WO2002000345A3 - Automatic pipette with tip identification and detipping mechanism - Google Patents

Automatic pipette with tip identification and detipping mechanism Download PDF

Info

Publication number
WO2002000345A3
WO2002000345A3 PCT/US2001/018026 US0118026W WO0200345A3 WO 2002000345 A3 WO2002000345 A3 WO 2002000345A3 US 0118026 W US0118026 W US 0118026W WO 0200345 A3 WO0200345 A3 WO 0200345A3
Authority
WO
WIPO (PCT)
Prior art keywords
tip
nozzle
type
detipping
detecting
Prior art date
Application number
PCT/US2001/018026
Other languages
French (fr)
Other versions
WO2002000345A2 (en
Inventor
Richard A Cronenberg
Dennis Mitchell
Original Assignee
Vistalab Technologies Inc
Richard A Cronenberg
Dennis Mitchell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vistalab Technologies Inc, Richard A Cronenberg, Dennis Mitchell filed Critical Vistalab Technologies Inc
Priority to AU2001275195A priority Critical patent/AU2001275195A1/en
Priority to JP2002505118A priority patent/JP2004501745A/en
Priority to EP01941878A priority patent/EP1296762A2/en
Publication of WO2002000345A2 publication Critical patent/WO2002000345A2/en
Publication of WO2002000345A3 publication Critical patent/WO2002000345A3/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0275Interchangeable or disposable dispensing tips
    • B01L3/0279Interchangeable or disposable dispensing tips co-operating with positive ejection means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • B01L2200/143Quality control, feedback systems
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/02Identification, exchange or storage of information
    • B01L2300/021Identification, e.g. bar codes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0474Details of actuating means for conveyors or pipettes
    • G01N2035/0491Position sensing, encoding; closed-loop control
    • G01N2035/0493Locating samples; identifying different tube sizes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/103General features of the devices using disposable tips
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

Abstract

Mechanisms are provided for automatically removing tips from a pipette nozzle and/or for detecting the type of tip mounted to the nozzle. For detipping, mechanical energy is stored when the tip is mounted to the nozzle and is released when the tip is to be removed to facilitate removal thereof. A mechanism is preferably provided which limits the force with which the tip is mounted to the nozzle and an overforce mechanism may be provided to facilitate removal of a stuck tip. For detecting tip type, each tip type has a different base configuration which results in a different relative displacement between the nozzle and a surrounding component as a result of the tip contacting both during tip mounting, the difference in relative displacement being detected to identify tip type.
PCT/US2001/018026 2000-06-26 2001-06-04 Automatic pipette with tip identification and detipping mechanism WO2002000345A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2001275195A AU2001275195A1 (en) 2000-06-26 2001-06-04 Automatic pipette identification and detipping
JP2002505118A JP2004501745A (en) 2000-06-26 2001-06-04 Automatic pipette identification and tip removal
EP01941878A EP1296762A2 (en) 2000-06-26 2001-06-04 Automatic pipette with tip identification and detipping mechanism

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21420600P 2000-06-26 2000-06-26
US60/214,206 2000-06-26

Publications (2)

Publication Number Publication Date
WO2002000345A2 WO2002000345A2 (en) 2002-01-03
WO2002000345A3 true WO2002000345A3 (en) 2002-06-20

Family

ID=22798204

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/018026 WO2002000345A2 (en) 2000-06-26 2001-06-04 Automatic pipette with tip identification and detipping mechanism

Country Status (5)

Country Link
US (3) US6749812B2 (en)
EP (1) EP1296762A2 (en)
JP (1) JP2004501745A (en)
AU (1) AU2001275195A1 (en)
WO (1) WO2002000345A2 (en)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19917375C2 (en) * 1999-04-16 2001-09-27 Hamilton Bonaduz Ag Bonaduz Pipetting unit
DE69911474T2 (en) * 1999-05-18 2004-07-22 Socorex Isba S.A., PIPETTE WITH DEVICE FOR EJECTING PIPETTE TIPS
FI108281B (en) * 1999-07-07 2001-12-31 Biohit Oyj Suction device and method for use in a suction device
US6532837B1 (en) * 2000-02-03 2003-03-18 Rainin Instrument, Llc Pipette device with tip ejector utilizing stored energy
US7416704B2 (en) * 2000-06-26 2008-08-26 Vistalab Technologies, Inc. Handheld pipette
US6749812B2 (en) * 2000-06-26 2004-06-15 Vistalab Technologies Automatic pipette detipping
JP4271835B2 (en) * 2000-08-18 2009-06-03 アークレイ株式会社 Pipette device
WO2002085521A1 (en) * 2001-04-25 2002-10-31 Oyster Bay Pump Works, Inc. Reagent addition system and method
US7335337B1 (en) * 2001-09-11 2008-02-26 Smith James C Ergonomic pipette tip and adapters
DE60237627D1 (en) * 2001-10-16 2010-10-21 Matrix Technologies Corp HAND-pipetting
US7284454B2 (en) * 2004-05-27 2007-10-23 Matrix Technologies Corporation Hand held pipette
US20060027033A1 (en) * 2002-10-16 2006-02-09 Richard Cote Hand-held pipette employing voice recognition control
FI120861B (en) * 2002-11-08 2010-04-15 Biohit Oyj multichannel pipette
DE10330985A1 (en) * 2003-07-09 2005-02-17 Tecpharma Licensing Ag Device for administering a fluid product with optical scanning
DE102004003433B4 (en) * 2004-01-21 2006-03-23 Eppendorf Ag Pipetting device with a discharge device for pipette tips
US7641859B2 (en) 2004-02-11 2010-01-05 Matrix Technologies Corporation Pipette tip mounting and ejection assembly and associated pipette tip
CA2512353A1 (en) * 2004-07-16 2006-01-16 Stemcell Technologies Inc. Automated pipette machine
EP1688180B1 (en) * 2005-02-04 2009-09-09 Roche Diagnostics GmbH Pipette for disposable tips of different size
MX338460B (en) 2005-12-21 2016-04-15 Meso Scale Technologies Llc Assay apparatuses, methods and reagents.
PL1887330T3 (en) * 2006-08-11 2010-05-31 Biohit Oyj Method for testing pipettes
US7662344B2 (en) 2006-10-24 2010-02-16 Viaflo Corporation Locking pipette tip and mounting shaft
US7662343B2 (en) * 2006-10-24 2010-02-16 Viaflo Corporation Locking pipette tip and mounting shaft
US7794664B2 (en) 2006-11-16 2010-09-14 Idexx Laboratories, Inc. Pipette tip
GB0717452D0 (en) * 2007-09-07 2007-10-17 Mole Genetics As Separation apparatus
GB0717462D0 (en) * 2007-09-07 2007-10-17 Mole Genetics As Liquid delivery apparatus
US20090071267A1 (en) * 2007-09-17 2009-03-19 Greg Mathus Pipette tip ejection mechanism
USD620602S1 (en) 2008-01-03 2010-07-27 Vistalab Technologies, Inc. Pipette
WO2010025456A1 (en) * 2008-08-29 2010-03-04 Eads Na Defense Security And Systems Solutions, Inc. Automated management of compliance of a target asset to predetermined requirements
US8277757B2 (en) * 2009-09-29 2012-10-02 Integra Biosciences Corp. Pipette tip mounting shaft
US8236256B2 (en) 2010-04-27 2012-08-07 Thomas Friedlander Apparatus and method for efficient and precise transfer of liquids
EP3660517B1 (en) 2010-11-23 2024-04-03 Andrew Alliance S.A Apparatus for programmable manipulation of pipettes
WO2012162101A1 (en) * 2011-05-20 2012-11-29 Geneforge, Inc. Drop-in nozzle
PL2633913T3 (en) * 2012-03-01 2020-03-31 Eppendorf Ag Pipette device and multi-channel pipette device
MX2012010987A (en) * 2012-09-24 2014-03-24 Diana Elizabeth Calva Mendez Pipette comprising a mobile nozzle.
EP3112026B1 (en) * 2015-06-30 2018-03-14 Sartorius Biohit Liquid Handling Oy Pipette with a tip removal mechanism, a method for removing a tip, and a method for pipetting
CN106582907B (en) * 2015-10-15 2021-05-18 常州福生生物技术有限公司 Pipette capable of automatically withdrawing suction head
US11235318B2 (en) 2016-06-15 2022-02-01 Hamilton Company Pipetting device, pipette tip coupler, and pipette tip: devices and methods
US11065614B2 (en) 2016-06-15 2021-07-20 Hamilton Company Pipetting device, pipette tip coupler, and pipette tip: devices and methods
CN109562372A (en) 2016-06-15 2019-04-02 汉密尔顿公司 Liquid-transfering device, pipette tip connector and pipette tip: device and method
US10898892B2 (en) 2016-06-15 2021-01-26 Hamilton Company Pipetting device, pipette tip coupler, and pipette tip: devices and methods
CH712735A1 (en) * 2016-07-22 2018-01-31 Tecan Trading Ag Pipetting device with a liquid volume sensor and liquid processing system.
CH712764A2 (en) 2016-07-22 2018-01-31 Tecan Trading Ag Pipette tip comprising a volume measuring electrode and method for their preparation and pipetting device.
WO2018015419A1 (en) * 2016-07-22 2018-01-25 Tecan Trading Ag Pipette tip for an automated pipetting device and production method thereof
EP3560596A1 (en) * 2018-04-23 2019-10-30 Eppendorf AG Pipette for use with a pipette tip and pipette family comprising multiple pipettes with different nominal volumes
US11911767B2 (en) 2019-10-25 2024-02-27 Mettler-Toledo Rainin, LLC Positive displacement pipette syringe identification system
US11369954B2 (en) 2019-10-25 2022-06-28 Mettler-Toledo Rainin, LLC Powered positive displacement pipette assembly
US11446672B2 (en) 2019-10-25 2022-09-20 Mettler-Toledo Rainin, LLC Powered positive displacement pipette syringe piston grasping mechanism
US11471878B2 (en) 2019-10-25 2022-10-18 Mettler-Toledo Rainin, LLC Powered positive displacement pipette
US11389792B2 (en) 2019-10-25 2022-07-19 Mettler-Toledo Rainin, LLC Syringe for powered positive displacement pipette
EP3831486A1 (en) 2019-12-06 2021-06-09 Eppendorf AG Pipette tip family comprising pipette tips for use with pipettes of a pipette family and pipette family comprising pipettes for use with pipette tips of a pipette tip family
EP3851191A1 (en) * 2020-01-17 2021-07-21 Eppendorf AG Plunger lift pipette, data processing apparatus and system and method for operating a plunger-lift pipette
DE102020104422A1 (en) 2020-02-19 2021-08-19 Hamilton Bonaduz Ag Method for assigning a pipette tip to a pipette tip class based on its pneumatic behavior
DE202021101129U1 (en) 2021-03-05 2022-06-08 Brand Gmbh + Co Kg pipetting device

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991617A (en) * 1974-10-15 1976-11-16 Marteau D Autry Eric J H Device for ejecting the removable tip of a pipette
US4151750A (en) * 1977-02-17 1979-05-01 Kommandiittiyhtio Finnpipette Osmo A. Suovaniemi Device for detaching and removing a disposable tip of a pipette
US4478094A (en) * 1983-01-21 1984-10-23 Cetus Corporation Liquid sample handling system
GB2172218A (en) * 1985-02-15 1986-09-17 Rocket Of London Ltd Pipetter tips for pipetters
US4821586A (en) * 1988-02-25 1989-04-18 Medical Laboratory Automation, Inc. Programmable pipette
EP0421785A2 (en) * 1989-10-04 1991-04-10 Drummond Scientific Company Pipetter device
EP0437906A1 (en) * 1990-01-17 1991-07-24 Minoru Atake System for measuring liquid
US5620661A (en) * 1993-12-10 1997-04-15 Eppendorf-Netherler-Hinz Gmbh Pipette system
WO2001057490A1 (en) * 2000-02-03 2001-08-09 Rainin Instrument Llc. Pipette device with tip ejector utilizing stored energy

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US586781A (en) 1897-07-20 Housek
US1923279A (en) * 1931-08-01 1933-08-22 Sameshima Naotaro Laundry sprayer
US2066977A (en) * 1935-04-27 1937-01-05 Lawrence E Iler Liquid dispenser
US2086348A (en) * 1936-09-26 1937-07-06 Bernhardt Rudolph Spraying apparatus
US2091404A (en) * 1936-12-02 1937-08-31 Fred L Hicks Pipette
US2710658A (en) * 1950-07-24 1955-06-14 Charles K Huthsing Fire extinguisher
US2876204A (en) * 1951-12-07 1959-03-03 Exxon Research Engineering Co Wax-polyethylene-polyisobutylene
US2876846A (en) 1955-11-29 1959-03-10 Gen Pacific Corp Fire extinguisher head assembly
US2796204A (en) * 1956-05-10 1957-06-18 Math Moe Dispenser cap for containers
US3039500A (en) * 1959-01-22 1962-06-19 Goldberg Moshe Levy Pipette filling and liquid dispensing device
US3134506A (en) * 1960-11-07 1964-05-26 David G Way Holder and puncturing device for cans
US3129854A (en) * 1961-08-21 1964-04-21 Drackett Co Dispensing device
US3246559A (en) * 1961-12-26 1966-04-19 Beckman Instruments Inc Force feed cuvette
US3244009A (en) * 1963-08-22 1966-04-05 Becton Dickinson Co Automatic pipette
US3251420A (en) * 1964-04-20 1966-05-17 Fire Guard Corp Fire extinguisher with bottom mounted cartridge
US3719087A (en) * 1966-04-08 1973-03-06 R Thiers Pipetting apparatus and method
US3757585A (en) * 1968-08-16 1973-09-11 Heller Labor Pipette apparatus
US3558014A (en) * 1968-10-15 1971-01-26 Bio Logics Inc Automatic proportioner
US3732735A (en) 1971-06-17 1973-05-15 Medical Laboratory Automation Pipettes
US3754687A (en) * 1971-09-21 1973-08-28 Kontes Glass Co A multi-positional pipetting dispenser
US3853012A (en) 1971-10-04 1974-12-10 Medical Laboratory Automation Pipettes
US3786683A (en) * 1972-09-12 1974-01-22 Alphamedics Mfg Corp Hand-operated pipette
US3933048A (en) 1974-02-12 1976-01-20 Medical Laboratory Automation, Inc. Pipettes
US3983375A (en) * 1974-05-22 1976-09-28 The United States Of America As Represented By The Secretary Of The Army Tiltester
US3954014A (en) 1974-12-16 1976-05-04 Becton, Dickinson And Company Multiple shot pipetter
US4369665A (en) * 1978-01-11 1983-01-25 Indicon Inc. Manually holdable automatic pipette
US4164870A (en) 1978-04-10 1979-08-21 Medical Laboratory Automation, Inc. Pipettes
FI56937C (en) * 1978-08-04 1980-05-12 Suovaniemi Finnpipette PIPETT ANORDNING FOER ATT AVLAEGSNA EN ENGAONGSSPETSBEHAOLLARE FRAON EN PIPETT
SE7809267L (en) * 1978-09-04 1980-03-05 Lkb Clinicon Ab MOTORPIPETT
FI76710B (en) * 1978-09-08 1988-08-31 Osmo Antero Suovaniemi Pipette.
US4257267A (en) 1978-10-18 1981-03-24 Bohr Scientific Corporation Dispenser unit with lockable actuating lever
US4257268A (en) * 1979-08-24 1981-03-24 Data Packaging Corporation Pipetter
US4528161A (en) * 1981-08-31 1985-07-09 American Hospital Supply Corp. Probe for automated liquid dispenser
US4475666A (en) * 1981-08-31 1984-10-09 American Hospital Supply Corporation Automated liquid dispenser control
US4598840A (en) * 1983-10-11 1986-07-08 Burg Donald E Snap-in cartridge diluter
US4671123A (en) * 1984-02-16 1987-06-09 Rainin Instrument Co., Inc. Methods and apparatus for pipetting and/or titrating liquids using a hand held self-contained automated pipette
US4567780A (en) * 1984-03-12 1986-02-04 American Hospital Supply Corporation Hand-held pipette with disposable capillary
FI844320A (en) * 1984-11-02 1986-05-03 Labsystems Oy UTSPAEDNINGSDOSERINGSANORDNING.
US4679446A (en) * 1985-09-09 1987-07-14 Baxter Travenol Laboratories, Inc. Multi-volume displacement pipette
CH671526A5 (en) 1985-12-17 1989-09-15 Hamilton Bonaduz Ag
JPS62144755A (en) * 1985-12-20 1987-06-27 Fuji Photo Film Co Ltd Re-sucking preventing pipet
FR2607407B1 (en) 1986-11-27 1991-08-02 Marteau D Autry Eric METHOD AND DEVICE FOR CALIBRATING A PIPETTE FOR SAMPLING AND DOSING
US4815541A (en) * 1987-06-29 1989-03-28 Arrington Richard C Fire extinguisher
US4988481A (en) * 1989-01-30 1991-01-29 Labsystems Oy Electrical pipette
US5104624A (en) * 1989-10-20 1992-04-14 Costar Corporation Pipetter
US5585068A (en) * 1990-02-20 1996-12-17 Biochemical Diagnostics, Inc. Apparatus for automatically separating a compound from a plurality of discrete liquid specimens
FI86969C (en) * 1991-02-05 1992-11-10 Biohit Oy pipette
US5214968A (en) * 1992-01-06 1993-06-01 Drummond Scientific Company Pipet filling and discharge device
FI921647A0 (en) 1992-04-13 1992-04-13 Labsystems Oy SPETSDELPIPETT.
US5320810A (en) * 1992-05-13 1994-06-14 Integrated Instrument Services, Inc. Pipette with an axially stationary volume adjusting wheel
FI922939A0 (en) * 1992-06-24 1992-06-24 Labsystems Oy KNAPPIPETT.
US5432085A (en) * 1992-11-10 1995-07-11 Warren; Richard J. Cell feeder/harvester assembly
ATE209052T1 (en) * 1993-06-30 2001-12-15 Hamilton Co MANUAL DISPENSING AID FOR AN INJECTION SYRINGE
US5394789A (en) * 1993-07-08 1995-03-07 Evans; John P. Manually operable device for metering air through a valve system for drawing into, retaining and evacuating material from a chamber
US5509318A (en) * 1993-10-13 1996-04-23 Manostat Corporation Memory Mopet
FR2717447B1 (en) * 1994-03-21 1996-05-31 Labcatal Dosing device intended to deliver constant unit doses.
FR2723700B1 (en) * 1994-08-16 1996-11-15 Marteau D Autry Eric PIPETTE FOR DISPENSING SUCCESSIVE LIQUID VOLUMES
US5673824A (en) * 1995-05-31 1997-10-07 Taplast Srl Plastic dosing pump for dispensing liquids from containers
US5614153A (en) * 1995-05-26 1997-03-25 Rainin Instrument Co., Inc. Pipette tip ejector
US5616871A (en) * 1995-09-28 1997-04-01 Drummond Scientific Company Pipet gun assembly
US20010036425A1 (en) * 1995-10-12 2001-11-01 Michel Gazeau Device for transferring samples of micro-amounts of liquids
US5792424A (en) * 1996-03-05 1998-08-11 Rainin Instrument Co., Inc. Manual pipette with delayed-action home position latch
JP2838070B2 (en) * 1996-03-07 1998-12-16 株式会社ニチリョー Repetitive pipette
US5807524A (en) 1996-08-06 1998-09-15 Rainin Instrument Co., Inc. Pipette tip with pipette surface contamination protector
FI101456B1 (en) 1996-11-13 1998-06-30 Labsystems Oy Flercylinderpipett
US6090348A (en) * 1997-03-14 2000-07-18 Becton, Dickinson And Company Method for programming an electronic pipetter
FI107025B (en) 1998-06-10 2001-05-31 Biohit Oyj Suction device and method for removing the disposable tip
JP2000512249A (en) * 1998-06-19 2000-09-19 アリュアー ホーム クリエイション カンパニー インコーポレイテッド Container with improved structure
US6627446B1 (en) * 1998-07-02 2003-09-30 Amersham Biosciences (Sv) Corp Robotic microchannel bioanalytical instrument
US6787111B2 (en) * 1998-07-02 2004-09-07 Amersham Biosciences (Sv) Corp. Apparatus and method for filling and cleaning channels and inlet ports in microchips used for biological analysis
US6240791B1 (en) * 1998-08-07 2001-06-05 James W. Kenney User-replaceable pipette gun grip
US6132582A (en) * 1998-09-14 2000-10-17 The Perkin-Elmer Corporation Sample handling system for a multi-channel capillary electrophoresis device
US6168761B1 (en) * 1998-11-06 2001-01-02 Rainin Instrument Co., Inc. Pipette with improved pipette tip and mounting shaft
US6197259B1 (en) 1998-11-06 2001-03-06 Rainin Instrument Co., Inc. Easy eject pipette tip
US6299841B1 (en) * 1999-03-05 2001-10-09 Rainin Instrument Co., Inc. Bilaterally symmetrical battery powered microprocessor controlled lightweight hand-holdable electronic pipette
DE19915066C2 (en) * 1999-04-01 2001-09-13 Brand Gmbh & Co Kg Method for recognizing the type of exchangeable device-specific piston-cylinder units for pipetting or dosing devices as well as pipetting and dosing systems
DE19917375C2 (en) * 1999-04-16 2001-09-27 Hamilton Bonaduz Ag Bonaduz Pipetting unit
US7276336B1 (en) * 1999-07-22 2007-10-02 Agilent Technologies, Inc. Methods of fabricating an addressable array of biopolymer probes
US6524531B1 (en) * 1999-09-14 2003-02-25 Pharmacopeia, Inc. Hand-held dispenser/aspirator
US6368872B1 (en) * 1999-10-22 2002-04-09 Tecan Trading Ag Apparatus and method for chemical processing
DE19963141A1 (en) * 1999-12-24 2001-07-12 Brand Gmbh & Co Kg Pipette for a pipetting system
US6428750B1 (en) * 2000-02-17 2002-08-06 Rainin Instrument, Llc Volume adjustable manual pipette with quick set volume adjustment
US6365110B1 (en) * 2000-03-09 2002-04-02 Rainin Instrument Blowout springless manual air displacement pipette with mechanical assist for aiding in locating and maintaining pipette plunger at a home position
US6878554B1 (en) * 2000-03-20 2005-04-12 Perkinelmer Las, Inc. Method and apparatus for automatic pin detection in microarray spotting instruments
US6419123B2 (en) 2000-04-19 2002-07-16 Mary Ellen Colquhoun Liquid soap dispensing container
US6749812B2 (en) * 2000-06-26 2004-06-15 Vistalab Technologies Automatic pipette detipping
US6715369B2 (en) * 2000-08-03 2004-04-06 Nichiryo Co., Ltd. Hybrid pipette
US6861034B1 (en) * 2000-11-22 2005-03-01 Xerox Corporation Priming mechanisms for drop ejection devices
FIU20010274U0 (en) * 2001-07-06 2001-07-06 Biohit Oyj The suction device
DE60237627D1 (en) * 2001-10-16 2010-10-21 Matrix Technologies Corp HAND-pipetting
US6967004B2 (en) * 2001-10-30 2005-11-22 Rainin Instrument, Llc Pipette with improved pipette tip and mounting shaft
US6874699B2 (en) * 2002-10-15 2005-04-05 Wisconsin Alumni Research Foundation Methods and apparata for precisely dispensing microvolumes of fluids
JP4072724B2 (en) * 2003-04-16 2008-04-09 日立工機株式会社 Automatic dispensing device
US7618589B2 (en) * 2004-09-07 2009-11-17 Hitachi Koki Co., Ltd. Automatic dispenser
US7870797B2 (en) * 2006-04-03 2011-01-18 Artel, Inc. Apparatus and method for aspirating and dispensing liquid

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991617A (en) * 1974-10-15 1976-11-16 Marteau D Autry Eric J H Device for ejecting the removable tip of a pipette
US4151750A (en) * 1977-02-17 1979-05-01 Kommandiittiyhtio Finnpipette Osmo A. Suovaniemi Device for detaching and removing a disposable tip of a pipette
US4478094A (en) * 1983-01-21 1984-10-23 Cetus Corporation Liquid sample handling system
US4478094B1 (en) * 1983-01-21 1988-04-19
GB2172218A (en) * 1985-02-15 1986-09-17 Rocket Of London Ltd Pipetter tips for pipetters
US4821586A (en) * 1988-02-25 1989-04-18 Medical Laboratory Automation, Inc. Programmable pipette
EP0421785A2 (en) * 1989-10-04 1991-04-10 Drummond Scientific Company Pipetter device
EP0437906A1 (en) * 1990-01-17 1991-07-24 Minoru Atake System for measuring liquid
US5620661A (en) * 1993-12-10 1997-04-15 Eppendorf-Netherler-Hinz Gmbh Pipette system
WO2001057490A1 (en) * 2000-02-03 2001-08-09 Rainin Instrument Llc. Pipette device with tip ejector utilizing stored energy

Also Published As

Publication number Publication date
EP1296762A2 (en) 2003-04-02
US20060104866A1 (en) 2006-05-18
US20040094638A1 (en) 2004-05-20
JP2004501745A (en) 2004-01-22
US8114362B2 (en) 2012-02-14
US6749812B2 (en) 2004-06-15
US6977062B2 (en) 2005-12-20
WO2002000345A2 (en) 2002-01-03
AU2001275195A1 (en) 2002-01-08
US20020001545A1 (en) 2002-01-03

Similar Documents

Publication Publication Date Title
WO2002000345A3 (en) Automatic pipette with tip identification and detipping mechanism
HK1108673A1 (en) Cassette locking and ejecting arrangement
WO2004091798A3 (en) Centrifuge adapter
EP1541088A4 (en) Piercing unit, piercing member removal device, and piercing device
WO2005120184A3 (en) Deployment apparatus and method
DE60041663D1 (en) Device for detecting the occupants of a vehicle
WO2004102158A3 (en) Raised surface assay plate
WO1999035505A3 (en) Method for removing accumulated solder from probe card probing features
CA2556884A1 (en) Strip ejection system
CA2246576A1 (en) Apparatus for discharging the card body
DE60034269D1 (en) Liquid ejection head, its manufacturing method and microelectromechanical device
EP1148318A3 (en) Automatic liquid level detection device
WO2004020939A3 (en) Method of scanning an object
EP0849586A3 (en) Detection of substances on surfaces and electrodes therefor
JP2009543264A (en) Device for gripping compact discs or other objects
AU2001250455A1 (en) Liquid sample pipette with tip ejecting mechanism
WO2004040260A3 (en) Raised surface assay plate
EP0922927A3 (en) Measuring device for vehicles
AU2001286756A1 (en) Device for identifying the presence of a nucleotide sequence in a dna sample
SI1222467T1 (en) Leptin assay based on detecting ang-2 expression
DE59908835D1 (en) DEVICE FOR DETECTING THE AXIAL GAME
WO1999005984A3 (en) Tool operating device, in particular for use in dentistry
AU2003264712A1 (en) Device for detecting the nature of a blow and measuring its force, method for using same and use thereof for refereeing a sport
DE60217634D1 (en) Device for detecting premature atrial contractions
WO2006078393A3 (en) A tool having an ejection assembly

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

ENP Entry into the national phase

Ref country code: JP

Ref document number: 2002 505118

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 2001941878

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2001941878

Country of ref document: EP