WO2006028930A3 - Combinatorial artificial receptors including tether building blocks on scaffolds - Google Patents

Combinatorial artificial receptors including tether building blocks on scaffolds Download PDF

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Publication number
WO2006028930A3
WO2006028930A3 PCT/US2005/031213 US2005031213W WO2006028930A3 WO 2006028930 A3 WO2006028930 A3 WO 2006028930A3 US 2005031213 W US2005031213 W US 2005031213W WO 2006028930 A3 WO2006028930 A3 WO 2006028930A3
Authority
WO
WIPO (PCT)
Prior art keywords
scaffolds
building blocks
artificial receptors
receptors including
tether
Prior art date
Application number
PCT/US2005/031213
Other languages
French (fr)
Other versions
WO2006028930A2 (en
Inventor
Robert E Carlson
Original Assignee
Receptors Llc
Robert E Carlson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Receptors Llc, Robert E Carlson filed Critical Receptors Llc
Publication of WO2006028930A2 publication Critical patent/WO2006028930A2/en
Publication of WO2006028930A3 publication Critical patent/WO2006028930A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2600/00—Assays involving molecular imprinted polymers/polymers created around a molecular template

Abstract

The present invention relates to artificial receptors on scaffolds, methods of and compositions for making them, and methods of using them. Each artificial receptor includes a plurality of building block compounds coupled to a scaffold. In an embodiment, at least one of the building blocks includes a tether moiety. The tether can provide spacing or distance between the recognition element and the scaffold to which the building block is immobilized. A tether moiety can have any of a variety of characteristics or properties including flexibility, rigidity or stiffness, ability to bond to another tether moiety, and the like.
PCT/US2005/031213 2004-09-03 2005-09-01 Combinatorial artificial receptors including tether building blocks on scaffolds WO2006028930A2 (en)

Applications Claiming Priority (20)

Application Number Priority Date Filing Date Title
US60745804P 2004-09-03 2004-09-03
US60743804P 2004-09-03 2004-09-03
US60745704P 2004-09-03 2004-09-03
US60/607,458 2004-09-03
US60/607,438 2004-09-03
US60/607,457 2004-09-03
US60855704P 2004-09-10 2004-09-10
US60865404P 2004-09-10 2004-09-10
US60/608,654 2004-09-10
US60/608,557 2004-09-10
US60916004P 2004-09-11 2004-09-11
US60/609,160 2004-09-11
US61266604P 2004-09-23 2004-09-23
US60/612,666 2004-09-23
US62677004P 2004-11-10 2004-11-10
US60/626,770 2004-11-10
US64558205P 2005-01-19 2005-01-19
US60/645,582 2005-01-19
US64972905P 2005-02-03 2005-02-03
US60/649,729 2005-02-03

Publications (2)

Publication Number Publication Date
WO2006028930A2 WO2006028930A2 (en) 2006-03-16
WO2006028930A3 true WO2006028930A3 (en) 2006-05-26

Family

ID=35613667

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2005/031922 WO2006029234A1 (en) 2004-09-03 2005-09-01 Combinatorial artificial receptors including tether building blocks
PCT/US2005/031213 WO2006028930A2 (en) 2004-09-03 2005-09-01 Combinatorial artificial receptors including tether building blocks on scaffolds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2005/031922 WO2006029234A1 (en) 2004-09-03 2005-09-01 Combinatorial artificial receptors including tether building blocks

Country Status (3)

Country Link
US (3) US7884052B2 (en)
EP (1) EP1789797A1 (en)
WO (2) WO2006029234A1 (en)

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KR20120122869A (en) * 2009-06-02 2012-11-07 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases
TW201124726A (en) * 2009-10-16 2011-07-16 Univ Texas Compositions and methods for producing coded peptoid libraries
US20120241391A1 (en) * 2011-03-25 2012-09-27 Receptors Llc Filtration article with microbial removal, micro-biocidal, or static growth capability
JP2016528510A (en) * 2013-08-21 2016-09-15 ミカルティス エヌブイＭｙｃａｒｔｉｓ Ｎｖ Heterogeneous surface functionalization

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Also Published As

Publication number Publication date
WO2006029234A1 (en) 2006-03-16
WO2006028930A2 (en) 2006-03-16
US7504365B2 (en) 2009-03-17
US20090221439A1 (en) 2009-09-03
US7884052B2 (en) 2011-02-08
US20060205011A1 (en) 2006-09-14
US20060063205A1 (en) 2006-03-23
EP1789797A1 (en) 2007-05-30

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