WO2003087767A3 - A system and method for quantifying the dynamic response of a target system - Google Patents

A system and method for quantifying the dynamic response of a target system Download PDF

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Publication number
WO2003087767A3
WO2003087767A3 PCT/US2003/010785 US0310785W WO03087767A3 WO 2003087767 A3 WO2003087767 A3 WO 2003087767A3 US 0310785 W US0310785 W US 0310785W WO 03087767 A3 WO03087767 A3 WO 03087767A3
Authority
WO
WIPO (PCT)
Prior art keywords
human
tissue site
data
vasculature
target
Prior art date
Application number
PCT/US2003/010785
Other languages
French (fr)
Other versions
WO2003087767A2 (en
Inventor
Randall L Barbour
Original Assignee
Randall L Barbour
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Randall L Barbour filed Critical Randall L Barbour
Priority to JP2003584664A priority Critical patent/JP4472357B2/en
Priority to EP03746663A priority patent/EP1492453A4/en
Priority to CA002481518A priority patent/CA2481518A1/en
Priority to AU2003247336A priority patent/AU2003247336A1/en
Publication of WO2003087767A2 publication Critical patent/WO2003087767A2/en
Publication of WO2003087767A3 publication Critical patent/WO2003087767A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0091—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312—Breast evaluation or disorder diagnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4884—Other medical applications inducing physiological or psychological stress, e.g. applications for stress testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/726—Details of waveform analysis characterised by using transforms using Wavelet transforms

Abstract

A time series of optical tomography data is obtained for a target tissue site (116) in a human (or animal), using an optical wavelength, such as near infrared, at which hemoglobin is absorptive, to observe properties of the vasculature of the human. The data may be compared to baseline data of a corresponding tissue site, e.g., from a healthy human, or from another, corresponding tissue site of the human. For example, a suspected cancerous breast of a human may be compared to a known healthy breast to detect differences in the vasculature. Measures may be made of flow, oxygen supply/demand imbalance, and evidence of altered regulation of the peripheral effector mechanism. The function of the target tissue site may be analyzed, along with the coordinated interaction between multiple sites of the target system. A provocation may be administered to identify surrogate markers of an underlying state or process.
PCT/US2003/010785 2002-04-06 2003-04-07 A system and method for quantifying the dynamic response of a target system WO2003087767A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2003584664A JP4472357B2 (en) 2002-04-06 2003-04-07 System and method for quantifying the dynamic response of a target body
EP03746663A EP1492453A4 (en) 2002-04-06 2003-04-07 A system and method for quantifying the dynamic response of a target system
CA002481518A CA2481518A1 (en) 2002-04-06 2003-04-07 A system and method for quantifying the dynamic response of a target system
AU2003247336A AU2003247336A1 (en) 2002-04-06 2003-04-07 A system and method for quantifying the dynamic response of a target system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37030502P 2002-04-06 2002-04-06
US60/370,305 2002-04-06

Publications (2)

Publication Number Publication Date
WO2003087767A2 WO2003087767A2 (en) 2003-10-23
WO2003087767A3 true WO2003087767A3 (en) 2004-03-25

Family

ID=29250511

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/010785 WO2003087767A2 (en) 2002-04-06 2003-04-07 A system and method for quantifying the dynamic response of a target system

Country Status (6)

Country Link
US (1) US7778693B2 (en)
EP (1) EP1492453A4 (en)
JP (1) JP4472357B2 (en)
AU (1) AU2003247336A1 (en)
CA (1) CA2481518A1 (en)
WO (1) WO2003087767A2 (en)

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Also Published As

Publication number Publication date
JP2006505299A (en) 2006-02-16
US20040039268A1 (en) 2004-02-26
JP4472357B2 (en) 2010-06-02
US7778693B2 (en) 2010-08-17
EP1492453A2 (en) 2005-01-05
WO2003087767A2 (en) 2003-10-23
EP1492453A4 (en) 2009-03-04
AU2003247336A1 (en) 2003-10-27
CA2481518A1 (en) 2003-10-23

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