WO2002017831A3 - Devices for intraocular drug delivery - Google Patents

Devices for intraocular drug delivery Download PDF

Info

Publication number
WO2002017831A3
WO2002017831A3 PCT/US2001/020119 US0120119W WO0217831A3 WO 2002017831 A3 WO2002017831 A3 WO 2002017831A3 US 0120119 W US0120119 W US 0120119W WO 0217831 A3 WO0217831 A3 WO 0217831A3
Authority
WO
WIPO (PCT)
Prior art keywords
delivery
devices
drug delivery
substances
therapeutic agent
Prior art date
Application number
PCT/US2001/020119
Other languages
French (fr)
Other versions
WO2002017831A2 (en
Inventor
Signe Varner
Eugene Dejuan Jr
Terry Shelly
Aaron Barnes
Mark Humayun
Original Assignee
Univ Johns Hopkins
Signe Varner
Eugene Dejuan Jr
Terry Shelly
Aaron Barnes
Mark Humayun
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins, Signe Varner, Eugene Dejuan Jr, Terry Shelly, Aaron Barnes, Mark Humayun filed Critical Univ Johns Hopkins
Priority to CA2420038A priority Critical patent/CA2420038C/en
Priority to DE60135352T priority patent/DE60135352D1/en
Priority to JP2002522807A priority patent/JP4471568B2/en
Priority to DK01950424T priority patent/DK1313415T3/en
Priority to AU7141701A priority patent/AU7141701A/en
Priority to EP01950424A priority patent/EP1313415B1/en
Priority to AU2001271417A priority patent/AU2001271417B2/en
Publication of WO2002017831A2 publication Critical patent/WO2002017831A2/en
Publication of WO2002017831A3 publication Critical patent/WO2002017831A3/en
Priority to AU2007200057A priority patent/AU2007200057B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00867Material properties shape memory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Prostheses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

A therapeutic agent delivery device that can allows is particularly suitable for delivery of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. Preferred devices of the invention are minimally invasive, refillable and may be easily fixed to the treatment area. Preferred delivery devices of the invention also include those that comprise a non-linear shaped body member housing one or more substances and a delivery mechanism for the sustained delivery of the one or more substances from the non-linear shaped body member to the patient.
PCT/US2001/020119 2000-08-30 2001-06-22 Devices for intraocular drug delivery WO2002017831A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CA2420038A CA2420038C (en) 2000-08-30 2001-06-22 Devices for intraocular drug delivery
DE60135352T DE60135352D1 (en) 2000-08-30 2001-06-22 DEVICE FOR INTRA-OCCULAR ACTIVE AGGREGATION
JP2002522807A JP4471568B2 (en) 2000-08-30 2001-06-22 Intraocular drug delivery device
DK01950424T DK1313415T3 (en) 2000-08-30 2001-06-22 Devices for intraocular drug administration
AU7141701A AU7141701A (en) 2000-08-30 2001-06-22 Devices for intraocular drug delivery
EP01950424A EP1313415B1 (en) 2000-08-30 2001-06-22 Devices for intraocular drug delivery
AU2001271417A AU2001271417B2 (en) 2000-08-30 2001-06-22 Devices for intraocular drug delivery
AU2007200057A AU2007200057B2 (en) 2000-08-30 2007-01-05 Devices for intraocular drug delivery

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22893400P 2000-08-30 2000-08-30
US60/228,934 2000-08-30

Publications (2)

Publication Number Publication Date
WO2002017831A2 WO2002017831A2 (en) 2002-03-07
WO2002017831A3 true WO2002017831A3 (en) 2002-07-11

Family

ID=22859147

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/020119 WO2002017831A2 (en) 2000-08-30 2001-06-22 Devices for intraocular drug delivery

Country Status (11)

Country Link
US (3) US6719750B2 (en)
EP (2) EP1313415B1 (en)
JP (1) JP4471568B2 (en)
AT (2) ATE547080T1 (en)
AU (3) AU2001271417B2 (en)
CA (1) CA2420038C (en)
DE (1) DE60135352D1 (en)
DK (1) DK1313415T3 (en)
ES (1) ES2312456T3 (en)
PT (1) PT1313415E (en)
WO (1) WO2002017831A2 (en)

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EP1313415B1 (en) 2008-08-13

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