WO1998015320A1

WO1998015320A1 - Reduction of organic matter

Info

Publication number: WO1998015320A1
Application number: PCT/US1997/018064
Authority: WO
Inventors: Eugene Mische
Original assignee: Eugene Mische
Priority date: 1996-10-08
Filing date: 1997-10-07
Publication date: 1998-04-16
Also published as: AU4747897A

Abstract

A method and specific agent is indicated for reduction and elimination of undesirable intra-organic structures (i.e. arteriosclerotic plaque) using the specific action of positron radiation on the binding and orbital electrons of the undesired mass. The anti-particle - particle annihilation phenomenom will reduce the mass to a significant degree, resulting in the liberation of light and heat radiation and an overall desirable loss of cohesiveness with regards to the undesired mass. This is a completely different means of using radio-isotopes than the usual ballistic billiard ball approach of alpha, beta and gamma rays. Also the ability to incrementally remove layers of debris by varying an adjunct sheath with calculated degrees of opacity to radiation will provide an amelioration of the restenotic conditions caused by more invasive means by reducing smooth muscle cell proliferation.

Description

REDUCTION OF ORGANIC MATTER

This invention relates to devices and methods for reduction and elimination of undesirable organic matter present in the human body. In addition the precision and means of action of the intervention is intended to ameliorate restenotic conditions.

Herein is proposed a very specific type of radiation which exhibits a very specific and well defined behavior. Namely radiation composed of positrons is used, this radiation exhibits peculiar annihilation ionization upon communication with its anti-particle ( here we are concerned with the binding, valence or orbital electrons connecting the molecules of the undesired mass together.

Prior art consists of the common collision type radiation where mass is not converted into heat and light as it is with positron interaction, but rather ionization occurs through an ill-defined billiard ball effect. The specifics of prior suggestions to use alpha, beta and gamma rays have many haphazard and unwanted effects due to the wide range of actions of the rays through tissue due to a constantly changing LET ( Linear Energy Transfer ) .

Positronic radiation can be fine tuned with sheathing proposed herein and the phenomena of mass deletion can be most effectively utilized.

The positron emitting material itself could be considered as any proton rich radioisotope such as Sodium-22, Cobalt-58 and Germanium-68. We also encourage the use of possible positron fed accelerators and accompanying peripherals.

The depth of annihilation interaction would be controlled with cover slleeves or sheaths which would use materials of calculated opacity to radiation, in particular positron rays.

We want to clarify that mere disruption of the tissue is not the goal, but rather a reduction in mass by the conversion of the embedded binding electrons of the undesired mass present in the fiduciary matter to dissipatable heat and light energy. The precision of the positron "surgery" in conjunction with the variable opacity sheath will reduce mass and provide a cleaner seperation of, say, arteriosclerotic plaque from arterial walls resulting in a reduction of smooth muscle cell proliferation and an ameliorating of possible restenotic conditions.

The method of presentation to the undesired matter may be through a stent, catheter driven baloon or device, fluid as in intravenous or concievably through an artifact connected to a positron accelerator .

Figure 1 shows 3 bound molecules of undesirable matter ( A=nucleus, E=Binding electron, P=Positron radiation)

Figure 2 shows that the interaction of the electron E and its anti-particle , the positron P has resulted in the conversion of masses E and P to radiant light and heat I.

Figure 3 shows the 3 molecules now unbound and dissassociated and ready for removal from the site of concern.

Figure 4 shows R as a positron emitting device with S as a sheath of chosen opacity to radiation to provide a more precise region or depth of interation between the positron radiation and the surrounding matter. Also noted in Fig. 4 are that the sheaths may be created in particular geometries unique to addressing the idividual characteristics of the undesired mass.

Claims

What is claimed is;

1) A device that that is placed within an organic structure (i.e. artery ) that has a composition partly comprised of positron emitting materials so as to expose a bodily site to the positron rays for the purpose of reducing and eliminating undesired mass at the chosen site ( i.e. arteriosclerotic plaque), by means of the antiparticle-particle ( positron-binding electron ) annihilation reaction.

2) A device as in 1 ) which may be stent-like.

3) A device as in 1) which may be catheter driven.

4) A device as in 1 ) which may be a angioplatic balloon.

5) A device as in 1) which may be an extension of an accelerator

6) A device as in 1 ) which is used intr-arterially .

7) A device as in \ ) which may be used intra-muscularly .

8) A device as in 1) which may be used in any organ of the body.

9) A device as in 1 ) which may be used in or on bone matter.

10)A sheath of varying opacity to radiation to be placed on or over any of the devices above in order to provide precision in removing the undesired tissue, or matter.

11) Sheaths as in 10) of particular desigh to match the unique features of the undesired mass.

12) A method of ameliorating restenotic conditions by selective removal of undesired mass and reducing the proliferation of smooth muscle cells by incorporating 1) with 10)

13) .An enhancement of 12) by the release of theraputic heat on the affected tissues resulting from the anti-particle-particle annihilation reaction.