WO2002074161A3 - Subcutaneous analyte sensor - Google Patents

Subcutaneous analyte sensor Download PDF

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Publication number
WO2002074161A3
WO2002074161A3 PCT/EP2002/002960 EP0202960W WO02074161A3 WO 2002074161 A3 WO2002074161 A3 WO 2002074161A3 EP 0202960 W EP0202960 W EP 0202960W WO 02074161 A3 WO02074161 A3 WO 02074161A3
Authority
WO
WIPO (PCT)
Prior art keywords
light
membrane
cavity
analyte
permeable
Prior art date
Application number
PCT/EP2002/002960
Other languages
French (fr)
Other versions
WO2002074161A2 (en
Inventor
Matthias Essenpreis
Martin Gerber
Wolfgang Petrich
Original Assignee
Roche Diagnostics Gmbh
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics Gmbh, Hoffmann La Roche filed Critical Roche Diagnostics Gmbh
Priority to JP2002572876A priority Critical patent/JP3692116B2/en
Priority to EP02703638A priority patent/EP1372466A2/en
Priority to AU2002237332A priority patent/AU2002237332A1/en
Priority to CA 2440854 priority patent/CA2440854C/en
Publication of WO2002074161A2 publication Critical patent/WO2002074161A2/en
Publication of WO2002074161A3 publication Critical patent/WO2002074161A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Assembly and method for measuring the concentration of an analyte in a biological matrix. The assembly includes an implantatble optical-sensing element (100) that comprises a body (104), and a membrane (110) mounted on the body in a manner such that the membrane and the body define a cavity. The membrane is permeable to the analyte, but is permeable to background species in the biological matrix. A refractive element (115) is positioned in the cavity. A light source (106) transmits light of a first intensity onto the refractive element, and a light detector (106) receives light of a second intensity that is reflected from the cavity. A controller device optically coupled to the detector compares the first and second light intensities, and relates the intensities to analyte concentration.
PCT/EP2002/002960 2001-03-16 2002-03-18 Subcutaneous analyte sensor WO2002074161A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2002572876A JP3692116B2 (en) 2001-03-16 2002-03-18 Subcutaneous specimen sensor
EP02703638A EP1372466A2 (en) 2001-03-16 2002-03-18 Subcutaneous analyte sensor
AU2002237332A AU2002237332A1 (en) 2001-03-16 2002-03-18 Subcutaneous analyte sensor
CA 2440854 CA2440854C (en) 2001-03-16 2002-03-18 Subcutaneous analyte sensor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/810,635 US6952603B2 (en) 2001-03-16 2001-03-16 Subcutaneous analyte sensor
US09/810,635 2001-03-16

Publications (2)

Publication Number Publication Date
WO2002074161A2 WO2002074161A2 (en) 2002-09-26
WO2002074161A3 true WO2002074161A3 (en) 2003-07-24

Family

ID=25204303

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/002960 WO2002074161A2 (en) 2001-03-16 2002-03-18 Subcutaneous analyte sensor

Country Status (6)

Country Link
US (3) US6952603B2 (en)
EP (1) EP1372466A2 (en)
JP (1) JP3692116B2 (en)
AU (1) AU2002237332A1 (en)
CA (1) CA2440854C (en)
WO (1) WO2002074161A2 (en)

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