WO2001036007A3 - Compositions of a combination of radioactive therapy and cell-cycle inhibitors - Google Patents

Compositions of a combination of radioactive therapy and cell-cycle inhibitors Download PDF

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Publication number
WO2001036007A3
WO2001036007A3 PCT/CA2000/001333 CA0001333W WO0136007A3 WO 2001036007 A3 WO2001036007 A3 WO 2001036007A3 CA 0001333 W CA0001333 W CA 0001333W WO 0136007 A3 WO0136007 A3 WO 0136007A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
cell
combination
cycle inhibitors
radioactive therapy
Prior art date
Application number
PCT/CA2000/001333
Other languages
French (fr)
Other versions
WO2001036007A2 (en
Inventor
William L Hunter
Richard Liggins
Original Assignee
Angiotech Pharm Inc
William L Hunter
Richard Liggins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiotech Pharm Inc, William L Hunter, Richard Liggins filed Critical Angiotech Pharm Inc
Priority to JP2001537997A priority Critical patent/JP2003513756A/en
Priority to AU13746/01A priority patent/AU1374601A/en
Priority to CA002388844A priority patent/CA2388844A1/en
Priority to EP00975703A priority patent/EP1235598A2/en
Publication of WO2001036007A2 publication Critical patent/WO2001036007A2/en
Publication of WO2001036007A3 publication Critical patent/WO2001036007A3/en
Priority to HK03101586.5A priority patent/HK1049443A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1027—Interstitial radiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019—Sources therefor
    • A61N2005/1023—Means for creating a row of seeds, e.g. spacers

Abstract

Disclosed herein are therapeutic devices, compositions and methods for treating proliferative diseases. For example, within one aspect of the invention therapeutic devices are provided, comprising a device that locally administers radiation, and a cell-cycle inhibitor.
PCT/CA2000/001333 1999-11-12 2000-11-14 Compositions of a combination of radioactive therapy and cell-cycle inhibitors WO2001036007A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2001537997A JP2003513756A (en) 1999-11-12 2000-11-14 Compositions of a combination of radiotherapy and a cell cycle inhibitor
AU13746/01A AU1374601A (en) 1999-11-12 2000-11-14 Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors
CA002388844A CA2388844A1 (en) 1999-11-12 2000-11-14 Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors
EP00975703A EP1235598A2 (en) 1999-11-12 2000-11-14 Compositions of a combination of radioactive therapy and cell-cycle inhibitors
HK03101586.5A HK1049443A1 (en) 1999-11-12 2003-03-04 Compositions of a combination of radioactive therapy and cell-cycle inhibitors

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US16525999P 1999-11-12 1999-11-12
US60/165,259 1999-11-12
US71204700A 2000-11-13 2000-11-13
US09/712,047 2000-11-13

Publications (2)

Publication Number Publication Date
WO2001036007A2 WO2001036007A2 (en) 2001-05-25
WO2001036007A3 true WO2001036007A3 (en) 2002-07-04

Family

ID=26861236

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2000/001333 WO2001036007A2 (en) 1999-11-12 2000-11-14 Compositions of a combination of radioactive therapy and cell-cycle inhibitors

Country Status (7)

Country Link
US (1) US20020055666A1 (en)
EP (1) EP1235598A2 (en)
JP (1) JP2003513756A (en)
AU (1) AU1374601A (en)
CA (1) CA2388844A1 (en)
HK (1) HK1049443A1 (en)
WO (1) WO2001036007A2 (en)

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