WO2007016279A2 - Magnetic core for medical procedures - Google Patents
Magnetic core for medical procedures Download PDFInfo
- Publication number
- WO2007016279A2 WO2007016279A2 PCT/US2006/029266 US2006029266W WO2007016279A2 WO 2007016279 A2 WO2007016279 A2 WO 2007016279A2 US 2006029266 W US2006029266 W US 2006029266W WO 2007016279 A2 WO2007016279 A2 WO 2007016279A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- core
- magnetic
- patient
- ferromagnetic
- conductor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/004—Magnetotherapy specially adapted for a specific therapy
- A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
Definitions
- Neurons and muscle cells are a form of biological circuitry that carry electrical signals and respond to electromagnetic stimuli.
- an ordinary conductive wire loop is passed through a magnetic field or is in the presence of a changing magnetic field, an electric current is induced in the wire.
- a nerve cell or neuron can be stimulated in a number of ways, including transcutaneously via transcranial magnetic stimulation (TMS), for example.
- TMS uses a rapidly changing magnetic field to induce a current on a nerve cell, without having to cut or penetrate the skin.
- the nerve is said to "fire” when a membrane potential within the nerve rises with respect to iit ⁇ bni ⁇ ridgaiWKSMbiMtTOVWffiil 1 approximately -90 millivolts, depending on the type of nerve and local pH of the surrounding tissue.
- magnetic stimulation is very effective in rehabilitating injured or paralyzed muscle groups. Apart from stimulation of large muscle groups such as the thigh or the abdomen, experimentation has been performed in cardiac stimulation as well. In this context, magnetic stimulation of the heart may prove to be superior to CPR or electrical stimulation, because both of those methods undesirably apply gross stimulation to the entire heart all at once.
- Magnetic stimulation may be used to block the transmission of pain via nerves in the back, e.g., those responsible for lower back pain.
- Magnetic stimulation also has proven effective in stimulating regions of the brain, which is composed predominantly of neurological tissue.
- One area of particular interest is the treatment of depression. It is believed that more than 28 million people in the United States alone suffer from some type of neuropsychiatric disorder. These include conditions such as depression, schizophrenia, mania, obsessive-compulsive disorder, panic disorders, and others. Depression is the "common cold" of psychiatric disorders, believed to affect 19 million people in the United States and possibly 340 million people worldwide.
- the ferromagnetic core alternatives typically are fabricated by laminating layers of silicon steel or similar ferromagnetic metal together to form the core structure.
- the layers may be constructed by stacking cut-out shapes or by winding a ribbon of material onto a mandrel followed by further machining and processing to attain the desired core geometry.
- the ferromagnetic cores While solutions fabricated using these ferromagnetic cores offered a marked improvement over their coil-only counterparts, the ferromagnetic cores also suffer from certain comP ⁇ Mties ⁇ fe ⁇ I' ⁇ iWfe ⁇ tilcWl-afflimitations in their geometry. Specifically, the stacked layer construction method does not provide optimal alignment of the metal crystal structure with the magnetic flux lines and also requires a controlled lamination process to guarantee minimal eddy current losses.
- the wound ribbon construction method typically results in a core with arc- shaped or C-shaped structure having a certain radius and span. The dimensions and geometry of these ferromagnetic cores are selected to ensure desired depth of penetration, magnetic field shape and appropriate magnetic field magnitude at certain locations within the patient's anatomy.
- the ferromagnetic core's construction method involves a complex and meticulous construction process that increased both the complexity and cost of the core. For example, because ferromagnetic material is electrically conductive, eddy currents are established in the material when it is exposed to a rapidly varying magnetic field. These eddy currents not only heat the core material through resistive heating, but they also produce an opposing magnetic field that diminishes the primary magnetic field. To prevent these losses the eddy current pathways are broken by fabricating the core from very thin layers or sheets of ferromagnetic material that are electrically isolated from each other.
- the sheets typically are individually varnished or otherwise coated to provide insulation between the sheets, thus preventing current from circulating between sheets and resulting in reduced eddy current losses. Also, the sheets are oriented parallel to the magnetic field to assure low reluctance.
- the wound core fabrication process begins by winding a long thin ribbon of saturable ferromagnetic material, such as vanadium permendur or silicon steel, on a mandrel to create the desired radius, thickness and depth of the core. Each side of the ribbon typically is coated with a thin insulative coating to electrically isolate it. Once the ribbon has been wound on the mandrel to the desired dimensions, it is removed from the mandrel and dipped in epoxy to fix its position. Once the epoxy has cured, a sector of the toroidal core is cut with a band saw and removed, thus forming the desired arc-shape.
- saturable ferromagnetic material such as vanadium permendur or silicon steel
- each cut is finely ground so that it is smooth, and then a deep acid etch is performed.
- the deep etch is performed by dipping each of the cut ends in an acid bath. This removes any ferromagnetic material that may be shorting the laminations.
- the faces are coated to prevent oxidation and to maintain the shape and structural integrity of the core.
- the manufacturing process of cutting, coating, aligning, attaching and laminating the layers makes for a complex and costly manufacturing process. Also, these considerations make it difficult to change or customize the shape of the core structure.
- Winding a coil of insulated wire around the ferromagnetic core to deliver the current needed to create the magnetic field also is a complex and detailed process.
- a typical inductance for a core of this type is about 15-20 microHenries.
- Each pass of the winding around the core must be made at precise intervals on the core structure.
- each core has only one winding, although typically the core may be wound multiple times.
- the inventive technique include a system, method and device for treating a patient.
- the inventive system includes a magnetic field generating device created using a powdered ferromagnetic.
- the system further includes a circuit in electrical communication with the magnetic core, and a power source in electrical communication with the circuit.
- the ferromagnetic powder core may be manufactured by at least one of the following: machining, pressing, molding, gluing, and extruding.
- the ferromagnetic powder core may have a distributed gap structure, where the gap structure operates to focus the magnetic field between pole faces of the magnetic device.
- the ferromagnetic powder core may have a shaded pole face, wh p ⁇ & m - M cut into the face of the pole with a shorted turn inserted into the channel.
- the ferromagnetic powder core may comprise a ferromagnetic electrically conductive material such as iron or a non-ferromagnetic material such as copper, brass and/or aluminum, for example.
- the system may include a wire or conductor that is wound around a bobbin structure that acts to insulate the wire from the core structure.
- the inventive method of treating a patient includes creating a magnetic field using a magnetic device having a non-linear ferromagnetic powder core and applying the magnetic field to the patient to treat the patient as a function of the magnetic field.
- the inventive method further may use a ferromagnetic powder core that has a distributed gap structure that focuses the magnetic field between pole faces of the magnetic device via the distributed gap core structure.
- the ferromagnetic powder core may include a ferromagnetic electrically conductive material such as iron and/or a non-ferromagnetic material such as copper, brass and aluminum.
- Figures 1 through 13 illustrate example core shapes and configurations, in accordance with the invention
- Figure 14 is a flow diagram of a method for treating a patient
- Figure 15 is a block diagram of a system for treating a patient.
- Figure 16 is a flow diagram of a method for manufacturing a magnetic core for treating a patient.
- a distributed gap core structure is contemplated, for example an air gap core structure.
- the air gap core refers to the internal structure of a magnetic core, while the "air core” discussed in the Background of the Invention section refers to a winding without any magnetic core.
- One type of matrix of insulating material It should be appreciated that the invention is not limited to an ferromagnetic powder core, but various embodiments may include any gap core structure.
- the gap core structure may be any structure where one or more conductive particles are insulated (or
- the use of distributed gap core structures like powdered ferromagnetic core materials reduces the complex manufacturing and corresponding cost burden inherent in the laminated structures.
- the core is less conductive, and as a result eddy current losses are minimal. More specifically, the non-conductive gaps may prohibit the flow of current from one ferromagnetic particle to the next, and thus reduce overall current flow in the core. Because eddy currents result from the conductive flow of current in magnetic materials like the core, reducing the conductive flow serves to reduce the eddy currents. As a result of the reduced eddy currents, the distributed gap core structure produces even less heat than its counterpart ferromagnetic core structures.
- higher power and current levels may be used to drive coils fabricated with a distributed gap core without concern for heating that may be excessive for a patient undergoing treatment.
- these higher power levels may be achieved without the need for sophisticated cooling systems, typical of the "air" core solutions.
- these higher current drive levels may drive the distributed gap cores closer to their saturation level to obtain greater magnetic field strength, without concern for consequent undesirable heating.
- heating due to resistive losses in the windings may be greater than heat generated within the distributed gap core material. In other words, the heating characteristics of the windings may provide the only real heating concerns for patient use.
- the core may additionally be enclosed in a structure that further enhances its thermal performance. For example, by potting the core into a shell heat may be directed to a desirable surface for radiation to the surrounding air. Such a surface may, for example, be located away from surfaces that touch a patient or the operator.
- Air spaces and thermal insulation also may be added between the windings or other heat generating materials to insulate them from surfaces that may come in contact with a patient, for example. Typically these surfaces must be kept at or below 41.5 degrees Celsius in order to comply with medical device standards, well known to those skilled in the art.
- the insulative material may be any material that offers a different level of permeability and inductance as compared to the ferromagnetic particles.
- the magnetic flux path is increased, thus reducing the permeability and the inductance of the core material.
- It may be desirable to have a core with a permeability, of greater than 1.
- the distributed gap reduces eddy currents, there are fewer flux distortions. This relatively greater isotropic structure provides for a more uniformly distributed flux and facilitates more complex and sophisticated core structures.
- the ferromagnetic powder used to make the core may be made of particles that are less than 0.05 inch in diameter.
- the particles may be of any size in the contemplated embodiments, it should be appreciated that the specific particle dimension is related to the frequency at which the core is to operate. For example, if the core is to ⁇ 'puisfetfaM ⁇ dll lS t ay e es ra e to use part c es w th a smaller dimension.
- the ferromagnetic particles may vary in size and may not be spherical but rather irregular in shape. In any event, it should be appreciated that specific particle size may be selected to reduce losses resulting from eddy currents and hysteresis losses within individual particles.
- individual ferromagnetic particles may be formulated from iron, iron alloys and amalgams of other conductive or partially conductive materials.
- the material composition of the particles may include non-ferrous metals such as copper, brass, aluminum and alloying elements such as carbon, silicon, nickel and chromium formulated to create the desired crystal structure and desired magnetic characteristics. Saturation, permeability and B-H curve characteristics vary depend on this selected formulation.
- the ferromagnetic particles may be coated with a non-conductive resin to, among other things, prevent oxidation while being stored before the coated particles are formed into the desired structure in the core manufacturing process.
- the contemplated embodiments include a method for manufacturing a magnetic core device, for example a powdered ferromagnetic core device.
- the method includes selecting certain powdered ferromagnetic materials. The materials are then mixed and compressed to form the core.
- the powder may be pressed into a mold having the final form of the core.
- blocks of compressed material can be manufactured and subsequently machined to the desired geometry.
- separate molded or machined component pieces may be mechanically assembled into the final core geometry using cement, heating or bonding by other mechanical means.
- the ferromagnetic powder core may be produced by any of several processes. For example, stream of molten iron may be atomized by a high pressure water jet.
- the ferromagnetic particles may be coated with any appropriate substance.
- the ferromagnetic particles may be coated with an insulative substance, like alkali metal silicate, for example.
- the insulative substance provides insulation between each of the partltflS® ift th ⁇ ⁇ M ? i i i ! d''tH
- an aqueous alkali metal silicate solution is used containing up to 39% by weight solids of K 2 O and SiO 2 , and up to 54% by weight solids of Na 2 O and SiO 2 .
- a wetting agent or surfactant, like alkyl phenoxyl polyethoxy ethanol for example, may be added to facilitate uniform coating of the particles.
- the appropriate substances are mixed and may be surface-dried at the same time.
- a thin coating of an adherent resin may be applied to the ferromagnetic particles.
- Such resins may include polyimides, fluorocarbons and acrylics. The resin permits the particles to remain flexible and thus capable of withstanding high temperatures without decomposing into conducting residues.
- the powder is compressed.
- the compression may be approximately in the range of 25 to 100 tons per square inch.
- a form may be used to create the desired shape.
- the pressed components may be annealed, for example, at 500 to 600 degrees Celsius to relieve the stresses and reduce the hysteresis losses.
- the particles may be insulated from one another, for example, with between 1% to 3% spacing between particles.
- the density remains 1% or 2% below the true density of solid iron, because of residual crevices or interstices which remain empty or are filled with lower density resin.
- the ferromagnetic powder may be compressed to about 90% of theoretical density or better in order to have a distributed insulation- containing air gap less than 3% in each of the three orthogonal directions, one of which is that of the flux path.
- the magnetic core may be a composition that allows the core to saturate at 0.5 Tesla or greater, for example.
- the individual ferromagnetic particles in the powder may be mixed with a binding material, for example phenolic or epoxy.
- the ferromagnetic powder may then be pressed into its final shape.
- a baking or heating process mayi pl ⁇ i ⁇ Wr ⁇ 'eWm iSd lihaterial.
- the ferromagnetic particles may be separated by air or insulative binding material which effectively results in a distributed gap. As a result, the gap is distributed throughout the core.
- novel device and techniques may be used for many purposes including the treatment of patients with medical conditions. This applicability will be discussed in the context of TMS in order to provide greater understanding. However, it should be appreciated that techniques have applicability beyond TMS also are contemplated by the invention.
- a method of treating a patient by creating a magnetic field using a magnetic device having a non-linear core is contemplated.
- the core may assume a number of different and various shapes and sizes. The shapes and sizes may vary with the particular area of the patient's anatomy that needs treatment, as well as the external area of the patient on which the magnet may be placed.
- the core may have a U-shaped structure that facilitates placing the core in close proximity to a patient's head for the purpose of treating the brain with pulsed magnetic fields for the treatment of depression. This may be accomplished, for example, by stimulating tissue (e.g., brain tissue), nerves and/or muscle, for example, from an area relatively proximate to the cutaneous surface and the area of treatment.
- stimulating tissue e.g., brain tissue
- nerves and/or muscle for example, from an area relatively proximate to the cutaneous surface and the area of treatment.
- the core used to treat the patient may be a gap distributed core and more specifically an ferromagnetic powder core.
- the embodiments are not limited to any compositions, but contemplate any material composition that effectively creates a distributed gap core structure.
- the embodiments contemplate any type of core structures, including ferromagnetic, where the shape of the core structure has a non-arc shaped structure.
- the embodiments contemplate the use of a non-sintered core material.
- other embodiments contemplate a non-linear shaped ferromagnetic powder core.
- the magnetic field passing through the core may be applied to the patient for the purpose of treating or diagnosing the patient.
- the embodiments are not limited to a specific but instead contemplate any field strength, focus and duration necessary to treat or diagnose the desired patient.
- a novel system may include a magnetic field generating device created using a powdered ferromagnetic core, a circuit in electrical communication with the magnetic core, and being drive by a power source in electrical communication with the circuit.
- a power source may be provided in order for the core to generate the requisite magnetic field.
- the power source may be in electrical communication with the windings wrapped around a portion of the core.
- the power source may be created to provide a substantially constant power or substantially constant current source.
- the power source may provide a substantially constant power or substantially constant current source to a capacitor, which then discharges to the core to create the magnetic field.
- the power source may operate on an alternating current input voltage in the range of 85 volts to 264 volts. In this way, the inventive device may operate using power typically available in residential and commercial settings.
- the embodiments contemplate a method for treating depression.
- a patient is selected who suffering from a depressive disorder.
- the patient's brain is then magnetically stimulated using a transcranial magnetic stimulator with a magnetic core.
- the core may be a ferromagnetic core having a U-shaped structure and/or a distributed gap core structure having any core shape and structure.
- ferromagnetic powder core makes more feasible many possible core geometries.
- the distributed gap core ⁇ e.g., ferromagnetic powder core
- the core's geometry allows the core's geometry to have an array of possibilities.
- the precise shape and size of the core's geometry may be made to vary depending upon various factors. For example, although not an exclusive list of considerations, the following may be considered in deciding upon the size and geometry of the core: the use of the core, the available mounting area and volume, the allowable radiation, the limitations on windings, the operating Consequently, a core's geometrical shape can take any form, including a cylinder, bobbin, toroid, a non-toroid or several other possible shapes.
- the ferromagnetic powder manufacturing process facilitates construction of the core as multiple components or pieces.
- Multi-piece ferromagnetic powder cores each piece made of similar or different magnetic material, may be used for extremely complex shapes or larger core constructions. These individual pieces, of different or similar permeabilities, may be brought together by gluing and/or any. other attachment techniques well known to those skilled in the art. This is facilitated, in part, due to the ease of manufacturing and core shaping provided by the powder core process.
- the powder core manufacturing process also facilitates the use of other materials to shape the magnetic field provided by the core structure. For example, it may be desirable to deflect or redirect a certain portion of the created magnetic field away from certain parts of the anatomy. For example, for brain stimulation, it may be desirable to protect the trigeminal nerve from being stimulated and causing discomfort to the patient. This may be accomplished using any number of techniques.
- One example technique locates a conductor on a treatment area relative to the protected area.
- the conductor may act to reduce stimulation of a cutaneous-proximate area on the patient. This may be accomplished by modifying an electric or magnetic field created by the transcutaneous stimulation. Also, it may be accomplished via modification of the electric field through modification of the magnetic flux created by the transcutaneous stimulation.
- Figures 1 through 13 provide various examples of core shapes and configurations that are facilitated by the contemplated embodiments. It should be appreciated, however, that Figures 1 through 13 are not provided in order to detail every possible shape and configuration contemplated by the invention. Instead, the figures merely provide certain examples to aid in an understanding of just a few of the contemplated embodiments. ⁇ [0 ⁇ 53 ⁇ IJ 'Wr liy iiy Wloted that the magnetic cores shown in Figures 1 through 13 essentially comprise three sections. Although the cores may not have to be separately constructed in three of such sections, describing their shape as such facilitates further discussion of the shape, and thus is not meant to be limiting in any way.
- a core 100 includes a first section 101, a second section 102 and a third section 103.
- second section 102 serves as a bridge connecting first section 101 and third section 103, which serve as the posts or poles for the U- shape.
- First section 101 is joined with second section 102 at a right angle.
- third section 103 is joined with second section 102 at a right angle. It should be appreciated that these sections may be fabricated as one complete pressed part, or they could be individually pressed and later assembled to form the U-shape.
- FIG. 1 various other shapes and configurations that may be modifications or minor alterations are depicted in Figure 1.
- either ends of the first, second and/or third sections may be angled or chamfered. Such angles or chamfering may be accomplished using any such value, for example using an angle of 45 degrees.
- Such modifications to the shape of the pole face are used by those skilled in the art to redirect and optimize the spatial distribution of the magnetic field for the intended application.
- the angled sections may be arc-shaped as shown in Figure 3.
- the angles may be made to both the cornered ends of the core as shown in Figure 2, or on just one of the cornered ends of the core as shown in Figure 13. Similarly, the angles may be made at the opposite ends with respect to the cornered ends, as shown in Figure 5.
- the angles depicted in Figure 5 may be arc-shaped or smoothed, as shown in Figures 4 and 6.
- the first and third sections may be L-shaped as shown in Figure 7 with a linear second section, or as shown in Figure 8 with an arc-shaped second section. .
- W ' nifn Kf tM ⁇ the magnetic core may be arc-shaped core having a wire wound around any portion of its axis.
- the core may be a linear-shaped structure having perpendicular or chamfered ends with respect to its main axis.
- a wire may be wound around any portion of its axis.
- the wound wire may be a single strand and or multiple strands in parallel electrically.
- the wire may include a metal sheet of conductive material with or without insulation, and or an extruded magnet wire with or without insulation.
- the core may have more than 2 poles with windings around one or more of the poles.
- the construction, size and shape of the core may be made to be dependent upon how the windings will be installed on the core component.
- certain embodiments contemplate windings that are wound directly around and/or on the core.
- other embodiments may include windings that are wound on a sleeve or bobbin that is slipped over a portion of the core, or are wound on a mandrel, potted and removed for subsequent assembly onto the core.
- certain embodiments may include a combination of the these approaches.
- a channel may be cut into the face of the pole in order to allow windings or wire to be installed. For example, a shorted turn may be inserted into the channel and connected together outside of the channel.
- the wire used for the windings may be insulated to prevent closely wound, adjacent turns from shorting out.
- the wire may be of such a gauge as to prevent the core from cutting through the insulation, for example with sharp surfaces or edges. Therefore, to accommodate such directly wound cores, the core may have a smooth winding surface, or in some cases may provide a corner radius to accommodate the turns.
- the bobbin may be a structure that includes a single bobbin or multiple bobbins.
- the bobbin may provide insulation properties with respect to the rest of the core, as well as providing operation and safety capabilities.
- the wire may be wound around the pole faces of the core. Where wire is wound around two or more poles, the number of turns of the winding may be e i' ⁇ tf bht$M ⁇ PbMP$ ⁇ [ ⁇ $ "AlStII- I tM wire may be wound around a central point of the core, instead of or in addition to being wound around the pole faces of the core. Where wound around both, the number of turns of the winding around the pole faces may be a fraction of the number of turns around the central point of the core.
- a bobbin may be more readily used to accurately prefabricate and position the winding on the core.
- Figures IB, 2B and 3B illustrate how one or more wires may be wound around at least a portion of the magnetic core.
- the windings may be wound around the first and third sections of the core.
- Such a winding may be a single winding wound around the first and third sections, or two or more individual windings each wound around the first and third sections.
- the winding may be wound around the second section of the core.
- the core winding may be a single winding or multiple windings.
- Figure 14 is a flow diagram of a method for treating a patient.
- a magnetic field is created using a distributed gap core magnetic device.
- the magnetic device is placed proximate to a cutaneous area on the patient, for example, in proximity to the patient's head.
- a portion of the patient's anatomy that is desired to be treated e.g., brain
- the magnetic field is applied to the patient.
- the patient is treated, for example for depression, incontinence, and weight control, with the magnetic field.
- Other types of conditions also may be treated using these techniques. These may include, but are not limited to, treating the peripheral nervous system, rehabilitating the patient's muscle.
- the described techniques further may be used to directly diagnose a patient's condition. Also, the techniques may be used to diagnose a resp ⁇ to r smm ⁇ c i f r to quanti y ef ect veness of such therapies.
- pharmaceuticals may have effects (i.e., direct or secondary) on the performance of the central nervous system. These effects may be observed by providing stimulation (e.g., TMS) and observing evoked potentials, motor response, conduction velocities or other responses, just to name a few of the many contemplated observed effects. Changes in response may be used to quantify performance or to determine optimal dosing, for example.
- pathologies may be diagnosed using the described techniques an investigative tool to observe neurological response.
- pathologies include, but are not limited to, degenerative diseases, extent of traumatic injury, progression of diseases, systemic deficiencies, and congenital anomalies (e.g., tinnitus).
- a partial list of such conditions is provided here for the purposes of further understanding.
- the scope of the described embodiments are not limited to this list.
- These include assessment or measuring effect of pharmaceuticals, including anti-convulsives, Alzheimer's medications, anti-psychotics, pain medications, anti-anxiety, hypnotics (sedatives), analgesics (central), ADHD medications and, anesthetics.
- Other disorders may also be treated with the described techniques including treating a patient such as a human suffering from major depressive disorder, epilepsy, schizophrenia, Parkinson's disease, Tourette's syndrome, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), Alzheimer's disease, attention deficit/hyperactivity disorder, obesity, bipolar disorder/mania, anxiety disorders (panic disorder with and without agoraphobia, social phobia also known as social anxiety disorder, acute stress disorder, generalized anxiety disorder), post-traumatic stress disorder (one of the anxiety disorders in DSM), obsessive compulsive diso *i n mM ⁇ i t mmmh DSM , pain migraine, trigeminal neuralgia) (also: chronic pain disorders, including neuropathic pain, e.g., pain due to diabetic neuropathy, postherpetic neuralgia, and idiopathic pain disorders, e.g., fibromyalgia, regional myofascial pain syndromes), rehabilitation following stroke (neuropathic pain,
- the method further may include determining so-called "motor threshold" of the patient. More specifically, the magnetic device may be moved over a particular area until some indication of positioning is provided. For example, in the context of magnetic stimulation of the brain, the magnetic device may be moved over the patient's head until the patient's thumb moves or twitches indicating a motor threshold point. This motor threshold determination may be at a similar or different frequency, for example, using a stimulation frequency rate of 1 Hz.
- the magnetic device may be moved to a desired treatment location.
- the magnetic device may located approximately 5 centimeters anteriorly from motor threshold point.
- the stimulator output may be set to approximately 110% of relaxed motor threshold with perhaps a repetition rate of approximately 10 Hz.
- Figure 15 is a block diagram of a system for treating a patient.
- a system 1500 for treating a patient includes a magnetic field generating device 1501. distributed gap core structure.
- a circuit 1502 is in electrical communication with the magnetic field generating device.
- the circuit may be act as a switch to pulse the magnetic field generating device in such a way to treat the desired condition.
- the magnetic field may be applied to the patient in cycles intermittently.
- the exact stimulation frequency or frequency in which the magnet is pulsed may be varied depending upon the particular application (e.g., size of magnet and area of stimulation). For example, in just some embodiments, it may be desirable to stimulate for a five second period, followed by rest for a five second period and then repeat stimulation continuously for another five seconds. While they are being stimulated, it is desirable to have the muscle groups continuously excited. This requirement dictates the necessity of continuing to pulse the cores at a repetition rate of 15 Hz.
- a power source 1503 may be in electrical communication with the circuit.
- the power source may provide direct current (dc) or alternating current (ac) power.
- the power levels may be consistent with those available in residential and commercial settings.
- Figure 16 is a flow diagram of a method for manufacturing a magnetic core for treating a patient.
- ferromagnetic particles are selected with an insulated coating.
- the ferromagnetic particles are mixed and in 1602, the ferromagnetic particles are formed into a core structure.
- a conductor e.g., wire
- a power source is connected to the core structure.
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK06788702.6T DK1912699T3 (en) | 2005-07-27 | 2006-07-26 | Magnetic core for medical procedures |
AU2006275713A AU2006275713B2 (en) | 2005-07-27 | 2006-07-26 | Magnetic core for medical procedures |
JP2008524159A JP2009502350A (en) | 2005-07-27 | 2006-07-26 | Magnetic core for medical procedures |
CA2617033A CA2617033C (en) | 2005-07-27 | 2006-07-26 | Magnetic core for medical procedures |
ES06788702.6T ES2665912T3 (en) | 2005-07-27 | 2006-07-26 | Magnetic core for medical procedures |
EP17205912.3A EP3332837B1 (en) | 2005-07-27 | 2006-07-26 | Magnetic core for medical procedures |
EP06788702.6A EP1912699B1 (en) | 2005-07-27 | 2006-07-26 | Magnetic core for medical procedures |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/191,106 US7824324B2 (en) | 2005-07-27 | 2005-07-27 | Magnetic core for medical procedures |
US11/191,106 | 2005-07-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007016279A2 true WO2007016279A2 (en) | 2007-02-08 |
WO2007016279A3 WO2007016279A3 (en) | 2007-09-27 |
Family
ID=37695263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/029266 WO2007016279A2 (en) | 2005-07-27 | 2006-07-26 | Magnetic core for medical procedures |
Country Status (8)
Country | Link |
---|---|
US (8) | US7824324B2 (en) |
EP (2) | EP3332837B1 (en) |
JP (5) | JP2009502350A (en) |
AU (1) | AU2006275713B2 (en) |
CA (1) | CA2617033C (en) |
DK (2) | DK3332837T3 (en) |
ES (2) | ES2665912T3 (en) |
WO (1) | WO2007016279A2 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008200205A (en) * | 2007-02-19 | 2008-09-04 | Kanazawa Univ | Magnetic field generator for bone disorder treatment and evaluation and development system of bone disorder treatment using the same |
DE112008004049T5 (en) | 2008-10-31 | 2012-06-06 | Nexstim Oy, | Magnetic stimulation coils with electrically conductive structures |
IT201600092729A1 (en) * | 2016-09-14 | 2018-03-14 | Policlinico San Donato S P A Istituto Di Ricovero E Cura A Carattere Scient | Method and system for modulating brain electrical activity |
WO2018051263A1 (en) * | 2016-09-14 | 2018-03-22 | Policlinico San Donato S.P.A. - Istituto Di Ricovero E Cura A Carattere Scientifico | Method and system for modulating the brain electrical activity |
US10232187B2 (en) | 2014-02-14 | 2019-03-19 | Osaka University | Coil device and transcranial magnetic stimulation system |
Families Citing this family (90)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8052591B2 (en) | 2006-05-05 | 2011-11-08 | The Board Of Trustees Of The Leland Stanford Junior University | Trajectory-based deep-brain stereotactic transcranial magnetic stimulation |
US7976451B2 (en) | 2005-06-16 | 2011-07-12 | The United States Of America As Represented By The Department Of Health And Human Services | Transcranial magnetic stimulation system and methods |
US7824324B2 (en) * | 2005-07-27 | 2010-11-02 | Neuronetics, Inc. | Magnetic core for medical procedures |
US9339641B2 (en) | 2006-01-17 | 2016-05-17 | Emkinetics, Inc. | Method and apparatus for transdermal stimulation over the palmar and plantar surfaces |
US9610459B2 (en) * | 2009-07-24 | 2017-04-04 | Emkinetics, Inc. | Cooling systems and methods for conductive coils |
US20100168501A1 (en) * | 2006-10-02 | 2010-07-01 | Daniel Rogers Burnett | Method and apparatus for magnetic induction therapy |
US9352167B2 (en) | 2006-05-05 | 2016-05-31 | Rio Grande Neurosciences, Inc. | Enhanced spatial summation for deep-brain transcranial magnetic stimulation |
US8267850B2 (en) | 2007-11-27 | 2012-09-18 | Cervel Neurotech, Inc. | Transcranial magnet stimulation of deep brain targets |
US10786669B2 (en) | 2006-10-02 | 2020-09-29 | Emkinetics, Inc. | Method and apparatus for transdermal stimulation over the palmar and plantar surfaces |
WO2008042902A2 (en) * | 2006-10-02 | 2008-04-10 | Emkinetics, Inc. | Method and apparatus for magnetic induction therapy |
US9005102B2 (en) | 2006-10-02 | 2015-04-14 | Emkinetics, Inc. | Method and apparatus for electrical stimulation therapy |
US11224742B2 (en) | 2006-10-02 | 2022-01-18 | Emkinetics, Inc. | Methods and devices for performing electrical stimulation to treat various conditions |
WO2009020938A1 (en) * | 2007-08-05 | 2009-02-12 | Neostim, Inc. | Monophasic multi-coil arrays for trancranial magnetic stimulation |
WO2009055634A1 (en) * | 2007-10-24 | 2009-04-30 | Neostim Inc. | Intra-session control of transcranial magnetic stimulation |
US8956273B2 (en) * | 2007-08-20 | 2015-02-17 | Cervel Neurotech, Inc. | Firing patterns for deep brain transcranial magnetic stimulation |
US8956274B2 (en) * | 2007-08-05 | 2015-02-17 | Cervel Neurotech, Inc. | Transcranial magnetic stimulation field shaping |
US20100185042A1 (en) * | 2007-08-05 | 2010-07-22 | Schneider M Bret | Control and coordination of transcranial magnetic stimulation electromagnets for modulation of deep brain targets |
US20100256439A1 (en) * | 2007-08-13 | 2010-10-07 | Schneider M Bret | Gantry and switches for position-based triggering of tms pulses in moving coils |
US20100331602A1 (en) * | 2007-09-09 | 2010-12-30 | Mishelevich David J | Focused magnetic fields |
US7994780B2 (en) * | 2007-09-14 | 2011-08-09 | General Electric Company | System and method for inspection of parts with an eddy current probe |
WO2009049068A1 (en) * | 2007-10-09 | 2009-04-16 | Neostim, Inc. | Display of modeled magnetic fields |
US20100286468A1 (en) * | 2007-10-26 | 2010-11-11 | David J Mishelevich | Transcranial magnetic stimulation with protection of magnet-adjacent structures |
US20090108969A1 (en) * | 2007-10-31 | 2009-04-30 | Los Alamos National Security | Apparatus and method for transcranial and nerve magnetic stimulation |
AU2008329676B2 (en) | 2007-11-26 | 2015-03-05 | Attractive Surgical, Llc | Magnaretractor system and method |
JPWO2009119236A1 (en) * | 2008-03-26 | 2011-07-21 | テルモ株式会社 | Treatment device |
US8795148B2 (en) * | 2009-10-26 | 2014-08-05 | Cervel Neurotech, Inc. | Sub-motor-threshold stimulation of deep brain targets using transcranial magnetic stimulation |
US8723628B2 (en) | 2009-01-07 | 2014-05-13 | Cervel Neurotech, Inc. | Shaped coils for transcranial magnetic stimulation |
US8657732B2 (en) * | 2009-01-30 | 2014-02-25 | Sbf Healthcare Pvt. Ltd. | Sequentially programmed magnetic field therapeutic system (SPMF) |
CL2009000279A1 (en) | 2009-02-06 | 2009-08-14 | Biotech Innovations Ltda | Remote guidance and traction system for mini-invasive surgery, comprising: at least one surgical and removable endopinza with hooking means and a portion of ferro-magnaetic material, a cylindrical introduction guide, a detachment mechanism, and at least a means of remote traction with magnet. |
JP2013508119A (en) | 2009-10-26 | 2013-03-07 | エムキネティクス, インコーポレイテッド | Method and apparatus for electromagnetic stimulation of nerves, muscles and body tissues |
NO20093315A1 (en) * | 2009-11-11 | 2011-05-12 | Laerdal Medical As | Method and system for painting parameters of the chest, especially in cardiac lung rescue |
US8588884B2 (en) | 2010-05-28 | 2013-11-19 | Emkinetics, Inc. | Microneedle electrode |
US9492679B2 (en) | 2010-07-16 | 2016-11-15 | Rio Grande Neurosciences, Inc. | Transcranial magnetic stimulation for altering susceptibility of tissue to pharmaceuticals and radiation |
US8739799B2 (en) * | 2011-07-05 | 2014-06-03 | Jack Y Dea | Non-contact electronic tool for dream enhancement |
DE102011082045A1 (en) * | 2011-09-02 | 2013-03-07 | Schmidhauser Ag | Throttle and related manufacturing process |
DE102012013534B3 (en) | 2012-07-05 | 2013-09-19 | Tobias Sokolowski | Apparatus for repetitive nerve stimulation for the degradation of adipose tissue by means of inductive magnetic fields |
US9682248B2 (en) | 2012-09-20 | 2017-06-20 | University Of Rochester | Deep brain magnetic stimulator |
US9248308B2 (en) | 2013-02-21 | 2016-02-02 | Brainsway, Ltd. | Circular coils for deep transcranial magnetic stimulation |
US9254394B2 (en) | 2013-02-21 | 2016-02-09 | Brainsway, Ltd. | Central base coils for deep transcranial magnetic stimulation |
US9533168B2 (en) | 2013-02-21 | 2017-01-03 | Brainsway, Ltd. | Unilateral coils for deep transcranial magnetic stimulation |
US8764769B1 (en) | 2013-03-12 | 2014-07-01 | Levita Magnetics International Corp. | Grasper with magnetically-controlled positioning |
US10010370B2 (en) | 2013-03-14 | 2018-07-03 | Levita Magnetics International Corp. | Magnetic control assemblies and systems therefor |
US9072891B1 (en) | 2013-06-04 | 2015-07-07 | Dantam K. Rao | Wearable medical device |
DE102013114563A1 (en) * | 2013-12-19 | 2015-06-25 | Valeo Schalter Und Sensoren Gmbh | A method for performing a parking operation of a motor vehicle in a transverse parking space, parking assistance system and motor vehicle |
US9849301B2 (en) * | 2014-01-15 | 2017-12-26 | Neuronetics, Inc. | Magnetic stimulation coils and ferromagnetic components for reduced surface stimulation and improved treatment depth |
EP3096673A4 (en) | 2014-01-21 | 2017-10-25 | Levita Magnetics International Corp. | Laparoscopic graspers and systems therefor |
US9925388B2 (en) * | 2014-03-26 | 2018-03-27 | Northeastern University | Device and method for deep transcranial magnetic stimulation |
WO2015153868A1 (en) | 2014-04-02 | 2015-10-08 | University Of Maryland, Baltimore | Methods and systems for controlling magnetic fields and magnetic field induced current |
US10658758B2 (en) | 2014-04-17 | 2020-05-19 | The Boeing Company | Modular antenna assembly |
CA2985822A1 (en) * | 2014-06-02 | 2015-12-10 | Monash University | Magnetic circuit for producing a concentrated magnetic field |
US9789330B1 (en) | 2014-10-28 | 2017-10-17 | Knowledge Technologies, LLC | Apparatus for transcranial magnetic stimulation |
EP3841967B1 (en) * | 2015-01-06 | 2023-10-25 | David Burton | Mobile wearable monitoring systems |
SG11201707030QA (en) | 2015-03-02 | 2017-09-28 | Kaio Therapy Llc | Systems and methods for providing alternating magnetic field therapy |
WO2017004156A1 (en) * | 2015-06-30 | 2017-01-05 | University Of Maryland, Baltimore | Methods and systems for controlling magnetic fields and magnetic field induced current |
WO2016168377A1 (en) | 2015-04-13 | 2016-10-20 | Levita Magnetics International Corp. | Retractor systems, devices, and methods for use |
EP3282954B1 (en) | 2015-04-13 | 2021-07-28 | Levita Magnetics International Corp. | Grasper with magnetically-controlled positioning |
US11491342B2 (en) | 2015-07-01 | 2022-11-08 | Btl Medical Solutions A.S. | Magnetic stimulation methods and devices for therapeutic treatments |
US11266850B2 (en) | 2015-07-01 | 2022-03-08 | Btl Healthcare Technologies A.S. | High power time varying magnetic field therapy |
US10695575B1 (en) | 2016-05-10 | 2020-06-30 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
US20180001107A1 (en) | 2016-07-01 | 2018-01-04 | Btl Holdings Limited | Aesthetic method of biological structure treatment by magnetic field |
US11253717B2 (en) | 2015-10-29 | 2022-02-22 | Btl Healthcare Technologies A.S. | Aesthetic method of biological structure treatment by magnetic field |
US20170140657A1 (en) * | 2015-11-09 | 2017-05-18 | Black Swift Technologies LLC | Augmented reality to display flight data and locate and control an aerial vehicle in real time |
GB2549762A (en) * | 2016-04-28 | 2017-11-01 | The Magstim Company Ltd | Magnetic stimulation coil arrangement |
US11464993B2 (en) | 2016-05-03 | 2022-10-11 | Btl Healthcare Technologies A.S. | Device including RF source of energy and vacuum system |
US11247039B2 (en) | 2016-05-03 | 2022-02-15 | Btl Healthcare Technologies A.S. | Device including RF source of energy and vacuum system |
US11534619B2 (en) | 2016-05-10 | 2022-12-27 | Btl Medical Solutions A.S. | Aesthetic method of biological structure treatment by magnetic field |
US10583287B2 (en) | 2016-05-23 | 2020-03-10 | Btl Medical Technologies S.R.O. | Systems and methods for tissue treatment |
US10556122B1 (en) | 2016-07-01 | 2020-02-11 | Btl Medical Technologies S.R.O. | Aesthetic method of biological structure treatment by magnetic field |
WO2018089795A1 (en) | 2016-11-10 | 2018-05-17 | Qoravita LLC | System and method for applying a low frequency magnetic field to biological tissues |
US11020137B2 (en) | 2017-03-20 | 2021-06-01 | Levita Magnetics International Corp. | Directable traction systems and methods |
CA3065786C (en) * | 2017-05-30 | 2021-01-26 | Firstech, LLC | Vehicle key locker |
JP6905884B2 (en) * | 2017-07-20 | 2021-07-21 | 株式会社テイエルブイ | probe |
IL253677B2 (en) | 2017-07-26 | 2023-06-01 | Epitech Mag Ltd | Magnetic device for treating living tissues |
FR3073148B1 (en) | 2017-11-07 | 2021-04-09 | G C Tech | PORTABLE DEVICE TO GENERATE LOW FREQUENCY SINUSOIDAL INDUCED ELECTRIC CURRENT |
JP2021513449A (en) * | 2018-02-06 | 2021-05-27 | シュティミッツ アクチエンゲゼルシャフト | Ventilator and how to ventilate the patient |
US11000693B2 (en) | 2018-02-20 | 2021-05-11 | Neuronetics, Inc. | Magnetic stimulation coils and ferromagnetic components for treatment and diagnostic procedures |
EP3755422A4 (en) * | 2018-02-20 | 2021-09-29 | Neuronetics, Inc. | Magnetic stimulation coils and ferromagnetic components for treatment and diagnostic procedures |
US11406711B2 (en) * | 2018-04-20 | 2022-08-09 | UNandUP, LLC. | System and method for conveyance of therapeutic agents using a configurable magnetic field |
CN112218680A (en) * | 2018-06-28 | 2021-01-12 | 株式会社Ifg | Magnetic stimulation device |
CN109171949A (en) * | 2018-09-11 | 2019-01-11 | 璿鉴精密电子科技(苏州)有限公司 | A kind of magnetic field induction thermotherapeutic apparatus |
JP2020048985A (en) * | 2018-09-27 | 2020-04-02 | スミダコーポレーション株式会社 | Organism stimulating magnetic field generating device |
JP7200586B2 (en) * | 2018-10-09 | 2023-01-10 | スミダコーポレーション株式会社 | Magnetic field generator for biostimulation |
SI3721939T1 (en) | 2019-04-11 | 2022-10-28 | Btl Healthcare Technologies A.S. | Device for aesthetic treatment of biological structures by radiofrequency and magnetic energy |
US11160884B2 (en) * | 2019-05-14 | 2021-11-02 | Sabanci Universitesi | Alternating current magnet system for magnet-assisted transfection |
EP4088778B1 (en) * | 2020-01-08 | 2024-03-06 | IFG Corporation | Magnetic stimulator |
US11878167B2 (en) | 2020-05-04 | 2024-01-23 | Btl Healthcare Technologies A.S. | Device and method for unattended treatment of a patient |
BR112022022112A2 (en) | 2020-05-04 | 2022-12-13 | Btl Healthcare Tech A S | DEVICE FOR UNASSISTED PATIENT TREATMENT |
US11896816B2 (en) | 2021-11-03 | 2024-02-13 | Btl Healthcare Technologies A.S. | Device and method for unattended treatment of a patient |
WO2023250169A1 (en) | 2022-06-24 | 2023-12-28 | Neuronetics, Inc. | Motor threshold detection device for use with a magnetic stimulation system |
US11730969B1 (en) | 2022-10-12 | 2023-08-22 | Ampa Inc. | Transcranial magnetic stimulation system and method |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5725471A (en) * | 1994-11-28 | 1998-03-10 | Neotonus, Inc. | Magnetic nerve stimulator for exciting peripheral nerves |
US20040077923A1 (en) * | 2001-02-08 | 2004-04-22 | Aaron Frimerman | Control of body electrical activity by magnetic fields |
Family Cites Families (178)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH393535A (en) | 1961-09-26 | 1965-06-15 | Trueb Taeuber & Co Ag | Magnet arrangement for generating magnetic fields of variable field strength with constant geometric configuration |
US3658051A (en) | 1967-11-13 | 1972-04-25 | Kenneth Sheldon Maclean | Method of treating living things using high intensity pulsed magnetic field |
US3683923A (en) | 1970-09-25 | 1972-08-15 | Valleylab Inc | Electrosurgery safety circuit |
US3848331A (en) | 1973-09-11 | 1974-11-19 | Westinghouse Electric Corp | Method of producing molded stators from steel particles |
JPS5437679B2 (en) | 1974-04-26 | 1979-11-16 | ||
US4156882A (en) * | 1977-12-15 | 1979-05-29 | Texas Instruments Incorporated | Magnetic transducer |
US4638798A (en) | 1980-09-10 | 1987-01-27 | Shelden C Hunter | Stereotactic method and apparatus for locating and treating or removing lesions |
US4473074A (en) | 1981-09-28 | 1984-09-25 | Xanar, Inc. | Microsurgical laser device |
US4601765A (en) * | 1983-05-05 | 1986-07-22 | General Electric Company | Powdered iron core magnetic devices |
US4601753A (en) | 1983-05-05 | 1986-07-22 | General Electric Company | Powdered iron core magnetic devices |
GB8406509D0 (en) | 1984-03-13 | 1984-04-18 | Bio Medical Res Ltd | Electrical stimulation of muscle |
JPS61112310A (en) | 1984-11-07 | 1986-05-30 | Sumitomo Bakelite Co Ltd | Manufacture of permanent magnet |
JPS6243113A (en) | 1985-08-21 | 1987-02-25 | Toshiba Corp | Sintered magnetic core |
JPS6243113U (en) | 1985-09-04 | 1987-03-16 | ||
US5116304A (en) | 1987-01-28 | 1992-05-26 | Cadwell Industries, Inc. | Magnetic stimulator with skullcap-shaped coil |
US4994015A (en) | 1987-09-14 | 1991-02-19 | Cadwell Industries, Inc. | Magnetic stimulator coils |
GB8728150D0 (en) | 1987-12-02 | 1988-01-06 | Inst Of Neurology Queen Square | Head fixation apparatus |
DE3804491A1 (en) | 1987-12-02 | 1989-06-15 | Olympus Optical Co | Device for brain surgery |
US5160447A (en) | 1988-02-29 | 1992-11-03 | Kabushiki Kaisha Sankyo Seiki Seisakusho | Compressed powder magnetic core and method for fabricating same |
JP2692834B2 (en) | 1988-02-29 | 1997-12-17 | 株式会社三協精機製作所 | Dust core |
FI83266C (en) | 1988-09-12 | 1991-06-10 | Teknillinen Korkeakoulu | FOERFARANDE OCH ANORDNING FOER LOKALISERING AV ELEKTRODER FAESTADE VID KROPPEN AV EN MAENNISKA, I SYNNERHET HUVUDET. |
US5078674A (en) | 1989-02-10 | 1992-01-07 | Cadwll Industries, Inc. | Magnetic stimulator coils |
US5063011A (en) | 1989-06-12 | 1991-11-05 | Hoeganaes Corporation | Doubly-coated iron particles |
US5306524A (en) | 1989-06-12 | 1994-04-26 | Hoeganaes Corporation | Thermoplastic coated magnetic powder compositions and methods of making same |
US5097833A (en) | 1989-09-19 | 1992-03-24 | Campos James M | Transcutaneous electrical nerve and/or muscle stimulator |
US5178757A (en) * | 1990-06-29 | 1993-01-12 | Mag-Well, Inc. | Magnetic, fluid-conditioning tools |
US5299569A (en) | 1991-05-03 | 1994-04-05 | Cyberonics, Inc. | Treatment of neuropsychiatric disorders by nerve stimulation |
US5211896A (en) | 1991-06-07 | 1993-05-18 | General Motors Corporation | Composite iron material |
US5268438A (en) | 1991-09-06 | 1993-12-07 | Rohm And Haas Company | Aromatic polyester melt strength improver |
US5268140A (en) | 1991-10-03 | 1993-12-07 | Hoeganaes Corporation | Thermoplastic coated iron powder components and methods of making same |
US5254123A (en) | 1992-02-24 | 1993-10-19 | Complete System Diagnostics, Inc. | Compressive device for ultrasound-guided repair of pseudoaneurysms |
JPH0641376U (en) | 1992-10-23 | 1994-05-31 | 国産電機株式会社 | Self-excited field rotating AC generator |
FI98337C (en) | 1992-11-30 | 1997-06-10 | Risto Juhani Ilmoniemi | Method and apparatus for distinguishing between brain excitation responses and spontaneous function and different components of signals measured from the heart |
US6117066A (en) | 1992-12-04 | 2000-09-12 | Somatics, Inc. | Prevention of seizure arising from medical magnetoictal non-convulsive stimulation therapy |
US5813970A (en) | 1992-12-04 | 1998-09-29 | Somatics, Inc. | Medical magnetoictal therapy |
WO1994028815A1 (en) | 1993-06-15 | 1994-12-22 | Mitaka Kohki Co., Ltd. | Stand for optical device |
US5898253A (en) | 1993-11-18 | 1999-04-27 | General Motors Corporation | Grain oriented composite soft magnetic structure |
US5370117A (en) | 1994-01-03 | 1994-12-06 | Mclaurin, Jr.; Robert L. | Immobilization system for repeated use in imaging and treating of brain tumors |
US5769778A (en) | 1994-04-22 | 1998-06-23 | Somatics, Inc. | Medical magnetic non-convulsive stimulation therapy |
US6425852B1 (en) | 1994-11-28 | 2002-07-30 | Emory University | Apparatus and method for transcranial magnetic brain stimulation, including the treatment of depression and the localization and characterization of speech arrest |
US6132361A (en) | 1994-11-28 | 2000-10-17 | Neotonus, Inc. | Transcranial brain stimulation |
US6086525A (en) * | 1994-11-28 | 2000-07-11 | Neotonus, Inc. | Magnetic nerve stimulator for exciting peripheral nerves |
US6618614B1 (en) | 1995-01-03 | 2003-09-09 | Non-Invasive Technology, Inc. | Optical examination device, system and method |
US5566681A (en) | 1995-05-02 | 1996-10-22 | Manwaring; Kim H. | Apparatus and method for stabilizing a body part |
NZ333791A (en) | 1995-06-19 | 2000-09-29 | Robert R | Electronic apparatus, for treating pain by application of an electrical stimulus, comprising an electrode complex and a magnetic flux generator |
JPH10505286A (en) | 1995-06-20 | 1998-05-26 | シン ング、ワン | Articulated arm for medical procedures |
US5707334A (en) | 1995-08-21 | 1998-01-13 | Young; Robert B. | Method of treating amygdala related transitory disorders |
US6480743B1 (en) | 2000-04-05 | 2002-11-12 | Neuropace, Inc. | System and method for adaptive brain stimulation |
US6002251A (en) * | 1995-12-15 | 1999-12-14 | Sun; Yu-Shi | Electromagnetic-field-focusing remote-field eddy-current probe system and method for inspecting anomalies in conducting plates |
US5855582A (en) | 1995-12-19 | 1999-01-05 | Gildenberg; Philip L. | Noninvasive stereotactic apparatus and method for relating data between medical devices |
US6463328B1 (en) | 1996-02-02 | 2002-10-08 | Michael Sasha John | Adaptive brain stimulation method and system |
US5828770A (en) | 1996-02-20 | 1998-10-27 | Northern Digital Inc. | System for determining the spatial position and angular orientation of an object |
JP4187266B2 (en) | 1996-02-23 | 2008-11-26 | ホガナス アクチボラゲット | Phosphate-coated iron powder and method for producing the same |
CN1224367A (en) | 1996-04-26 | 1999-07-28 | 乌尔姆大学生物医学工程研究中心 | Method and apparatus for focused neuromagnetic stimulation and detection |
JPH1041119A (en) | 1996-07-24 | 1998-02-13 | Victor Co Of Japan Ltd | Bond magnetic body |
US6500110B1 (en) * | 1996-08-15 | 2002-12-31 | Neotonus, Inc. | Magnetic nerve stimulation seat device |
AU735591B2 (en) | 1996-08-15 | 2001-07-12 | Neotonus, Inc. | Transcranial brain stimulation |
FI964387A0 (en) | 1996-10-30 | 1996-10-30 | Risto Ilmoniemi | Foerfarande och anordning Foer kartlaeggning av kontakter inom hjaernbarken |
EP0850665B1 (en) | 1996-12-27 | 2004-03-03 | Nihon Kohden Corporation | Magnetic stimulus type urinary incontinence treatment coil apparatus |
US6057373A (en) | 1997-05-22 | 2000-05-02 | Synchroneuron, Llc | Methods of treating tardive dyskinesia and other movement disorders using NMDA receptor antagonists |
US5923417A (en) | 1997-09-26 | 1999-07-13 | Northern Digital Incorporated | System for determining the spatial position of a target |
CA2306918C (en) | 1997-10-17 | 2008-04-15 | Respironics, Inc. | Muscle stimulating device and method for diagnosing and treating a breathing disorder |
US6597954B1 (en) | 1997-10-27 | 2003-07-22 | Neuropace, Inc. | System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes |
JPH11144971A (en) | 1997-11-14 | 1999-05-28 | Matsushita Electric Ind Co Ltd | Coil parts and power supply using the same |
FI103384B1 (en) | 1997-11-28 | 1999-06-30 | Risto Ilmoniemi | Stimulation mandrel and method for attenuating the sound of a stimulator coil |
US6061644A (en) | 1997-12-05 | 2000-05-09 | Northern Digital Incorporated | System for determining the spatial position and orientation of a body |
US6074385A (en) | 1998-02-03 | 2000-06-13 | Kiefer Corp. | Hair follicle devitalization by induced heating of magnetically susceptible particles |
US6131361A (en) * | 1998-03-04 | 2000-10-17 | Murphy; James T. | Displaceable support bracket for drywall panel installation |
US6179771B1 (en) | 1998-04-21 | 2001-01-30 | Siemens Aktiengesellschaft | Coil arrangement for transcranial magnetic stimulation |
US6266556B1 (en) | 1998-04-27 | 2001-07-24 | Beth Israel Deaconess Medical Center, Inc. | Method and apparatus for recording an electroencephalogram during transcranial magnetic stimulation |
US6169963B1 (en) | 1998-06-02 | 2001-01-02 | Magnetherapy, Inc. | Magnetic field strength mapping system |
AUPP398898A0 (en) | 1998-06-09 | 1998-07-02 | University Of Queensland, The | Diagnostic method and apparatus |
JP3421944B2 (en) | 1998-06-10 | 2003-06-30 | 株式会社日立製作所 | Method and apparatus for manufacturing dust core |
US6198958B1 (en) | 1998-06-11 | 2001-03-06 | Beth Israel Deaconess Medical Center, Inc. | Method and apparatus for monitoring a magnetic resonance image during transcranial magnetic stimulation |
US6389318B1 (en) | 1998-07-06 | 2002-05-14 | Abiomed, Inc. | Magnetic shield for primary coil of transcutaneous energy transfer device |
FI105163B (en) | 1998-07-10 | 2000-06-30 | Juha Virtanen | Method and apparatus for generating placebo magnetic stimulation |
US6210317B1 (en) | 1998-07-13 | 2001-04-03 | Dean R. Bonlie | Treatment using oriented unidirectional DC magnetic field |
JP2000049008A (en) * | 1998-07-29 | 2000-02-18 | Tdk Corp | Ferromagnetic powder for dust core dust core, and its manufacture |
US6418345B1 (en) | 1998-08-03 | 2002-07-09 | Amei Technologies Inc. | PEMF stimulator for treating osteoporosis and stimulating tissue growth |
US7277758B2 (en) | 1998-08-05 | 2007-10-02 | Neurovista Corporation | Methods and systems for predicting future symptomatology in a patient suffering from a neurological or psychiatric disorder |
JP2000100617A (en) | 1998-09-25 | 2000-04-07 | Masaaki Yagi | Coil with core and pam-controlled air conditioner |
US6279579B1 (en) | 1998-10-23 | 2001-08-28 | Varian Medical Systems, Inc. | Method and system for positioning patients for medical treatment procedures |
US6505074B2 (en) | 1998-10-26 | 2003-01-07 | Birinder R. Boveja | Method and apparatus for electrical stimulation adjunct (add-on) treatment of urinary incontinence and urological disorders using an external stimulator |
US6366814B1 (en) | 1998-10-26 | 2002-04-02 | Birinder R. Boveja | External stimulator for adjunct (add-on) treatment for neurological, neuropsychiatric, and urological disorders |
US6253109B1 (en) | 1998-11-05 | 2001-06-26 | Medtronic Inc. | System for optimized brain stimulation |
US6155966A (en) | 1998-11-17 | 2000-12-05 | Parker; Lloyd S. | Apparatus and method for toning tissue with a focused, coherent electromagnetic field |
US6477410B1 (en) | 2000-05-31 | 2002-11-05 | Biophoretic Therapeutic Systems, Llc | Electrokinetic delivery of medicaments |
AU4505599A (en) | 1999-06-02 | 2000-12-28 | Medinova Medical Consulting Gmbh | Transcranial magnetic stimulation (tms) for improving vision in humans |
DE19937492C2 (en) | 1999-08-07 | 2001-08-23 | Mfh Hyperthermiesysteme Gmbh | Magnetic field applicator for heating magnetic or magnetizable substances or solids in biological tissue |
AU6790300A (en) | 1999-08-18 | 2001-03-13 | Children's Medical Center Corporation | Methods, compositions and kits for promoting recovery from damage to the central nervous system |
US6516213B1 (en) | 1999-09-03 | 2003-02-04 | Robin Medical, Inc. | Method and apparatus to estimate location and orientation of objects during magnetic resonance imaging |
US6567702B1 (en) | 1999-10-15 | 2003-05-20 | The Board Of Trustees Of The Leland Stanford Junior University | Eliciting analgesia by transcranial electrical stimulation |
AU1213401A (en) | 1999-10-19 | 2001-04-30 | Johns Hopkins University, The | Techniques using heat flow management, stimulation, and signal analysis to treatmedical disorders |
US6288785B1 (en) | 1999-10-28 | 2001-09-11 | Northern Digital, Inc. | System for determining spatial position and/or orientation of one or more objects |
GB9926621D0 (en) | 1999-11-11 | 2000-01-12 | Magstim Co Ltd | Stimulating coil |
US6516288B2 (en) | 1999-12-22 | 2003-02-04 | Curtis A. Bagne | Method and system to construct action coordination profiles |
JP3670575B2 (en) | 2000-01-12 | 2005-07-13 | Tdk株式会社 | Method for manufacturing coil-enclosed dust core and coil-enclosed dust core |
US6553326B1 (en) | 2000-04-07 | 2003-04-22 | Northern Digital Inc. | Errors in systems using magnetic fields to locate objects |
JP2001293098A (en) | 2000-04-14 | 2001-10-23 | Nippon Koden Corp | Coil device and coil driving device |
US6413263B1 (en) | 2000-04-24 | 2002-07-02 | Axon Instruments, Inc. | Stereotactic probe holder and method of use |
US20020097125A1 (en) * | 2000-06-05 | 2002-07-25 | Kent Davey | Method for optimizing transcranial magnetic stimulation cores and magnetic cores produced thereby |
AU2001268473A1 (en) | 2000-06-20 | 2002-01-02 | Advanced Bionics Corporation | Apparatus for treatment of mood and/or anxiety disorders by electrical brain stimulation and/or drug infusion |
JP2002015912A (en) | 2000-06-30 | 2002-01-18 | Tdk Corp | Dust core powder and dust core |
US7756584B2 (en) | 2000-07-13 | 2010-07-13 | Advanced Neuromodulation Systems, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US20030125786A1 (en) | 2000-07-13 | 2003-07-03 | Gliner Bradford Evan | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US7146217B2 (en) | 2000-07-13 | 2006-12-05 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a change in a neural-function of a patient |
US7831305B2 (en) | 2001-10-15 | 2010-11-09 | Advanced Neuromodulation Systems, Inc. | Neural stimulation system and method responsive to collateral neural activity |
US7024247B2 (en) | 2001-10-15 | 2006-04-04 | Northstar Neuroscience, Inc. | Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures |
US7010351B2 (en) | 2000-07-13 | 2006-03-07 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
US6497648B1 (en) | 2000-07-18 | 2002-12-24 | Omar Vicente Rey | Device for applying electromagnetic therapy |
US6402678B1 (en) | 2000-07-31 | 2002-06-11 | Neuralieve, Inc. | Means and method for the treatment of migraine headaches |
US6591138B1 (en) | 2000-08-31 | 2003-07-08 | Neuropace, Inc. | Low frequency neurostimulator for the treatment of neurological disorders |
US6560490B2 (en) | 2000-09-26 | 2003-05-06 | Case Western Reserve University | Waveforms for selective stimulation of central nervous system neurons |
AU2002213057A1 (en) | 2000-10-10 | 2002-04-22 | Curtis A. Bagne | Method and system to construct action coordination profiles |
US6488617B1 (en) | 2000-10-13 | 2002-12-03 | Universal Hedonics | Method and device for producing a desired brain state |
JP2004511314A (en) | 2000-10-20 | 2004-04-15 | アメリカ合衆国 | Coil for magnetic stimulation and method of using the same |
US20020103515A1 (en) | 2000-12-01 | 2002-08-01 | Kent Davey | Magnetic fields for the treatment of cancer and to assist in nerve regeneration |
US6641520B2 (en) | 2001-01-29 | 2003-11-04 | Electro Magnetic Resources Corp. | Magnetic field generator for therapeutic applications |
US7829006B2 (en) | 2001-02-15 | 2010-11-09 | Integral Technologies, Inc. | Method to form vehicle component devices from conductive loaded resin-based materials |
US20020160436A1 (en) | 2001-03-14 | 2002-10-31 | Marko Markov | Method and apparatus for determining biologically useful field metrics associated with magnetic fields |
JP2003303711A (en) | 2001-03-27 | 2003-10-24 | Jfe Steel Kk | Iron base powder and dust core using the same, and method of manufacturing iron base powder |
US6572528B2 (en) | 2001-04-20 | 2003-06-03 | Mclean Hospital Corporation | Magnetic field stimulation techniques |
US6650936B2 (en) | 2001-04-23 | 2003-11-18 | Medtronic Physio-Control Manufacturing Corporation. | Method and apparatus for delivering electrotherapy having an equivalent probability of success for different patients |
US7087008B2 (en) | 2001-05-04 | 2006-08-08 | Board Of Regents, The University Of Texas System | Apparatus and methods for delivery of transcranial magnetic stimulation |
US20030087264A1 (en) | 2001-05-22 | 2003-05-08 | Kaplitt Michael G. | Transcriptional regulation of target genes |
US6625563B2 (en) | 2001-06-26 | 2003-09-23 | Northern Digital Inc. | Gain factor and position determination system |
ES2238365T3 (en) | 2001-06-28 | 2005-09-01 | Brainlab Ag | TRANSCRANEAL MAGNETIC STIMULATION DEVICE. |
EP1269913B1 (en) | 2001-06-28 | 2004-08-04 | BrainLAB AG | Device for transcranial magnetic stimulation and cortical cartography |
US6551233B2 (en) | 2001-08-08 | 2003-04-22 | R. B. Carr Engineering, Onc. | Magnetic stimulator power and control circuit |
AU2002330165A1 (en) | 2001-09-28 | 2003-05-06 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
WO2003026738A1 (en) | 2001-09-28 | 2003-04-03 | Northstar Neuroscience, Inc. | Methods and apparatus for electrically stimulating cells implanted in the nervous system |
FI114613B (en) | 2001-10-17 | 2004-11-30 | Nexstim Oy | Method and apparatus for dose calculation of magnetic stimulation |
US6944497B2 (en) | 2001-10-31 | 2005-09-13 | Medtronic, Inc. | System and method of treating stuttering by neuromodulation |
AU2002354041A1 (en) | 2001-11-06 | 2003-05-19 | John L. Haracz | Antimnemonic therapy for hypermemory syndromes |
US6978179B1 (en) | 2002-02-27 | 2005-12-20 | Flagg Rodger H | Method and apparatus for magnetic brain wave stimulation |
AU2003218433A1 (en) | 2002-03-25 | 2003-10-13 | Musc Foundation For Research Development | Methods and systems for using transcranial magnetic stimulation to enhance cognitive performance |
US20050124848A1 (en) | 2002-04-05 | 2005-06-09 | Oliver Holzner | Method and apparatus for electromagnetic modification of brain activity |
JP2005528937A (en) | 2002-04-05 | 2005-09-29 | ホルツナー、オリヴァー | Method and apparatus for electromagnetic correction of brain activity |
DE10215115A1 (en) | 2002-04-05 | 2003-10-16 | Oliver Holzner | Method and device for the prevention of epileptic seizures |
US20030195588A1 (en) | 2002-04-16 | 2003-10-16 | Neuropace, Inc. | External ear canal interface for the treatment of neurological disorders |
US20030236457A1 (en) | 2002-04-24 | 2003-12-25 | Mericle Robert A. | Method of endovascular brain mapping |
US7283861B2 (en) | 2002-04-30 | 2007-10-16 | Alexander Bystritsky | Methods for modifying electrical currents in neuronal circuits |
WO2003098268A1 (en) | 2002-05-17 | 2003-11-27 | Musc Foundation For Research Development | Method, apparatus, and system for automatically positioning a probe or sensor |
US20060173274A1 (en) | 2002-07-15 | 2006-08-03 | George Mark S | Functional magnetic resonance imaging guided transcranial magnetic stimulation deception inhibitor |
US7471974B2 (en) | 2002-09-13 | 2008-12-30 | Brainlab Ag | Method for planning stimulation of hyper/hypometabolic cortical areas |
US20040051279A1 (en) | 2002-09-17 | 2004-03-18 | Grant William M. | Mobile elevating chair apparatus |
US7599737B2 (en) | 2002-10-04 | 2009-10-06 | Microchips, Inc. | Medical device for neural stimulation and controlled drug delivery |
FI113615B (en) | 2002-10-17 | 2004-05-31 | Nexstim Oy | Three-dimensional modeling of skull shape and content |
US6899667B2 (en) | 2002-10-21 | 2005-05-31 | Paul F. Becker | Method and apparatus for the treatment of physical and mental disorders with low frequency, low flux density magnetic fields |
US7367936B2 (en) | 2002-11-21 | 2008-05-06 | The Magstim Company Ltd. | Magnetic stimulators and coils therefor |
US7294101B2 (en) | 2002-12-21 | 2007-11-13 | Neuropace, Inc. | Means and methods for treating headaches |
JP2004209096A (en) | 2003-01-07 | 2004-07-29 | Olympus Corp | Medical instrument holding device |
JP4270889B2 (en) | 2003-01-15 | 2009-06-03 | オリンパス株式会社 | Medical instrument holding device |
US7771341B2 (en) | 2003-01-22 | 2010-08-10 | William Thomas Rogers | Electromagnetic brain animation |
JP2004237050A (en) | 2003-02-06 | 2004-08-26 | Takahiro Hara | Warming device |
JP2004253434A (en) | 2003-02-18 | 2004-09-09 | Matsushita Electric Ind Co Ltd | Coil component and power supply device using it |
WO2004075976A2 (en) | 2003-02-25 | 2004-09-10 | Spectragenics, Inc. | Method and apparatus for the treatment of benign pigmented lesions |
RU2235529C1 (en) * | 2003-02-26 | 2004-09-10 | Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им. акад. С.Н. Федорова | Surgical method for treating the cases of central retinal vein thrombosis |
RU2235527C1 (en) * | 2003-02-26 | 2004-09-10 | Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им. акад. С.Н. Федорова | Surgical method for treating the cases of ablatio retinae |
RU2230533C1 (en) * | 2003-02-26 | 2004-06-20 | Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им. акад. С.Н. Федорова | Magnetic implant for applying surgical treatment of central retinal vein thrombosis cases |
RU2235528C1 (en) * | 2003-02-26 | 2004-09-10 | Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им.акад. С.Н.Федорова | Surgical method for treating the cases of dystrophic diseases of retina and optic nerve |
US7153256B2 (en) | 2003-03-07 | 2006-12-26 | Neuronetics, Inc. | Reducing discomfort caused by electrical stimulation |
US20060199992A1 (en) | 2003-03-17 | 2006-09-07 | Eisenberg Solomon R | Magnetic stimulator |
JP2004288437A (en) | 2003-03-20 | 2004-10-14 | Fuji Xerox Co Ltd | Exciting coil, core, and image forming apparatus |
US6954060B1 (en) * | 2003-03-28 | 2005-10-11 | Edel Thomas G | a-c current transformer functional with a d-c current component present |
BRPI0410296A (en) | 2003-05-06 | 2006-05-16 | Aspect Medical Systems Inc | system and method for determining the efficacy of treatment of neurological disorders using electroencephalogram |
US7706871B2 (en) | 2003-05-06 | 2010-04-27 | Nellcor Puritan Bennett Llc | System and method of prediction of response to neurological treatment using the electroencephalogram |
EP1638647A1 (en) | 2003-06-27 | 2006-03-29 | Fralex Therapeutics Inc. | System for image-guided pulsed magnetic field diagnosis and treatment |
RU2248821C1 (en) * | 2003-07-08 | 2005-03-27 | Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им. акад. С.Н. Федорова | Surgical method for treating premature newborns for retinopathy |
JP4257846B2 (en) | 2003-12-08 | 2009-04-22 | 日立金属株式会社 | Method for producing soft magnetic compact |
US7422555B2 (en) | 2003-12-30 | 2008-09-09 | Jacob Zabara | Systems and methods for therapeutically treating neuro-psychiatric disorders and other illnesses |
US7651459B2 (en) | 2004-01-06 | 2010-01-26 | Neuronetics, Inc. | Method and apparatus for coil positioning for TMS studies |
US7520848B2 (en) | 2004-04-09 | 2009-04-21 | The Board Of Trustees Of The Leland Stanford Junior University | Robotic apparatus for targeting and producing deep, focused transcranial magnetic stimulation |
US8177702B2 (en) | 2004-04-15 | 2012-05-15 | Neuronetics, Inc. | Method and apparatus for determining the proximity of a TMS coil to a subject's head |
US20060113696A1 (en) | 2004-07-12 | 2006-06-01 | Integral Technologies, Inc. | Low cost vehicle fuel system components manufactured from conductive loaded resin-based materials |
US7685706B2 (en) * | 2005-07-08 | 2010-03-30 | Semiconductor Energy Laboratory Co., Ltd | Method of manufacturing a semiconductor device |
US7824324B2 (en) * | 2005-07-27 | 2010-11-02 | Neuronetics, Inc. | Magnetic core for medical procedures |
WO2008070001A2 (en) | 2006-12-01 | 2008-06-12 | Beth Israel Deaconess Medical Center, Inc. | Transcranial magnetic stimulation (tms) methods and apparatus |
-
2005
- 2005-07-27 US US11/191,106 patent/US7824324B2/en active Active
- 2005-08-26 US US11/213,415 patent/US7963903B2/en active Active
-
2006
- 2006-01-04 US US11/325,660 patent/US7560058B2/en active Active
- 2006-07-26 ES ES06788702.6T patent/ES2665912T3/en active Active
- 2006-07-26 DK DK17205912.3T patent/DK3332837T3/en active
- 2006-07-26 AU AU2006275713A patent/AU2006275713B2/en active Active
- 2006-07-26 EP EP17205912.3A patent/EP3332837B1/en active Active
- 2006-07-26 JP JP2008524159A patent/JP2009502350A/en active Pending
- 2006-07-26 WO PCT/US2006/029266 patent/WO2007016279A2/en active Application Filing
- 2006-07-26 ES ES17205912T patent/ES2796659T3/en active Active
- 2006-07-26 DK DK06788702.6T patent/DK1912699T3/en active
- 2006-07-26 EP EP06788702.6A patent/EP1912699B1/en active Active
- 2006-07-26 CA CA2617033A patent/CA2617033C/en active Active
-
2009
- 2009-06-05 US US12/479,076 patent/US9308386B2/en active Active
- 2009-06-05 US US12/479,069 patent/US8657731B2/en active Active
-
2010
- 2010-09-29 US US12/892,980 patent/US8246529B2/en active Active
-
2013
- 2013-02-07 JP JP2013022564A patent/JP2013078700A/en active Pending
-
2014
- 2014-06-04 JP JP2014116247A patent/JP2014176750A/en active Pending
-
2015
- 2015-12-29 US US14/982,739 patent/US9931518B2/en active Active
-
2016
- 2016-05-19 JP JP2016100770A patent/JP2016144757A/en active Pending
-
2018
- 2018-02-05 JP JP2018018556A patent/JP2018065025A/en active Pending
- 2018-02-21 US US15/901,853 patent/US10617884B2/en active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5725471A (en) * | 1994-11-28 | 1998-03-10 | Neotonus, Inc. | Magnetic nerve stimulator for exciting peripheral nerves |
US20040077923A1 (en) * | 2001-02-08 | 2004-04-22 | Aaron Frimerman | Control of body electrical activity by magnetic fields |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008200205A (en) * | 2007-02-19 | 2008-09-04 | Kanazawa Univ | Magnetic field generator for bone disorder treatment and evaluation and development system of bone disorder treatment using the same |
DE112008004049T5 (en) | 2008-10-31 | 2012-06-06 | Nexstim Oy, | Magnetic stimulation coils with electrically conductive structures |
US10232187B2 (en) | 2014-02-14 | 2019-03-19 | Osaka University | Coil device and transcranial magnetic stimulation system |
IT201600092729A1 (en) * | 2016-09-14 | 2018-03-14 | Policlinico San Donato S P A Istituto Di Ricovero E Cura A Carattere Scient | Method and system for modulating brain electrical activity |
WO2018051263A1 (en) * | 2016-09-14 | 2018-03-22 | Policlinico San Donato S.P.A. - Istituto Di Ricovero E Cura A Carattere Scientifico | Method and system for modulating the brain electrical activity |
US11077315B2 (en) | 2016-09-14 | 2021-08-03 | Policlinico San Donato S.P.A.—Istituto Di Ricovero E Cura A Carattere Scientifico | Method and system for modulating the brain electrical activity |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US10617884B2 (en) | Magnetic core for medical procedures | |
US11185710B2 (en) | Ferrofluidic cooling and acoustical noise reduction in magnetic stimulators | |
EP1807154B1 (en) | Reduction of discomfort using nerve stimulation | |
CA2689623C (en) | Drive circuit for magnetic stimulation | |
JP2009502350A5 (en) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DPE1 | Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101) | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2008524159 Country of ref document: JP |
|
ENP | Entry into the national phase |
Ref document number: 2617033 Country of ref document: CA |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2006275713 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2006788702 Country of ref document: EP |
|
ENP | Entry into the national phase |
Ref document number: 2006275713 Country of ref document: AU Date of ref document: 20060726 Kind code of ref document: A |