprobe Corporation Method for locating, differentiating, and removing neoplasms
US4636380A (en) 1984-04-23 1987-01-13 Wong Dennis W Novel physiologic chemical method of labeling protein substances with the radionuclides of indium
US4755680A (en) * 1984-04-27 1988-07-05 The Curators Of The University Of Missouri Radiation imaging apparatus and methods
GB8627878D0 (en) 1986-11-21 1998-11-25 Barr & Stroud Ltd Detecting apparatus
US4820924A (en) * 1986-12-19 1989-04-11 Siemens Gammasonics, Inc. Scintillation camera and three dimensional multifocal collimator used therewith
US4944754A (en) * 1987-04-29 1990-07-31 Vent-Plant Corporation Method of manufacturing synthetic bone coated surgical implants
US4857729A (en) * 1988-04-22 1989-08-15 Halliburton Logging Services, Inc. Method of radioactive well logging
DE3841401A1 (en) * 1988-12-08 1990-06-13 Martin Lemperle ALLOPLASTIC IMPLANT
US4959547A (en) * 1989-06-08 1990-09-25 Care Wise Medical Products Corporation Apparatus and methods for detecting, localizing, and imaging of radiation in biological systems
US5114401A (en) * 1990-02-23 1992-05-19 New England Deaconess Hospital Corporation Method for central venous catheterization
AT397468B (en) 1990-07-11 1994-04-25 Oesterr Forsch Seibersdorf SPOTLIGHT HOLDER AND METHOD AND DEVICE FOR PRODUCING THE SAME
US5170055A (en) 1990-07-25 1992-12-08 Care Wise Medical Products Corporation Radiation detecting biopsy probe
US5342283A (en) * 1990-08-13 1994-08-30 Good Roger R Endocurietherapy
US5207223A (en) * 1990-10-19 1993-05-04 Accuray, Inc. Apparatus for and method of performing stereotaxic surgery
US5662111A (en) * 1991-01-28 1997-09-02 Cosman; Eric R. Process of stereotactic optical navigation
EP0531081A1 (en) 1991-09-03 1993-03-10 General Electric Company Tracking system to follow the position and orientation of a device with radiofrequency fields
US5211165A (en) 1991-09-03 1993-05-18 General Electric Company Tracking system to follow the position and orientation of a device with radiofrequency field gradients
US6537574B1 (en) * 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US5345084A (en) * 1993-03-29 1994-09-06 The United States Of America As Represented By The United States Department Of Energy Directional fast-neutron detector
FR2706043B1 (en) * 1993-06-02 1995-07-07 Commissariat Energie Atomique Installation and method for reconstructing three-dimensional images.
US6285898B1 (en) * 1993-07-20 2001-09-04 Biosense, Inc. Cardiac electromechanics
US5558091A (en) * 1993-10-06 1996-09-24 Biosense, Inc. Magnetic determination of position and orientation
US5707332A (en) * 1994-01-21 1998-01-13 The Trustees Of Columbia University In The City Of New York Apparatus and method to reduce restenosis after arterial intervention
US5460592A (en) * 1994-01-24 1995-10-24 Amersham Holdings, Inc. Apparatus and method for making carrier assembly for radioactive seed carrier
US5740808A (en) * 1996-10-28 1998-04-21 Ep Technologies, Inc Systems and methods for guilding diagnostic or therapeutic devices in interior tissue regions
US6033721A (en) * 1994-10-26 2000-03-07 Revise, Inc. Image-based three-axis positioner for laser direct write microchemical reaction
US6690963B2 (en) * 1995-01-24 2004-02-10 Biosense, Inc. System for determining the location and orientation of an invasive medical instrument
US5694933A (en) * 1995-04-28 1997-12-09 Care Wise Medical Products Corporation Apparatus and methods for determining spatial coordinates of radiolabelled tissue using gamma-rays and associated characteristic X-rays
US5813985A (en) * 1995-07-31 1998-09-29 Care Wise Medical Products Corporation Apparatus and methods for providing attenuation guidance and tumor targeting for external beam radiation therapy administration
US5713828A (en) * 1995-11-27 1998-02-03 International Brachytherapy S.A Hollow-tube brachytherapy device
IL125761A (en) * 1996-02-15 2005-05-17 Biosense Inc Independently positionable transducers for location system
AU709081B2 (en) * 1996-02-15 1999-08-19 Biosense, Inc. Medical procedures and apparatus using intrabody probes
US5961457A (en) * 1996-05-03 1999-10-05 The Regents Of The University Of Michigan Method and apparatus for radiopharmaceutical-guided biopsy
US6068623A (en) * 1997-03-06 2000-05-30 Percusurge, Inc. Hollow medical wires and methods of constructing same
DE69731322T2 (en) * 1996-06-11 2005-03-17 Roke Manor Research Ltd., Romsey A catheter tracking system
US5665970A (en) * 1996-07-03 1997-09-09 The United States Of America As Represented By The Secretary Of The Army Directional radiation detector and imager
US6016439A (en) * 1996-10-15 2000-01-18 Biosense, Inc. Method and apparatus for synthetic viewpoint imaging
US6380732B1 (en) * 1997-02-13 2002-04-30 Super Dimension Ltd. Six-degree of freedom tracking system having a passive transponder on the object being tracked
US6580938B1 (en) * 1997-02-25 2003-06-17 Biosense, Inc. Image-guided thoracic therapy and apparatus therefor
US5961451A (en) 1997-04-07 1999-10-05 Motorola, Inc. Noninvasive apparatus having a retaining member to retain a removable biosensor
US5846513B1 (en) * 1997-07-08 2000-11-28 Carewise Medical Products Corp Tumor localization and removal system using penetratable detection probe and removal instrument
US6018439A (en) * 1997-09-05 2000-01-25 Seagate Technology, Inc. Connector assembly for connecting transducing heads to a flex circuit of a disc drive
US5987350A (en) 1997-10-10 1999-11-16 Neoprobe Corporation Surgical probe apparatus and system
US6419621B1 (en) * 1997-10-24 2002-07-16 Radiomed Corporation Coiled brachytherapy device
US7066924B1 (en) * 1997-11-12 2006-06-27 Stereotaxis, Inc. Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip
US5961458A (en) * 1997-11-18 1999-10-05 Carewise Medical Products Corporation Minimally invasive surgical probe for tissue identification and retrieval and method of use
IL122578A (en) * 1997-12-12 2000-08-13 Super Dimension Ltd Wireless six-degree-of-freedom locator
GB2335744A (en) * 1998-03-27 1999-09-29 Intravascular Res Ltd Medical ultrasonic imaging
EP2289423A1 (en) 1998-05-14 2011-03-02 David N. Krag System for bracketing tissue
US6363940B1 (en) * 1998-05-14 2002-04-02 Calypso Medical Technologies, Inc. System and method for bracketing and removing tissue
JP2003524443A (en) * 1998-08-02 2003-08-19 スーパー ディメンション リミテッド Medical guidance device
EP1115328A4 (en) * 1998-09-24 2004-11-10 Super Dimension Ltd System and method for determining the location of a catheter during an intra-body medical procedure
US6496717B2 (en) * 1998-10-06 2002-12-17 University Of South Florida Radio guided seed localization of imaged lesions
US6056700A (en) * 1998-10-13 2000-05-02 Emx, Inc. Biopsy marker assembly and method of use
DE69931006T2 (en) 1998-10-14 2007-01-04 Terumo K.K. Wired radiation source and catheter assembly for radiotherapy
US6937696B1 (en) 1998-10-23 2005-08-30 Varian Medical Systems Technologies, Inc. Method and system for predictive physiological gating
US6100530A (en) * 1998-11-23 2000-08-08 The United States Of America As Represented By The Secretary Of The Army Angular time synchronized directional radiation sensor
US6371904B1 (en) * 1998-12-24 2002-04-16 Vivant Medical, Inc. Subcutaneous cavity marking device and method
US6230038B1 (en) * 1999-02-01 2001-05-08 International Business Machines Corporation Imaging of internal structures of living bodies by sensing implanted magnetic devices
US7983734B2 (en) * 2003-05-23 2011-07-19 Senorx, Inc. Fibrous marker and intracorporeal delivery thereof
US6725083B1 (en) * 1999-02-02 2004-04-20 Senorx, Inc. Tissue site markers for in VIVO imaging
US7575550B1 (en) 1999-03-11 2009-08-18 Biosense, Inc. Position sensing based on ultrasound emission
US6263940B1 (en) * 1999-04-21 2001-07-24 Axon Corporation In-line continuous feed sleeve labeling machine and method
US6696686B1 (en) * 1999-06-06 2004-02-24 Elgems Ltd. SPECT for breast cancer detection
DE69930568T2 (en) 1999-06-18 2006-11-09 Aea Technology Qsa Gmbh Radiation source for endovascular irradiation
FR2795526B1 (en) * 1999-06-22 2001-11-23 Jean Maublant DEVICE FOR DETECTING AND LOCATING A RADIOACTIVE SOURCE EMITTING GAMMA RADIATION, USE OF SAID DEVICE
US6264599B1 (en) * 1999-08-10 2001-07-24 Syntheon, Llc Radioactive therapeutic seeds having fixation structure
US6436026B1 (en) * 1999-10-22 2002-08-20 Radiomed Corporation Flexible, continuous, axially elastic interstitial brachytherapy source
US6402677B1 (en) * 1999-12-17 2002-06-11 C.R. Bard, Inc. Brachytherapy seed needle with window
US6510336B1 (en) * 2000-03-03 2003-01-21 Intra Medical Imaging, Llc Methods and devices to expand applications of intraoperative radiation probes
US6535756B1 (en) * 2000-04-07 2003-03-18 Surgical Navigation Technologies, Inc. Trajectory storage apparatus and method for surgical navigation system
US6455856B1 (en) 2000-06-02 2002-09-24 Koninklijke Philips Electronics N.V. Gamma camera gantry and imaging method
DE10033723C1 (en) * 2000-07-12 2002-02-21 Siemens Ag Surgical instrument position and orientation visualization device for surgical operation has data representing instrument position and orientation projected onto surface of patient's body
US7826889B2 (en) * 2000-08-21 2010-11-02 Spectrum Dynamics Llc Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
WO2002016965A2 (en) * 2000-08-21 2002-02-28 V-Target Technologies Ltd. Radioactive emission detector
US8909325B2 (en) 2000-08-21 2014-12-09 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US8565860B2 (en) 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
US6603123B1 (en) * 2000-11-08 2003-08-05 Koninklijke Philips Electronics, N.V. Correction for depth-dependent sensitivity in rotating slat-collimated gamma camera
US6746661B2 (en) * 2000-11-16 2004-06-08 Microspherix Llc Brachytherapy seed
ATE456332T1 (en) 2000-11-17 2010-02-15 Calypso Medical Inc SYSTEM FOR LOCALIZING AND DEFINING A TARGET POSITION IN A HUMAN BODY
WO2002040042A2 (en) 2000-11-20 2002-05-23 Oncolytics Biotech, Inc. Method for optimally delivering virus to a solid tumor mass
US6630195B1 (en) * 2000-11-21 2003-10-07 Cargill, Incorporated Process for producing oilseed protein products
US6428964B1 (en) 2001-03-15 2002-08-06 Exact Sciences Corporation Method for alteration detection
US20020193685A1 (en) * 2001-06-08 2002-12-19 Calypso Medical, Inc. Guided Radiation Therapy System
US20030036700A1 (en) 2001-07-20 2003-02-20 Weinberg Irving N. Internal/external coincident gamma camera system
US7060020B2 (en) * 2001-11-02 2006-06-13 Ideamatrix, Inc. Delivery system and method for interstitial radiation therapy
US6812842B2 (en) * 2001-12-20 2004-11-02 Calypso Medical Technologies, Inc. System for excitation of a leadless miniature marker
US6838990B2 (en) * 2001-12-20 2005-01-04 Calypso Medical Technologies, Inc. System for excitation leadless miniature marker
US6822570B2 (en) * 2001-12-20 2004-11-23 Calypso Medical Technologies, Inc. System for spatially adjustable excitation of leadless miniature marker
JP4238373B2 (en) * 2002-05-20 2009-03-18 三菱重工業株式会社 Radiation source position detection method and radiation source position detection system
US20040034297A1 (en) * 2002-08-13 2004-02-19 General Electric Company Medical device positioning system and method
ATE412446T1 (en) * 2002-09-10 2008-11-15 Cianna Medical Inc BRACHYTHERAPY DEVICE
US6847838B1 (en) * 2002-09-19 2005-01-25 Southeastern Universities Research Assn., Inc. Apparatus and method for high dose rate brachytherapy radiation treatment
US7041047B2 (en) * 2002-10-04 2006-05-09 Boston Scientific Scimed, Inc. Method and apparatus for the delivery of brachytherapy
US8027712B2 (en) * 2002-10-11 2011-09-27 Ion Beam Applications S.A. Elongated markers for soft tissue volume identification
US6889833B2 (en) * 2002-12-30 2005-05-10 Calypso Medical Technologies, Inc. Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems
US7247160B2 (en) * 2002-12-30 2007-07-24 Calypso Medical Technologies, Inc. Apparatuses and methods for percutaneously implanting objects in patients
US7289839B2 (en) * 2002-12-30 2007-10-30 Calypso Medical Technologies, Inc. Implantable marker with a leadless signal transmitter compatible for use in magnetic resonance devices
US6749555B1 (en) * 2003-02-13 2004-06-15 Proxima Therapeutics, Inc. System and method for the treatment of spinal metastases
US20040199072A1 (en) 2003-04-01 2004-10-07 Stacy Sprouse Integrated electromagnetic navigation and patient positioning device
US7570987B2 (en) * 2003-04-04 2009-08-04 Brainlab Ag Perspective registration and visualization of internal areas of the body
AU2004203173A1 (en) * 2003-07-14 2005-02-03 Sunnybrook And Women's College And Health Sciences Centre Optical image-based position tracking for magnetic resonance imaging
US20050027196A1 (en) * 2003-07-30 2005-02-03 Fitzgerald Loretta A. System for processing patient radiation treatment data
US20050085717A1 (en) * 2003-10-21 2005-04-21 Ramin Shahidi Systems and methods for intraoperative targetting
US7684849B2 (en) 2003-12-31 2010-03-23 Calypso Medical Technologies, Inc. Marker localization sensing system synchronized with radiation source
US6977504B2 (en) 2003-12-31 2005-12-20 Calypso Medical Technologies, Inc. Receiver used in marker localization sensing system using coherent detection
CA2974143C (en) * 2004-02-20 2020-11-10 University Of Florida Research Foundation, Inc. System for delivering conformal radiation therapy while simultaneously imaging soft tissue
CA2505464C (en) * 2004-04-28 2013-12-10 Sunnybrook And Women's College Health Sciences Centre Catheter tracking with phase information
EP1805506A4 (en) * 2004-08-12 2010-06-02 Navotek Medical Ltd Localization of a radioactive source within a body of a subject
WO2006043276A2 (en) * 2004-10-19 2006-04-27 Navotek Medical Ltd. Locating a catheter tip using a tracked guide
EP1922011B1 (en) * 2005-08-11 2012-05-02 Navotek Medical Ltd. Localization of a radioactive source
BRPI0616514A2 (en) * 2005-08-11 2011-06-21 Navotek Medical Ltd medical treatment system and method using position sensor based radioactivity
EP1922113A1 (en) * 2005-08-11 2008-05-21 Navotek Medical Ltd. Medical treatment system and method using radioactivity based position sensor

Also Published As

Publication number Publication date
US20090127459A1 (en) 2009-05-21
EP1922011B1 (en) 2012-05-02
US7952079B2 (en) 2011-05-31
WO2007017846A2 (en) 2007-02-15
US8198600B2 (en) 2012-06-12
WO2007017846A3 (en) 2007-09-07
US20110198510A1 (en) 2011-08-18
EP1922011A2 (en) 2008-05-21

Similar Documents

Publication Publication Date Title
WO2007017846A8 (en) Localization of a radioactive source
WO2006016368A3 (en) Localization of a radioactive source within a body of a subject
NZ603613A (en) Point-of-care fluidic systems and uses thereof
HK1078651A1 (en) Distance measurement sensor
WO2006055770A3 (en) Robot cell calibration
EP2239567A3 (en) Calibration techniques for a continuous analyte sensor
EP1746334A3 (en) Laser protection wall for shielding a laser radiation area
FR2844349B1 (en) CAPACITIVE SENSOR PROXIMITY DETECTOR
WO2009071858A3 (en) Ionising radiation detector
WO2007027797A3 (en) Methods, systems, and computer program products for measuring the density of material
WO2005081200A3 (en) Detection device for a motor vehicle
WO2005033283A3 (en) Methods for enhancing the analysis of particle detection
WO2016038416A3 (en) Proximity sensor systems and methods of operating same
WO2007127053A3 (en) Non-intrusive pressure gage
WO2008141919A3 (en) Apparatus for the detection of light in a scanning microscope
WO2006044960A3 (en) Position detection apparatus and method for linear and rotary sensing applications
WO2006115551A8 (en) Variable geometry reference array
WO2007064542A3 (en) Systems and methods for tdoa/fdoa location
ITRM20050353A1 (en) DETECTOR LOW POWER HIGHER DETECTION AMPLIFIER.
WO2004010083A3 (en) Sensors isolated by an intrinsically safe barrier
WO2007062084A3 (en) Measuring device for conveyor chain
WO2006111472A3 (en) Sensor for eliminating undesired components and measurement method using said sensor
WO2007069170A3 (en) Method and apparatus for position optimization of a field generator
WO2004089208A8 (en) Microwave based monitoring system and method
SE0502659L (en) Magnetic detector arrangement

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 11990315

Country of ref document: US

Ref document number: 189442

Country of ref document: IL

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2006795628

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2006795628

Country of ref document: EP