WO1997037041A3 - Dna sequencing by mass spectrometry - Google Patents
Dna sequencing by mass spectrometry Download PDFInfo
- Publication number
- WO1997037041A3 WO1997037041A3 PCT/US1997/004394 US9704394W WO9737041A3 WO 1997037041 A3 WO1997037041 A3 WO 1997037041A3 US 9704394 W US9704394 W US 9704394W WO 9737041 A3 WO9737041 A3 WO 9737041A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- mass spectrometry
- chain
- mass
- nucleoside triphosphates
- dna sequencing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6872—Methods for sequencing involving mass spectrometry
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU22175/97A AU2217597A (en) | 1996-03-18 | 1997-03-18 | Dna sequencing by mass spectrometry |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/617,010 US6194144B1 (en) | 1993-01-07 | 1996-03-18 | DNA sequencing by mass spectrometry |
US08/617,010 | 1996-03-18 | ||
US54783596A | 1996-08-20 | 1996-08-20 | |
US5/547,835 | 1996-08-20 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO1997037041A2 WO1997037041A2 (en) | 1997-10-09 |
WO1997037041A3 true WO1997037041A3 (en) | 1997-12-04 |
WO1997037041A9 WO1997037041A9 (en) | 1997-12-31 |
Family
ID=27068672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/004394 WO1997037041A2 (en) | 1996-03-18 | 1997-03-18 | Dna sequencing by mass spectrometry |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2217597A (en) |
WO (1) | WO1997037041A2 (en) |
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US9249456B2 (en) | 2004-03-26 | 2016-02-02 | Agena Bioscience, Inc. | Base specific cleavage of methylation-specific amplification products in combination with mass analysis |
US9394565B2 (en) | 2003-09-05 | 2016-07-19 | Agena Bioscience, Inc. | Allele-specific sequence variation analysis |
US9540689B2 (en) | 1998-05-01 | 2017-01-10 | Life Technologies Corporation | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994016101A2 (en) * | 1993-01-07 | 1994-07-21 | Koester Hubert | Dna sequencing by mass spectrometry |
WO1994021822A1 (en) * | 1993-03-19 | 1994-09-29 | Sequenom, Inc. | Dna sequencing by mass spectrometry via exonuclease degradation |
WO1995014108A1 (en) * | 1993-11-17 | 1995-05-26 | Amersham International Plc | Primer extension mass spectroscopy nucleic acid sequencing method |
-
1997
- 1997-03-18 AU AU22175/97A patent/AU2217597A/en not_active Abandoned
- 1997-03-18 WO PCT/US1997/004394 patent/WO1997037041A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994016101A2 (en) * | 1993-01-07 | 1994-07-21 | Koester Hubert | Dna sequencing by mass spectrometry |
WO1994021822A1 (en) * | 1993-03-19 | 1994-09-29 | Sequenom, Inc. | Dna sequencing by mass spectrometry via exonuclease degradation |
WO1995014108A1 (en) * | 1993-11-17 | 1995-05-26 | Amersham International Plc | Primer extension mass spectroscopy nucleic acid sequencing method |
Non-Patent Citations (3)
Title |
---|
KIRPEKAR, F ET AL: "7-deazapurine bases offer a higher stability in the analysis of DNA by matrix-assisted laser desorption/ionization mass spectrometry", RAPID COMMUN. MASS SPECT., vol. 9, 1995, pages 525 - 31, XP002041458 * |
NORDHOFF E ET AL: "Ion stability of nucleic acids in infrared matrix-assisted laser desorption/ionization mass specrtrmetry", NUCLEIC ACIDS RESEARCH, vol. 21, no. 15, 25 July 1993 (1993-07-25), pages 3347 - 57, XP000537440 * |
SCHNEIDER K ET AL: "Increased stability of nucleic acids containing 7-deaza-guanosine and 7-deaza-adenosine may enable rapid DNA sequencing by matrix-assisted laser desorption spectroscopy", NUCLEIC ACIDS RESEARCH, vol. 23, no. 9, 11 May 1995 (1995-05-11), pages 1570 - 75, XP000601668 * |
Cited By (8)
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USRE44693E1 (en) | 1996-11-06 | 2014-01-07 | Sequenom, Inc. | Beads bound to a solid support and to nucleic acids |
US9540689B2 (en) | 1998-05-01 | 2017-01-10 | Life Technologies Corporation | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
US8999266B2 (en) | 2000-10-30 | 2015-04-07 | Agena Bioscience, Inc. | Method and apparatus for delivery of submicroliter volumes onto a substrate |
US7820378B2 (en) | 2002-11-27 | 2010-10-26 | Sequenom, Inc. | Fragmentation-based methods and systems for sequence variation detection and discovery |
US9394565B2 (en) | 2003-09-05 | 2016-07-19 | Agena Bioscience, Inc. | Allele-specific sequence variation analysis |
US9012144B2 (en) | 2003-11-12 | 2015-04-21 | Fluidigm Corporation | Short cycle methods for sequencing polynucleotides |
US9249456B2 (en) | 2004-03-26 | 2016-02-02 | Agena Bioscience, Inc. | Base specific cleavage of methylation-specific amplification products in combination with mass analysis |
US8962247B2 (en) | 2008-09-16 | 2015-02-24 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses |
Also Published As
Publication number | Publication date |
---|---|
AU2217597A (en) | 1997-10-22 |
WO1997037041A2 (en) | 1997-10-09 |
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