WO2002000720A3 - Novel human gaba receptors and polynucleotides encoding the same - Google Patents

Novel human gaba receptors and polynucleotides encoding the same Download PDF

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Publication number
WO2002000720A3
WO2002000720A3 PCT/US2001/020417 US0120417W WO0200720A3 WO 2002000720 A3 WO2002000720 A3 WO 2002000720A3 US 0120417 W US0120417 W US 0120417W WO 0200720 A3 WO0200720 A3 WO 0200720A3
Authority
WO
WIPO (PCT)
Prior art keywords
same
novel human
polynucleotides encoding
gaba receptors
human gaba
Prior art date
Application number
PCT/US2001/020417
Other languages
French (fr)
Other versions
WO2002000720A2 (en
Inventor
D Wade Walke
Carl Johan Friddle
Brian Mathur
C Alexander Turner Jr
Original Assignee
Lexicon Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexicon Genetics Inc filed Critical Lexicon Genetics Inc
Priority to AU2001271516A priority Critical patent/AU2001271516B2/en
Priority to AU7151601A priority patent/AU7151601A/en
Priority to CA002415761A priority patent/CA2415761A1/en
Priority to JP2002505842A priority patent/JP2004510412A/en
Priority to EP01950535A priority patent/EP1297134A2/en
Publication of WO2002000720A2 publication Critical patent/WO2002000720A2/en
Publication of WO2002000720A3 publication Critical patent/WO2002000720A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
PCT/US2001/020417 2000-06-27 2001-06-27 Novel human gaba receptors and polynucleotides encoding the same WO2002000720A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2001271516A AU2001271516B2 (en) 2000-06-27 2001-06-27 Novel human gaba receptors and polynucleotides encoding the same
AU7151601A AU7151601A (en) 2000-06-27 2001-06-27 Novel human gaba receptors and polynucleotides encoding the same
CA002415761A CA2415761A1 (en) 2000-06-27 2001-06-27 Novel human gaba receptors and polynucleotides encoding the same
JP2002505842A JP2004510412A (en) 2000-06-27 2001-06-27 Novel human GABA receptor and polynucleotide encoding the receptor
EP01950535A EP1297134A2 (en) 2000-06-27 2001-06-27 Novel human gaba receptors and polynucleotides encoding the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21408300P 2000-06-27 2000-06-27
US60/214,083 2000-06-27

Publications (2)

Publication Number Publication Date
WO2002000720A2 WO2002000720A2 (en) 2002-01-03
WO2002000720A3 true WO2002000720A3 (en) 2003-01-23

Family

ID=22797710

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/020417 WO2002000720A2 (en) 2000-06-27 2001-06-27 Novel human gaba receptors and polynucleotides encoding the same

Country Status (6)

Country Link
US (1) US7074591B2 (en)
EP (1) EP1297134A2 (en)
JP (1) JP2004510412A (en)
AU (2) AU7151601A (en)
CA (1) CA2415761A1 (en)
WO (1) WO2002000720A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030077773A1 (en) * 2000-12-06 2003-04-24 Brandon Rhonda C. Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
CN110577988B (en) * 2019-07-19 2022-12-20 南方医科大学 Fetal growth restriction prediction model
CN111518883B (en) * 2020-04-02 2022-12-30 深圳大学 Plasma miRNA marker for coronary heart disease diagnosis and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049293A1 (en) * 1997-04-25 1998-11-05 Merck Sharp & Dohme Limited Human theta subunit of the gaba-a receptor

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215051A (en) * 1979-08-29 1980-07-29 Standard Oil Company (Indiana) Formation, purification and recovery of phthalic anhydride
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4873191A (en) * 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
DE3301833A1 (en) * 1983-01-20 1984-07-26 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig METHOD FOR SIMULTANEOUS SYNTHESIS OF SEVERAL OLIGONOCLEOTIDES IN A SOLID PHASE
US4713326A (en) * 1983-07-05 1987-12-15 Molecular Diagnostics, Inc. Coupling of nucleic acids to solid support by photochemical methods
US4594595A (en) * 1984-04-18 1986-06-10 Sanders Associates, Inc. Circular log-periodic direction-finder array
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) * 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5252743A (en) * 1989-11-13 1993-10-12 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
US6075181A (en) * 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6150584A (en) * 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US5877397A (en) * 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5837458A (en) * 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
DE69533135T2 (en) * 1994-07-15 2005-06-16 Cephalon, Inc. IN BACULOVIRUS EXPRESSIVE ACTIVE CALPAIN
US5908635A (en) * 1994-08-05 1999-06-01 The United States Of America As Represented By The Department Of Health And Human Services Method for the liposomal delivery of nucleic acids
US5556752A (en) * 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US5948767A (en) * 1994-12-09 1999-09-07 Genzyme Corporation Cationic amphiphile/DNA complexes
WO1999042580A2 (en) 1998-02-20 1999-08-26 Smithkline Beecham Corporation Gaba receptors and their uses

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049293A1 (en) * 1997-04-25 1998-11-05 Merck Sharp & Dohme Limited Human theta subunit of the gaba-a receptor

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHEBIB MARY ET AL: "The 'ABC' of GABA receptors: A brief review", CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, XX, XX, vol. 26, no. 11, November 1999 (1999-11-01), pages 937 - 940, XP002168993 *
GABRYS B: "GABA receptors", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER TRENDS JOURNAL, CAMBRIDGE, GB, vol. 18, no. SUPPLEMENT, 1997, pages 42 - 43, XP004055261, ISSN: 0165-6147 *
KOFUJI P ET AL: "GENERATION OF TWO FORMS OF THE GAMMA AMINOBUTYRIC ACID RECEPTOR GAMMA-2-SUBUNIT IN MICE BY ALTERNATIVE SPLICING", JOURNAL OF NEUROCHEMISTRY, vol. 56, no. 2, 1991, pages 713 - 715, XP008003427, ISSN: 0022-3042 *
WANG JIA BEI ET AL: "The GABAA receptor gamma1-subunit in seizure prone (DBA/2) and resistant (C57BL/6) mice.", BRAIN RESEARCH BULLETIN, vol. 45, no. 4, 1 March 1998 (1998-03-01), pages 421 - 425, XP002199263, ISSN: 0361-9230 *
YMER S ET AL: "STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF THE GAMMA-1 SUBUNIT OF GABA-A BENZODIAZEPINE RECEPTORS", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, vol. 9, no. 10, 1990, pages 3261 - 3267, XP002199264, ISSN: 0261-4189 *

Also Published As

Publication number Publication date
US20020082407A1 (en) 2002-06-27
US7074591B2 (en) 2006-07-11
WO2002000720A2 (en) 2002-01-03
EP1297134A2 (en) 2003-04-02
CA2415761A1 (en) 2002-01-03
AU7151601A (en) 2002-01-08
AU2001271516B2 (en) 2006-08-03
JP2004510412A (en) 2004-04-08

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