WO2002074194A3 - Stent with medicated multi-layer hydrid polymer coating - Google Patents

Stent with medicated multi-layer hydrid polymer coating Download PDF

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Publication number
WO2002074194A3
WO2002074194A3 PCT/US2002/008039 US0208039W WO02074194A3 WO 2002074194 A3 WO2002074194 A3 WO 2002074194A3 US 0208039 W US0208039 W US 0208039W WO 02074194 A3 WO02074194 A3 WO 02074194A3
Authority
WO
WIPO (PCT)
Prior art keywords
hydrid
layer
stent
polymer coating
medicated
Prior art date
Application number
PCT/US2002/008039
Other languages
French (fr)
Other versions
WO2002074194A2 (en
Inventor
Richard J Whitbourne
Alexandra M Chamberlain
Daniel G Hullihen
Scott F Rosebrough
Mildred Calistri-Yeh
Original Assignee
Sts Biopolymers Inc
Richard J Whitbourne
Alexandra M Chamberlain
Daniel G Hullihen
Scott F Rosebrough
Mildred Calistri-Yeh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sts Biopolymers Inc, Richard J Whitbourne, Alexandra M Chamberlain, Daniel G Hullihen, Scott F Rosebrough, Mildred Calistri-Yeh filed Critical Sts Biopolymers Inc
Priority to EP02721439A priority Critical patent/EP1399094A4/en
Priority to AU2002252372A priority patent/AU2002252372A1/en
Priority to JP2002572908A priority patent/JP2004526499A/en
Publication of WO2002074194A2 publication Critical patent/WO2002074194A2/en
Priority to US10/662,877 priority patent/US7771468B2/en
Publication of WO2002074194A3 publication Critical patent/WO2002074194A3/en
Priority to US12/828,512 priority patent/US8287590B2/en
Priority to US13/651,828 priority patent/US20130253636A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body

Abstract

Stents have medicated multi-layer hydrid polymer coatings for treating stenosis vasculature or other body passaged. Cumulative quantities of paclitaxel eluted, in micrograms over a period of hours and days (Figure 1).
PCT/US2002/008039 2001-03-16 2002-03-18 Stent with medicated multi-layer hydrid polymer coating WO2002074194A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP02721439A EP1399094A4 (en) 2001-03-16 2002-03-18 Medicated stent having multi-layer polymer coating
AU2002252372A AU2002252372A1 (en) 2001-03-16 2002-03-18 Stent with medicated multi-layer hydrid polymer coating
JP2002572908A JP2004526499A (en) 2001-03-16 2002-03-18 Drug-loaded stent with multi-layer polymer coating
US10/662,877 US7771468B2 (en) 2001-03-16 2003-09-16 Medicated stent having multi-layer polymer coating
US12/828,512 US8287590B2 (en) 2001-03-16 2010-07-01 Medicated stent having multi-layer polymer coating
US13/651,828 US20130253636A1 (en) 2001-03-16 2012-10-15 Medicated stent having multi-layer polymer coating

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27608901P 2001-03-16 2001-03-16
US60/276,089 2001-03-16

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US27608901P Continuation 2001-03-16 2001-03-16

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10/662,877 Continuation-In-Part US7771468B2 (en) 2001-03-16 2003-09-16 Medicated stent having multi-layer polymer coating
US12/828,512 Continuation-In-Part US8287590B2 (en) 2001-03-16 2010-07-01 Medicated stent having multi-layer polymer coating

Publications (2)

Publication Number Publication Date
WO2002074194A2 WO2002074194A2 (en) 2002-09-26
WO2002074194A3 true WO2002074194A3 (en) 2004-01-08

Family

ID=23055120

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/008039 WO2002074194A2 (en) 2001-03-16 2002-03-18 Stent with medicated multi-layer hydrid polymer coating

Country Status (4)

Country Link
EP (1) EP1399094A4 (en)
JP (2) JP2004526499A (en)
AU (1) AU2002252372A1 (en)
WO (1) WO2002074194A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE45744E1 (en) 2003-12-01 2015-10-13 Abbott Cardiovascular Systems Inc. Temperature controlled crimping

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US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6908624B2 (en) * 1999-12-23 2005-06-21 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US7771468B2 (en) * 2001-03-16 2010-08-10 Angiotech Biocoatings Corp. Medicated stent having multi-layer polymer coating
KR100455343B1 (en) * 2001-08-29 2004-11-12 학교법인 인하학원 Covering composition for drug releasing stent and drug releasing stent manufactured using same
US8003179B2 (en) * 2002-06-20 2011-08-23 Alcan Packaging Flexible France Films having a desiccant material incorporated therein and methods of use and manufacture
EP1569762B1 (en) * 2002-10-22 2007-10-03 Medtronic Vascular, Inc. Stent with intermittent coating
SI2656854T1 (en) * 2003-02-04 2015-09-30 Cornell Research Foundation, Inc. Uses of aromatic-cationic peptide
US7318945B2 (en) 2003-07-09 2008-01-15 Medtronic Vascular, Inc. Laminated drug-polymer coated stent having dipped layers
US20050064005A1 (en) * 2003-08-13 2005-03-24 Dinh Thomas Q. Active agent delivery systems including a miscible polymer blend, medical devices, and methods
WO2005018697A2 (en) * 2003-08-13 2005-03-03 Medtronic, Inc. Active agent delivery systems, including a single layer of a miscible polymer blend, medical devices, and methods
DE602004018509D1 (en) * 2003-08-19 2009-01-29 Polybiomed Ltd POLYMERIC MEDICINAL SPREADING SYSTEM FOR MEDICAL DEVICES
JP2006198078A (en) * 2005-01-19 2006-08-03 Terumo Corp Stent
WO2007011708A2 (en) 2005-07-15 2007-01-25 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
PL1909973T3 (en) 2005-07-15 2019-01-31 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
US8852625B2 (en) 2006-04-26 2014-10-07 Micell Technologies, Inc. Coatings containing multiple drugs
CN102886326A (en) 2006-10-23 2013-01-23 米歇尔技术公司 Holder for electrically charging a substrate during coating
WO2008070996A1 (en) * 2006-12-13 2008-06-19 Angiotech Pharmaceuticals Inc. Medical implants with a combination of compounds
EP1942128B1 (en) 2006-12-29 2016-09-14 Abbott Laboratories Vascular Enterprises Limited Modified polyamides
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
US9737642B2 (en) 2007-01-08 2017-08-22 Micell Technologies, Inc. Stents having biodegradable layers
EP1990356A1 (en) 2007-05-10 2008-11-12 Abbott Laboratories Vascular Enterprises Limited Co-polymer of a modifed polyamide and a polycarbonate
EP1990357A1 (en) * 2007-05-10 2008-11-12 Abbott Laboratories Vascular Enterprises Limited Co-polymer of a polyamide and a polycarbonate diamine
WO2009031295A1 (en) 2007-09-04 2009-03-12 Japan Stent Technology Co., Ltd. Stent for controlled drug release
AU2009251504B2 (en) 2008-04-17 2013-09-05 Micell Technologies, Inc. Stents having bioabsorbable layers
JP2011528275A (en) 2008-07-17 2011-11-17 ミセル テクノロジーズ，インク． Drug delivery medical device
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
WO2010101072A1 (en) * 2009-03-02 2010-09-10 株式会社日本ステントテクノロジー Drug releasing stent
CN102481195B (en) 2009-04-01 2015-03-25 米歇尔技术公司 Drug delivery medical device
EP2419058B1 (en) 2009-04-17 2018-02-28 Micell Technologies, Inc. Stents having controlled elution
EP2531140B1 (en) 2010-02-02 2017-11-01 Micell Technologies, Inc. Stent and stent delivery system with improved deliverability
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
WO2011133655A1 (en) 2010-04-22 2011-10-27 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
CA2805631C (en) 2010-07-16 2018-07-31 Micell Technologies, Inc. Drug delivery medical device
CN102166377A (en) * 2011-01-05 2011-08-31 北京泰杰伟业科技有限公司 Composition, preparation method and use method of lubricating hydrophilic coating for medical catheter
US10464100B2 (en) 2011-05-31 2019-11-05 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
US10117972B2 (en) 2011-07-15 2018-11-06 Micell Technologies, Inc. Drug delivery medical device
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
JP6330024B2 (en) 2013-03-12 2018-05-23 マイセル・テクノロジーズ，インコーポレイテッド Bioabsorbable biomedical implant
US9320592B2 (en) * 2013-03-15 2016-04-26 Covidien Lp Coated medical devices and methods of making and using same
US9545301B2 (en) 2013-03-15 2017-01-17 Covidien Lp Coated medical devices and methods of making and using same
CN105377318A (en) 2013-05-15 2016-03-02 脉胜医疗技术公司 Bioabsorbable biomedical implants
US9668890B2 (en) 2013-11-22 2017-06-06 Covidien Lp Anti-thrombogenic medical devices and methods
CN109966548A (en) * 2019-03-05 2019-07-05 太阳雨林（厦门）生物医药有限公司 A kind of bilayer polymer Material cladding blood vessel

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US5873904A (en) * 1995-06-07 1999-02-23 Cook Incorporated Silver implantable medical device
US6251136B1 (en) * 1999-12-08 2001-06-26 Advanced Cardiovascular Systems, Inc. Method of layering a three-coated stent using pharmacological and polymeric agents

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US4800882A (en) 1987-03-13 1989-01-31 Cook Incorporated Endovascular stent and delivery system
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US5962620A (en) * 1996-08-26 1999-10-05 Tyndale Plains-Hunter, Ltd. Hydrophicic and hydrophobic polyether polyurethanes and uses therefor
JP2000513988A (en) * 1997-06-18 2000-10-24 ボストン サイエンティフィック リミテッド Polycarbonate-polyurethane dispersion for antithrombotic coating
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US6379382B1 (en) * 2000-03-13 2002-04-30 Jun Yang Stent having cover with drug delivery capability

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Publication number Priority date Publication date Assignee Title
US5609629A (en) * 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US5873904A (en) * 1995-06-07 1999-02-23 Cook Incorporated Silver implantable medical device
US6251136B1 (en) * 1999-12-08 2001-06-26 Advanced Cardiovascular Systems, Inc. Method of layering a three-coated stent using pharmacological and polymeric agents

Non-Patent Citations (1)

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See also references of EP1399094A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE45744E1 (en) 2003-12-01 2015-10-13 Abbott Cardiovascular Systems Inc. Temperature controlled crimping

Also Published As

Publication number Publication date
WO2002074194A2 (en) 2002-09-26
EP1399094A4 (en) 2004-07-28
JP2004526499A (en) 2004-09-02
EP1399094A2 (en) 2004-03-24
JP2009160427A (en) 2009-07-23
AU2002252372A1 (en) 2002-10-03

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