WO2002030969A3 - Regulation of human carboxylesterase-like enzyme - Google Patents

Regulation of human carboxylesterase-like enzyme Download PDF

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Publication number
WO2002030969A3
WO2002030969A3 PCT/EP2001/011758 EP0111758W WO0230969A3 WO 2002030969 A3 WO2002030969 A3 WO 2002030969A3 EP 0111758 W EP0111758 W EP 0111758W WO 0230969 A3 WO0230969 A3 WO 0230969A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
human carboxylesterase
regulation
reagents
carboxylesterase
Prior art date
Application number
PCT/EP2001/011758
Other languages
French (fr)
Other versions
WO2002030969A2 (en
Inventor
Zhimin Zhu
Original Assignee
Bayer Ag
Zhimin Zhu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Zhimin Zhu filed Critical Bayer Ag
Priority to AU2002215942A priority Critical patent/AU2002215942A1/en
Publication of WO2002030969A2 publication Critical patent/WO2002030969A2/en
Publication of WO2002030969A3 publication Critical patent/WO2002030969A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

Reagents which regulate human carboxylesterase-like enzyme and reagents which bind to human carboxylesterase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, diseases due to organophosphorus intoxication, cancer, and COPD.
PCT/EP2001/011758 2000-10-13 2001-10-11 Regulation of human carboxylesterase-like enzyme WO2002030969A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002215942A AU2002215942A1 (en) 2000-10-13 2001-10-11 Regulation of human carboxylesterase-like enzyme

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23989800P 2000-10-13 2000-10-13
US60/239,898 2000-10-13
US31594701P 2001-08-31 2001-08-31
US60/315,947 2001-08-31

Publications (2)

Publication Number Publication Date
WO2002030969A2 WO2002030969A2 (en) 2002-04-18
WO2002030969A3 true WO2002030969A3 (en) 2002-09-12

Family

ID=26932976

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011758 WO2002030969A2 (en) 2000-10-13 2001-10-11 Regulation of human carboxylesterase-like enzyme

Country Status (2)

Country Link
AU (1) AU2002215942A1 (en)
WO (1) WO2002030969A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009029321A2 (en) * 2007-06-08 2009-03-05 Musc Foundation For Research Development Carboxylesterase-1 polymorphisms and methods of use therefor
CN114717216A (en) * 2022-03-31 2022-07-08 石河子大学 Gossypol degrading enzyme CCE001a gene, amino acid sequence and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001625A (en) * 1995-05-19 1999-12-14 The United States Of America As Represented By The Secretary Of The Army Site-directed mutagenesis of esterases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001625A (en) * 1995-05-19 1999-12-14 The United States Of America As Represented By The Secretary Of The Army Site-directed mutagenesis of esterases

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI, Hinxton, UK; 15 December 1992 (1992-12-15), KROETZ ET AL.: "Human carboxylesterase mRNA, complete cds.", XP002198156, Database accession no. L07765 *
DATABASE EMBL [online] EBI, Hinxton, UK; 31 July 1991 (1991-07-31), ZSCHUNKE ET AL.: "Human mRNA for monocyte/macrophage serine-esterase 1, partial", XP002198157, Database accession no. X52973 *
DATABASE EMBL [online] EBI, Hinxton, UK; 7 September 1999 (1999-09-07), ISLAM ET AL.: "Homo sapiens egasyn mRNA, complete cds.", XP002198158, Database accession no. AF177775 *

Also Published As

Publication number Publication date
AU2002215942A1 (en) 2002-04-22
WO2002030969A2 (en) 2002-04-18

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