WO2001087134A3 - Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart - Google Patents

Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart Download PDF

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Publication number
WO2001087134A3
WO2001087134A3 PCT/IL2001/000417 IL0100417W WO0187134A3 WO 2001087134 A3 WO2001087134 A3 WO 2001087134A3 IL 0100417 W IL0100417 W IL 0100417W WO 0187134 A3 WO0187134 A3 WO 0187134A3
Authority
WO
WIPO (PCT)
Prior art keywords
heart
cardiac
contractility modulating
delivery
cardiac contractility
Prior art date
Application number
PCT/IL2001/000417
Other languages
French (fr)
Other versions
WO2001087134A2 (en
Inventor
Ziv Belsky
Yuval Mika
Original Assignee
Impulse Dynamics Nv
Ziv Belsky
Yuval Mika
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Impulse Dynamics Nv, Ziv Belsky, Yuval Mika filed Critical Impulse Dynamics Nv
Priority to DE60129130T priority Critical patent/DE60129130T2/en
Priority to AU56631/01A priority patent/AU5663101A/en
Priority to EP01929956A priority patent/EP1284786B1/en
Publication of WO2001087134A2 publication Critical patent/WO2001087134A2/en
Publication of WO2001087134A3 publication Critical patent/WO2001087134A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7217—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3627—Heart stimulators for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
    • A61N1/3962—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion in combination with another heart therapy
    • A61N1/39622—Pacing therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346—Analysis of electrocardiograms
    • A61B5/349—Detecting specific parameters of the electrocardiograph cycle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Signal Processing (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Psychiatry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Hospice & Palliative Care (AREA)
  • Electrotherapy Devices (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Credit Cards Or The Like (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

A method and device for controlling the delivery of cardiac contractility modulating signals to the heart. The method includes applying electrodes to a heart, sensing electrical activity in a first cardiac chamber and in at least a second cardiac chamber to detect events within a cardiac beat cycle and applying a cardiac contractility modulating signal to the heart at or about the first cardiac chamber in response to detecting an event within an alert window time interval. The applying of the cardiac contractility modulating signal is inhibited in response to detecting one or more inhibitory events occurring within specific time intervals defined within a current beat cycle.
PCT/IL2001/000417 2000-05-16 2001-05-10 Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart WO2001087134A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE60129130T DE60129130T2 (en) 2000-05-16 2001-05-10 DEVICE AND METHOD FOR REGULATING THE ADMINISTRATION OF NON -TEXCITATORY, CARDIAL, CONTRACTION-MODULATING SIGNALS TO A HEART
AU56631/01A AU5663101A (en) 2000-05-16 2001-05-10 Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to heart
EP01929956A EP1284786B1 (en) 2000-05-16 2001-05-10 Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/572,482 2000-05-16
US09/572,482 US6370430B1 (en) 1999-03-25 2000-05-16 Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart

Publications (2)

Publication Number Publication Date
WO2001087134A2 WO2001087134A2 (en) 2001-11-22
WO2001087134A3 true WO2001087134A3 (en) 2002-05-02

Family

ID=24288013

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2001/000417 WO2001087134A2 (en) 2000-05-16 2001-05-10 Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart

Country Status (6)

Country Link
US (1) US6370430B1 (en)
EP (1) EP1284786B1 (en)
AT (1) ATE365573T1 (en)
AU (1) AU5663101A (en)
DE (1) DE60129130T2 (en)
WO (1) WO2001087134A2 (en)

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US7840264B1 (en) 1996-08-19 2010-11-23 Mr3 Medical, Llc System and method for breaking reentry circuits by cooling cardiac tissue
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US6480737B1 (en) 1999-12-29 2002-11-12 Impulse Dynamics Nv Field delivery safety system using detection of atypical ECG
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Also Published As

Publication number Publication date
AU5663101A (en) 2001-11-26
DE60129130T2 (en) 2008-03-06
EP1284786B1 (en) 2007-06-27
DE60129130D1 (en) 2007-08-09
EP1284786A2 (en) 2003-02-26
EP1284786A4 (en) 2004-12-15
ATE365573T1 (en) 2007-07-15
US6370430B1 (en) 2002-04-09
WO2001087134A2 (en) 2001-11-22

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