WO2004011365A3 - Micro-channel design features that facilitate centripetal fluid transfer - Google Patents

Micro-channel design features that facilitate centripetal fluid transfer Download PDF

Info

Publication number
WO2004011365A3
WO2004011365A3 PCT/US2003/022226 US0322226W WO2004011365A3 WO 2004011365 A3 WO2004011365 A3 WO 2004011365A3 US 0322226 W US0322226 W US 0322226W WO 2004011365 A3 WO2004011365 A3 WO 2004011365A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid transfer
features
micro
channel design
facilitate
Prior art date
Application number
PCT/US2003/022226
Other languages
French (fr)
Other versions
WO2004011365A2 (en
Inventor
Sean M Desmond
John Shigeura
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/336,274 external-priority patent/US7198759B2/en
Priority claimed from US10/336,706 external-priority patent/US7214348B2/en
Application filed by Applera Corp filed Critical Applera Corp
Priority to JP2005505600A priority Critical patent/JP2005533651A/en
Priority to EP03771636A priority patent/EP1534429A4/en
Priority to AU2003253944A priority patent/AU2003253944A1/en
Priority to CA002493700A priority patent/CA2493700A1/en
Publication of WO2004011365A2 publication Critical patent/WO2004011365A2/en
Publication of WO2004011365A3 publication Critical patent/WO2004011365A3/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0605Metering of fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0803Disc shape
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces

Abstract

Microfluidic device (100) is formed in substrate (108) and can include input port (106) in fluid communication with input channel (104) connected to feed channel (110). The microfluidic devices have a plurality of specialized processing features that facilitate centripetal fluid transfer is also provided.
PCT/US2003/022226 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer WO2004011365A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2005505600A JP2005533651A (en) 2002-07-26 2003-07-16 Microchannel design features that facilitate fluid movement by centripetal force
EP03771636A EP1534429A4 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer
AU2003253944A AU2003253944A1 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer
CA002493700A CA2493700A1 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US39885102P 2002-07-26 2002-07-26
US60/398,851 2002-07-26
US39954802P 2002-07-30 2002-07-30
US60/399,548 2002-07-30
US36633003A 2003-01-03 2003-01-03
US10/336,274 US7198759B2 (en) 2002-07-26 2003-01-03 Microfluidic devices, methods, and systems
US10/366,330 2003-01-03
US10/336,706 US7214348B2 (en) 2002-07-26 2003-01-03 Microfluidic size-exclusion devices, systems, and methods
US10/336,706 2003-01-03
US10/336,274 2003-01-03

Publications (2)

Publication Number Publication Date
WO2004011365A2 WO2004011365A2 (en) 2004-02-05
WO2004011365A3 true WO2004011365A3 (en) 2004-06-10

Family

ID=31192473

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/022226 WO2004011365A2 (en) 2002-07-26 2003-07-16 Micro-channel design features that facilitate centripetal fluid transfer

Country Status (5)

Country Link
EP (1) EP1534429A4 (en)
JP (1) JP2005533651A (en)
AU (1) AU2003253944A1 (en)
CA (1) CA2493700A1 (en)
WO (1) WO2004011365A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device
US9168523B2 (en) 2011-05-18 2015-10-27 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6720187B2 (en) 2000-06-28 2004-04-13 3M Innovative Properties Company Multi-format sample processing devices
US6627159B1 (en) 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
US6734401B2 (en) 2000-06-28 2004-05-11 3M Innovative Properties Company Enhanced sample processing devices, systems and methods
US7323660B2 (en) 2005-07-05 2008-01-29 3M Innovative Properties Company Modular sample processing apparatus kits and modules
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods
US7763210B2 (en) 2005-07-05 2010-07-27 3M Innovative Properties Company Compliant microfluidic sample processing disks
JP5131538B2 (en) * 2008-05-07 2013-01-30 セイコーエプソン株式会社 Reaction liquid filling method
JP5298718B2 (en) * 2008-09-12 2013-09-25 セイコーエプソン株式会社 Centrifugal device for filling biological sample reaction chip with reaction solution
CN101533005B (en) * 2009-04-14 2012-10-10 北京大学 Microflow distribution device, manufacturing method and application thereof
EP2709760B1 (en) 2011-05-18 2019-06-05 DiaSorin S.p.A. Systems and methods for valving on a sample processing device
JP2015031643A (en) * 2013-08-06 2015-02-16 ブラザー工業株式会社 Inspection chip

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020037499A1 (en) * 2000-06-05 2002-03-28 California Institute Of Technology Integrated active flux microfluidic devices and methods
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0791238B1 (en) * 1994-11-10 2004-09-22 Orchid BioSciences, Inc. Liquid distribution system
KR100306951B1 (en) * 1995-12-05 2001-11-15 테칸 보스턴, 인코포레이티드 Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
US20010055812A1 (en) * 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
EP1092144A1 (en) * 1998-06-29 2001-04-18 Evotec BioSystems AG Method and device for manipulating particles in microsystems
AU763497B2 (en) * 1998-10-13 2003-07-24 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
JP2002530770A (en) * 1998-11-20 2002-09-17 セピアテック ジーエムビーエイチ Method and apparatus for regulating individual partial flows of a delivery system for a flowing medium
GB9828785D0 (en) * 1998-12-30 1999-02-17 Amersham Pharm Biotech Ab Sequencing systems
US6395232B1 (en) * 1999-07-09 2002-05-28 Orchid Biosciences, Inc. Fluid delivery system for a microfluidic device using a pressure pulse
EP1284819A2 (en) * 2000-05-15 2003-02-26 Tecan Trading AG Microfluidics devices and methods for high throughput screening
US6627159B1 (en) * 2000-06-28 2003-09-30 3M Innovative Properties Company Centrifugal filling of sample processing devices
AU2002243148A1 (en) * 2001-03-19 2002-10-03 Gyros Ab Structural units that define fluidic functions
AU2002213115A1 (en) * 2001-04-13 2002-10-28 Nanostream, Inc. Microfluidic metering systems and methods
AU2003219829A1 (en) * 2002-02-23 2003-09-09 Nanostream, Inc. Microfluidic multi-splitter

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system
US20020037499A1 (en) * 2000-06-05 2002-03-28 California Institute Of Technology Integrated active flux microfluidic devices and methods

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
US8931331B2 (en) 2011-05-18 2015-01-13 3M Innovative Properties Company Systems and methods for volumetric metering on a sample processing device
US9168523B2 (en) 2011-05-18 2015-10-27 3M Innovative Properties Company Systems and methods for detecting the presence of a selected volume of material in a sample processing device

Also Published As

Publication number Publication date
JP2005533651A (en) 2005-11-10
EP1534429A2 (en) 2005-06-01
WO2004011365A2 (en) 2004-02-05
AU2003253944A1 (en) 2004-02-16
CA2493700A1 (en) 2004-02-05
EP1534429A4 (en) 2005-09-07

Similar Documents

Publication Publication Date Title
WO2004011365A3 (en) Micro-channel design features that facilitate centripetal fluid transfer
WO2003045559A3 (en) Microfluidic devices with distributing inputs
WO2004052540A3 (en) Configurable microfluidic substrate assembly
WO2003035229A3 (en) Integrated fluidic device for sample preparation and assay
WO2002081085A3 (en) Well-plate with microfluidic structures
WO2006102321A3 (en) Fluid processing device with captured reagent beads
WO2007024485A8 (en) Microfluidic reduction of diffusion and complience effect in a fluid mixing region
WO2005060560A3 (en) Suction sleeve and interventional devices having such a suction sleeve
AU2002326881A1 (en) Microfluidic device having a reduced number of input and output connections
WO2004105946A3 (en) Packaging of microfluidic devices
CA2261869A1 (en) Integrated microfluidic devices
WO2003035909A3 (en) A method for detecting disease using a fluidic device
WO2003084450A8 (en) Time or time-temperature indicating articles
WO2004098757A3 (en) Microfluidic mixing using flow pulsing
WO2007005853A3 (en) Compliant microfluidic sample processing disks
WO2003068670A3 (en) Microfluidic valve and system therefor
WO2004042357A3 (en) Thermal micro-valves for micro-integrated devices
WO2004045671A3 (en) Microstructure roller system
WO2007024417A3 (en) Fluid processing device, system, kit, and method
WO2004077258A3 (en) System and method for structuring distributed applications
EP1479943A4 (en) Speed change device
EP2281633A8 (en) Retaining microfluidic microcavity and other microfluidic structures
TW200622176A (en) Pulsating heat conveyance apparatus
WO2002044996A3 (en) Integrated circuit for conditioning and conversion of bi-directional discrete and analog signals
WO2004103886A3 (en) Microfabricated micro fluid channels

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2003771636

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2003253944

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2493700

Country of ref document: CA

Ref document number: 2005505600

Country of ref document: JP

WWP Wipo information: published in national office

Ref document number: 2003771636

Country of ref document: EP