WO2006044342A2 - Self-gelling alginate systems and uses thereof - Google Patents
Self-gelling alginate systems and uses thereof Download PDFInfo
- Publication number
- WO2006044342A2 WO2006044342A2 PCT/US2005/036460 US2005036460W WO2006044342A2 WO 2006044342 A2 WO2006044342 A2 WO 2006044342A2 US 2005036460 W US2005036460 W US 2005036460W WO 2006044342 A2 WO2006044342 A2 WO 2006044342A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- alginate
- gelling
- gel
- dispersion
- insoluble
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
- A23L29/256—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/729—Agar; Agarose; Agaropectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/734—Alginic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Developmental Biology & Embryology (AREA)
- Dispersion Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MX2007004261A MX2007004261A (en) | 2004-10-12 | 2005-10-12 | Self-gelling alginate systems and uses thereof. |
EP05803188.1A EP1799232B1 (en) | 2004-10-12 | 2005-10-12 | Self-gelling alginate systems and uses thereof |
AU2005295927A AU2005295927B2 (en) | 2004-10-12 | 2005-10-12 | Self-gelling alginate systems and uses thereof |
BRPI0515973A BRPI0515973B8 (en) | 2004-10-12 | 2005-10-12 | kit to produce an alginate gel, composition to prepare a gel and use |
BR122018068450A BR122018068450B8 (en) | 2004-10-12 | 2005-10-12 | implantable device comprising alginate gel |
CN2005800415278A CN101227913B (en) | 2004-10-12 | 2005-10-12 | Self-gelling alginate systems and uses thereof |
CA2583373A CA2583373C (en) | 2004-10-12 | 2005-10-12 | Self-gelling alginate systems and uses thereof |
JP2007535898A JP5367266B2 (en) | 2004-10-12 | 2005-10-12 | Self-gelling alginate system and use thereof |
IL182426A IL182426A0 (en) | 2004-10-12 | 2007-04-10 | Self-gelling alginate systems and uses thereof |
NO20072013A NO341594B1 (en) | 2004-10-12 | 2007-04-19 | Biomedical kit for preparing a biocompatible alginate gel, composition for preparing such gels, method for dispensing a self-gelling alginate dispersion and an implantable device, and alginate gels and implantable devices comprising such |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61785204P | 2004-10-12 | 2004-10-12 | |
US60/617,852 | 2004-10-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006044342A2 true WO2006044342A2 (en) | 2006-04-27 |
WO2006044342A3 WO2006044342A3 (en) | 2007-12-06 |
Family
ID=36203445
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2005/036460 WO2006044342A2 (en) | 2004-10-12 | 2005-10-12 | Self-gelling alginate systems and uses thereof |
Country Status (12)
Country | Link |
---|---|
US (4) | US7790699B2 (en) |
EP (1) | EP1799232B1 (en) |
JP (1) | JP5367266B2 (en) |
CN (1) | CN101227913B (en) |
AU (1) | AU2005295927B2 (en) |
BR (2) | BRPI0515973B8 (en) |
CA (1) | CA2583373C (en) |
IL (1) | IL182426A0 (en) |
MX (1) | MX2007004261A (en) |
NO (1) | NO341594B1 (en) |
RU (1) | RU2393867C2 (en) |
WO (1) | WO2006044342A2 (en) |
Cited By (23)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2007148197A3 (en) * | 2006-06-21 | 2008-03-13 | Fmc Biopolymer As | Gastro-activated dietary fibers |
WO2008102855A1 (en) | 2007-02-21 | 2008-08-28 | Mochida Pharmaceutical Co., Ltd. | Composition for treatment of cartilage disease |
WO2008157285A1 (en) | 2007-06-13 | 2008-12-24 | Fmc Corporation | Biopolymer based implantable degradable devices |
EP2051748A2 (en) * | 2006-09-08 | 2009-04-29 | Symphony Medical, INC. | Intramyocardial patterning for global cardiac resizing and reshaping |
WO2009054181A1 (en) | 2007-10-24 | 2009-04-30 | Mochida Pharmaceutical Co., Ltd. | Composition for treatment of joint disease |
EP2082755A1 (en) | 2008-01-16 | 2009-07-29 | CellMed AG | Monolithic alginate implants networked in situ |
JP2009537268A (en) * | 2006-05-22 | 2009-10-29 | ユニヴァーシタ デグリ ステュディ デイ トリエステ | Hydrogels of polysaccharide mixtures for tissue engineering and as active compound carriers |
WO2010109588A1 (en) * | 2009-03-23 | 2010-09-30 | 財団法人函館地域産業振興財団 | Polymeric material for medical use and for basic makeup (for skin care) and process for producing same |
WO2010117266A1 (en) | 2009-04-06 | 2010-10-14 | Broockeville Corporation N.V. | In situ gelling alginate systems |
DE102010009475A1 (en) * | 2010-02-26 | 2011-09-01 | F. Holzer Gmbh | Process for the preparation of a dosable ready-to-use preparation |
WO2011112082A1 (en) | 2010-03-11 | 2011-09-15 | Bender Analytical Holding B.V. | Sterile alginate-based aqueous composition for medical use and process for the preparation thereof |
US8367637B2 (en) | 2008-08-19 | 2013-02-05 | Mochida Pharmaceutical Co., Ltd. | Composition for treating arthritic disorder |
WO2013039380A1 (en) | 2011-09-15 | 2013-03-21 | Bender Analytical Holding B.V. | Sterile alginate-based aqueous composition for medical use and process for the preparation thereof |
AU2013204006B2 (en) * | 2007-02-21 | 2015-09-17 | Mochida Pharmaceutical Co., Ltd | Composition for treatment of cartilage disease |
US9504643B2 (en) | 2010-03-29 | 2016-11-29 | Evonik Corporation | Compositions and methods for improved retention of a pharmaceutical composition at a local administration site |
US9795714B2 (en) | 2013-12-24 | 2017-10-24 | Ares Trading S.A. | FGF-18 formulation in alginate/collagen hydrogels |
WO2020096281A1 (en) * | 2018-11-06 | 2020-05-14 | 국립암센터 | Alginic acid-based injectable hydrogel system |
CN111491515A (en) * | 2017-08-31 | 2020-08-04 | 罗利制品有限公司 | Sugar-free edible container |
WO2020181405A1 (en) * | 2019-03-08 | 2020-09-17 | L'oreal | Kit for caring for the skin |
FR3110850A1 (en) * | 2020-04-30 | 2021-12-03 | L'oreal | SKIN CARE KIT |
WO2022047354A1 (en) | 2020-08-31 | 2022-03-03 | The Board Of Trustees Of The University Of Illinois | Alginate-coated mesenchymal stromal and progenitor cells and methods for using the same |
WO2023066994A1 (en) | 2021-10-21 | 2023-04-27 | Blue Wave Therapeutics Gmbh | Peptide-coupled alginate gels comprising radionuclides |
US11912856B2 (en) | 2021-06-23 | 2024-02-27 | Loliware, Inc. | Bio-based, biodegradable compositions and articles made therefrom |
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JP2008515434A (en) * | 2004-10-08 | 2008-05-15 | ジョージア テック リサーチ コーポレイション | Microencapsulation of cells in hydrogels using electrostatic potential |
AU2005295927B2 (en) * | 2004-10-12 | 2012-02-02 | Fmc Biopolymer As | Self-gelling alginate systems and uses thereof |
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CA2583373A1 (en) | 2006-04-27 |
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CN101227913B (en) | 2013-08-14 |
CA2583373C (en) | 2013-09-03 |
JP2008515927A (en) | 2008-05-15 |
BRPI0515973B8 (en) | 2021-07-27 |
BRPI0515973B1 (en) | 2018-11-21 |
BRPI0515973A (en) | 2008-08-12 |
US20140271576A1 (en) | 2014-09-18 |
JP5367266B2 (en) | 2013-12-11 |
US20060159823A1 (en) | 2006-07-20 |
IL182426A0 (en) | 2007-09-20 |
AU2005295927A1 (en) | 2006-04-27 |
AU2005295927B2 (en) | 2012-02-02 |
CN101227913A (en) | 2008-07-23 |
RU2007117702A (en) | 2008-11-20 |
US7790699B2 (en) | 2010-09-07 |
NO341594B1 (en) | 2017-12-11 |
MX2007004261A (en) | 2007-06-18 |
US9463162B2 (en) | 2016-10-11 |
NO20072013L (en) | 2007-07-06 |
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