WO1995028196A1 - A dilation-drug delivery catheter - Google Patents
A dilation-drug delivery catheter Download PDFInfo
- Publication number
- WO1995028196A1 WO1995028196A1 PCT/IB1995/000052 IB9500052W WO9528196A1 WO 1995028196 A1 WO1995028196 A1 WO 1995028196A1 IB 9500052 W IB9500052 W IB 9500052W WO 9528196 A1 WO9528196 A1 WO 9528196A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drug delivery
- dilation
- catheter
- lumen
- catheter shaft
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/104—Balloon catheters used for angioplasty
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M2025/0175—Introducing, guiding, advancing, emplacing or holding catheters having telescopic features, interengaging nestable members movable in relations to one another
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1011—Multiple balloon catheters
- A61M2025/1015—Multiple balloon catheters having two or more independently movable balloons where the distance between the balloons can be adjusted, e.g. two balloon catheters concentric to each other forming an adjustable multiple balloon catheter system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1079—Balloon catheters with special features or adapted for special applications having radio-opaque markers in the region of the balloon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1006—Balloons formed between concentric tubes
Definitions
- a DILATION-DRUG DELIVERY CATHETER FIELD OF THE INVENTION A dilation-drug delivery catheter, and, more particularly, a dilation-drug delivery catheter comprising a drug delivery portion within a dilation portion, wherein the dilation portion can be retracted after dilation, revealing the drug delivery portion.
- antithrombolytic agents such as heparin may prevent clotting.
- Antiproliferative agents such as dexamethasone, can prevent smooth muscle cell migration and proliferation.
- a catheter having a thin walled flexible balloon with a plurality of small holes.
- angioplastic procedure such a balloon can be advanced to the dilation site and inflated with heparin, or some other medication.
- the medication exits the inflated balloon, which is in contact with the arterial wall, through the holes.
- Such "weeping" balloons may damage the arterial wall, however.
- having to insert a second catheter for drug delivery after removal of the dilation catheter is cumbersome and time consuming. It can also be difficult to precisely locate the dilation site after the dilation catheter is removed.
- U.S. Patent Nos. 4,824,436 and 4,636,195 also to Wolinsky, disclose a catheter with a dilation balloon and a pair of occlusion balloons proximal and distal to the dilation balloon.
- a drug delivery conduit is provided between the distal occlusion balloon and the dilation balloon.
- the dilation balloon is deflated, the occlusion balloons are inflated and a drug is delivered. Because of the presence of the dilation balloon, there is only a small region available for drug delivery. Drug delivery may, therefore, be slow and of too low volume to be effective.
- the present invention provides a single catheter which can both dilate a stenosis and deliver an adequate supply of a desired drug directly to the dilation site.
- the dilation-drug delivery catheter of the present invention comprises a dilation portion including a dilation balloon attached to an outer catheter shaft .
- the outer catheter shaft comprises a dilation lumen for providing inflation fluid to the dilation balloon, and a central lumen.
- a drug delivery portion of the catheter is located at least in part within the central lumen.
- the drug delivery portion comprises an inner catheter shaft having at least one drug delivery port.
- the inner catheter shaft defines a drug delivery lumen, which provides any desired drug to the drug delivery port .
- the drug delivery port is typically located in a portion of the inner catheter shaft lying within the central lumen during dilation.
- the dilation portion of the catheter can be moved with respect to the drug delivery portion such that the dilation portion can be retracted from the distal end of the drug delivery portion after dilation, revealing the drug delivery port .
- the drug delivery portion of the catheter of the present invention preferably further comprises a first occlusion balloon distal to the drug delivery port and an inflation lumen in fluid communication with the first occlusion balloon.
- a second occlusion balloon is preferably provided proximal to the drug delivery port .
- the occlusion balloons maintain the delivered drug in proximity with the dilation site.
- the same inflation lumen can be in fluid communication with the first and second balloons.
- a plurality of drug delivery ports are preferably provided, as are perfusion means for allowing blood to flow through the dilation-drug delivery catheter, beyond the occlusion balloon.
- a dilation-drug delivery catheter comprises a dilation portion comprising a dilation balloon and a drug delivery portion having a distal end, wherein the portions can be moved with respect to each other.
- the catheter has a dilation position, wherein the distal end of the drug delivery portion is located at least in part within the dilation portion, and a drug delivery position, wherein the dilation portion is retracted to reveal the distal end of the drug delivery portion.
- a dilation-drug delivery catheter comprises a dilation balloon bonded to an outer catheter shaft.
- the catheter shaft has an outer wall and an inner wall defining a lumen for providing dilation fluid to the dilation balloon.
- the inner wall further defines a central lumen.
- An inner catheter shaft comprises a pair of occlusion balloons at its distal end, a lumen in fluid communication with the occlusion balloons to provide inflation fluid to the occlusion balloons, a plurality of drug delivery ports between the occlusion balloons, a lumen in fluid communication with the drug delivery ports to provide drugs to the ports, and a guide wire lumen.
- a portion of the inner catheter shaft lies within the central lumen, and the outer catheter shaft can be moved with respect to the inner catheter shaft to reveal the occlusion balloons and drug delivery ports.
- the drug delivery ports lie within the central lumen prior to the outer catheter shaft being retracted.
- FIG. 1 is a view of a dilation-drug delivery catheter in accordance with the present invention, wherein the distal portion of the catheter is shown enlarged and in cross-section, in the dilation position of the catheter;
- FIG. 2 is a cross-sectional view of the distal portion of the catheter of FIG. 1, wherein a dilation balloon is shown inflated;
- FIG. 3 is a cross-sectional view of the distal portion of the catheter of FIG. 1, along line AA of FIG. 1;
- FIG. 4 is a cross-sectional view of the distal portion of the catheter of FIG. 1, with its dilation portion retracted, showing the drug delivery position of the catheter;
- FIG. 5 is a side view of the distal portion of the catheter of FIG. 1, wherein two occlusion balloons are inflated.
- FIG. 1 is a view of a dilation-drug delivery catheter 10 in accordance with the present invention, wherein the distal portion of the catheter 10 is shown enlarged and in cross-section.
- the dilation- drug delivery catheter 10 comprises a dilation portion 20 and a drug delivery portion 50.
- the dilation portion 20 comprises a dilation balloon 24 bonded to an outer catheter shaft 22 at sites 26 and 28.
- the catheter 10 is shown in its dilation position.
- the dilation balloon 24 is deflated
- FIG. 2 a cross-sectional view of the distal portion of the dilation-drug delivery catheter 10 of FIG. 1, the dilation balloon 24 is shown inflated.
- the outer catheter shaft 22 has an outer wall 34 and an inner wall 36 which define a dilation lumen 38 for providing dilation fluid to the dilation balloon 22.
- the inner wall 36 also defines a central lumen 40 for receiving the drug delivery portion 50.
- FIG. 3 is a cross-sectional view of the dilation-drug delivery catheter 10, through line A-A of FIG. 1, showing the outer wall 34, inner wall 36, the dilation lumen 38 and the central lumen 40.
- the drug delivery portion 50 of the catheter 10 comprises an inner catheter shaft 52, whose distal end is located at least in part within the second lumen 40.
- the inner catheter shaft 52 includes a drug delivery lumen 54, which communicates with the exterior of the shaft 52 through drug delivery ports 56.
- Three drug delivery ports 56 are provided in this embodiment. A plurality of such ports are preferably provided to ensure the delivery of adequate drug to the dilation site.
- the drug delivery ports 56 preferably lie within the central lumen 40 during dilation.
- FIG. 3 shows that the drug delivery lumen 54 is preferably semi-circular.
- a distal occlusion balloon 58 and a proximal occlusion balloon 60 are preferably provided to isolate the dilation site during drug delivery.
- the occlusion balloons 58, 60 are shown inflated in the side view of Fig. 5.
- the occlusion balloons 58, 60 maintain the drug in proximity with the portion of the arterial wall which has been dilated, improving the absorption and efficacy of the drug.
- An inflation lumen 62 in the inner catheter shaft 52 is provided to convey inflation fluid to the occlusion balloons 58, 60.
- the inner catheter shaft 52 also typically includes a guide wire lumen 64.
- the inflation lumen 62 and guide wire lumen 64 are shown in cross-section in Fig. 3.
- the inflation lumen 62 is also preferably semi-circular and in the same radial plane as the drug delivery lumen 54. To deliver an adequate amount of drug in the time allowed, the drug delivery lumen 54 will generally need to be larger than the inflation lumen 62.
- the portion of the inner catheter shaft 52 including the distal occlusion balloon 58 extends beyond the distal tip of the dilation portion 20 while the catheter is in its dilation position.
- the distal occlusion balloon 58 can lie within the second lumen 40 in the dilation position, as well.
- FIGS. 4 and 5 the dilation-drug delivery catheter 10 of the present invention is shown in its drug delivery position.
- the dilation portion 20 is shown retracted to fully reveal the distal end of the drug delivery portion 50 of the catheter 10, which comprises the occlusion balloons 58, 60, and the drug delivery ports 56.
- FIG. 5 is a side view of the catheter 10, showing the occlusion balloons 58, 60, inflated as they would be immediately prior to and during drug delivery.
- the present invention enables a plurality of drug delivery ports 56 to be provided between the occlusion balloons 58, 60, better ensuring the delivery of an adequate quantity of drug.
- Perfusion openings 88 are preferably provided through the walls of the inner catheter shaft 52 to the guide wire lumen 64 as shown in FIG.
- the proximal end of the catheter 10 includes a Y-adaptor 68 including a port 66, as is known in the art.
- a tube (not shown) is connected to the dilation lumen 38 of the outer catheter shaft 22 and extends through the port 66.
- the outer catheter shaft ends within the Y-adaptor 68, proximate the base of the port 66.
- a syringe can be used to supply the dilation fluid through the port 66 into the dilation lumen 38, also as is known in the art.
- a Tuohy-Borst adapter 70 is threaded on the central port of the Y-adaptor 68.
- the inner catheter shaft 52 extends through the Y-adaptor 68 and Tuohy- Borst adapter 70.
- three tubes 72, 74, and 76 are connected to the drug delivery lumen 54, inflation lumen 62 and guide wire lumen 64, respectively, of the inner catheter shaft 52.
- Hubs 78 are connected to each tube.
- the guide wire can be inserted into the guide wire lumen 64, through tube 76.
- Syringes can also be used to supply inflation fluid for the occlusion balloons 58, 60 and any desired drug through tubes 74 and 72, respectively.
- the outer diameter of the catheter 10 and the deflated dilation balloon 24 is preferably no greater than about 0.042-0.050 inches, so that it can be used with a 7 or 8 French guiding catheter.
- the portion of the inner catheter shaft 52 which extends out of the Tuohy-Borst adapter 68 flares to an outer diameter of about 0.200 inches at about point 80.
- the tubes 72, 74, 76 are held together by a heat shrink tubing 82.
- the distal end 84 of the inner catheter shaft 52 preferably includes a resilient tip 96 which comprises a material softer than that of the inner catheter shaft 22.
- the tip 96 spreads or bends when it contacts body tissue, easing the catheter's passage through the vascular system and helping to avoid tissue damage.
- the tip 96 can be made of ultra low density polyethylene 4603 from Dow Chemical Corporation, which has a melt flow rate at 190°C (ASTM D-1238) of 0.7-0.9 g/10 min. and a density (ASTM D-792) of 0.9030-0.9070 g/cc.
- the tip 96 can also be a nylon, such as PEBA 25D from Elf Atochem GmbH, which has an ultimate tensile strength (ASTM D-638) of 4950 psi min., an ultimate elongation (ASTM-638) of 640% min., a flexural modulus (ASTM D-790) of 2100 psi min., a Durometer (ASTM D-2240) of 25D ⁇ 4D, and a melting point (ASTM D-3418) of 142°-153°C.
- the tip 96 can be connected to the inner catheter shaft 22 by an adhesive or therma1 bonding.
- Radiopaque markers 86 of gold or tantalum are also preferably provided on the inner catheter shaft 52 within the occlusion balloons 58, 60, and on the outer catheter shaft 22 within the dilation balloon 24, as shown, to assist in monitoring the position of the catheter on a fluoroscope during a PTA or PTCA procedure, as is known in the art.
- the inner catheter shaft 52 and occlusion balloons 58, 60 are preferably coated with a lubricous material, such as silicone, acrylimide, or a hydrophilic polyurethane coating, to ease retraction of the dilation portion 20 after dilation.
- the outer catheter shaft 22 and dilation balloon 24 can be similarly coated to ease its advance through a guiding catheter and a lesion, as is known in the art.
- the inner and outer catheter shafts can be of any material suitable for catheters, such as linear low density or high density polyethylene, nylon, polyurethane, polypropylene, silicone rubber, or other non-thrombogenic materials.
- a linear low density polyethylene which can be used for the outer catheter shaft 22 is Dowlex 2038 from Dow Chemical Company, which has a melt flow rate at 190°C (ASTM D- 1238) of 0.85-1.15 g/10 min. and a density (ASTM D- 792) of 0.9330-0.9370 g/cc.
- a high density polyethylene which can be used for the outer catheter shaft 22 is LB 8320-00 from Quantum Chemical
- melt flow rate at 190°C (ASTM D-1238) of 0.20-0.36 g/10 min. and a density (D-1505) of 0.9566 g/cc min.
- a nylon which can be used for the inner or outer catheter shafts 22, 52 is nylon 12, such as L2101F
- a high density polyethylene which can be used for the inner catheter shaft 52 is LM6007 from Quantum Chemical Corporation, which has the following characteristics:
- the outer catheter shaft 22 and inner catheter shaft 52 are extruded separately.
- a bump extrusion process can be used, as is known in the art.
- the tubes 72, 74 and 76 are inserted into the shaft's wider portion and thermally bonded in place.
- An adhesive can be used, as well.
- a tube (not shown) is inserted and similarly bonded to the dilation lumen 38 of the outer catheter shaft 22. That tube extends through the port 66 of the Tuohy-Borst adaptor 70.
- the perfusion openings 88 and drug delivery ports 56 are made.
- the dilation balloon 24 can be of any type and size appropriate for PTA and PTCA procedures.
- the balloon 22 can be of polyethylene, polyethylene terephthalate, nylon, polyurethane, or any other material suitable for a dilation balloon.
- the balloon 24 can be compliant, non-compliant, or semi-compliant.
- the dilation balloon 24 can be attached to the outer catheter shaft 22 through thermal bonding, including laser bonding or ultrasonic bonding, or with an adhesive, as is known in the art.
- U.S. Patent No. 5,267,959 An apparatus and process for laser bonding angioplasty balloon catheters is disclosed in U.S. Patent No. 5,267,959, which was filed on November 29, 1991 by the inventor of the present invention and is assigned to the assignee of the present invention.
- U.S. Patent No. 5,267,959 is incorporated by reference herein.
- the balloon 22 is preferably of the same or compatible material as the catheter shaft 28, to enable thermal bonding.
- a low density polyethylene which can be used for the dilation balloon 24 is P.E.
- a linear low density polyethylene which can be used is Dowlex 2247A LLPDE from Dow Chemical Corporation, which has a melt index at 190°C/2.16kg (ASTM D-1238) of 2.0-2.6 g/10 min., a density (ASTM D-1505) of 0.9150-0.9190 • g/cc, and a melt point (D-3417, D-3418 (REF)) of 122- 125°C.
- the occlusion balloons 58, 60 can be nylon, polyamide copoly er, polyethylene, polyethylene terephthalate, polyurethane, Kraton, silicone, latex or any other soft, non-thrombogenic material which will seal against, but not expand, the arterial wall when inflated.
- the balloons can be tubes which expand on inflation or blow molded balloons. If the balloon material is compatible with the inner catheter shaft 52, the occlusion balloons 58, 60 can be attached by the thermal bonding techniques discussed above. If not, an adhesive may be used.
- a nylon which can be used for the occlusion balloons 58, 60 is L25 G Grilamid from EMS-Chemie AG, which has a melting point of 178°C, a density (DIN 53479) of 1.01 Kg/dm 3 , a tensile strength (DIN 53455) of 40 N/mm 2 , an elongation at yield (DIN 53455) of 10% and a Shore D hardness (DIN 53505) of 72.
- the dilation-drug delivery catheter 10 of the present invention can be introduced into the vascular system and advanced to the site of the stenosis by a guiding catheter, as would an ordinary dilation catheter.
- a guide wire is advanced through the stenosis
- the catheter 10 is advanced from the guiding catheter, over the guide wire, through the stenosis.
- Dilation fluid is injected with a syringe -14- through the port 66 of the Y-adaptor 68, to the dilation lumen 38, to dilate the balloon 24 as shown in FIG. 2, opening the stenosis, as would an ordinary dilation catheter.
- the dilation balloon 24 is deflated and the dilation portion 20 of the catheter 10 is retracted far enough to reveal the drug delivery ports 56, the proximal occlusion balloon 60 and the perfusion openings 68, if present, putting the catheter into the drug delivery position of FIG. 3.
- the dilation portion can be retracted by loosening the Tuohy-Borst adaptor 70 and withdrawing the outer catheter 22 a suitable distance. After the dilation portion 20 is retracted, the Tuohy-Borst adapter is tightened.
- the guide wire is also preferably retracted to a position proximal to the perfusion openings 88 to allow blood to flow through the inner catheter shaft 52. If active perfusion is required, the guide wire can be completely removed and blood or perfluorochemicals such as Fluosol ® can be injected with a syringe through tube 76, as is known in the art.
- Inflation fluid is then injected with a syringe through the tube 74 to inflate the distal and proximal occlusion balloons 58, 60, until the occlusion balloons meet and seal the arterial wall, isolating the dilated region.
- Antithrombolytic, antiproliferative, or any other type of drug can now be injected through tube 72, drug delivery lumen 54 and drug delivery ports 56, via a syringe, to the dilation site.
- the occlusion balloons are deflated and the dilation-drug delivery catheter 10 is withdrawn from the blood vessel.
- One drug formulation which may be promising is dexamethasone absorbed in poly-lactic/poly-glycolic particles with diameters substantially less than 100 microns. Such particles can adhere to or penetrate the arterial wall. The surface of the particles can be treated with cell adhesion proteins and peptides based peptides to improve the adhesion of the particles with the arterial wall.
- An arginine glycine aspartic acid based peptide which can be used is Teptite 2000 ® from Telios Pharmaceuticals, Inc.
- the dilation-drug delivery catheter of the present invention provides a single catheter which can perform dual functions, saving time and enabling delivery of drug directly to the dilation site.
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7526828A JP2930422B2 (en) | 1994-04-13 | 1995-01-23 | Expandable drug delivery catheter |
CA002186493A CA2186493C (en) | 1994-04-13 | 1995-01-23 | A dilation-drug delivery catheter |
EP95905222A EP0755279A1 (en) | 1994-04-13 | 1995-01-23 | A dilation-drug delivery catheter |
AU13914/95A AU699000B2 (en) | 1994-04-13 | 1995-01-23 | A dilation-drug delivery catheter |
MXPA/A/1996/004820A MXPA96004820A (en) | 1994-04-13 | 1996-10-11 | A catheter for the release of farmaco pordilatac |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/227,254 | 1994-04-13 | ||
US08/227,254 US5415636A (en) | 1994-04-13 | 1994-04-13 | Dilation-drug delivery catheter |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1995028196A1 true WO1995028196A1 (en) | 1995-10-26 |
Family
ID=22852390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB1995/000052 WO1995028196A1 (en) | 1994-04-13 | 1995-01-23 | A dilation-drug delivery catheter |
Country Status (6)
Country | Link |
---|---|
US (2) | US5415636A (en) |
EP (1) | EP0755279A1 (en) |
JP (1) | JP2930422B2 (en) |
AU (1) | AU699000B2 (en) |
CA (1) | CA2186493C (en) |
WO (1) | WO1995028196A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9622890B2 (en) | 2012-04-27 | 2017-04-18 | Terumo Kabushiki Kaisha | Catheter for forming biological tissue holding member |
US11602618B2 (en) | 2016-06-01 | 2023-03-14 | Hexacath | Device forming an infusion catheter for treating at least one partial or total obstruction in a passage, such as a body passage |
Families Citing this family (151)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4191989A (en) * | 1988-08-24 | 1990-03-23 | Marvin J. Slepian | Biodegradable polymeric endoluminal sealing |
US5591129A (en) * | 1994-03-02 | 1997-01-07 | Scimed Life Systems, Inc. | Perfusion balloon angioplasty catheter |
WO1995028983A1 (en) * | 1994-04-20 | 1995-11-02 | Solar Ronald J | Active perfusion dilatation catheter |
US5810767A (en) * | 1994-05-11 | 1998-09-22 | Localmed, Inc. | Method and apparatus for pressurized intraluminal drug delivery |
JPH10503673A (en) * | 1994-06-24 | 1998-04-07 | アドバンスト・カーディオバスキュラー・システムズ・インコーポレイテッド | Catheter with reusable proximal body |
US5558652A (en) * | 1994-10-06 | 1996-09-24 | B. Braun Medical, Inc. | Introducer with radiopaque marked tip and method of manufacture therefor |
US5702372A (en) | 1995-02-08 | 1997-12-30 | Medtronic, Inc. | Lined infusion catheter |
US6176842B1 (en) * | 1995-03-08 | 2001-01-23 | Ekos Corporation | Ultrasound assembly for use with light activated drugs |
US6210356B1 (en) * | 1998-08-05 | 2001-04-03 | Ekos Corporation | Ultrasound assembly for use with a catheter |
US5674198A (en) * | 1995-06-23 | 1997-10-07 | Cordis Corporation | Tandem balloon catheter |
US5752934A (en) * | 1995-09-18 | 1998-05-19 | W. L. Gore & Associates, Inc. | Balloon catheter device |
US20060271091A1 (en) * | 1995-09-18 | 2006-11-30 | Campbell Carey V | Balloon catheter device |
US5868704A (en) * | 1995-09-18 | 1999-02-09 | W. L. Gore & Associates, Inc. | Balloon catheter device |
US6440097B1 (en) | 1995-10-06 | 2002-08-27 | Target Therapeutics, Inc. | Balloon catheter with delivery side holes |
EP0955933B1 (en) * | 1995-10-13 | 2009-08-26 | Medtronic Vascular, Inc. | A device for interstitial transvascular intervention |
US6283951B1 (en) * | 1996-10-11 | 2001-09-04 | Transvascular, Inc. | Systems and methods for delivering drugs to selected locations within the body |
US6113567A (en) * | 1995-10-25 | 2000-09-05 | Becker; Bruce B. | Lacrimal silicone tube with reduced friction |
US5843104A (en) * | 1995-11-21 | 1998-12-01 | Samuels; Peter B. | Method of removing blood vessels from the human body |
US5882334A (en) * | 1995-12-04 | 1999-03-16 | Target Therapeutics, Inc. | Balloon/delivery catheter assembly with adjustable balloon positioning |
US5823996A (en) * | 1996-02-29 | 1998-10-20 | Cordis Corporation | Infusion balloon catheter |
WO1997038631A1 (en) * | 1996-04-18 | 1997-10-23 | Applied Medical Resources Corporation | Remote clot management |
US6544276B1 (en) * | 1996-05-20 | 2003-04-08 | Medtronic Ave. Inc. | Exchange method for emboli containment |
US6270477B1 (en) * | 1996-05-20 | 2001-08-07 | Percusurge, Inc. | Catheter for emboli containment |
US6652480B1 (en) | 1997-03-06 | 2003-11-25 | Medtronic Ave., Inc. | Methods for reducing distal embolization |
US20010049517A1 (en) | 1997-03-06 | 2001-12-06 | Gholam-Reza Zadno-Azizi | Method for containing and removing occlusions in the carotid arteries |
US6022336A (en) | 1996-05-20 | 2000-02-08 | Percusurge, Inc. | Catheter system for emboli containment |
US6152909A (en) * | 1996-05-20 | 2000-11-28 | Percusurge, Inc. | Aspiration system and method |
US20070161968A1 (en) * | 1996-06-04 | 2007-07-12 | Vance Products Inc., Dba Cood Urological Inc. | Implantable medical device with pharmacologically active ingredient |
EP0835673A3 (en) * | 1996-10-10 | 1998-09-23 | Schneider (Usa) Inc. | Catheter for tissue dilatation and drug delivery |
US6193685B1 (en) * | 1996-11-26 | 2001-02-27 | Schneider (Usa) Inc. | Perfusion catheter |
AU5383998A (en) * | 1996-12-13 | 1998-07-03 | Data Sciences International, Inc. | Biocompatible medical devices with polyurethane surface |
DK0959935T3 (en) * | 1997-02-04 | 2008-05-13 | Cook Urological Inc | Suprapubic drainage catheter |
US6010449A (en) * | 1997-02-28 | 2000-01-04 | Lumend, Inc. | Intravascular catheter system for treating a vascular occlusion |
US6217549B1 (en) | 1997-02-28 | 2001-04-17 | Lumend, Inc. | Methods and apparatus for treating vascular occlusions |
US5968064A (en) * | 1997-02-28 | 1999-10-19 | Lumend, Inc. | Catheter system for treating a vascular occlusion |
US6508825B1 (en) | 1997-02-28 | 2003-01-21 | Lumend, Inc. | Apparatus for treating vascular occlusions |
US6120516A (en) * | 1997-02-28 | 2000-09-19 | Lumend, Inc. | Method for treating vascular occlusion |
US6849068B1 (en) | 1997-03-06 | 2005-02-01 | Medtronic Ave, Inc. | Aspiration catheter |
AU6688398A (en) * | 1997-03-06 | 1998-09-22 | Percusurge, Inc. | Intravascular aspiration system |
US6136007A (en) * | 1997-04-17 | 2000-10-24 | St. Jude Medical Cardiovascular Group, Inc, | Apparatus for handling tubing used in medical procedures |
JPH10290837A (en) * | 1997-04-18 | 1998-11-04 | Kanegafuchi Chem Ind Co Ltd | Balloon catheter and manufacture of multi-lumen shaft used therefor |
US6723063B1 (en) * | 1998-06-29 | 2004-04-20 | Ekos Corporation | Sheath for use with an ultrasound element |
US6582392B1 (en) | 1998-05-01 | 2003-06-24 | Ekos Corporation | Ultrasound assembly for use with a catheter |
US6676626B1 (en) | 1998-05-01 | 2004-01-13 | Ekos Corporation | Ultrasound assembly with increased efficacy |
EP0893138B1 (en) * | 1997-06-23 | 2004-05-26 | Schneider (Europe) GmbH | Catheter assembly |
DE19732965A1 (en) * | 1997-07-31 | 1999-02-18 | Knoerig Joachim Michael Dr | Balloon catheter |
US6090069A (en) * | 1997-08-05 | 2000-07-18 | Walker; Frank J. | Irrigation and drainage urinary catheter |
US6056721A (en) * | 1997-08-08 | 2000-05-02 | Sunscope International, Inc. | Balloon catheter and method |
US6217527B1 (en) * | 1998-09-30 | 2001-04-17 | Lumend, Inc. | Methods and apparatus for crossing vascular occlusions |
US6398798B2 (en) | 1998-02-28 | 2002-06-04 | Lumend, Inc. | Catheter system for treating a vascular occlusion |
US6179813B1 (en) * | 1998-04-24 | 2001-01-30 | Scimed Life Systems, Inc. | Vascular infusion device |
US6148222A (en) * | 1998-07-10 | 2000-11-14 | Cardiocommand, Inc. | Esophageal catheters and method of use |
US6210365B1 (en) * | 1998-08-14 | 2001-04-03 | Cardiovention, Inc. | Perfusion catheter system having sutureless arteriotomy seal and methods of use |
US7637886B2 (en) * | 1999-01-25 | 2009-12-29 | Atrium Medical Corporation | Expandable fluoropolymer device and method of making |
US6955661B1 (en) * | 1999-01-25 | 2005-10-18 | Atrium Medical Corporation | Expandable fluoropolymer device for delivery of therapeutic agents and method of making |
US6395208B1 (en) | 1999-01-25 | 2002-05-28 | Atrium Medical Corporation | Method of making an expandable fluoropolymer device |
US6709427B1 (en) * | 1999-08-05 | 2004-03-23 | Kensey Nash Corporation | Systems and methods for delivering agents into targeted tissue of a living being |
US7892201B1 (en) | 1999-08-27 | 2011-02-22 | Gore Enterprise Holdings, Inc. | Balloon catheter and method of mounting same |
US6592567B1 (en) * | 1999-12-07 | 2003-07-15 | Chf Solutions, Inc. | Kidney perfusion catheter |
US8172783B1 (en) | 1999-12-30 | 2012-05-08 | Advanced Cardiovascular Systems, Inc | Conduit system for isolation of fluids in biological tissues |
US6685672B1 (en) | 2000-07-13 | 2004-02-03 | Edwards Lifesciences Corporation | Multi-balloon drug delivery catheter for angiogenesis |
LU90613B1 (en) * | 2000-07-24 | 2002-01-25 | Crash Holding S A | Intra-and peri-articular catheter |
US6464662B1 (en) * | 2000-07-26 | 2002-10-15 | Image-Guided Neurologics, Inc. | Drug delivery and catheter systems, apparatus and processes |
US6572579B1 (en) | 2000-09-13 | 2003-06-03 | Image-Guided Neurologics, Inc. | Drug delivery and catheter systems, apparatus and processes |
US20020058961A1 (en) * | 2000-10-16 | 2002-05-16 | Aguilar Amiel R. | Catheter |
US20020091355A1 (en) * | 2000-11-17 | 2002-07-11 | Ascend Medical, Inc. | Compliant delivery catheter |
WO2002045598A2 (en) * | 2000-12-05 | 2002-06-13 | Lumend, Inc. | Catheter system for vascular re-entry from a sub-intimal space |
US6692458B2 (en) | 2000-12-19 | 2004-02-17 | Edwards Lifesciences Corporation | Intra-pericardial drug delivery device with multiple balloons and method for angiogenesis |
US6669662B1 (en) | 2000-12-27 | 2003-12-30 | Advanced Cardiovascular Systems, Inc. | Perfusion catheter |
US7481790B2 (en) * | 2000-12-27 | 2009-01-27 | Advanced Cardiovascular Systems, Inc. | Vessel enlargement by arteriogenic factor delivery |
US6964439B2 (en) * | 2001-01-11 | 2005-11-15 | Aisin Seiki Kabushiki Kaisha | Vehicle door handle device |
AU2002243987A1 (en) * | 2001-02-13 | 2002-08-28 | Lumend, Inc. | Method and apparatus for micro-dissection of vascular occlusions |
US6625486B2 (en) | 2001-04-11 | 2003-09-23 | Advanced Cardiovascular Systems, Inc. | Method and apparatus for intracellular delivery of an agent |
US6726674B2 (en) | 2001-09-04 | 2004-04-27 | Jomed Gmbh | Methods for minimally invasive, localized delivery of sclerotherapeutic agents |
AU2002359576A1 (en) | 2001-12-03 | 2003-06-17 | Ekos Corporation | Catheter with multiple ultrasound radiating members |
US7141044B2 (en) | 2001-12-11 | 2006-11-28 | Ekos Corporation | Alternate site gene therapy |
US8062251B2 (en) * | 2002-02-01 | 2011-11-22 | Vascular Designs, Inc. | Multi-function catheter and use thereof |
US20050267407A1 (en) * | 2002-02-01 | 2005-12-01 | Vascular Designs, Inc. | Multi-function catheter and use thereof |
JP4597526B2 (en) * | 2002-02-01 | 2010-12-15 | ロバート,ジェー. ゴールドマン | Multifunctional catheter and method of use thereof |
US8226629B1 (en) | 2002-04-01 | 2012-07-24 | Ekos Corporation | Ultrasonic catheter power control |
US6921371B2 (en) * | 2002-10-14 | 2005-07-26 | Ekos Corporation | Ultrasound radiating members for catheter |
US20060047261A1 (en) * | 2004-06-28 | 2006-03-02 | Shailendra Joshi | Intra-arterial catheter for drug delivery |
US7862575B2 (en) * | 2003-05-21 | 2011-01-04 | Yale University | Vascular ablation apparatus and method |
US20040236410A1 (en) * | 2003-05-22 | 2004-11-25 | Atrium Medical Corp. | Polymeric body formation |
US20040236278A1 (en) * | 2003-05-22 | 2004-11-25 | Atrium Medical Corp. | Therapeutic agent delivery |
US20040236279A1 (en) * | 2003-05-22 | 2004-11-25 | Atrium Medical Corp. | Gaseous therapeutic agent delivery |
CA2528959C (en) * | 2003-06-10 | 2011-12-20 | Lumend, Inc. | Catheter systems and methods for crossing vascular occlusions |
US20050004594A1 (en) * | 2003-07-02 | 2005-01-06 | Jeffrey Nool | Devices and methods for aspirating from filters |
US7736362B2 (en) * | 2003-09-15 | 2010-06-15 | Boston Scientific Scimed, Inc. | Catheter balloons |
US20050226991A1 (en) * | 2004-04-07 | 2005-10-13 | Hossainy Syed F | Methods for modifying balloon of a catheter assembly |
US20060111704A1 (en) * | 2004-11-22 | 2006-05-25 | Rox Medical, Inc. | Devices, systems, and methods for energy assisted arterio-venous fistula creation |
DK1951864T3 (en) | 2005-11-07 | 2014-07-28 | Amorcyte Inc | COMPOSITIONS AND PROCEDURES FOR VASCULAR INJURY REPAIR |
US8172792B2 (en) * | 2005-12-27 | 2012-05-08 | Tyco Healthcare Group Lp | Embolic protection systems for bifurcated conduits |
US8287503B2 (en) * | 2006-03-13 | 2012-10-16 | Applied Medical Resources Corporation | Balloon trocar |
US8147453B2 (en) | 2006-03-13 | 2012-04-03 | Applied Medical Resources Corporation | Balloon trocar |
US20080097300A1 (en) * | 2006-08-07 | 2008-04-24 | Sherif Eskaros | Catheter balloon with multiple micropleats |
US20080140173A1 (en) | 2006-08-07 | 2008-06-12 | Sherif Eskaros | Non-shortening wrapped balloon |
US7785290B2 (en) | 2006-08-07 | 2010-08-31 | Gore Enterprise Holdings, Inc. | Non-shortening high angle wrapped balloons |
US8460240B2 (en) * | 2006-08-07 | 2013-06-11 | W. L. Gore & Associates, Inc. | Inflatable toroidal-shaped balloons |
US20080125711A1 (en) | 2006-08-07 | 2008-05-29 | Alpini Alfred A | Catheter balloons with integrated non-distensible seals |
US20080097374A1 (en) * | 2006-08-07 | 2008-04-24 | Korleski Joseph E | Inflatable shaped balloons |
US9180279B2 (en) * | 2006-08-07 | 2015-11-10 | W. L. Gore & Associates, Inc. | Inflatable imbibed polymer devices |
WO2008033983A1 (en) | 2006-09-13 | 2008-03-20 | Vascular Insights Llc | Vascular treatment device |
US8147413B2 (en) * | 2006-10-12 | 2012-04-03 | Innoscion, Llc | Image guided catheter having deployable balloons and pericardial access procedure |
US8192363B2 (en) | 2006-10-27 | 2012-06-05 | Ekos Corporation | Catheter with multiple ultrasound radiating members |
ITMI20062333A1 (en) * | 2006-12-05 | 2008-06-06 | Mario Salerno | DEVICE TO ASSIST THE SCLORESANT TREATMENT OF VARICOSE VEINS |
US10182833B2 (en) | 2007-01-08 | 2019-01-22 | Ekos Corporation | Power parameters for ultrasonic catheter |
US8617205B2 (en) | 2007-02-01 | 2013-12-31 | Cook Medical Technologies Llc | Closure device |
WO2008094706A2 (en) * | 2007-02-01 | 2008-08-07 | Cook Incorporated | Closure device and method of closing a bodily opening |
ES2471118T3 (en) | 2007-06-22 | 2014-06-25 | Ekos Corporation | Method and apparatus for the treatment of intracranial hemorrhages |
US8292907B2 (en) * | 2007-08-31 | 2012-10-23 | Cook Medical Technologies Llc | Balloon assisted occlusion device |
WO2009079415A1 (en) * | 2007-12-14 | 2009-06-25 | Ekos Corporation | Ultrasound pulse shaping |
US8162879B2 (en) | 2008-09-22 | 2012-04-24 | Tyco Healthcare Group Lp | Double balloon catheter and methods for homogeneous drug delivery using the same |
WO2010039862A1 (en) * | 2008-09-30 | 2010-04-08 | Rox Medical, Inc. | Methods for screening and treating patients with compromised cardiopulmonary function |
US20100261662A1 (en) * | 2009-04-09 | 2010-10-14 | Endologix, Inc. | Utilization of mural thrombus for local drug delivery into vascular tissue |
US20100292641A1 (en) * | 2009-05-15 | 2010-11-18 | Bandula Wijay | Targeted drug delivery device and method |
WO2011012575A1 (en) * | 2009-07-27 | 2011-02-03 | Scarcell Therapeutics | Balloon catheter device |
WO2011050266A1 (en) | 2009-10-23 | 2011-04-28 | Amorcyte, Inc. | Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency |
US9457171B2 (en) | 2009-12-02 | 2016-10-04 | Renovorx, Inc. | Devices, methods and kits for delivery of therapeutic materials to a target artery |
US10512761B2 (en) | 2009-12-02 | 2019-12-24 | Renovorx, Inc. | Methods for delivery of therapeutic materials to treat pancreatic cancer |
US8821476B2 (en) | 2009-12-02 | 2014-09-02 | Renovorx, Inc. | Devices, methods and kits for delivery of therapeutic materials to a pancreas |
WO2012051489A2 (en) | 2010-10-15 | 2012-04-19 | Cook Medical Technologies Llc | Occlusion device for blocking fluid flow through bodily passages |
US9585667B2 (en) | 2010-11-15 | 2017-03-07 | Vascular Insights Llc | Sclerotherapy catheter with lumen having wire rotated by motor and simultaneous withdrawal from vein |
US10076272B2 (en) | 2011-04-26 | 2018-09-18 | Velano Vascular, Inc. | Systems and methods for phlebotomy through a peripheral IV catheter |
US8366685B2 (en) | 2011-04-26 | 2013-02-05 | Creative Vascular, Llc | Systems and methods for phlebotomy through a peripheral IV catheter |
US11458290B2 (en) | 2011-05-11 | 2022-10-04 | Ekos Corporation | Ultrasound system |
US8888692B1 (en) | 2011-08-26 | 2014-11-18 | Applied Medical Resources Corporation | Trocar cannula assembly and method of manufacture |
WO2013120082A1 (en) | 2012-02-10 | 2013-08-15 | Kassab Ghassan S | Methods and uses of biological tissues for various stent and other medical applications |
JP5508479B2 (en) * | 2012-07-05 | 2014-05-28 | 寛治 井上 | Catheter-type therapeutic / diagnostic instrument with stylet and catheter tube using stylet |
US20140121646A1 (en) * | 2012-10-29 | 2014-05-01 | FABtec Medical, Inc. | Nutrient Absorption Barrier And Delivery Method |
AU2014214700B2 (en) | 2013-02-11 | 2018-01-18 | Cook Medical Technologies Llc | Expandable support frame and medical device |
ES2935345T3 (en) | 2013-03-15 | 2023-03-06 | Applied Med Resources | Trocar Cannula Assembly with Low Profile Insertion Configuration |
WO2014197362A1 (en) | 2013-06-03 | 2014-12-11 | Ramtin Agah | Devices, methods and kits for delivery of therapeutic materials to a pancreas |
US20150038902A1 (en) * | 2013-08-05 | 2015-02-05 | Nico Corporation | Infusion therapy device |
WO2015164455A1 (en) * | 2014-04-23 | 2015-10-29 | Gyrus Acmi, Inc. (D.B.A Olympus Surgical Technologies America) | Stone fragment suction device |
US10661061B2 (en) * | 2014-09-08 | 2020-05-26 | Sanovas Intellectual Property, Llc | Clearance of sinus ostia blockage |
US10092742B2 (en) | 2014-09-22 | 2018-10-09 | Ekos Corporation | Catheter system |
US20160287223A1 (en) * | 2015-04-01 | 2016-10-06 | Boston Scientific Scimed, Inc. | Pulmonary biopsy devices |
CN107708581B (en) | 2015-06-10 | 2021-11-19 | Ekos公司 | Ultrasonic wave guide tube |
EP3551273A1 (en) * | 2016-12-08 | 2019-10-16 | Sanford Health | Slide guide catheter and methods for use thereof |
EP3600514B1 (en) | 2017-03-21 | 2022-06-08 | Velano Vascular, Inc. | Systems and methods for controlling catheter device size |
SG11201907120QA (en) | 2017-03-21 | 2019-10-30 | Velano Vascular Inc | Devices and methods for fluid transfer through a placed peripheral intravenous catheter |
US10695543B2 (en) | 2017-05-18 | 2020-06-30 | Renovorx, Inc. | Methods for treating cancerous tumors |
US11052224B2 (en) | 2017-05-18 | 2021-07-06 | Renovorx, Inc. | Methods for treating cancerous tumors |
US10201689B1 (en) * | 2017-08-07 | 2019-02-12 | Advanced Dilation Strategies, LLC | Urethral balloon dilator catheter |
US20190105474A1 (en) * | 2017-10-08 | 2019-04-11 | Sheibley Medical LLC | Drainage catheter with balloon |
JPWO2019131158A1 (en) * | 2017-12-27 | 2020-12-24 | 株式会社カネカ | Catheter and its manufacturing method |
EP4017571A4 (en) | 2019-08-20 | 2023-11-29 | Velano Vascular, Inc. | Fluid transfer devices with extended length catheters and methods of using the same |
US11696793B2 (en) | 2021-03-19 | 2023-07-11 | Crossfire Medical Inc | Vascular ablation |
CN115463322B (en) * | 2022-09-27 | 2023-11-28 | 广东博迈医疗科技股份有限公司 | Medicine saccule catheter |
US11911581B1 (en) | 2022-11-04 | 2024-02-27 | Controlled Delivery Systems, Inc. | Catheters and related methods for the aspiration controlled delivery of closure agents |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4198981A (en) * | 1978-03-27 | 1980-04-22 | Manfred Sinnreich | Intrauterine surgical device |
WO1983001894A1 (en) * | 1981-11-24 | 1983-06-09 | Weikl, Andreas | Device for eliminating or expanding strictures in vessels conducting body liquids |
US4445892A (en) * | 1982-05-06 | 1984-05-01 | Laserscope, Inc. | Dual balloon catheter device |
DE3915289A1 (en) * | 1989-05-10 | 1990-11-15 | Josef Dieter Dr Med Nagel | Treatment of disorders of alimentary canal - by injection of therapeutic medium into zone sealed by inflatable balloons |
US5129883A (en) * | 1990-07-26 | 1992-07-14 | Michael Black | Catheter |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3948254A (en) * | 1971-11-08 | 1976-04-06 | Alza Corporation | Novel drug delivery device |
US4299226A (en) * | 1979-08-08 | 1981-11-10 | Banka Vidya S | Coronary dilation method |
US4531936A (en) * | 1981-01-29 | 1985-07-30 | Gordon Robert T | Device and method for the selective delivery of drugs to the myocardium |
US4417576A (en) * | 1982-02-25 | 1983-11-29 | Baran Ostap E | Double-wall surgical cuff |
US4423725A (en) * | 1982-03-31 | 1984-01-03 | Baran Ostap E | Multiple surgical cuff |
US4636195A (en) * | 1982-04-02 | 1987-01-13 | Harvey Wolinsky | Method and apparatus for removing arterial constriction |
US4464176A (en) * | 1982-06-04 | 1984-08-07 | Mallinckrodt, Inc. | Blood vessel catheter for medicine delivery and method of manufacture |
US4799479A (en) * | 1984-10-24 | 1989-01-24 | The Beth Israel Hospital Association | Method and apparatus for angioplasty |
US5019075A (en) * | 1984-10-24 | 1991-05-28 | The Beth Israel Hospital | Method and apparatus for angioplasty |
US4824436A (en) * | 1985-04-09 | 1989-04-25 | Harvey Wolinsky | Method for the prevention of restenosis |
EP0220236B1 (en) * | 1985-04-09 | 1994-03-02 | WOLINSKY, Harvey | Method for the prevention of restenosis |
US4708718A (en) * | 1985-07-02 | 1987-11-24 | Target Therapeutics | Hyperthermic treatment of tumors |
US4705709A (en) * | 1985-09-25 | 1987-11-10 | Sherwood Medical Company | Lubricant composition, method of coating and a coated intubation device |
US4655746A (en) * | 1985-12-02 | 1987-04-07 | Target Therapeutics | Catheter device |
JPS62236560A (en) * | 1986-04-09 | 1987-10-16 | テルモ株式会社 | Catheter for repairing blood vessel |
IT8629545V0 (en) * | 1986-06-12 | 1986-06-12 | Fina Ernesto | SET BALLOON URETERAL CATHETER BALLOON FOR EXTRACTION OF URETERAL STONES |
JPH01171571A (en) * | 1987-12-28 | 1989-07-06 | Yoshiharu Yamawaki | Balloon catheter |
DE8904026U1 (en) * | 1988-04-20 | 1989-05-24 | Schneider (Europe) Ag, Zuerich, Ch | |
JPH0255064A (en) * | 1988-08-03 | 1990-02-23 | Toa O | Skin removal for throm bus in blood vessel using catheter and throm bus removing system in blood vessel using catheter |
US4968307A (en) * | 1989-01-09 | 1990-11-06 | Advanced Cardiovascular Systems, Inc. | Catheter for uniform distribution of therapeutic fluids |
US4927418A (en) * | 1989-01-09 | 1990-05-22 | Advanced Cardiovascular Systems, Inc. | Catheter for uniform distribution of therapeutic fluids |
US5021044A (en) * | 1989-01-30 | 1991-06-04 | Advanced Cardiovascular Systems, Inc. | Catheter for even distribution of therapeutic fluids |
EP0383429B1 (en) * | 1989-01-31 | 1995-11-08 | C.R. Bard, Inc. | Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen |
US5087244A (en) * | 1989-01-31 | 1992-02-11 | C. R. Bard, Inc. | Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen |
US4994033A (en) * | 1989-05-25 | 1991-02-19 | Schneider (Usa) Inc. | Intravascular drug delivery dilatation catheter |
HU212760B (en) * | 1989-06-20 | 1997-02-28 | Denes | Method and device for the apportion of chemical materials into the vein wall |
US5242397A (en) * | 1989-06-20 | 1993-09-07 | Cedars-Sinai Medical Center | Catheter device and method of use for intramural delivery of protein kinase C and tyrosine protein kinase inhibitors to prevent restenosis after balloon angioplasty |
US4968306A (en) * | 1989-07-07 | 1990-11-06 | Advanced Cardiovascular Systems, Inc. | Intravascular catheter having an adjustable length infusion section to delivery therapeutic fluid |
US5049132A (en) * | 1990-01-08 | 1991-09-17 | Cordis Corporation | Balloon catheter for delivering therapeutic agents |
US5163905A (en) * | 1990-01-12 | 1992-11-17 | Don Michael T Anthony | Regional perfusion dissolution catheter |
US5176638A (en) * | 1990-01-12 | 1993-01-05 | Don Michael T Anthony | Regional perfusion catheter with improved drug delivery control |
US5222941A (en) * | 1990-01-12 | 1993-06-29 | Don Michael T Anthony | Method of dissolving an obstruction in a vessel |
US5090960A (en) * | 1990-01-12 | 1992-02-25 | Don Michael T Anthony | Regional perfusion dissolution catheter |
US5236413B1 (en) * | 1990-05-07 | 1996-06-18 | Andrew J Feiring | Method and apparatus for inducing the permeation of medication into internal tissue |
US5135484A (en) * | 1990-05-09 | 1992-08-04 | Pioneering Technologies, Inc. | Method of removing plaque from vessels |
US5199951A (en) * | 1990-05-17 | 1993-04-06 | Wayne State University | Method of drug application in a transporting medium to an arterial wall injured during angioplasty |
US5092841A (en) * | 1990-05-17 | 1992-03-03 | Wayne State University | Method for treating an arterial wall injured during angioplasty |
US5180366A (en) * | 1990-10-10 | 1993-01-19 | Woods W T | Apparatus and method for angioplasty and for preventing re-stenosis |
CA2098984C (en) * | 1990-12-28 | 2002-03-05 | Ronald Sahatjian | Drug delivery system |
WO1992011895A1 (en) * | 1990-12-28 | 1992-07-23 | Boston Scientific Corporation | Balloon drug delivery system |
US5102402A (en) * | 1991-01-04 | 1992-04-07 | Medtronic, Inc. | Releasable coatings on balloon catheters |
DE69224636T2 (en) * | 1991-04-24 | 1998-11-05 | Advanced Cardiovascular System | INTERCHANGEABLE BALLOON CATHETER WITH INTEGRATED GUIDE WIRE |
US5213576A (en) * | 1991-06-11 | 1993-05-25 | Cordis Corporation | Therapeutic porous balloon catheter |
CA2074304C (en) * | 1991-08-02 | 1996-11-26 | Cyril J. Schweich, Jr. | Drug delivery catheter |
US5267959A (en) * | 1991-11-29 | 1993-12-07 | Schneider, Inc. | Laser bonding of angioplasty balloon catheters |
US5236424A (en) * | 1992-06-05 | 1993-08-17 | Cardiac Pathways Corporation | Catheter with retractable cannula for delivering a plurality of chemicals |
US5314409A (en) * | 1993-03-11 | 1994-05-24 | Uva Patents Foundation | Catheter for esophageal perfusion |
-
1994
- 1994-04-13 US US08/227,254 patent/US5415636A/en not_active Expired - Lifetime
-
1995
- 1995-01-23 JP JP7526828A patent/JP2930422B2/en not_active Expired - Fee Related
- 1995-01-23 AU AU13914/95A patent/AU699000B2/en not_active Ceased
- 1995-01-23 WO PCT/IB1995/000052 patent/WO1995028196A1/en not_active Application Discontinuation
- 1995-01-23 EP EP95905222A patent/EP0755279A1/en not_active Withdrawn
- 1995-01-23 CA CA002186493A patent/CA2186493C/en not_active Expired - Fee Related
-
1997
- 1997-08-04 US US08/905,873 patent/US5772632A/en not_active Expired - Lifetime
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4198981A (en) * | 1978-03-27 | 1980-04-22 | Manfred Sinnreich | Intrauterine surgical device |
WO1983001894A1 (en) * | 1981-11-24 | 1983-06-09 | Weikl, Andreas | Device for eliminating or expanding strictures in vessels conducting body liquids |
US4445892A (en) * | 1982-05-06 | 1984-05-01 | Laserscope, Inc. | Dual balloon catheter device |
DE3915289A1 (en) * | 1989-05-10 | 1990-11-15 | Josef Dieter Dr Med Nagel | Treatment of disorders of alimentary canal - by injection of therapeutic medium into zone sealed by inflatable balloons |
US5129883A (en) * | 1990-07-26 | 1992-07-14 | Michael Black | Catheter |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9622890B2 (en) | 2012-04-27 | 2017-04-18 | Terumo Kabushiki Kaisha | Catheter for forming biological tissue holding member |
US11602618B2 (en) | 2016-06-01 | 2023-03-14 | Hexacath | Device forming an infusion catheter for treating at least one partial or total obstruction in a passage, such as a body passage |
Also Published As
Publication number | Publication date |
---|---|
CA2186493C (en) | 2000-09-05 |
EP0755279A1 (en) | 1997-01-29 |
JPH09505503A (en) | 1997-06-03 |
AU699000B2 (en) | 1998-11-19 |
US5415636A (en) | 1995-05-16 |
JP2930422B2 (en) | 1999-08-03 |
US5772632A (en) | 1998-06-30 |
MX9604820A (en) | 1998-05-31 |
CA2186493A1 (en) | 1995-10-26 |
AU1391495A (en) | 1995-11-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5415636A (en) | Dilation-drug delivery catheter | |
CA2195214C (en) | Drug delivery and dilation-drug delivery catheters in a rapid exchange configuration | |
EP0920882A2 (en) | Balloon dilatation-drug delivery catheter and stent deployment-drug delivery catheter in rapid exchange configuration | |
EP1351738B1 (en) | Drug delivery catheter having a highly compliant balloon with infusion holes | |
US5728067A (en) | Rapidly exchangeable coronary catheter | |
JP5061614B2 (en) | catheter | |
US5980486A (en) | Rapidly exchangeable coronary catheter | |
US6461347B1 (en) | Low profile catheter shaft | |
US8388640B2 (en) | Catheter with a polymide distal tip | |
US5195971A (en) | Perfusion type dilatation catheter | |
CA2074304C (en) | Drug delivery catheter | |
US20020032406A1 (en) | Catheter for tissue dilatation and drug delivery | |
US20070142819A1 (en) | Bifurcated catheter for agent delivery and method of agent delivery | |
WO1994021320A1 (en) | Fluid delivery catheter | |
WO2003075996A1 (en) | Balloon catheter for tentative vaso-occlusion | |
JP4833039B2 (en) | catheter | |
US7115137B2 (en) | Balloon catheter having a balloon distal skirt section with a reduced outer diameter secured to a soft distal tip member | |
US20030163118A1 (en) | Catheter having a tapered distal tip and method of making | |
JP2003102841A (en) | Balloon catheter | |
AU720826B2 (en) | Drug delivery and dilatation-drug delivery catheters in a rapid exchange configuration | |
CA2247544C (en) | Infusion balloon catheter | |
MXPA96004820A (en) | A catheter for the release of farmaco pordilatac |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AU CA DE JP MX |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2186493 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1995905222 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: PA/a/1996/004820 Country of ref document: MX |
|
WWP | Wipo information: published in national office |
Ref document number: 1995905222 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1995905222 Country of ref document: EP |