WO2004082539A1 - Intragastric catheter - Google Patents
Intragastric catheter Download PDFInfo
- Publication number
- WO2004082539A1 WO2004082539A1 PCT/US2004/008049 US2004008049W WO2004082539A1 WO 2004082539 A1 WO2004082539 A1 WO 2004082539A1 US 2004008049 W US2004008049 W US 2004008049W WO 2004082539 A1 WO2004082539 A1 WO 2004082539A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bladder
- tubules
- stomach
- intragastric catheter
- neck
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
- A61F5/0013—Implantable devices or invasive measures
- A61F5/003—Implantable devices or invasive measures inflatable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/0003—Apparatus for the treatment of obesity; Anti-eating devices
- A61F5/0013—Implantable devices or invasive measures
- A61F5/0036—Intragastrical devices
- A61F5/004—Intragastrical devices remotely adjustable
Definitions
- This invention relates to medical devices generally, and is more specifically related to an intragastric catheter that is useful in the treatment of obesity.
- Morbid obesity is a major medical problem affecting millions of people. Many serious health problems are associated with morbid obesity, including hypertension, hyperlipidemia, exacerbation of diabetes mellitus, heart disease, degenerative arthritis, and Pickwickian syndrome, certain types of cancer, gallstones, varicose veins, thromboembolism and hernias. Additionally, morbid obesity can lead to psychosocial difficulties such as depression, loss of self-esteem and decreased employability.
- An intragastric catheter provides satiety due to its presence in the stomach cavity. Tactile sensation by a plurality of fingers that extend from the device provides satiety. Normal peristaltic action upon the device provides movement of the fingers relative to the stomach wall, reducing the likelihood of ulceration or necrosis.
- the structure of the intragastric catheter reduces the level of precision required in placement of the device, and the potential for blockage of conduits to and from the stomach by the device is reduced.
- Figure 1 is a perspective view of the intragastric catheter.
- Figure 2 is a sectioned view of the intragastric catheter, taken essentially along line 2-2 of Figure 1.
- Figure 3 is a side elevation of an intragastric catheter in the deflated state and positioned within a user's stomach.
- Figure 4 is a side elevation of an intragastric catheter in the inflated state and positioned within a user's stomach.
- Figure 5 is a side elevation of an intragastric catheter in the inflated state and positioned within a user's stomach.
- the intragastric catheter comprises a bladder 2.
- a plurality of finger-like tubules 3 extend from various locations on the lower surface of the bladder.
- a neck 4 connects a bolster to the bladder, and an external tube 6 extends from the internal bolster 8.
- External bolster 9 assists in holding the device in place within the stomach.
- the bladder contains a fluid 10.
- the fluid may be a gas, a liquid, or a gel, or a mixture thereof, or a combination thereof.
- the fluid is provided to the bladder through external tube 6. Increasing or decreasing the volume and pressure of fluid that is present in the chamber variably inflates the bladder.
- the finger-like tubules are hollow, with the hollow space in the tubules communicating with the bladder to provide for a transfer of fluid. Accordingly, as the bladder is filled with fluid, the fluid flows into tubules, providing additional rigidity for the tubules, according to the volume and pressure of the fluid that is present in the chamber.
- the chamber acts as a reservoir to supply fluid to the tubules.
- the tubules are flexible, and are capable of a deformation relative to the bladder. Particularly at the point of attachment of the tubules to the bladder, the tubules may be displaced relative to the bladder.
- the ends of the tubules that are opposite the bladder are dynamic. Movement of the tubules from peristaltic action provides a tactile sensation against the wall of the stomach, which provides satiety.
- the tubules may be variably inflated by the device as required, to provide the desired tactile stimulation. If the tubules are substantially deflated, so that they are flaccid, as shown in Figure 3, then little tactile stimulation will occur.
- the tubules have an enlarged end 16 that increases tactile stimulation.
- the enlarged end has a recess that is centrally disposed within the end. This recess in the end of the tubules helps reduce constant contact of the end of the tubules with the stomach wall by reducing the amount of surface area that comes in contact with the stomach wall.
- the neck 4 of the device is deformable, which insures proper orientation of the device relative to the stomach.
- Figure 5. The bolster 8 is adjacent to the stomach wall 12, while the neck allows the remainder of the device to bend relative to the bolster. Accordingly, if the device is positioned by a PEG procedure, and placement of the device is not optimal, the device deforms relative to bolster by means of the neck, so that the tubules contact the stomach wall. For example, if the placement is too high relative to optimal placement, the neck bends to allow the device to enter the relatively lower part of the stomach.
- Tubules 22 may be used to orient the device upon placement. As shown, tubules 22 from a higher point of the bladder when the device is positioned as in Figure 1. Tubules 22 extend from the bladder and opposite each other, and are generally horizontally when inflated and when the device is positioned as shown in Figure 1. These longer tubules help position the device. They are positioned by peristalsis and/or at placement so as to find the long axis of the stomach. If they are placed on the short axis, the stomach will move them to the position of least resistance.
- a valve is present where the tubule joins the bladder.
- the valve allows the tubule to be filled with fluid, but prevents fluid from returning to the chamber. In case of a leak in a particular tubule, the fluid will leak into the stomach from that tubule and it will become deflated. However, it is not necessary to replace the entire catheter as a result of the deflation of one, or a few, of the tubules, since the remainder of the device will remain inflated.
- the valves could be positioned within the tubules, near the end of the tubule that joins the bladder, or the valves could be positioned within the bladder near the entrance to the tubules.
- a diaphragm 22 is present within the bladder.
- the fluid pressure in the bladder is increased, the liquid pressure on the opposite side the diaphragm is increased, and the pressure and volume within the tubules is increased.
- handling and pressurizing a liquid or gel is more difficult for the patient, than is the application of air pressure. The patient may easily apply pressure to the device using an air pump, whereas attempting to pressurize a liquid or gel by the insertion of additional liquid or gel material under pressure is more difficult.
- the device may be constructed of suitable materials that will inflate or deflate when filled with a fluid.
- the device could be constructed of medical grade polyethylene terephthalate (PET). PET allows the device to have deformation characteristics similar to plastic storage bags that are commonly used in the kitchen, making it a suitable candidate for replacement by means of a percutaneous endoscopic gastrostomy (PEG) procedure as described herein.
- PET allows the device to have deformation characteristics similar to plastic storage bags that are commonly used in the kitchen, making it a suitable candidate for replacement by means of a percutaneous endoscopic gastrostomy (PEG) procedure as described herein.
- PEG percutaneous endoscopic gastrostomy
- the tubules may be formed of two or more plies of material. For example, a 2-ply tubule will have better resistant to breakage or puncture than will a single ply tubule.
- the intragastric catheter of the present invention may be introduced through the mouth, subsequently traveling through the esophagus and into the stomach.
- the abdominal wall is punctured, and a guide wire is inserted from the outside into the fundus of the stomach.
- the endoscope is grasped with the guide wire, and one end of the guide wire is extracted by pulling the endoscope out of the mouth while the other end of the guide wire remains outside of the abdomen.
- the intragastric catheter is placed through the abdominal wall by attaching the intragastric catheter to the guide wire extended out of the patient's mouth and pulling on the other end of the guide wire until the intragastric catheter is pulled through the puncture opening in the abdominal wall.
- the placed intragastric catheter is secured on the stomach wall with the bolster.
- Figures 3 through 5 show the intragastric catheter as it is positioned intragastrically within the obese person.
- the device is in position in the stomach, but is not inflated.
- Figure 4 shows the device positioned in the stomach as in Figure 3, and after inflation of the tubules.
- Figure 5 shows the device as inflated and in the stomach, with the neck 4 of the device providing deformation of the device within the stomach.
- the intragastric catheter has multiple finger like tubules that are subject to the peristalsis within the stomach, which causes movement of the tubules, and prevents pressure from being constantly applied on one surface of the stomach. Gastric erosion is thereby prevented.
- the tactile sensation provided by the finger like tubules against the stomach provides satiety, and suppresses the patient's appetite
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE602004015743T DE602004015743D1 (en) | 2003-03-17 | 2004-03-17 | INTRAGASTRIC CATHETER |
JP2006507245A JP2006520643A (en) | 2003-03-17 | 2004-03-17 | Intragastric catheter |
EP04757520A EP1603496B1 (en) | 2003-03-17 | 2004-03-17 | Intragastric catheter |
CA2517430A CA2517430C (en) | 2003-03-17 | 2004-03-17 | Intragastric catheter |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/390,947 US7291160B2 (en) | 2003-03-17 | 2003-03-17 | Intragastric catheter |
US10/390,947 | 2003-03-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004082539A1 true WO2004082539A1 (en) | 2004-09-30 |
WO2004082539A9 WO2004082539A9 (en) | 2005-04-14 |
Family
ID=32987603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/008049 WO2004082539A1 (en) | 2003-03-17 | 2004-03-17 | Intragastric catheter |
Country Status (7)
Country | Link |
---|---|
US (3) | US7291160B2 (en) |
EP (1) | EP1603496B1 (en) |
JP (1) | JP2006520643A (en) |
AT (1) | ATE404136T1 (en) |
CA (1) | CA2517430C (en) |
DE (1) | DE602004015743D1 (en) |
WO (1) | WO2004082539A1 (en) |
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- 2004-03-17 EP EP04757520A patent/EP1603496B1/en not_active Expired - Lifetime
- 2004-03-17 AT AT04757520T patent/ATE404136T1/en not_active IP Right Cessation
- 2004-03-17 DE DE602004015743T patent/DE602004015743D1/en not_active Expired - Lifetime
- 2004-03-17 WO PCT/US2004/008049 patent/WO2004082539A1/en active Application Filing
- 2004-03-17 JP JP2006507245A patent/JP2006520643A/en active Pending
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Also Published As
Publication number | Publication date |
---|---|
US20080071305A1 (en) | 2008-03-20 |
US20040186503A1 (en) | 2004-09-23 |
CA2517430A1 (en) | 2004-09-30 |
CA2517430C (en) | 2013-06-18 |
JP2006520643A (en) | 2006-09-14 |
US7223277B2 (en) | 2007-05-29 |
EP1603496B1 (en) | 2008-08-13 |
US7883525B2 (en) | 2011-02-08 |
US7291160B2 (en) | 2007-11-06 |
WO2004082539A9 (en) | 2005-04-14 |
ATE404136T1 (en) | 2008-08-15 |
US20050033345A1 (en) | 2005-02-10 |
EP1603496A1 (en) | 2005-12-14 |
DE602004015743D1 (en) | 2008-09-25 |
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