WO1998035012A3 - Methods and products for analyzing polymers - Google Patents
Methods and products for analyzing polymers Download PDFInfo
- Publication number
- WO1998035012A3 WO1998035012A3 PCT/US1998/003024 US9803024W WO9835012A3 WO 1998035012 A3 WO1998035012 A3 WO 1998035012A3 US 9803024 W US9803024 W US 9803024W WO 9835012 A3 WO9835012 A3 WO 9835012A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- products
- analyzing polymers
- polymers
- analyzing
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00707—Processes involving means for analysing and characterising the products separated from the reactor apparatus
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6432—Quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6482—Sample cells, cuvettes
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/97—Test strip or test slide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
Abstract
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT98906490T ATE273381T1 (en) | 1997-02-12 | 1998-02-11 | METHOD FOR ANALYZING POLYMERS |
DE69825601T DE69825601T2 (en) | 1997-02-12 | 1998-02-11 | METHOD FOR THE ANALYSIS OF POLYMERS |
EP98906490A EP1009802B1 (en) | 1997-02-12 | 1998-02-11 | Methods for analyzimg polymers |
CA002281205A CA2281205A1 (en) | 1997-02-12 | 1998-02-11 | Methods and products for analyzing polymers |
JP53510498A JP3935509B2 (en) | 1997-02-12 | 1998-02-11 | Methods and products for polymer analysis |
AU61703/98A AU762888B2 (en) | 1997-02-12 | 1998-02-11 | Methods and products for analyzing polymers |
IL15600298A IL156002A0 (en) | 1997-02-12 | 1998-02-11 | Methods and products for analyzing polymers |
IL13133298A IL131332A (en) | 1997-02-12 | 1998-02-11 | Methods and products for analyzing polymers |
US09/134,411 US6355420B1 (en) | 1997-02-12 | 1998-08-13 | Methods and products for analyzing polymers |
US09/852,968 US8168380B2 (en) | 1997-02-12 | 2001-05-10 | Methods and products for analyzing polymers |
US09/928,668 US20020110818A1 (en) | 1997-02-12 | 2001-08-13 | Methods of analyzing polymers using ordered label strategies |
US12/985,905 US20110210272A1 (en) | 1997-02-12 | 2011-01-06 | Methods and Products for Analyzing Polymers |
US13/432,959 US20120217161A1 (en) | 1997-02-12 | 2012-03-28 | Methods and Products for Analyzing Polymers |
US14/034,407 US9745625B2 (en) | 1997-02-12 | 2013-09-23 | Methods and products for analyzing polymers |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3792197P | 1997-02-12 | 1997-02-12 | |
US60/037921 | 1997-02-12 | ||
US6468797P | 1997-11-05 | 1997-11-05 | |
US60/064,687 | 1997-11-05 |
Related Child Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/134,411 Continuation US6355420B1 (en) | 1997-02-12 | 1998-08-13 | Methods and products for analyzing polymers |
US09/134,411 A-371-Of-International US6355420B1 (en) | 1997-02-12 | 1998-08-13 | Methods and products for analyzing polymers |
US09/374,415 Continuation-In-Part US6403311B1 (en) | 1997-02-12 | 1999-08-13 | Methods of analyzing polymers using ordered label strategies |
US09/852,968 Division US8168380B2 (en) | 1997-02-12 | 2001-05-10 | Methods and products for analyzing polymers |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998035012A2 WO1998035012A2 (en) | 1998-08-13 |
WO1998035012A3 true WO1998035012A3 (en) | 1999-02-11 |
Family
ID=26714627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/003024 WO1998035012A2 (en) | 1997-02-12 | 1998-02-11 | Methods and products for analyzing polymers |
Country Status (10)
Country | Link |
---|---|
US (5) | US6355420B1 (en) |
EP (1) | EP1009802B1 (en) |
JP (1) | JP3935509B2 (en) |
CN (1) | CN1251609A (en) |
AT (1) | ATE273381T1 (en) |
AU (1) | AU762888B2 (en) |
CA (1) | CA2281205A1 (en) |
DE (1) | DE69825601T2 (en) |
IL (2) | IL131332A (en) |
WO (1) | WO1998035012A2 (en) |
Cited By (4)
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US8882980B2 (en) | 2008-09-03 | 2014-11-11 | Nabsys, Inc. | Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels |
US9243284B2 (en) | 2000-12-01 | 2016-01-26 | Life Technologies Corporation | Enzymatic nucleic acid synthesis: compositions and methods for inhibiting pyrophosphorolysis |
US9310376B2 (en) | 2007-03-28 | 2016-04-12 | Bionano Genomics, Inc. | Methods of macromolecular analysis using nanochannel arrays |
US9536041B2 (en) | 2008-06-30 | 2017-01-03 | Bionano Genomics, Inc. | Methods and devices for single-molecule whole genome analysis |
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US8168380B2 (en) | 2012-05-01 |
JP3935509B2 (en) | 2007-06-27 |
US20140199209A1 (en) | 2014-07-17 |
US6355420B1 (en) | 2002-03-12 |
JP2001514739A (en) | 2001-09-11 |
AU6170398A (en) | 1998-08-26 |
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EP1009802A2 (en) | 2000-06-21 |
CN1251609A (en) | 2000-04-26 |
DE69825601D1 (en) | 2004-09-16 |
US20120217161A1 (en) | 2012-08-30 |
WO1998035012A2 (en) | 1998-08-13 |
IL131332A (en) | 2003-07-31 |
AU762888B2 (en) | 2003-07-10 |
ATE273381T1 (en) | 2004-08-15 |
US20110210272A1 (en) | 2011-09-01 |
IL131332A0 (en) | 2001-01-28 |
CA2281205A1 (en) | 1998-08-13 |
US9745625B2 (en) | 2017-08-29 |
IL156002A0 (en) | 2003-12-23 |
US20020119455A1 (en) | 2002-08-29 |
EP1009802B1 (en) | 2004-08-11 |
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