WO2003040024A3 - Assay basierend auf dotierten nanoteilchen - Google Patents
Assay basierend auf dotierten nanoteilchen Download PDFInfo
- Publication number
- WO2003040024A3 WO2003040024A3 PCT/EP2002/012256 EP0212256W WO03040024A3 WO 2003040024 A3 WO2003040024 A3 WO 2003040024A3 EP 0212256 W EP0212256 W EP 0212256W WO 03040024 A3 WO03040024 A3 WO 03040024A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- donor
- molecule
- acceptor
- assay based
- energy
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2465646A CA2465646C (en) | 2001-11-05 | 2002-11-04 | Assay based on doped nanoparticles |
EP02787546A EP1444517B1 (de) | 2001-11-05 | 2002-11-04 | Assay basierend auf dotierten nanoteilchen |
US10/494,390 US7410810B2 (en) | 2001-11-05 | 2002-11-04 | Assay based on doped nanoparticles |
JP2003542078A JP4233452B2 (ja) | 2001-11-05 | 2002-11-04 | ドープしたナノ粒子に基づくアッセイ |
DE50210393T DE50210393D1 (de) | 2001-11-05 | 2002-11-04 | Assay basierend auf dotierten nanoteilchen |
AU2002351820A AU2002351820B2 (en) | 2001-11-05 | 2002-11-04 | Assay based on doped nanoparticles |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10153829A DE10153829A1 (de) | 2001-11-05 | 2001-11-05 | Assay basierend auf dotierten Nanoteilchen |
DE10153829.4 | 2001-11-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003040024A2 WO2003040024A2 (de) | 2003-05-15 |
WO2003040024A3 true WO2003040024A3 (de) | 2003-10-23 |
Family
ID=7704386
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2002/012256 WO2003040024A2 (de) | 2001-11-05 | 2002-11-04 | Assay basierend auf dotierten nanoteilchen |
Country Status (9)
Country | Link |
---|---|
US (1) | US7410810B2 (de) |
EP (1) | EP1444517B1 (de) |
JP (1) | JP4233452B2 (de) |
AT (1) | ATE365917T1 (de) |
AU (1) | AU2002351820B2 (de) |
CA (1) | CA2465646C (de) |
DE (2) | DE10153829A1 (de) |
ES (1) | ES2287342T3 (de) |
WO (1) | WO2003040024A2 (de) |
Families Citing this family (52)
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DE10221792A1 (de) * | 2002-05-15 | 2003-11-27 | Caesar Stiftung | Elasto-Optischer Biosensor |
US10001475B2 (en) | 2002-06-20 | 2018-06-19 | The Regents Of The University Of California | Light harvesting multichromophore compositions and methods of using the same |
US7144950B2 (en) | 2003-09-17 | 2006-12-05 | The Regents Of The University Of California | Conformationally flexible cationic conjugated polymers |
US9371559B2 (en) | 2002-06-20 | 2016-06-21 | The Regents Of The University Of California | Compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
EA007653B1 (ru) | 2002-08-26 | 2006-12-29 | Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния | Способы и композиции обнаружения и анализа полинуклеотидов с помощью светособирающих полихромофоров |
JP2004196649A (ja) * | 2002-12-06 | 2004-07-15 | Sumitomo Electric Ind Ltd | 蛍光性ガラス、光増幅用導波路および光増幅モジュール |
DK1599609T3 (da) * | 2003-02-13 | 2010-03-29 | Univ California | Fremgangsmåder og sammensætninger til detektering og analyse af polynukleotid-bindende proteins vekselvirkninger ved brug af lys samlende multichromophorer |
ATE346898T1 (de) | 2003-04-30 | 2006-12-15 | Nanosolutions Gmbh | Kern-mantel nanoteilchen für (f) ret- testverfahren |
US20080076119A9 (en) * | 2003-12-29 | 2008-03-27 | Lei Sun | Composite organic inorganic nanoclusters |
US7361410B2 (en) * | 2003-12-29 | 2008-04-22 | Intel Corporation | External modification of composite organic inorganic nanoclusters comprising raman active organic compound |
US20050147963A1 (en) * | 2003-12-29 | 2005-07-07 | Intel Corporation | Composite organic-inorganic nanoparticles and methods for use thereof |
US20050191665A1 (en) * | 2003-12-29 | 2005-09-01 | Xing Su | Composite organic-inorganic nanoclusters |
US20070166543A1 (en) | 2004-01-29 | 2007-07-19 | Keio University | Metal oxide phosphor microparticle and process for producing the same; utilizing the same, dispersion liquid, fluorescence conversion membrane, method of separating metal oxide phosphor microparticle, fluorescent liquid, fluorescent paste, phosphor and process for producing the same; and fluorescence converter |
JP2005320468A (ja) * | 2004-05-11 | 2005-11-17 | Fuji Photo Film Co Ltd | ナノ粒子蛍光体及びその分散液 |
US20080020483A1 (en) * | 2004-07-16 | 2008-01-24 | Junji Nishigaki | Fluorescence Detecting Method |
US20070048797A1 (en) * | 2004-08-11 | 2007-03-01 | Xing Su | Composite organic inorganic nanoclusters as carriers and identifiers of tester molecules |
US7776547B2 (en) * | 2004-08-26 | 2010-08-17 | Intel Corporation | Cellular analysis using Raman surface scanning |
US7368086B2 (en) * | 2004-10-29 | 2008-05-06 | Invitrogen Corporation | Functionalized fluorescent nanocrystals, and methods for their preparation and use |
US20060147941A1 (en) * | 2004-12-30 | 2006-07-06 | Intel Corporation | Methods and apparatus for SERS assay of biological analytes |
EP1838752B1 (de) | 2005-01-10 | 2017-10-04 | The Regents of The University of California | Kationische konjugierte polymere zur strangspezifischen polynukleotid-erkennung in homogenen festkörper-testanordnungen |
US7811755B2 (en) * | 2005-01-10 | 2010-10-12 | The Regents Of The University Of California | Methods and articles for strand-specific polynucleotide detection with cationic multichromophores |
US8097742B2 (en) * | 2005-01-20 | 2012-01-17 | Agency For Science, Technology And Research | Water-soluble, surface-functionalized nanoparticle for bioconjugation via universal silane coupling |
US7666594B2 (en) * | 2005-01-31 | 2010-02-23 | The Regents Of The University Of California | Methods for assaying a sample for an aggregant |
EP1866901B1 (de) * | 2005-04-01 | 2012-05-16 | Prysm, Inc. | Anzeigesysteme und -einrichtungen mit bildschirmen mit optisch fluoreszierenden materialien |
DE102005026485A1 (de) * | 2005-06-09 | 2006-12-14 | Bayer Technology Services Gmbh | Hydrophile Nanoteilchen mit funktionellen Oberflächengruppen, deren Herstellung und Verwendung |
US7410763B2 (en) * | 2005-09-01 | 2008-08-12 | Intel Corporation | Multiplex data collection and analysis in bioanalyte detection |
DE102005044071A1 (de) * | 2005-09-07 | 2007-03-08 | Nimbus Biotechnologie Gmbh | Verfahren zur Messung der Permeation einer Substanz durch eine Barriere |
US20090098057A1 (en) * | 2007-10-16 | 2009-04-16 | Shiying Zheng | Silica-cored carrier particle |
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US20070155022A1 (en) * | 2005-12-30 | 2007-07-05 | Mineo Yamakawa | Degenerate binding detection and protein identification using Raman spectroscopy nanoparticle labels |
US8198099B2 (en) | 2006-07-07 | 2012-06-12 | The University Of Miami | Mechanism to signal receptor-ligand interactions with luminescent quantum dots |
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US8297061B2 (en) * | 2007-08-02 | 2012-10-30 | Cree, Inc. | Optoelectronic device with upconverting luminophoric medium |
JP5124216B2 (ja) * | 2007-09-14 | 2013-01-23 | オリンパス株式会社 | 光シグナル観察方法および光シグナル観察システム |
US8951731B2 (en) * | 2007-10-15 | 2015-02-10 | Complete Genomics, Inc. | Sequence analysis using decorated nucleic acids |
CN102119119B (zh) * | 2008-06-27 | 2015-06-17 | 叶夫根尼·彼得罗维奇·格列比翁尼科夫 | 纳米复合材料 |
KR101834574B1 (ko) | 2009-01-29 | 2018-03-05 | 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 | G 단백질 커플링 수용체 활성화 측정 |
JP5717951B2 (ja) * | 2009-03-23 | 2015-05-13 | オリンパス株式会社 | 発光観察システム |
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US9459212B2 (en) * | 2009-12-17 | 2016-10-04 | University Of Maryland, Baltimore County | Mixed-metal substrates for metal-enhanced fluorescence |
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DE102014203266B4 (de) | 2014-02-24 | 2018-07-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Zusammensetzung mit FRET-Paar in definierter Geometrie |
US10421127B2 (en) * | 2014-09-03 | 2019-09-24 | Raytheon Company | Method for forming lanthanide nanoparticles |
EP2998737B1 (de) * | 2014-09-18 | 2021-04-21 | Nokia Technologies Oy | Vorrichtung und Verfahren zur steuerbaren Bestückung eines Kanals mit Ladungsträger, unter Benutzung von an dem Kanal befestigten Quantenpunkten und "Resonance Energy Transfer". |
WO2017127759A1 (en) | 2016-01-22 | 2017-07-27 | The Regents Of The University Of California | Formation and use of embedded solutions in nanoscale materials |
WO2018183341A1 (en) | 2017-03-27 | 2018-10-04 | Firouzeh Sabri | Light weight flexible temperature sensor kit |
KR102098030B1 (ko) * | 2017-12-11 | 2020-04-07 | 주식회사 딕스젠 | 결핵진단용 조성물 및 광학적 특성 변화에 기반한 결핵 진단방법 |
CN110280755B (zh) * | 2019-07-12 | 2020-02-18 | 北京市疾病预防控制中心 | 一种用于检测过氧化苯甲酰的金纳米探针及其制备方法和用途 |
US20210324458A1 (en) * | 2020-04-15 | 2021-10-21 | Nanopec, Inc. | Enhanced signal to noise ratios for pcr testing within a fret doped nano-structured ceramic film |
CN116465872B (zh) * | 2023-05-09 | 2023-11-28 | 临沂大学 | 一种快速检测微囊藻毒素方法 |
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WO1998043072A1 (en) * | 1997-03-25 | 1998-10-01 | Photonic Research Systems Limited | Luminescence assays |
US5893999A (en) * | 1993-09-13 | 1999-04-13 | Kabushiki Kaisha Toshiba | Ultrafine inorganic phosphor, specifically binding material labeled with this phosphor, and detection method using this specific binding material |
US6159686A (en) * | 1992-09-14 | 2000-12-12 | Sri International | Up-converting reporters for biological and other assays |
US6207392B1 (en) * | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
WO2002044725A1 (en) * | 2000-11-30 | 2002-06-06 | Innotrac Diagnostics Oy | Bioanalytical assay |
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- 2001-11-05 DE DE10153829A patent/DE10153829A1/de not_active Ceased
-
2002
- 2002-11-04 AU AU2002351820A patent/AU2002351820B2/en not_active Ceased
- 2002-11-04 ES ES02787546T patent/ES2287342T3/es not_active Expired - Lifetime
- 2002-11-04 AT AT02787546T patent/ATE365917T1/de not_active IP Right Cessation
- 2002-11-04 EP EP02787546A patent/EP1444517B1/de not_active Expired - Lifetime
- 2002-11-04 WO PCT/EP2002/012256 patent/WO2003040024A2/de active IP Right Grant
- 2002-11-04 CA CA2465646A patent/CA2465646C/en not_active Expired - Fee Related
- 2002-11-04 US US10/494,390 patent/US7410810B2/en not_active Expired - Fee Related
- 2002-11-04 DE DE50210393T patent/DE50210393D1/de not_active Expired - Lifetime
- 2002-11-04 JP JP2003542078A patent/JP4233452B2/ja not_active Expired - Fee Related
Patent Citations (5)
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US6159686A (en) * | 1992-09-14 | 2000-12-12 | Sri International | Up-converting reporters for biological and other assays |
US5893999A (en) * | 1993-09-13 | 1999-04-13 | Kabushiki Kaisha Toshiba | Ultrafine inorganic phosphor, specifically binding material labeled with this phosphor, and detection method using this specific binding material |
WO1998043072A1 (en) * | 1997-03-25 | 1998-10-01 | Photonic Research Systems Limited | Luminescence assays |
US6207392B1 (en) * | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
WO2002044725A1 (en) * | 2000-11-30 | 2002-06-06 | Innotrac Diagnostics Oy | Bioanalytical assay |
Also Published As
Publication number | Publication date |
---|---|
AU2002351820B2 (en) | 2007-11-29 |
CA2465646C (en) | 2012-04-17 |
DE10153829A1 (de) | 2003-05-28 |
US7410810B2 (en) | 2008-08-12 |
US20050064604A1 (en) | 2005-03-24 |
EP1444517A2 (de) | 2004-08-11 |
CA2465646A1 (en) | 2003-05-15 |
DE50210393D1 (de) | 2007-08-09 |
ATE365917T1 (de) | 2007-07-15 |
JP4233452B2 (ja) | 2009-03-04 |
WO2003040024A2 (de) | 2003-05-15 |
JP2005508012A (ja) | 2005-03-24 |
EP1444517B1 (de) | 2007-06-27 |
ES2287342T3 (es) | 2007-12-16 |
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