WO2001054735A3 - Gel-infused sponges for tissue repair and augmentation - Google Patents

Gel-infused sponges for tissue repair and augmentation Download PDF

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Publication number
WO2001054735A3
WO2001054735A3 PCT/US2001/002837 US0102837W WO0154735A3 WO 2001054735 A3 WO2001054735 A3 WO 2001054735A3 US 0102837 W US0102837 W US 0102837W WO 0154735 A3 WO0154735 A3 WO 0154735A3
Authority
WO
WIPO (PCT)
Prior art keywords
gel
augmentation
tissue repair
infused
sponges
Prior art date
Application number
PCT/US2001/002837
Other languages
French (fr)
Other versions
WO2001054735A2 (en
Inventor
Hanne Bentz
A Minerva Garcia
Jeffrey A Hubbell
Original Assignee
Orthogene Inc
Hanne Bentz
A Minerva Garcia
Jeffrey A Hubbell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orthogene Inc, Hanne Bentz, A Minerva Garcia, Jeffrey A Hubbell filed Critical Orthogene Inc
Priority to AU2001234623A priority Critical patent/AU2001234623A1/en
Publication of WO2001054735A2 publication Critical patent/WO2001054735A2/en
Publication of WO2001054735A3 publication Critical patent/WO2001054735A3/en
Priority to US10/207,439 priority patent/US20030095993A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3821—Bone-forming cells, e.g. osteoblasts, osteocytes, osteoprogenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3847—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges

Abstract

Gel-infused sponge matrix comprising an absorbable sponge material, a gel and an active ingredient are disclosed, as are methods of enhancing tissue repair, regeneration or augmentation using the gel-infused sponge.
PCT/US2001/002837 2000-01-28 2001-01-26 Gel-infused sponges for tissue repair and augmentation WO2001054735A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001234623A AU2001234623A1 (en) 2000-01-28 2001-01-26 Gel-infused sponges for tissue repair and augmentation
US10/207,439 US20030095993A1 (en) 2000-01-28 2002-07-26 Gel-infused sponges for tissue repair and augmentation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17864600P 2000-01-28 2000-01-28
US60/178,646 2000-01-28

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/207,439 Continuation US20030095993A1 (en) 2000-01-28 2002-07-26 Gel-infused sponges for tissue repair and augmentation

Publications (2)

Publication Number Publication Date
WO2001054735A2 WO2001054735A2 (en) 2001-08-02
WO2001054735A3 true WO2001054735A3 (en) 2001-12-20

Family

ID=22653340

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/002837 WO2001054735A2 (en) 2000-01-28 2001-01-26 Gel-infused sponges for tissue repair and augmentation

Country Status (2)

Country Link
AU (1) AU2001234623A1 (en)
WO (1) WO2001054735A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9265858B2 (en) 2012-06-12 2016-02-23 Ferrosan Medical Devices A/S Dry haemostatic composition
US9533069B2 (en) 2008-02-29 2017-01-03 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6599515B1 (en) 1995-01-16 2003-07-29 Baxter International Inc. Fibrin porous structure
US6965014B1 (en) 1996-01-16 2005-11-15 Baxter International Inc. Fibrin material and method for producing and using the same
US20140193468A1 (en) * 2001-03-23 2014-07-10 Histogenics Corporation Methods for preparation of neo-cartilage constructs
JP3646162B2 (en) * 2001-07-04 2005-05-11 独立行政法人産業技術総合研究所 Transplant for cartilage tissue regeneration
DE102005030614B4 (en) 2005-06-30 2014-05-08 Biotissue Ag Cell-free graft, its use, process for its preparation, matrix thus produced with gel and process for the preparation of this matrix with gel
EP1968499A1 (en) * 2005-12-14 2008-09-17 Anika Therapeutics Inc. Bioabsorbable implant of hyaluronic acid derivative for treatment of osteochondral and chondral defects
EP1968498A2 (en) * 2005-12-14 2008-09-17 Anika Therapeutics Inc. Meniscal implant of hyaluronic acid derivatives for treatment of meniscal defects
CA2643084C (en) * 2006-03-01 2015-12-29 Fmc Biopolymer As Gelled composite comprising pores and gel within the pores, method of manufacture and use thereof
DE102006047346A1 (en) * 2006-10-06 2008-04-10 Transtissue Technologies Gmbh Matrix gel graft without cells
US20090054984A1 (en) 2007-08-20 2009-02-26 Histogenics Corporation Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects
EP2522376B1 (en) * 2008-10-17 2020-01-08 Sofradim Production Method for preparing auto-sealant matrix for tissue repair
WO2010060104A2 (en) * 2008-11-24 2010-05-27 Moma Therapeutics Implantable liposome embedded matrix composition, uses thereof, and polycaprolactone praticles as scaffolds for tissue regeneration
WO2010095052A2 (en) 2009-02-21 2010-08-26 Sofradim Production Compounds and medical devices activated with solvophobic linkers
JP6241624B2 (en) 2012-03-06 2017-12-06 フェロサン メディカル デバイシーズ エイ／エス Pressurized container containing hemostatic paste
AU2014283170B2 (en) 2013-06-21 2017-11-02 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
CA2928963C (en) 2013-12-11 2020-10-27 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
JP6726852B2 (en) 2014-10-13 2020-07-22 フェッローサン メディカル ディバイス エー／エス Dry composition for use in hemostasis and wound healing
JP6747650B2 (en) 2014-12-24 2020-08-26 フェロサン メディカル デバイシーズ エイ／エス Syringe for holding and mixing the first substance and the second substance
CA2986981A1 (en) 2015-07-03 2017-01-12 Ferrosan Medical Devices A/S Syringe for mixing two components and for retaining a vacuum in a storage condition
US11129790B2 (en) 2017-05-19 2021-09-28 Northeastern University Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates
JP7395113B2 (en) 2018-05-09 2023-12-11 フェロサン メディカル デバイシーズ エイ／エス Method of preparing a hemostatic composition

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451397A (en) * 1981-11-30 1984-05-29 Centre Technique Du Cuir Method of preparing collagen products
US4703108A (en) * 1984-03-27 1987-10-27 University Of Medicine & Dentistry Of New Jersey Biodegradable matrix and methods for producing same
FR2657352A1 (en) * 1990-01-25 1991-07-26 France Etat Armement New biological product for replacement of connective tissue, with a composite structure based on collagen, and process for its preparation
US5512301A (en) * 1992-05-01 1996-04-30 Amgen Inc. Collagen-containing sponges as drug delivery compositions for proteins
WO1996025961A1 (en) * 1995-02-22 1996-08-29 Ed Geistlich Söhne Ag Für Chemische Industrie Resorbable extracellular matrix for reconstruction of cartilage tissue
US5645849A (en) * 1993-11-03 1997-07-08 Clarion Pharmaceuticals, Inc. Hemostatic patch
WO1998040111A1 (en) * 1997-03-07 1998-09-17 University College London Tissue implant

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4451397A (en) * 1981-11-30 1984-05-29 Centre Technique Du Cuir Method of preparing collagen products
US4703108A (en) * 1984-03-27 1987-10-27 University Of Medicine & Dentistry Of New Jersey Biodegradable matrix and methods for producing same
FR2657352A1 (en) * 1990-01-25 1991-07-26 France Etat Armement New biological product for replacement of connective tissue, with a composite structure based on collagen, and process for its preparation
US5512301A (en) * 1992-05-01 1996-04-30 Amgen Inc. Collagen-containing sponges as drug delivery compositions for proteins
US5645849A (en) * 1993-11-03 1997-07-08 Clarion Pharmaceuticals, Inc. Hemostatic patch
WO1996025961A1 (en) * 1995-02-22 1996-08-29 Ed Geistlich Söhne Ag Für Chemische Industrie Resorbable extracellular matrix for reconstruction of cartilage tissue
WO1998040111A1 (en) * 1997-03-07 1998-09-17 University College London Tissue implant

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9533069B2 (en) 2008-02-29 2017-01-03 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
US9265858B2 (en) 2012-06-12 2016-02-23 Ferrosan Medical Devices A/S Dry haemostatic composition

Also Published As

Publication number Publication date
WO2001054735A2 (en) 2001-08-02
AU2001234623A1 (en) 2001-08-07

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